Comprehensive medication guide to Aminocaproic Acid including estimated pricing, availability information, side effects, and how to find it in stock at your local pharmacy.
Estimated Insurance Pricing
With insurance, most patients pay $10–$50 for generic Aminocaproic Acid, as it is covered by most commercial plans and Medicare Part D.
Estimated Cash Pricing
Without insurance, Aminocaproic Acid tablets typically cost $290–$650 at retail, but discount coupons can bring the price as low as $32–$36.
Medfinder Findability Score
45/100
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Aminocaproic Acid (also known by the brand name Amicar) is an antifibrinolytic hemostatic agent used to treat and prevent excessive bleeding caused by hyperfibrinolysis — a condition where the body breaks down blood clots too quickly. It is FDA-approved for acute bleeding syndromes due to elevated fibrinolytic activity, including hemorrhagic complications following cardiac surgery, bleeding associated with hematological disorders, hepatic cirrhosis, and neoplastic disease.
It is also used off-label for prevention of dental bleeding in hemophilia patients, prophylaxis of rebleeding after subarachnoid hemorrhage, traumatic hyphema, hereditary angioedema, heavy menstrual bleeding, and management of radiation cystitis.
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Aminocaproic Acid is a lysine analog that works by competitively binding to the kringle domain of plasminogen, blocking its binding to fibrin and its activation to plasmin. By inhibiting plasminogen activators and, to a lesser degree, plasmin activity directly, it prevents fibrin degradation (fibrinolysis) and helps stabilize blood clots. This mechanism effectively reduces excessive bleeding by keeping clots intact longer.
500 mg oral tablet — tablet
most widely available oral form
1000 mg oral tablet — tablet
limited availability (Akorn discontinued)
250 mg/mL oral solution — solution
available from generic manufacturers
250 mg/mL intravenous injection (20 mL vials) — injection
used in clinical settings, subject to periodic shortages
Aminocaproic Acid has a findability score of 45 out of 100, meaning it can be moderately difficult to locate in stock. The injectable (IV) formulation has experienced periodic shortages due to Pfizer manufacturing delays, and Akorn's discontinuation of the 1000 mg oral tablet has reduced supplier options. The 500 mg tablet and oral solution remain available from generic manufacturers, but supply can be inconsistent depending on your region. Using Medfinder can help you quickly check which pharmacies near you currently have it in stock.
Aminocaproic Acid is most commonly prescribed by specialists, including:
Any licensed physician, nurse practitioner, or physician assistant can prescribe it, but it is most often initiated by the specialties above.
No, Aminocaproic Acid is not a controlled substance. It has no DEA scheduling and does not carry abuse or dependence potential. It can be prescribed and dispensed like any standard prescription medication without the restrictions that apply to controlled substances.
Serious side effects (seek immediate medical attention):
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Tranexamic Acid (Lysteda, Cyklokapron)
Another lysine-analog antifibrinolytic that is approximately 10 times more potent than Aminocaproic Acid. Available as oral tablets, IV injection, and topical formulations. Widely used for heavy menstrual bleeding, surgical bleeding, and trauma.
Desmopressin (DDAVP, Stimate)
A synthetic vasopressin analog that stimulates release of von Willebrand factor and factor VIII. Used for mild hemophilia A and von Willebrand disease. Available as nasal spray, IV, and subcutaneous injection.
Aprotinin (Trasylol)
A natural serine protease inhibitor used to reduce bleeding during cardiac surgery. Reintroduced with restricted use after being temporarily withdrawn for safety concerns.
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Factor IX complex concentrates and anti-inhibitor coagulant concentrates
moderateSignificantly increased risk of thrombosis when combined
Estrogens and hormonal contraceptives
moderateIncreased thrombotic risk
Tretinoin (all-trans retinoic acid)
moderateIncreased thrombotic risk
Defibrotide
moderateAminocaproic Acid decreases its effects by pharmacodynamic antagonism
Thrombolytic agents (Alteplase, Reteplase, Tenecteplase)
moderateAminocaproic Acid counteracts their clot-dissolving effects
Aminocaproic Acid is a vital antifibrinolytic medication for patients dealing with excessive bleeding conditions, but finding it in stock can be challenging due to periodic shortages — particularly the IV formulation and the 1000 mg tablet. With a findability score of 45, patients may need to check multiple pharmacies. Discount coupons from GoodRx or SingleCare can bring the cash price down to as low as $32–$36 for oral tablets. If you're having trouble locating Aminocaproic Acid, Medfinder can help you search nearby pharmacies for real-time availability.
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Our medication guides are researched and written to help patients make informed decisions. All content is reviewed for accuracy and updated regularly. Learn more about our standards
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