Your Patients Can't Find Dyanavel XR — Here's How You Can Help

The ongoing amphetamine shortage has put providers in a difficult position. You prescribe Dyanavel XR because it's the right medication for your patient — but they call back a day later saying no pharmacy has it. This scenario has played out thousands of times since the shortage began in late 2022.

As a prescriber, you have more leverage than you might think. This guide covers practical steps you can take to help your patients locate Dyanavel XR, along with workflow strategies and alternative therapy options when the medication simply isn't available.

Current Dyanavel XR Availability

As of early 2026, Dyanavel XR availability remains inconsistent nationwide. Key factors:

• Single-source product: Tris Pharma is the sole manufacturer. No generic exists.
• Formulations: Extended-release tablets (5 mg, 10 mg, 15 mg, 20 mg) and extended-release oral suspension (2.5 mg/mL).
• Chain vs. independent: Large chains often don't stock Dyanavel XR due to low demand relative to generics. Independent pharmacies are more likely to carry or order it.
• Regional variation: Availability fluctuates by region and changes week to week.

For the full shortage background, see our provider shortage briefing.

Why Patients Can't Find Dyanavel XR

Understanding the barriers your patients face helps you intervene more effectively:

1. Pharmacies don't stock it. Many chain pharmacies prioritize high-volume generics and may not carry brand-only products like Dyanavel XR.
2. Patients don't know where to look. Most patients start (and end) their search at one or two familiar pharmacies.
3. Schedule II restrictions. Prescriptions can't be transferred between pharmacies and often can't be called in, limiting flexibility.
4. Cost barriers. At $460–$590/month cash price, some pharmacies may not stock a product patients might not be able to afford.
5. Timing. Patients often wait until they're nearly out of medication before trying to refill, leaving no buffer for supply issues.

5 Steps Providers Can Take to Help

Step 1: Check Availability Before Sending the Prescription

Use Medfinder for Providers to search for pharmacies that currently have Dyanavel XR in stock near your patient's location. By identifying a pharmacy with stock before e-prescribing, you eliminate the most common failure point.

This takes less than a minute and can save your patient hours of phone calls and days of missed medication.

Step 2: E-Prescribe to the Right Pharmacy

Once you've identified a pharmacy with Dyanavel XR in stock, send the electronic prescription directly there. Confirm with your patient which location works for them, and let them know to pick it up promptly — stimulant inventory can move quickly.

Step 3: Proactively Discuss the Savings Card

Many patients don't know about the Tris Pharma Savings Card, which can reduce their out-of-pocket cost to $25/month. Mention this during the visit, especially for commercially insured and uninsured patients. Patients can activate the card at trissavingscard.com.

Note: The savings card is not available for patients on Medicare, Medicaid, or Tricare.

Step 4: Have a Contingency Plan Ready

Document a backup plan in the patient's chart. If Dyanavel XR becomes unavailable at refill time, what alternative would you prescribe? Having this documented means your staff can act quickly rather than waiting for a provider callback.

Common contingency options include:

• Adderall XR (generic mixed amphetamine salts) — widest availability
• Vyvanse (generic lisdexamfetamine) — good availability, smoother profile
• Adzenys XR-ODT — if an orally disintegrating form is needed
• Quillivant XR — if a liquid stimulant is specifically needed (methylphenidate-based)

Step 5: Educate Patients on Proactive Refills

Encourage patients to begin the refill process 7–10 days before running out. Provide them with resources:

• Direct them to Medfinder for pharmacy availability searches
• Suggest independent pharmacies as a first option
• Remind them that Schedule II prescriptions cannot be transferred

For a patient-friendly version of this advice, share our article on how to find Dyanavel XR in stock.

Alternatives When Dyanavel XR Isn't Available

When switching is necessary, consider these factors:

• Formulation need: Does the patient specifically require a liquid? Dyanavel XR oral suspension is one of the only extended-release amphetamine liquids available. Quillivant XR is a liquid alternative but is methylphenidate-based.
• Dose conversion: Dyanavel XR is not interchangeable mg-per-mg with Adderall XR or other mixed amphetamine salts. Retitration may be necessary.
• Duration of action: Dyanavel XR provides approximately 12–13 hours of coverage. Vyvanse offers up to 14 hours; Mydayis up to 16 hours.
• Insurance coverage: Check the patient's formulary before switching. Some alternatives may require their own prior authorizations.

See our full alternatives guide for more details.

Workflow Tips for Your Practice

Consider integrating these practices into your clinic workflow:

• Bookmark Medfinder for Providers on your prescribing workstation for quick availability checks.
• Create a shortage protocol for your practice that includes preferred alternatives, contingency plans, and patient education materials.
• Pre-authorize alternatives when possible. If your patient's insurer covers generic Adderall XR or generic Vyvanse without PA, having that as a documented backup saves time during a shortage-related scramble.
• Train front office staff to direct patients to Medfinder when they call about medication availability issues, reducing provider callbacks.
• Use the prior authorization process strategically. When submitting PAs for Dyanavel XR, emphasize the liquid formulation need, treatment history, and clinical rationale. Strong documentation improves approval rates.

Final Thoughts

The Dyanavel XR shortage is a systems-level problem, but individual provider actions can make a meaningful difference for patients. By integrating availability checks into your prescribing workflow, maintaining contingency plans, and leveraging tools like Medfinder for Providers, you can help ensure your patients don't fall through the cracks.

For the latest shortage data and clinical guidance, see our comprehensive provider shortage update. For cost-saving strategies you can share with patients, see our guide on helping patients save money on Dyanavel XR.