Medications

Quillichew ER

Quillichew ER

Previously Found with Medfinder

Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.

Estimated Insurance Pricing
With insurance, expect to pay between $20 and $75 per fill, though coverage varies and prior authorization is often required.
Estimated Cash Pricing
Without insurance, Quillichew ER typically costs between $300 and $450 for a 30-tablet supply at retail pharmacies.
Medfinder Findability Score
45
/100
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Post Author

Peter Daggett

Last Updated

February 17, 2026

Quillichew ER 2026 Availability, Prices, and Tips to Find

What Is Quillichew ER?

Quillichew ER is a cherry-flavored, extended-release chewable tablet containing methylphenidate hydrochloride. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. Quillichew ER is designed with approximately 30% immediate-release and 70% extended-release methylphenidate, providing both rapid onset and sustained symptom control throughout the day. It is manufactured by Tris Pharma and marketed by Pfizer. Because it is a chewable tablet, Quillichew ER is particularly useful for patients who have difficulty swallowing pills.

How does Quillichew ER work?

Quillichew ER works by blocking the reuptake of norepinephrine and dopamine into presynaptic neurons in the brain. This increases the concentration of these neurotransmitters in the synaptic cleft, which helps improve attention, focus, and impulse control in patients with ADHD. The extended-release chewable formulation is taken once daily in the morning and provides symptom relief that lasts throughout the day.

What doses are available?

  • 20 mg extended-release chewable tablet (can be split into 10 mg halves)
  • 30 mg extended-release chewable tablet (can be split into 15 mg halves)
  • 40 mg extended-release chewable tablet

How hard is it to find Quillichew ER in stock?

Quillichew ER has a findability score of 45 out of 100, meaning it can be moderately difficult to locate in stock. As a Schedule II stimulant, Quillichew ER has been affected by the ongoing ADHD medication shortage driven by increased demand, DEA production quotas, and supply chain constraints. While the manufacturer Tris Pharma reports general availability, individual pharmacies may be out of stock at any given time. Using Medfinder can help you quickly identify pharmacies near you that currently have Quillichew ER in stock.

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Who Can Prescribe?

Quillichew ER can be prescribed by a variety of healthcare providers, including pediatricians, child and adolescent psychiatrists, general psychiatrists, family medicine physicians, primary care doctors, internists, and neurologists. Because it is a Schedule II controlled substance, it requires a written prescription and cannot be called in or refilled without a new prescription in most states. Telehealth providers may also prescribe Quillichew ER where permitted by state law.

Is it a controlled substance?

Yes, Quillichew ER is classified as a Schedule II (CII) controlled substance by the DEA. This means it has a high potential for abuse and dependence. Prescriptions cannot be refilled and typically require a new written prescription each month. The FDA boxed warning states that CNS stimulants, including Quillichew ER, should be assessed for abuse risk prior to prescribing, and patients should be monitored for signs of abuse and dependence during therapy.

Common Side Effects

  • Decreased appetite
  • Nausea
  • Insomnia
  • Headache
  • Abdominal pain
  • Vomiting
  • Weight loss
  • Irritability
  • Dizziness

Serious side effects may include cardiovascular events, increased blood pressure and heart rate, psychiatric symptoms, peripheral vasculopathy, long-term growth suppression, and seizures. Contact your healthcare provider immediately if you experience any serious side effects.

Alternatives

  • Concerta (Methylphenidate ER) — Extended-release tablet that is swallowed whole, using OROS technology for sustained release.
  • Ritalin LA (Methylphenidate ER) — Extended-release capsule that can be opened and sprinkled on food for patients who cannot swallow capsules.
  • Quillivant XR (Methylphenidate ER) — A liquid extended-release suspension, also made by Tris Pharma, ideal for patients who prefer a liquid form.
  • Vyvanse (Lisdexamfetamine) — An amphetamine prodrug available as a capsule or chewable tablet, offering a different stimulant mechanism.

Drug Interactions

  • MAO Inhibitors — Do not take Quillichew ER with or within 14 days of an MAOI due to the risk of hypertensive crisis.
  • Vasopressor Agents — Quillichew ER may potentiate the effects of vasopressors.
  • Blood Thinners and Anticonvulsants — Methylphenidate may inhibit the metabolism of coumarin anticoagulants, anticonvulsants, and tricyclic antidepressants, potentially increasing their blood levels.
  • Antihypertensive Medications — Quillichew ER may decrease the effectiveness of blood pressure medications.
  • Halogenated Anesthetics — Risk of sudden blood pressure increase during surgery; inform your anesthesiologist if you take Quillichew ER.

Note: Quillichew ER contains phenylalanine and should be used with caution in patients with phenylketonuria (PKU).

Final Thoughts

Quillichew ER is a valuable ADHD treatment option, especially for patients who have difficulty swallowing traditional pills. Its cherry-flavored chewable format and once-daily dosing make it convenient for children and adults alike. However, as a Schedule II controlled substance affected by the ongoing stimulant shortage, finding Quillichew ER in stock can be challenging. No generic version is currently available, which contributes to its higher cost. If you have commercial insurance, the Tris Pharma Co-pay Savings Program may reduce your out-of-pocket cost to as little as $25 per fill. Uninsured or underinsured patients may qualify for assistance through Pfizer RxPathways. Use Medfinder to locate pharmacies with Quillichew ER in stock near you.

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