Comprehensive medication guide to Lovenox including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
$10–$75 copay for generic Enoxaparin; most plans cover it as a preferred generic, though prior authorization may be required for extended outpatient use.
Estimated Cash Pricing
Generic Enoxaparin runs $30–$150 retail for a 30-day supply; as low as $25–$80 with GoodRx or SingleCare coupons. Brand Lovenox can exceed $600.
Medfinder Findability Score
65/100
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Lovenox is the brand name for Enoxaparin Sodium, a low molecular weight heparin (LMWH) anticoagulant manufactured by Sanofi-Aventis. It is an injectable blood thinner used to prevent and treat dangerous blood clots.
Lovenox is FDA-approved for:
It is also commonly used off-label as bridge therapy for patients on Warfarin undergoing surgery, for VTE prophylaxis in hospitalized medical patients, and as the preferred anticoagulant during pregnancy.
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Lovenox works by binding to and activating antithrombin III, a natural protein in your blood that helps regulate clotting. Once activated, antithrombin III primarily inhibits Factor Xa — a key enzyme in the blood clotting cascade — and to a lesser extent Factor IIa (thrombin). By blocking these clotting factors, Lovenox interrupts the coagulation process and prevents new blood clots from forming.
Unlike unfractionated Heparin, Lovenox has a more predictable dose-response relationship and longer half-life, which means it can be given as a once- or twice-daily subcutaneous injection without routine blood monitoring in most patients.
30 mg/0.3 mL prefilled syringe
40 mg/0.4 mL prefilled syringe
60 mg/0.6 mL prefilled syringe
80 mg/0.8 mL prefilled syringe
100 mg/1 mL prefilled syringe
120 mg/0.8 mL prefilled syringe
150 mg/1 mL prefilled syringe
300 mg/3 mL multi-dose vial (100 mg/mL)
Lovenox (Enoxaparin Sodium) scores a 65 out of 100 on our findability scale, meaning it can be intermittently difficult to locate. While generic Enoxaparin is widely manufactured, certain prefilled syringe strengths — particularly the 40 mg and 60 mg doses — have experienced periodic shortages since 2019 due to manufacturing disruptions at key generic producers. Brand-name Lovenox from Sanofi is generally more consistently stocked but comes at a significantly higher price. If your local pharmacy is out, try calling specialty pharmacies, hospital outpatient pharmacies, or use Medfinder to locate it in stock near you.
Lovenox is prescribed by a wide range of medical specialists, including:
No. Lovenox (Enoxaparin Sodium) is not a controlled substance and has no DEA scheduling. It does not carry a risk of abuse or dependence. However, it is a prescription-only medication that requires a doctor's order. Because it is an injectable anticoagulant with a risk of serious bleeding, it should only be used under medical supervision.
Like all anticoagulants, Lovenox carries a risk of side effects. Most are mild, but some can be serious.
Black Box Warning: Patients receiving Lovenox who undergo spinal/epidural anesthesia or spinal puncture are at risk for epidural or spinal hematomas that can result in long-term or permanent paralysis. This risk increases with indwelling epidural catheters, concomitant use of NSAIDs or antiplatelet drugs, and traumatic or repeated punctures.
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Heparin (Unfractionated)
IV or subcutaneous anticoagulant that is fully reversible with protamine; used primarily in hospital settings and requires aPTT monitoring
Fondaparinux (Arixtra)
A synthetic Factor Xa inhibitor given as a once-daily subcutaneous injection; a good option for patients with a history of heparin-induced thrombocytopenia (HIT)
Dalteparin (Fragmin)
Another low molecular weight heparin with similar efficacy to Enoxaparin; preferred in some cancer-related VTE treatment guidelines
Rivaroxaban (Xarelto)
An oral direct Factor Xa inhibitor that eliminates the need for injections; widely used for DVT/PE treatment and prevention
Apixaban (Eliquis)
Another oral Factor Xa inhibitor commonly used for DVT/PE treatment as an alternative to injectable anticoagulants
Warfarin (Coumadin)
Oral anticoagulant often used long-term after initial Enoxaparin treatment; requires regular INR monitoring
Prefer Lovenox? We can find it.
Warfarin
moderateand other oral anticoagulants
Antiplatelet agents
moderateAspirin, Clopidogrel (Plavix), Prasugrel, Ticagrelor
NSAIDs
moderateIbuprofen, Naproxen, Ketorolac (especially Ketorolac)
Thrombolytics
moderateAlteplase (tPA), Tenecteplase — significantly increases bleeding risk
Other heparins or heparinoids
moderateshould not be used together
SSRIs and SNRIs
moderate(antidepressants) — may increase bleeding tendency
Fish oil / Omega-3 supplements
moderatemay increase bleeding risk
Ginkgo biloba
moderatemay increase bleeding risk
Dipyridamole
moderateincreased hemorrhagic risk
Lovenox (Enoxaparin Sodium) remains one of the most widely prescribed injectable anticoagulants for preventing and treating blood clots. While generic Enoxaparin has made it more affordable, intermittent shortages of certain syringe strengths can make it challenging to find — particularly the 40 mg and 60 mg prefilled syringes.
If you're having trouble locating Lovenox or generic Enoxaparin at your pharmacy, Medfinder can help you search for pharmacies with it in stock near you. You can also ask your doctor about alternative strengths, multi-dose vials, or switching to a different anticoagulant if your specific dose is temporarily unavailable.
With cash prices ranging from $25–$150 for generic and $600+ for brand-name, using discount programs like GoodRx or SingleCare can lead to significant savings if you're paying out of pocket.
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