How to Help Your Patients Find Eliquis in Stock: A Provider's Guide

Updated:

February 14, 2026

Author:

Peter Daggett

Summarize this blog with AI:

A practical guide for providers: help patients find Eliquis in stock, navigate availability challenges, and maintain anticoagulation therapy in 2026.

Your Patients Can't Find Eliquis — Here's How You Can Help

As a prescriber, few things are more frustrating than learning that a patient can't fill a critical medication. Eliquis (Apixaban) — the most prescribed oral anticoagulant in the US — is increasingly the subject of patient complaints about pharmacy availability. While there is no formal shortage, the reality on the ground is that many patients are struggling to find it.

Given Eliquis's boxed warning about the risk of thrombotic events upon premature discontinuation, ensuring therapy continuity is a clinical imperative. This guide provides practical, actionable steps your team can take to help patients maintain access.

Current Availability Landscape

Eliquis is not on the FDA or ASHP shortage lists. Bristol-Myers Squibb and Pfizer continue manufacturing both the 2.5 mg and 5 mg tablet formulations. The availability challenge is at the pharmacy level — driven by:

  • Record-high prescription volume: Eliquis prescriptions continue to grow as more patients are diagnosed with AFib and VTE
  • Medicare pricing transition: The negotiated price ($231/month, effective January 2026) has caused inventory and purchasing adjustments across the supply chain
  • Single-source brand: With no generic on the market until an expected April 2028 launch, all demand concentrates on one product
  • Q1 formulary disruption: Annual insurance plan changes drive prescription volume spikes and coverage confusion in January and February

Why Patients Can't Find Eliquis

Understanding the root causes helps you advise patients effectively:

Pharmacy Stocking Patterns

Large chain pharmacies receive shipments from wholesalers on fixed schedules. Between deliveries, popular medications like Eliquis can sell out. Independent pharmacies tend to have more flexibility in ordering but may carry smaller quantities overall.

Insurance-Driven Pharmacy Switching

When patients change insurance plans (common in January), they may be required to use a different pharmacy network. The new pharmacy may not have anticipated their prescription, leading to stock-outs.

Cost-Related Delays

Some patients delay filling because of out-of-pocket costs, especially during the "donut hole" phase of Medicare Part D or when facing high commercial copays. When they do fill, it can create unpredictable demand patterns.

What Providers Can Do: 5 Practical Steps

Step 1: Ask About Access at Every Visit

Make medication access a standard part of your clinical workflow. At each visit, ask:

  • "Are you having any trouble getting your Eliquis filled?"
  • "Have you had any gaps in taking your medication?"
  • "Has the cost of your medication changed recently?"

Many patients won't volunteer this information unless asked directly.

Step 2: Direct Patients to Medfinder

Medfinder for Providers helps clinical teams locate pharmacies with Eliquis in stock. You can search by the patient's ZIP code to find nearby options. This is faster than calling pharmacies individually and can be done by clinical staff during the visit or at checkout.

For patients who want to search on their own, direct them to medfinder.com.

Step 3: Prescribe for Flexibility

Simple prescribing adjustments can reduce access barriers:

  • Allow pharmacy flexibility: E-prescribe to the patient's preferred pharmacy but note that it can be transferred if needed
  • Write 90-day prescriptions: Longer fills reduce the number of potential stock-out encounters and are available through mail-order pharmacies
  • Include DAW 0 (or equivalent): While no generic is currently available, ensuring the prescription allows substitution positions patients for a seamless transition when generic Apixaban launches

Step 4: Establish Bridge Protocols

For patients who report gaps in therapy, have a plan ready:

  • Office samples: If available, dispense samples to cover the gap
  • Pharmacist collaboration: Contact the patient's pharmacy to arrange an emergency supply (many states allow pharmacists to provide a short-term emergency fill)
  • Temporary therapeutic switch: If the gap will extend beyond 48-72 hours, consider temporary transition to an available alternative (see below)
  • Document the plan: Chart the contingency so any covering provider can act quickly

Step 5: Connect Patients with Financial Resources

Cost is often the hidden barrier. Ensure your team is aware of:

  • Eliquis Co-Pay Card: $0 copay for eligible commercially insured patients (valid through 12/31/2026)
  • Eliquis 360 Direct-to-Patient: >40% off list price for cash-paying patients (855-354-7847)
  • BMS Patient Assistance Foundation: Free medication for qualifying uninsured/underinsured patients (1-800-736-0003)
  • Medicare negotiated price: ~$231/month with $2,000/year out-of-pocket cap
  • Discount programs: SingleCare, GoodRx, and other platforms offer savings on cash prices

For a comprehensive patient-facing resource, share How to Save Money on Eliquis in 2026. Providers can also reference our provider's guide to helping patients save money on Eliquis.

Therapeutic Alternatives

When switching is clinically appropriate, the main alternatives to Eliquis include:

  • Xarelto (Rivaroxaban): Factor Xa inhibitor, once-daily dosing, similar efficacy and safety profile. Also brand-only. Good option when dosing simplicity is valued.
  • Pradaxa (Dabigatran): Direct thrombin inhibitor, twice daily. Specific reversal agent (Praxbind) is an advantage in high-bleeding-risk patients.
  • Savaysa (Edoxaban): Factor Xa inhibitor, once daily. Avoid in AFib patients with CrCl >95 mL/min. Requires parenteral lead-in for DVT/PE.
  • Warfarin: Extremely low cost ($4-$10/month). Requires INR monitoring. Consider when cost is the dominant barrier and monitoring is feasible.

Follow ACC/AHA transition guidelines when switching between anticoagulants. For patient-facing alternative information, share Alternatives to Eliquis.

Workflow Tips for Your Practice

  • Create a pharmacy availability reference sheet for front desk and nursing staff with links to Medfinder for Providers and the Eliquis support hotline (855-354-7847)
  • Flag Eliquis patients in your EHR for proactive outreach when availability reports change
  • Batch check patient refill status during care coordination time, especially in January when formulary changes peak
  • Keep a small sample stock of Eliquis for emergency bridge situations
  • Educate MA/nursing staff on the savings programs so they can connect patients during rooming

Final Thoughts

Eliquis access challenges in 2026 are real but manageable. The combination of proactive patient conversations, availability tools like Medfinder, established bridge protocols, and awareness of financial resources can keep your patients on therapy safely.

The landscape should improve as the supply chain adapts to new Medicare pricing and especially when generic Apixaban launches (projected April 2028). Until then, provider engagement is the key to closing the gap between prescription and pharmacy shelf.

For more on the overall Eliquis landscape in 2026, see our provider shortage briefing and the patient-facing shortage update.

Is there a clinical protocol for bridging patients off Eliquis temporarily?

There is no single universal protocol, but ACC/AHA guidelines provide recommendations for transitioning between anticoagulants. For short gaps (24-48 hours), the risk varies by indication — AFib patients at high stroke risk may need more urgent bridging than post-DVT patients on chronic therapy. Consult current guidelines and consider the patient's individual thromboembolic risk.

Can pharmacists provide emergency supplies of Eliquis?

Most states allow pharmacists to dispense a short-term emergency supply of chronic medications (typically 3-7 days) when a patient cannot reach their prescriber. The specific rules vary by state. Encourage patients to ask their pharmacist about emergency fill options if they face a gap.

Should I proactively switch patients to a different anticoagulant in anticipation of access issues?

Generally, no. Eliquis remains available and is not in formal shortage. Proactive switching introduces unnecessary transition risk. Instead, establish contingency plans and educate patients about what to do if they can't find it. Reserve switching for patients who are actively unable to maintain Eliquis therapy.

How can I help my uninsured patients afford Eliquis?

Direct them to the BMS Patient Assistance Foundation (1-800-736-0003) for potentially free medication, the Eliquis 360 direct-to-patient program for >40% off list price (855-354-7847), or discount programs like SingleCare and GoodRx that can reduce cash prices to approximately $155-$350 per month.

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