

A practical guide for providers: help patients find Eliquis in stock, navigate availability challenges, and maintain anticoagulation therapy in 2026.
As a prescriber, few things are more frustrating than learning that a patient can't fill a critical medication. Eliquis (Apixaban) — the most prescribed oral anticoagulant in the US — is increasingly the subject of patient complaints about pharmacy availability. While there is no formal shortage, the reality on the ground is that many patients are struggling to find it.
Given Eliquis's boxed warning about the risk of thrombotic events upon premature discontinuation, ensuring therapy continuity is a clinical imperative. This guide provides practical, actionable steps your team can take to help patients maintain access.
Eliquis is not on the FDA or ASHP shortage lists. Bristol-Myers Squibb and Pfizer continue manufacturing both the 2.5 mg and 5 mg tablet formulations. The availability challenge is at the pharmacy level — driven by:
Understanding the root causes helps you advise patients effectively:
Large chain pharmacies receive shipments from wholesalers on fixed schedules. Between deliveries, popular medications like Eliquis can sell out. Independent pharmacies tend to have more flexibility in ordering but may carry smaller quantities overall.
When patients change insurance plans (common in January), they may be required to use a different pharmacy network. The new pharmacy may not have anticipated their prescription, leading to stock-outs.
Some patients delay filling because of out-of-pocket costs, especially during the "donut hole" phase of Medicare Part D or when facing high commercial copays. When they do fill, it can create unpredictable demand patterns.
Make medication access a standard part of your clinical workflow. At each visit, ask:
Many patients won't volunteer this information unless asked directly.
Medfinder for Providers helps clinical teams locate pharmacies with Eliquis in stock. You can search by the patient's ZIP code to find nearby options. This is faster than calling pharmacies individually and can be done by clinical staff during the visit or at checkout.
For patients who want to search on their own, direct them to medfinder.com.
Simple prescribing adjustments can reduce access barriers:
For patients who report gaps in therapy, have a plan ready:
Cost is often the hidden barrier. Ensure your team is aware of:
For a comprehensive patient-facing resource, share How to Save Money on Eliquis in 2026. Providers can also reference our provider's guide to helping patients save money on Eliquis.
When switching is clinically appropriate, the main alternatives to Eliquis include:
Follow ACC/AHA transition guidelines when switching between anticoagulants. For patient-facing alternative information, share Alternatives to Eliquis.
Eliquis access challenges in 2026 are real but manageable. The combination of proactive patient conversations, availability tools like Medfinder, established bridge protocols, and awareness of financial resources can keep your patients on therapy safely.
The landscape should improve as the supply chain adapts to new Medicare pricing and especially when generic Apixaban launches (projected April 2028). Until then, provider engagement is the key to closing the gap between prescription and pharmacy shelf.
For more on the overall Eliquis landscape in 2026, see our provider shortage briefing and the patient-facing shortage update.
You focus on staying healthy. We'll handle the rest.
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