Medications

Ethyl Chloride

Ethyl Chloride

Previously Found with Medfinder

Comprehensive medication guide to {drug} including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.

Estimated Insurance Pricing
Typically included in the cost of a medical procedure or office visit; most patients do not purchase Ethyl Chloride directly.
Estimated Cash Pricing
$30–$65 per bottle or can depending on formulation; primarily purchased by healthcare facilities through medical supply distributors like McKesson.
Medfinder Findability Score
55
/100
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Post Author

Peter Daggett

Last Updated

February 14, 2026

Ethyl Chloride 2026 Availability, Prices, and Tips to Find

What Is Ethyl Chloride?

Ethyl Chloride (Chloroethane) is a vapocoolant skin refrigerant and topical anesthetic classified as an FDA-cleared prescription medical device. It is manufactured exclusively by Gebauer Company in Cleveland, Ohio, and sold under the brand name Gebauer's Ethyl Chloride.

Ethyl Chloride is used to provide temporary pain control for:

  • Injections, IV starts, and venipuncture
  • Minor surgical procedures such as lancing boils and incision and drainage of small abscesses
  • Minor sports injuries including contusions, bruises, and sprains
  • Myofascial pain management using the spray and stretch technique

It is also used off-label for trigger point therapy, cosmetic procedures like dermal filler injections, and pediatric procedural pain management.

How does Ethyl Chloride work?

When sprayed onto the skin, Ethyl Chloride rapidly evaporates, creating an immediate cooling effect on the skin surface. This rapid temperature drop decreases the initiation and conduction of impulses in surrounding sensory nerves, temporarily numbing the area and providing short-term pain relief lasting approximately 60 seconds per application.

For the spray and stretch technique used in myofascial pain management, the product is sprayed from 12–18 inches away in parallel sweeps over the affected muscle while the muscle is passively stretched.

What doses are available for Ethyl Chloride?

Ethyl Chloride is available in several spray formulations from Gebauer Company:

  • Fine Stream Spray Bottle — 3.5 oz (100 mL) amber glass bottle
  • Medium Stream Spray Bottle — 3.5 oz (100 mL) amber glass bottle
  • Mist Spray Can — 3.9 oz aerosol can
  • Accustream 360 Fine Stream Can
  • Accustream 360 Medium Stream Can

The typical application is a spray of 3–7 seconds (bottle) or 4–10 seconds (aerosol can) from a distance of 3–9 inches until the skin just turns white. No generic version is currently available.

How hard is it to find Ethyl Chloride in stock?

Ethyl Chloride scores a 55 out of 100 on our findability scale, meaning it can be intermittently difficult to find. As a single-source product manufactured exclusively by Gebauer Company, any production delays or raw material issues can lead to temporary supply constraints. There is no active FDA shortage as of early 2025, but individual facilities may experience periodic availability gaps. Because this is classified as an FDA-cleared medical device rather than a traditional drug, it is typically stocked by medical supply distributors rather than retail pharmacies — making it harder for patients to locate on their own.

Use Medfinder to check real-time availability and find Ethyl Chloride near you.

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Who Can Prescribe Ethyl Chloride?

Ethyl Chloride is typically used in clinical settings by a variety of healthcare professionals, including:

  • Emergency Medicine physicians — for IV starts and minor procedures
  • Sports Medicine doctors — for acute sports injuries
  • Dermatologists — for minor skin procedures
  • Pain Management specialists — for trigger point therapy
  • Physical Therapists / Rehabilitation specialists — for spray and stretch technique
  • Pediatricians — for reducing procedural pain in children
  • Family Medicine physicians — for general office procedures
  • Orthopedic Surgeons and Plastic Surgeons

Since Ethyl Chloride is primarily used in-office by providers, patients typically do not need to obtain it themselves. Telehealth is generally not applicable for this product.

Is Ethyl Chloride a controlled substance?

No, Ethyl Chloride is not a DEA-scheduled controlled substance. It is classified as an FDA-cleared prescription medical device (not a drug). However, it carries important safety warnings: it is highly flammable and must never be used near open flames or electrical cautery equipment. Additionally, intentional misuse by inhaling concentrated vapors can cause serious harm or death.

Common Side Effects of Ethyl Chloride

  • Temporary skin whitening at the application site
  • Brief stinging or burning sensation
  • Cutaneous sensitization (extremely rare)

Serious Side Effects (Seek Medical Attention)

  • Frostbite from over-application
  • Altered skin pigmentation
  • Tissue damage if sprayed too long
  • Fire or burns if used near open flame or cautery equipment
  • Allergic reaction (rash, itching, swelling)

Ethyl Chloride should only be applied by a trained healthcare professional to minimize the risk of side effects.

Alternative Medications to Ethyl Chloride

If Ethyl Chloride is unavailable or unsuitable, several alternatives exist:

  • Gebauer's Pain Ease — A non-flammable vapocoolant spray by the same manufacturer. Can be used on intact skin, minor open wounds, and oral mucous membranes. Non-prescription.
  • Gebauer's Spray and Stretch — A non-flammable vapocoolant designed specifically for myofascial pain management and trigger point therapy.
  • EMLA Cream (Lidocaine/Prilocaine) — A topical anesthetic cream that numbs the skin. Requires 30–60 minutes to take effect but provides longer-lasting numbing.
  • CoolJect — A non-ethyl chloride, non-flammable, hazmat-free vapocoolant alternative for needle procedures.

Talk to your healthcare provider about which alternative may work best for your situation.

Drug Interactions with Ethyl Chloride

Ethyl Chloride has no known major drug interactions. Because it is a topical vapocoolant that works through localized skin cooling rather than systemic absorption, it does not interact with oral medications, injectables, or other topical products in a clinically significant way.

However, patients should inform their healthcare provider about all medications they are taking, particularly other topical anesthetics being used in the same area, to avoid excessive skin numbing or tissue damage.

Important safety note: Ethyl Chloride is highly flammable. It must never be used near open flames, electrical cautery equipment, or other ignition sources during procedures.

Final Thoughts on Ethyl Chloride

Ethyl Chloride is a niche but important medical device used by healthcare professionals for fast-acting topical pain control. As a single-source product from Gebauer Company, it can occasionally be difficult to find when supply chain issues arise. With a findability score of 55, patients and providers may encounter intermittent availability challenges.

If you're a healthcare provider struggling to stock Ethyl Chloride, consider reaching out to medical supply distributors like McKesson or McGuff, or explore non-flammable alternatives like Gebauer's Pain Ease. Patients undergoing procedures can ask their provider about which vapocoolant will be used.

Use Medfinder to track availability and find Ethyl Chloride in stock near you.

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