Can't find Estarylla 28 Day? Here are the best alternatives — including equivalent generics and other birth control options to discuss with your doctor.
Your pharmacy is out of Estarylla 28 Day, and you need your birth control. This is stressful, but here's the good news: there are several alternatives that contain the exact same active ingredients and others that work in very similar ways. You don't have to go without contraception.
In this guide, we'll explain what Estarylla 28 Day is, how it works, and walk you through the best alternatives you can discuss with your doctor or pharmacist.
Estarylla 28 Day is a monophasic combination oral contraceptive made by Sandoz Inc. Each pack contains 21 active tablets with Norgestimate 0.25 mg and Ethinyl Estradiol 0.035 mg, plus 7 inert (inactive) tablets. It's a branded generic equivalent of Ortho-Cyclen.
Estarylla is FDA-approved for:
It's also commonly used off-label to regulate irregular periods, reduce menstrual cramps, manage endometriosis symptoms, and decrease the risk of ovarian cysts.
Estarylla works through three mechanisms:
Understanding how Estarylla works helps explain why certain alternatives are good substitutes — they use the same or similar mechanisms. For a deeper dive, see our post on how Estarylla 28 Day works.
The following medications contain the exact same active ingredients (Norgestimate 0.25 mg and Ethinyl Estradiol 0.035 mg) in the same monophasic formulation as Estarylla. Your pharmacist can often substitute these without a new prescription.
Sprintec is one of the most widely prescribed branded generics of Norgestimate/Ethinyl Estradiol. It contains the same hormones at the same doses as Estarylla and is manufactured by Teva Pharmaceuticals. Because it's so commonly prescribed, Sprintec tends to be well-stocked at most pharmacies.
Previfem is another branded generic equivalent of Ortho-Cyclen, manufactured by Mylan (now Viatris). It has the same active ingredients, same doses, and same 21-active/7-inert tablet configuration as Estarylla.
Mono-Linyah is manufactured by Northstar Rx and is yet another branded generic equivalent. Same formulation, same dosing schedule.
If none of the direct equivalents are available either, these alternatives use similar hormones or slightly different formulations. You'll need your prescriber to write a new prescription for these.
Tri-Sprintec is the generic equivalent of Ortho Tri-Cyclen. It contains the same two hormones as Estarylla but in a triphasic formulation — meaning the dose of Norgestimate changes across three phases of the cycle (0.18 mg, 0.215 mg, and 0.25 mg) while Ethinyl Estradiol stays at 0.035 mg.
Some women prefer triphasic pills because the varying hormone levels more closely mimic the natural menstrual cycle. Others do fine on either formulation.
These combination pills use a different progestin — Levonorgestrel — paired with Ethinyl Estradiol. Levonorgestrel is one of the oldest and most studied progestins. These pills are widely available and very affordable.
If you're open to a non-pill option, NuvaRing is a flexible vaginal ring that releases hormones continuously for three weeks. You insert it yourself, leave it in for 21 days, remove it for 7 days, then start a new one. It uses different hormones (Etonogestrel and Ethinyl Estradiol) but works through the same mechanism.
Before switching, talk to your doctor or pharmacist. Here's what to keep in mind:
Not being able to find Estarylla 28 Day is frustrating, but it doesn't mean you're out of options. Several medications contain the exact same active ingredients, and others offer very similar protection. The key is to act quickly — talk to your pharmacist about direct substitutes, or contact your prescriber for a new prescription if needed.
Use Medfinder to check which medications are available near you, and read our guide on how to find Estarylla 28 Day in stock for additional strategies.
You focus on staying healthy. We'll handle the rest.
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