Comprehensive medication guide to Quillichew ER including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
With insurance, expect to pay between $20 and $75 per fill, though coverage varies and prior authorization is often required.
Estimated Cash Pricing
Without insurance, Quillichew ER typically costs between $300 and $450 for a 30-tablet supply at retail pharmacies.
Medfinder Findability Score
45/100
On this page
Quillichew ER is a cherry-flavored, extended-release chewable tablet containing methylphenidate hydrochloride. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. Quillichew ER is designed with approximately 30% immediate-release and 70% extended-release methylphenidate, providing both rapid onset and sustained symptom control throughout the day. It is manufactured by Tris Pharma and marketed by Pfizer. Because it is a chewable tablet, Quillichew ER is particularly useful for patients who have difficulty swallowing pills.
Quillichew ER works by blocking the reuptake of norepinephrine and dopamine into presynaptic neurons in the brain. This increases the concentration of these neurotransmitters in the synaptic cleft, which helps improve attention, focus, and impulse control in patients with ADHD. The extended-release chewable formulation is taken once daily in the morning and provides symptom relief that lasts throughout the day.
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20 mg extended-release chewable tablet (can be split into 10 mg halves) — tablet
30 mg extended-release chewable tablet (can be split into 15 mg halves) — tablet
40 mg extended-release chewable tablet — tablet
Quillichew ER has a findability score of 45 out of 100, meaning it can be moderately difficult to locate in stock. As a Schedule II stimulant, Quillichew ER has been affected by the ongoing ADHD medication shortage driven by increased demand, DEA production quotas, and supply chain constraints. While the manufacturer Tris Pharma reports general availability, individual pharmacies may be out of stock at any given time. Using Medfinder can help you quickly identify pharmacies near you that currently have Quillichew ER in stock.
Quillichew ER can be prescribed by a variety of healthcare providers, including pediatricians, child and adolescent psychiatrists, general psychiatrists, family medicine physicians, primary care doctors, internists, and neurologists. Because it is a Schedule II controlled substance, it requires a written prescription and cannot be called in or refilled without a new prescription in most states. Telehealth providers may also prescribe Quillichew ER where permitted by state law.
Yes, Quillichew ER is classified as a Schedule II (CII) controlled substance by the DEA. This means it has a high potential for abuse and dependence. Prescriptions cannot be refilled and typically require a new written prescription each month. The FDA boxed warning states that CNS stimulants, including Quillichew ER, should be assessed for abuse risk prior to prescribing, and patients should be monitored for signs of abuse and dependence during therapy.
Serious side effects may include cardiovascular events, increased blood pressure and heart rate, psychiatric symptoms, peripheral vasculopathy, long-term growth suppression, and seizures. Contact your healthcare provider immediately if you experience any serious side effects.
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Concerta
(Methylphenidate ER) — Extended-release tablet that is swallowed whole, using OROS technology for sustained release.
Ritalin LA
(Methylphenidate ER) — Extended-release capsule that can be opened and sprinkled on food for patients who cannot swallow capsules.
Quillivant XR
(Methylphenidate ER) — A liquid extended-release suspension, also made by Tris Pharma, ideal for patients who prefer a liquid form.
Vyvanse
(Lisdexamfetamine) — An amphetamine prodrug available as a capsule or chewable tablet, offering a different stimulant mechanism.
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MAO Inhibitors
moderateDo not take Quillichew ER with or within 14 days of an MAOI due to the risk of hypertensive crisis.
Vasopressor Agents
moderateQuillichew ER may potentiate the effects of vasopressors.
Blood Thinners and Anticonvulsants
moderateMethylphenidate may inhibit the metabolism of coumarin anticoagulants, anticonvulsants, and tricyclic antidepressants, potentially increasing their blood levels.
Antihypertensive Medications
moderateQuillichew ER may decrease the effectiveness of blood pressure medications.
Halogenated Anesthetics
moderateRisk of sudden blood pressure increase during surgery; inform your anesthesiologist if you take Quillichew ER.
Quillichew ER is a valuable ADHD treatment option, especially for patients who have difficulty swallowing traditional pills. Its cherry-flavored chewable format and once-daily dosing make it convenient for children and adults alike. However, as a Schedule II controlled substance affected by the ongoing stimulant shortage, finding Quillichew ER in stock can be challenging. No generic version is currently available, which contributes to its higher cost. If you have commercial insurance, the Tris Pharma Co-pay Savings Program may reduce your out-of-pocket cost to as little as $25 per fill. Uninsured or underinsured patients may qualify for assistance through Pfizer RxPathways. Use Medfinder to locate pharmacies with Quillichew ER in stock near you.
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Real-time availability
Verified 39m ago
Based on 64 real pharmacy checks · 4 patients helped
Quillichew ER is in a shortage right now — Medfinder calls pharmacies near you to track down the ones that have it.
As of October 3, 2026, 8:00 PM ET, QuilliChew ER is currently experiencing a shortage. Across 64 pharmacy checks Medfinder placed in the last 30 days, QuilliChew ER was confirmed in stock 0% of the time.
QuilliChew ER is not on the FDA's active shortage list. Medfinder's own pharmacy calls put real-time availability at 0% across 64 checks in the last 30 days. Availability varies by metro, with the most pharmacy activity recorded around Brooklyn, NY. These numbers are recomputed continuously from live pharmacy calls, so this page reflects current conditions rather than a static estimate.
Is QuilliChew ER in stock right now?
As of October 3, 2026, 8:00 PM ET, QuilliChew ER was confirmed in stock at 0% of 64 pharmacies Medfinder checked in the last 30 days. Availability changes daily, so we re-check in real time when you search.
How does Medfinder help me find QuilliChew ER?
Medfinder calls pharmacies in your area to verify whether QuilliChew ER and your specific dose are in stock, then sends you the pharmacy name, address, and phone number.
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Sources: FDA Drug Shortages + Medfinder pharmacy data · Methodology · Full Quillichew ER data