Alternatives to Benazepril If You Can't Fill Your Prescription

Updated:

March 27, 2026

Author:

Peter Daggett

Summarize this blog with AI:

Can't find Benazepril? Learn about effective alternatives like Lisinopril, Enalapril, Ramipril, and Losartan that your doctor may recommend instead.

Can't Fill Your Benazepril Prescription? Here Are Your Options

Whether it's a pharmacy stock-out, a supply chain hiccup, or an insurance issue, there are many reasons you might not be able to fill your Benazepril prescription. Whatever the cause, going without blood pressure medication is never a good idea. Uncontrolled hypertension raises your risk of stroke, heart attack, and kidney damage.

The good news is that Benazepril isn't the only medication in its class. There are several safe and effective alternatives your doctor can prescribe. Let's walk through what Benazepril does, how it works, and the best alternatives available in 2026.

What Is Benazepril?

Benazepril (brand name Lotensin) is a prescription medication used to treat high blood pressure (hypertension) in adults and children ages 6 and older. It belongs to a class of drugs called ACE inhibitors — one of the most widely prescribed classes of blood pressure medications in the world.

Benazepril is available as a generic, which makes it affordable for most patients. It comes in 5 mg, 10 mg, 20 mg, and 40 mg tablets and is typically taken once or twice daily. For a deeper look at the drug, check out our guide on what Benazepril is, its uses, and dosage.

How Does Benazepril Work?

Benazepril works by blocking angiotensin-converting enzyme (ACE), a protein that plays a key role in raising blood pressure. Normally, ACE converts a substance called angiotensin I into angiotensin II, a powerful chemical that narrows blood vessels and tells your body to retain salt and water. By blocking this process, Benazepril helps blood vessels relax, reduces fluid retention, and lowers blood pressure.

ACE inhibitors also preserve bradykinin, a natural substance that helps blood vessels widen. This dual action makes them effective at lowering blood pressure, protecting the kidneys, and reducing strain on the heart. For more details, see our article on how Benazepril works.

Alternatives to Benazepril

If you can't get Benazepril, your doctor has several options. The closest alternatives are other ACE inhibitors, which work by the same mechanism. If you can't tolerate ACE inhibitors at all (for example, because of persistent cough), your doctor may recommend an ARB instead.

1. Lisinopril (Zestril, Prinivil)

Lisinopril is the most commonly prescribed ACE inhibitor in the United States and the most widely available. Like Benazepril, it lowers blood pressure by blocking ACE. Key differences include:

  • Not processed by the liver: Unlike Benazepril, Lisinopril is not metabolized in the liver. This makes it a better choice for patients with liver disease or cirrhosis.
  • Available as a liquid: Lisinopril comes in an oral solution (Qbrelis), which can be helpful for patients who have trouble swallowing tablets.
  • Very affordable: Generic Lisinopril costs as little as $3 to $7 for a 30-day supply with a discount coupon.
  • Taken once daily: Lisinopril is typically taken once a day, making it convenient.

Lisinopril is FDA-approved for hypertension, heart failure, and improving survival after a heart attack. It's a close substitute for Benazepril in most patients.

2. Enalapril (Vasotec, Epaned)

Enalapril is another well-established ACE inhibitor with decades of clinical evidence. It's one of the most studied ACE inhibitors for heart failure. Key features:

  • Proven heart failure benefits: Enalapril was one of the first ACE inhibitors shown to significantly reduce deaths in heart failure patients.
  • Available as oral solution: Epaned is an FDA-approved oral solution of Enalapril, useful for children and adults who can't swallow pills.
  • Taken once or twice daily: Depending on the dose and indication, your doctor may prescribe it once or twice a day.
  • Affordable generic: Generic Enalapril costs approximately $4 to $10 for a 30-day supply with a coupon.

3. Ramipril (Altace)

Ramipril is an ACE inhibitor with particularly strong evidence for cardiovascular protection. The landmark HOPE trial showed that Ramipril significantly reduced the risk of heart attacks, strokes, and cardiovascular death in high-risk patients. Highlights include:

  • Strong heart protection: Especially recommended for patients at high cardiovascular risk, including those with diabetes.
  • Flexible dosing: Capsules can be opened and sprinkled on applesauce for patients who have difficulty swallowing.
  • Once-daily dosing: Typically taken once a day.
  • Generic available: Costs approximately $5 to $15 for a 30-day supply with a coupon.

4. Losartan (Cozaar)

If you've experienced side effects from ACE inhibitors — particularly the dry, persistent cough that affects up to 10-15% of ACE inhibitor users — your doctor may recommend switching to an ARB (angiotensin II receptor blocker) instead.

Losartan is the most commonly prescribed ARB. It works on the same blood pressure pathway but at a different point, blocking the action of angiotensin II rather than preventing its production. This means it doesn't cause the buildup of bradykinin that triggers the cough. Key points:

  • No ACE inhibitor cough: The most common reason doctors switch patients from an ACE inhibitor to an ARB.
  • Kidney protection: FDA-approved for diabetic nephropathy, making it a strong choice for patients with diabetes and kidney disease.
  • Very affordable: Generic Losartan costs as little as $4 to $8 for a 30-day supply.
  • Once-daily dosing: Typically taken once a day.

Important: Don't Switch Medications on Your Own

While all of these medications treat high blood pressure, they are not identical. Dosing, side effects, and drug interactions vary between them. Always talk to your doctor or healthcare provider before switching medications. Your doctor will consider your medical history, kidney function, other medications, and overall health before recommending an alternative.

If you need a new prescription quickly, consider finding a doctor or telehealth provider who can help.

Final Thoughts

Not being able to fill your Benazepril prescription is frustrating, but it's not a dead end. Lisinopril, Enalapril, Ramipril, and Losartan are all effective, affordable alternatives that your doctor can prescribe. Many of these medications are even more widely available than Benazepril.

Before switching, try using Medfinder to see if another pharmacy near you has Benazepril in stock. If it's truly unavailable, work with your healthcare provider to find the right alternative for you.

Related reading:

What is the closest alternative to Benazepril?

Lisinopril is the closest and most widely available alternative to Benazepril. Both are ACE inhibitors that work by the same mechanism. Lisinopril is the most commonly prescribed ACE inhibitor in the U.S. and is available as an affordable generic, often costing as little as $3 to $7 per month with a discount coupon.

Can I switch from Benazepril to Losartan?

Yes, but only with your doctor's guidance. Losartan is an ARB, not an ACE inhibitor, so it works at a different point in the same blood pressure pathway. It's a good option if you've experienced the persistent dry cough that some ACE inhibitor users develop. Your doctor will determine the right Losartan dose for you.

Are Benazepril alternatives as effective at lowering blood pressure?

Yes. Lisinopril, Enalapril, Ramipril, and Losartan are all proven to effectively lower blood pressure. Clinical studies show that ACE inhibitors and ARBs provide similar blood pressure reduction. Your doctor will choose the best option based on your individual health needs.

Do I need a new prescription to switch from Benazepril to an alternative?

Yes, you'll need a new prescription from your doctor to switch to a different medication. Your pharmacist cannot substitute one ACE inhibitor for another without a new prescription. Contact your doctor's office or a telehealth provider to discuss your options and get a new prescription quickly.

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