Comprehensive medication guide to Tirosint including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$25–$75 copay on Tier 3; many plans require prior authorization or step therapy through generic Levothyroxine tablets first.
Estimated Cash Pricing
$150–$250 retail for 30 capsules; as low as $65/month through Tirosint Direct or $25/month with the Tirosint Copay Savings Card.
Medfinder Findability Score
62/100
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Tirosint is a brand-name prescription medication containing Levothyroxine Sodium in a unique gel capsule formulation. It is manufactured by IBSA Pharma and is used as thyroid hormone replacement therapy for patients with hypothyroidism (underactive thyroid). It is also used as an adjunct to surgery and radioiodine therapy for the management of certain thyroid cancers.
What sets Tirosint apart from standard Levothyroxine tablets is its minimal inactive ingredients — containing only gelatin, glycerin, and water. This makes it an excellent option for patients with absorption issues, food sensitivities, or allergies to dyes and fillers found in conventional tablets.
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![How to Find a Doctor Who Can Prescribe Tirosint Near You [2026 Guide]](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2Fvur4atr4%2Fproduction%2F6e6cedcb9323e4e3e36d0bc77a7052cdbc001101-1024x1024.png%3Frect%3D0%2C256%2C1024%2C512%26w%3D400%26h%3D200%26auto%3Dformat&w=828&q=75)
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Tirosint contains synthetic Levothyroxine (T4), which is chemically identical to the thyroxine naturally produced by the thyroid gland. Once absorbed, T4 is converted to the active hormone triiodothyronine (T3) in peripheral tissues. Thyroid hormones regulate metabolism, protein synthesis, growth, and development by binding to nuclear thyroid hormone receptors and influencing gene expression.
Tirosint's gel capsule formulation may offer more consistent absorption compared to tablets, particularly for patients who take other medications or have gastrointestinal conditions that affect absorption. It should be taken on an empty stomach, 30–60 minutes before breakfast.
13 mcg
25 mcg
50 mcg
75 mcg
88 mcg
100 mcg
112 mcg
125 mcg
137 mcg
150 mcg
175 mcg
200 mcg
13 mcg, 25 mcg, 37.5 mcg, 44 mcg, 50 mcg, 62.5 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg
Tirosint scores a 62 out of 100 on our findability scale, meaning it can be intermittently difficult to locate. As a brand-name, niche formulation of Levothyroxine in gel capsule form, Tirosint is not stocked as widely as standard Levothyroxine tablets. While it is not currently listed on the FDA drug shortage database, its specialty status means not every pharmacy carries it. Patients may need to call multiple pharmacies or use tools like Medfinder to locate it in stock nearby.
Broader Levothyroxine supply disruptions in 2024–2025 have also increased demand for alternative formulations like Tirosint, which can further strain availability at certain locations.
Tirosint can be prescribed by a variety of healthcare providers, including:
If you're having trouble finding a prescriber, Medfinder can help you locate providers in your area.
No, Tirosint is not a controlled substance. It is not scheduled by the DEA and does not have abuse potential. However, it does require a valid prescription from a licensed healthcare provider.
Most side effects of Tirosint are related to the dose being too high (overreplacement). Common side effects include:
Serious side effects that require immediate medical attention include rapid or irregular heartbeat, chest pain, shortness of breath, seizures, and signs of hyperthyroidism (excessive sweating, tremors, nervousness, insomnia, fever).
Important: Tirosint carries a boxed warning that thyroid hormones should NOT be used for weight loss. Excessive doses can cause serious or life-threatening toxicity.
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Synthroid
(Levothyroxine Sodium Tablets) — the most widely prescribed brand-name Levothyroxine tablet, available at much lower cost
Generic Levothyroxine Tablets
available from multiple manufacturers (Mylan, Sandoz, Lannett) for as low as $4–$20 for 30 tablets
Levoxyl
another brand-name Levothyroxine tablet option
Armour Thyroid
natural desiccated thyroid (porcine) containing both T4 and T3, preferred by some patients
Authorized Generic Levothyroxine Capsules
made by YARAL Pharma, a lower-cost capsule alternative to brand Tirosint
Prefer Tirosint? We can find it.
Calcium supplements
moderatereduce absorption; separate by at least 4 hours
Iron supplements
moderatereduce absorption; separate by at least 4 hours
Antacids
moderate(aluminum-containing) — reduce absorption
Proton pump inhibitors
moderate(Omeprazole, etc.) — may reduce absorption
Cholestyramine and Colestipol
moderatebind thyroid hormones; separate by 4 hours
Warfarin
moderateLevothyroxine increases anticoagulant effect; monitor INR closely
Carbamazepine, Phenytoin, Rifampin
moderateincrease thyroid hormone metabolism
Estrogen-containing contraceptives
moderatemay require Tirosint dose adjustment
Tirosint is a premium Levothyroxine formulation that offers distinct advantages for patients with absorption concerns, sensitivity to inactive ingredients, or inconsistent results with standard tablets. While its higher cost and niche market status can make it harder to find and more expensive than generic alternatives, programs like the Tirosint Copay Savings Card ($25/month) and Tirosint Direct ($65/month) can significantly reduce out-of-pocket costs.
If you're struggling to find Tirosint in stock at your local pharmacy, try using Medfinder to search for availability near you without having to call around. And always talk to your doctor before making any changes to your thyroid medication regimen.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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