Comprehensive medication guide to Ciclesonide including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
With insurance, most patients pay $15–$75 for Ciclesonide, though prior authorization may be required.
Estimated Cash Pricing
Without insurance, Ciclesonide costs between $150 and $420 depending on the formulation and pharmacy.
Medfinder Findability Score
55/100
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Ciclesonide is an inhaled corticosteroid used to treat persistent asthma and allergic rhinitis. It is sold under three brand names: Alvesco (oral inhaler for asthma), Omnaris (nasal spray for allergic rhinitis), and Zetonna (nasal aerosol for seasonal allergic rhinitis).
Alvesco is approved for maintenance treatment of asthma in adults and children 12 years and older. Omnaris is approved for seasonal and perennial allergic rhinitis in patients 6 years and older. Zetonna is approved for seasonal allergic rhinitis in patients 12 and older.
Ciclesonide is a maintenance medication — it is taken daily to prevent symptoms and is not intended for acute asthma attacks or sudden allergy flare-ups.
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Ciclesonide is a prodrug, meaning it becomes active only after reaching the lungs or nasal passages. Once inhaled, enzymes convert it into its active form called des-ciclesonide, which has 120 times greater affinity for the glucocorticoid receptor than the parent compound.
Des-ciclesonide works by suppressing inflammation — it reduces the release of inflammatory chemicals and inhibits immune cell activity in the airways and nasal tissues. This decreases swelling, mucus production, and irritation, helping to control asthma symptoms and relieve nasal congestion, sneezing, and runny nose from allergies.
Because Ciclesonide is activated locally rather than systemically, it may cause fewer systemic side effects compared to some other inhaled corticosteroids.
Alvesco (oral inhaler) — inhaler
80 mcg/actuation and 160 mcg/actuation metered-dose inhalers
Omnaris (nasal spray) — spray
50 mcg/spray (120 sprays per bottle)
Zetonna (nasal aerosol)
37 mcg/spray (limited availability)
Ciclesonide scores a 55 out of 100 on our findability scale, meaning it can be moderately difficult to locate. Because Ciclesonide is a single-source brand product with no generic competition, supply depends entirely on Covis Pharma's manufacturing capacity. While Ciclesonide is not currently on the FDA drug shortage list, periodic supply disruptions have been reported at individual pharmacies. If your usual pharmacy is out of stock, try checking specialty or mail-order pharmacies, or use Medfinder to locate it nearby.
Several types of healthcare providers can prescribe Ciclesonide:
Telehealth prescribing is also available for Ciclesonide, making it accessible for patients who cannot visit a clinic in person.
No. Ciclesonide is not a controlled substance and does not have a DEA schedule. It is a prescription-only corticosteroid with no known abuse potential. You will still need a valid prescription from a licensed healthcare provider to purchase it.
Most side effects are mild and improve with continued use. With the inhaler formulation, rinse your mouth after each use to reduce the risk of oral thrush (candidiasis). Serious side effects are rare but may include adrenal suppression, immunosuppression, glaucoma, cataracts, and growth suppression in children with long-term use. Contact your doctor if you experience vision changes, signs of infection, or worsening breathing.
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Fluticasone Propionate (Flovent inhaler / Flonase nasal spray)
widely available, Flonase is available over the counter for allergic rhinitis. Generic versions exist.
Budesonide (Pulmicort inhaler / Rhinocort nasal spray)
available as generic, Rhinocort is OTC. Also available as a nebulizer solution.
Mometasone Furoate (Asmanex inhaler / Nasonex nasal spray)
Nasonex is now available OTC. Highly effective for allergic rhinitis.
Beclomethasone Dipropionate (QVAR inhaler / Beconase AQ nasal spray)
older corticosteroid, widely available as generic.
Prefer Ciclesonide? We can find it.
Ketoconazole
moderateincreases des-ciclesonide exposure by approximately 3.6-fold. Avoid concurrent use if possible.
Other strong CYP3A4 inhibitors:
moderateItraconazole, Voriconazole, Clarithromycin, Ritonavir, Nelfinavir, Cobicistat
Moderate CYP3A4 inhibitors:
moderateErythromycin, Fluconazole, Diltiazem, Verapamil
HIV protease inhibitors:
moderateAtazanavir, Indinavir, Saquinavir
Other corticosteroids
moderateconcurrent use increases risk of adrenal suppression
Ciclesonide is an effective inhaled corticosteroid for managing persistent asthma and allergic rhinitis. Its unique prodrug design means it's activated locally, which may result in fewer systemic side effects. However, as a brand-only medication with no generic available, it can be expensive without insurance — ranging from $150 to $420 depending on the formulation.
If you have commercial insurance, the Alvesco Savings Card from Covis Pharma may reduce your out-of-pocket cost to as little as $0. Uninsured patients should check the Covis Patient Assistance Program at alvesco.us for eligibility.
If your pharmacy is out of stock, use Medfinder to search nearby pharmacies or consider asking your doctor about widely available alternatives like Fluticasone or Budesonide.
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