How to Save Money on Cyltezo in 2026: Coupons, Discounts, and Patient Assistance

Cyltezo Is Expensive — But You Don't Have to Pay Full Price

Let's start with the number that stops most people in their tracks: Cyltezo (Adalimumab-adbm) costs approximately $7,500 to $7,900 per month without insurance. That's the cash price for a one-month supply — two autoinjector pens or two prefilled syringes.

If you just had a minor heart attack reading that, you're not alone. Biologic medications are among the most expensive drugs on the market. But here's the thing: very few people actually pay that full amount. Between manufacturer copay programs, prescription discount cards, and patient assistance programs, there are real ways to bring your cost down significantly — sometimes to $0.

Here's everything you need to know about saving money on Cyltezo in 2026.

What Does Cyltezo Cost Without Insurance?

Without any insurance or discount program, here's what you can expect to pay for a one-month supply of Cyltezo:

• Cyltezo Pen (2-pack, 40 mg/0.8 mL): ~$7,800
• Cyltezo Prefilled Syringe (2-pack, 40 mg/0.8 mL): ~$7,900
• Cyltezo High-Concentration Pen (2-pack, 40 mg/0.4 mL): ~$7,800

These prices can vary by pharmacy, but they're consistently in the $7,500–$7,900 range. At that rate, a year of Cyltezo without any help would cost over $90,000.

Fortunately, most patients don't pay anywhere near that. Let's look at your options.

Coupons and Discount Cards

Prescription discount cards are free to use and can dramatically reduce your out-of-pocket cost, especially if you don't have insurance or if your plan doesn't cover Cyltezo.

SingleCare

SingleCare offers significant savings on Cyltezo. With a SingleCare coupon, the price for a two-pen or two-syringe kit can drop to approximately $1,288 per month — a savings of over $6,500 off the retail price. No membership or insurance required. Available at singlecare.com.

GoodRx

GoodRx provides free coupons that can bring Cyltezo's price down to $1,200–$1,400 per month at participating pharmacies. Prices vary by location and pharmacy, so compare options on goodrx.com.

Other Discount Programs

Additional discount card options include:

• Optum Perks: Check perks.optum.com for current Cyltezo pricing
• RxSaver: rxsaver.com for pharmacy price comparisons
• BuzzRx: buzzrx.com for coupon cards accepted at most pharmacies

While discount cards bring the price down substantially from $7,900, $1,200+ per month is still a lot of money. If you have insurance or qualify for assistance, you may be able to do much better.

Manufacturer Copay Savings Program

Boehringer Ingelheim, the company that makes Cyltezo, offers a Cyltezo Savings Copay Program for eligible patients with commercial (private) insurance.

Key details:

• Eligible patients may pay as little as $0 per month for Cyltezo
• Available to patients with commercial insurance (not available for Medicare, Medicaid, or other government-funded programs)
• Covers copays, coinsurance, and deductible costs up to the program maximum
• Enroll at patient.boehringer-ingelheim.com/us/products/cyltezo/savings-and-support

This is typically the best deal available for commercially insured patients. If your insurance covers Cyltezo (even with a high copay), the manufacturer's program can bring your cost to zero.

Patient Assistance Programs

If you're uninsured, underinsured, or can't afford your medication even with insurance, patient assistance programs (PAPs) may provide Cyltezo at no cost.

Boehringer Ingelheim Cares Foundation

Boehringer Ingelheim offers a Patient Assistance Program through the BI Cares Foundation for patients who:

• Are uninsured or underinsured
• Meet income eligibility criteria
• Are U.S. residents with a valid prescription

Eligible patients can receive Cyltezo for free. Contact the BI Cares Foundation directly or ask your doctor's office to help you apply.

NeedyMeds

NeedyMeds (needymeds.org) is a nonprofit that maintains a database of patient assistance programs, including those for adalimumab products. Search for "Cyltezo" or "adalimumab" to find current programs.

RxAssist

RxAssist (rxassist.org) is another comprehensive resource for finding patient assistance programs. It includes manufacturer programs, state programs, and nonprofit assistance options.

RxHope

RxHope (rxhope.com) connects patients with manufacturer-sponsored assistance programs and can help you apply directly online.

Other Ways to Save on Cyltezo

Ask About Unbranded Adalimumab-adbm

An unbranded version of Cyltezo's active ingredient (adalimumab-adbm) is available. It's the same medication without the Cyltezo brand name and may be priced lower. Ask your doctor or pharmacist if this option is available and covered by your insurance.

Check If a Different Biosimilar Is Cheaper on Your Plan

If Cyltezo isn't preferred on your insurance formulary, a different adalimumab biosimilar like Amjevita or Hyrimoz might have a lower copay. Your insurance company can tell you which products are on your preferred drug list. Read more about alternatives to Cyltezo.

Use a Specialty Pharmacy With Integrated Copay Support

Many specialty pharmacies automatically apply copay assistance and discount programs when filling biologic prescriptions. When you set up your Cyltezo through a specialty pharmacy, ask them to check all available copay programs on your behalf.

Appeal Insurance Denials

If your insurance denies coverage for Cyltezo, you have the right to appeal. Your doctor's office can submit a letter of medical necessity explaining why Cyltezo is the appropriate treatment. Many initial denials are overturned on appeal.

Review Your Insurance Plan During Open Enrollment

If you're consistently paying high costs for Cyltezo, consider switching to an insurance plan that covers adalimumab biosimilars more favorably. During open enrollment, compare formularies and look specifically at specialty drug coverage tiers.

Quick Cost Comparison

• Cash price (no insurance, no discounts): $7,500–$7,900/month
• With SingleCare or GoodRx coupon: ~$1,200–$1,400/month
• With commercial insurance + manufacturer copay card: As low as $0/month
• With patient assistance program (income-eligible): $0/month

Final Thoughts

Cyltezo's sticker price is daunting, but it doesn't reflect what most patients actually pay. The manufacturer's copay program is the single most impactful tool for commercially insured patients — it can eliminate your out-of-pocket cost entirely. For those without insurance, patient assistance programs can provide the medication at no charge.

Don't let the price tag scare you away from treatment. Explore every option, ask your doctor and pharmacist for help, and use resources like Medfinder to find pharmacies with Cyltezo in stock at the best price.

For more information on finding Cyltezo near you, check out our guide: How to Find Cyltezo in Stock Near You. And if you're a provider, see our provider's guide to helping patients save money on Cyltezo.