Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Trifluridine is an antiviral ophthalmic solution used to treat eye infections caused by herpes simplex virus (HSV) types 1 and 2. It is specifically approved for primary keratoconjunctivitis and recurrent epithelial keratitis. Trifluridine is applied as eye drops directly to the affected eye and is available as a generic medication. The brand-name version was sold as Viroptic.
Trifluridine is a fluorinated pyrimidine nucleoside analogue — a modified form of deoxyuridine. When herpes simplex virus replicates in the eye, Trifluridine gets incorporated into the viral DNA. The trifluoromethyl group blocks normal base pairing, which interferes with viral DNA synthesis and halts the replication process, allowing the eye to heal.
Trifluridine has a findability score of 45 out of 100, meaning it can be moderately difficult to locate. Only a limited number of manufacturers produce the ophthalmic formulation, making it vulnerable to periodic supply disruptions. Patients may need to call multiple pharmacies or use Medfinder to locate a pharmacy with Trifluridine in stock.
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Trifluridine is most commonly prescribed by ophthalmologists and optometrists who diagnose and treat herpetic eye infections. Emergency medicine physicians may also prescribe it when patients present with acute herpes simplex keratitis. Telehealth prescribing is generally not available for this medication since an in-person eye examination is typically required.
No, Trifluridine is not a controlled substance. It does not have a DEA schedule and is not subject to the prescribing restrictions that apply to controlled medications. A standard prescription from a licensed prescriber is all that is needed.
Serious but rare side effects include hypersensitivity reactions, stromal edema, increased intraocular pressure, and dry eye. Treatment should not exceed 21 consecutive days.
Trifluridine ophthalmic solution has no clinically significant drug interactions due to its negligible systemic absorption when used as directed. The medication acts locally on the eye, so it does not typically interact with oral medications. However, patients should inform their eye doctor of all medications they are using, including other eye drops, to avoid potential local interactions.
Trifluridine remains an important antiviral treatment for herpes simplex eye infections, but its limited manufacturing base means it can be difficult to find in stock. With a cash price of $201 to $400 per bottle, using discount coupons or insurance coverage can significantly reduce costs. If your pharmacy is out of stock, Medfinder can help you locate a nearby pharmacy that has Trifluridine available. Always store this medication refrigerated and follow your ophthalmologist's instructions carefully.
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