

Is Auvelity XR in shortage in 2026? Get the latest update on availability, pricing, and what you can do to find and afford your antidepressant prescription.
If you take Auvelity XR for major depressive disorder, here's what you need to know about availability in 2026. Whether you're having trouble filling your prescription or just want to plan ahead, this guide covers the current status, pricing, and practical steps to stay on your medication.
As of early 2026, Auvelity XR is not listed on the FDA drug shortage database. This means there is no official, nationwide shortage of the medication. Axsome Therapeutics, the manufacturer, continues to produce and distribute Auvelity XR.
However, many patients are still experiencing difficulty finding Auvelity XR at their local pharmacies. This is a localized availability issue rather than a true manufacturing shortage — the medication exists in the supply chain, but not every pharmacy stocks it.
Even without an official shortage, several factors contribute to spotty pharmacy availability:
Pharmacies order medications through wholesalers, and these wholesalers may limit quantities of high-cost brand-name drugs. If a pharmacy hasn't previously stocked Auvelity XR, it may take additional time and effort to establish an ordering relationship.
As more doctors prescribe Auvelity XR — particularly psychiatrists treating patients who haven't responded to traditional antidepressants — demand in certain areas can exceed what local pharmacies have on hand.
At roughly $900-$1,300 per month retail, Auvelity XR is an expensive medication for pharmacies to stock. Many pharmacies, especially chain locations, avoid carrying drugs they don't regularly dispense because of the financial risk.
The retail cash price for Auvelity XR typically ranges from $900 to $1,300 per month, depending on the pharmacy. This is for the standard maintenance dose of 45 mg/105 mg tablets taken twice daily.
Insurance coverage for Auvelity XR varies significantly by plan. Many insurers place it on a Tier 3 (preferred brand) or specialty tier, with copays ranging from $50 to $150+ per month. Most plans require:
Axsome Therapeutics offers an Auvelity Savings Card that may reduce your out-of-pocket cost to as little as $10 per fill for eligible commercially insured patients. Visit auvelity.com/savings for details and to check your eligibility.
For uninsured or underinsured patients, the Axsome Patient Assistance Program may provide Auvelity XR at no cost for those who qualify based on income. Additional resources include NeedyMeds and RxAssist.
For a complete breakdown of savings options, see our guide: How to Save Money on Auvelity XR.
There is currently no generic version of Auvelity XR available, and none is expected in the near term due to patent protection. However, the antidepressant landscape continues to evolve:
If your pharmacy doesn't have Auvelity XR, here are actionable steps to find it:
Medfinder is the fastest way to locate Auvelity XR in stock near you. Their dedicated team contacts pharmacies on your behalf — no need to make dozens of phone calls yourself.
Independent pharmacies often have more flexibility with their inventory. They may already stock Auvelity XR or be willing to order it for you within a few business days.
Contact your pharmacy at least one week before your refill is due. This gives them time to order Auvelity XR from their wholesaler if they don't have it on hand. Don't wait until you're running out.
If the pharmacy doesn't have one particular strength or count, ask if they have others available. Your doctor may be able to adjust your prescription slightly to match what's in stock.
Here are the key takeaways for Auvelity XR in 2026:
For more information:
You focus on staying healthy. We'll handle the rest.
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