Comprehensive medication guide to Roszet including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$30–$75 copay if covered; many plans require prior authorization or step therapy with generic components first.
Estimated Cash Pricing
$150–$350 per month for brand Roszet; taking generic Rosuvastatin + generic Ezetimibe separately costs just $20–$55/month.
Medfinder Findability Score
55/100
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Roszet is a combination prescription medication containing Ezetimibe and Rosuvastatin in a single tablet. It is used to treat primary hyperlipidemia (high cholesterol) and homozygous familial hypercholesterolemia (HoFH). Roszet works by reducing LDL ("bad") cholesterol, total cholesterol, triglycerides, and ApoB while increasing HDL ("good") cholesterol.
Roszet was FDA-approved in March 2021 and manufactured by Althera Life Sciences. The brand has since been discontinued, but the same active ingredients are available separately as generic Rosuvastatin (formerly Crestor) and generic Ezetimibe (formerly Zetia).
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Roszet combines two cholesterol-lowering medications with complementary mechanisms of action:
By targeting both cholesterol production and absorption simultaneously, Roszet can lower LDL cholesterol more effectively than either medication alone.
Ezetimibe 10 mg / Rosuvastatin 5 mg tablet — tablet
Ezetimibe 10 mg / Rosuvastatin 10 mg tablet — tablet
Ezetimibe 10 mg / Rosuvastatin 20 mg tablet — tablet
Ezetimibe 10 mg / Rosuvastatin 40 mg tablet — tablet
Roszet has a findability score of 55 out of 100, meaning it can be difficult to locate. The brand has been discontinued by the manufacturer (Althera Life Sciences) as of 2025, making it essentially unavailable at most pharmacies. While remaining stock may exist at some locations, supply is not being replenished. Most patients are now being switched to the individual generic components — generic Rosuvastatin and generic Ezetimibe — which are widely available and significantly cheaper.
Use Medfinder to check pharmacy availability near you, or talk to your doctor about switching to the separate generic components.
Roszet can be prescribed by a range of healthcare providers, including:
Telehealth consultations are also available for cholesterol management. Use Medfinder to find providers who can prescribe Roszet or its alternatives near you.
No, Roszet is not a controlled substance. It is not classified under any DEA schedule. It is a standard prescription medication that does not have abuse or dependence potential. You can receive Roszet prescriptions via telehealth, mail-order pharmacies, and standard refill processes without the restrictions that apply to controlled substances.
Serious side effects (seek medical attention immediately):
Contact your doctor if you experience unexplained muscle pain, tenderness, or weakness, especially with fever or dark urine.
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Generic Rosuvastatin + Generic Ezetimibe
the same active ingredients taken as two separate pills; costs $20–$55/month total
Vytorin (Ezetimibe/Simvastatin)
a similar combination tablet using a different statin
Crestor (Rosuvastatin)
+ Zetia (Ezetimibe) — brand-name versions taken separately
Lipitor (Atorvastatin)
+ Zetia (Ezetimibe) — a commonly prescribed combination using a different statin
Prefer Roszet? We can find it.
Cyclosporine
moderateincreases Rosuvastatin levels up to 7-fold
Gemfibrozil
moderatesignificantly increases statin exposure and myopathy risk
Other fibrates (Fenofibrate, Bezafibrate)
moderateincreased myopathy risk
Niacin at doses ≥1 g/day
moderateincreased myopathy risk
Colchicine
moderateincreased myopathy risk
Warfarin and other anticoagulants
moderatemay increase INR and bleeding risk
Certain HIV antivirals (Atazanavir, Darunavir, Ritonavir)
moderatedose adjustments needed
Bile acid sequestrants (Cholestyramine, Colesevelam)
moderatetake at least 2–4 hours apart
Roszet was a convenient single-tablet option for patients who needed both Ezetimibe and Rosuvastatin to manage their cholesterol. However, since the brand has been discontinued by the manufacturer, most patients will need to switch to the individual generic components — which are widely available and much more affordable at $20–$55/month combined.
If you're still looking for Roszet or need help finding an alternative, use Medfinder to search pharmacies near you or speak with your doctor about the best option for your cholesterol management.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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