Adempas Is One of the Most Expensive Medications You Can Be Prescribed

If you've been prescribed Adempas (Riociguat) for pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH), you may already be feeling the sticker shock. Without insurance, Adempas costs approximately $14,000 to $15,000 per month — that's about $161 per tablet, taken three times a day.

Even with insurance, many patients face steep copays on specialty tier medications. But there are real options to reduce what you pay. This guide covers every savings avenue available for Adempas in 2026, from manufacturer programs to patient assistance foundations.

How Much Does Adempas Cost Without Insurance?

Let's start with the numbers:

• Per tablet: ~$161 (all strengths — 0.5 mg, 1 mg, 1.5 mg, 2 mg, and 2.5 mg — are priced the same)
• Per month (90 tablets): ~$14,471
• Per year: ~$173,000+

These prices are based on the cash (retail) price without insurance or discount programs. For a 9-tablet supply (3 days), the cost starts at approximately $1,454.

Because Adempas is a specialty medication distributed only through REMS-certified pharmacies, traditional coupon cards from websites like GoodRx or SingleCare typically do not apply. Specialty medications require different savings strategies.

Bayer's Aim Copay Assistance Program

The most impactful savings program for commercially insured patients is Bayer's Aim Patient Support Program.

What It Covers

• Eligible commercially insured patients may receive copay assistance covering up to 100% of out-of-pocket costs
• The assistance is paid directly to the insurer or pharmacy on your behalf

How to Enroll

• Call 855-423-3672
• Visit the Aim program page through your specialty pharmacy
• Your prescriber's office can also initiate enrollment as part of the REMS process

Who Qualifies

• Patients with commercial (private) insurance
• Not available to patients on Medicare, Medicaid, TRICARE, or other government-funded insurance programs

If you have commercial insurance and are paying high copays for Adempas, this should be your first call.

Patient Assistance Programs (Free or Reduced-Cost Medication)

If you're uninsured, underinsured, or on a government plan, these programs may help:

Bayer US Patient Assistance Foundation

• What: Provides Adempas at no cost to qualifying patients
• Who qualifies: Uninsured patients who meet income eligibility criteria
• How to apply: Contact the Aim program at 855-423-3672 or ask your doctor's office to submit an application

Patient Access Network (PAN) Foundation

• What: Copay assistance for insured patients who still face high out-of-pocket costs
• Who qualifies: Insured patients with household income between 400-500% of the Federal Poverty Level (approximately $62,400 to $78,000 for an individual in 2026)
• Disease fund: Pulmonary hypertension
• How to apply: Call 866-316-7263 or visit panfoundation.org

Prescription Hope

• What: Helps patients access Adempas for $70 per month
• Who qualifies: Patients who meet income criteria (varies)
• How to apply: Visit prescriptionhope.com or call their enrollment line

NeedyMeds

• What: Free database of patient assistance programs, discount drug cards, and coupons
• How to use: Search for "Riociguat" or "Adempas" at needymeds.org to find all available programs

RxAssist

• What: Comprehensive database of patient assistance programs maintained by Volunteers in Health Care
• How to use: Search at rxassist.org for Adempas-specific programs

Coupons and Discount Cards

Traditional pharmacy discount cards (GoodRx, SingleCare, RxSaver, etc.) generally do not work for Adempas because it's a REMS-restricted specialty medication that cannot be dispensed at retail pharmacies. These coupon platforms are most effective for medications available at traditional pharmacies.

However, it's worth checking these resources for any updated offers:

• Medfinder — check availability and compare specialty pharmacy options
• SaveHealth.com — occasionally lists specialty medication discounts (prices from ~$1,535 for a 9-tablet supply)

The bottom line: for Adempas, manufacturer programs and patient assistance foundations are your most reliable path to savings, not discount cards.

Insurance Tips to Lower Your Costs

Understand Your Plan's Specialty Tier

Most insurance plans place Adempas on their specialty tier, which typically has the highest cost-sharing. Review your plan's formulary to understand:

• Your copay or coinsurance percentage for specialty tier drugs
• Whether you have an annual out-of-pocket maximum that limits total spending
• Whether your plan requires you to use a specific specialty pharmacy

Medicare Part D and the $2,000 Cap

If you're on Medicare Part D, the Inflation Reduction Act's $2,000 annual out-of-pocket cap (effective 2025) may significantly reduce your spending on Adempas. Once you've spent $2,000 out-of-pocket on covered prescriptions in a calendar year, your Part D plan pays 100% for the rest of the year.

This is a major change for Adempas patients on Medicare who previously faced thousands of dollars in costs during the coverage gap (donut hole).

Appeal Insurance Denials

If your insurance denies coverage for Adempas:

1. Ask your doctor to submit a peer-to-peer review with the insurance company's medical director
2. Provide clinical documentation including diagnosis, hemodynamic data, and why Adempas is medically necessary
3. If the internal appeal fails, you may have the right to an external review by an independent third party

Your specialty pharmacy and the Aim program can often assist with the appeals process.

Other Ways to Save on Adempas

Generic Riociguat (Coming Soon)

The FDA has approved a generic version of Riociguat, though it is not yet commercially available as of early 2026. When it launches, generic pricing is expected to be lower than the brand-name cost. However, it will still likely be dispensed through REMS-certified specialty pharmacies. Keep in touch with your prescriber for updates.

Ask About Samples

Some prescribers may have access to limited supplies of Adempas samples from Bayer. While not a long-term solution, samples can help bridge gaps during insurance processing or enrollment in assistance programs.

Explore State Pharmaceutical Assistance Programs (SPAPs)

Some states operate their own prescription assistance programs that can supplement Medicare Part D or provide additional coverage. Check with your state's department of health or aging services to see if you qualify.

Employer Assistance

If you have employer-sponsored insurance, check whether your employer offers a specialty medication support program or health advocacy service. Some larger employers contract with specialty pharmacy navigators who can help reduce your costs.

Final Thoughts

Adempas is expensive — there's no getting around that. At $14,000 to $15,000 per month, it's one of the highest-cost prescription medications available. But between Bayer's Aim copay program, patient assistance foundations, and Medicare's $2,000 cap, most patients can find a way to make it affordable.

Here's your action plan:

1. If commercially insured: Call Bayer's Aim program at 855-423-3672 for copay assistance
2. If uninsured: Apply to the Bayer US Patient Assistance Foundation for free medication
3. If on Medicare: Verify you benefit from the $2,000 out-of-pocket cap; check PAN Foundation eligibility
4. If denied by insurance: Work with your doctor to file an appeal

Don't let cost keep you from taking a medication your doctor has prescribed. Use Medfinder to find Adempas in stock, and explore all available savings programs before paying cash.

Related guides: Why Adempas is hard to find | Alternatives to Adempas | What is Adempas?