Ganirelix is a GnRH antagonist injection used in IVF to prevent premature ovulation. Learn about uses, dosage, cost, side effects, and more for 2026.
If your fertility doctor has mentioned Ganirelix as part of your IVF protocol, you probably have questions. What does it do? How do you take it? How much does it cost? This guide covers everything you need to know about Ganirelix in 2026 — in plain language.
Ganirelix (generic name: Ganirelix Acetate) is an injectable medication classified as a GnRH antagonist — a gonadotropin-releasing hormone antagonist. It works by blocking a hormone signal in your brain that would otherwise trigger ovulation too early during an IVF cycle.
Ganirelix was originally approved by the FDA under the brand name Antagon, manufactured by Organon. Other brand names include Fyremadel and Orgalutran (used outside the U.S.). A generic version is manufactured by Amphastar Pharmaceuticals.
Ganirelix is not a controlled substance and does not have a DEA schedule.
Ganirelix has one primary FDA-approved use:
During an IVF cycle, your doctor gives you medications (like FSH injections) to stimulate your ovaries to produce multiple eggs. Without Ganirelix, your body might release a surge of luteinizing hormone (LH) too early, causing you to ovulate before the eggs can be retrieved. Ganirelix stops that from happening.
For a detailed explanation of how this works, see our guide on how Ganirelix works.
Some off-label uses include managing endometriosis and, rarely, precocious puberty — but these are uncommon and not the primary reason Ganirelix is prescribed.
Ganirelix comes as a prefilled syringe containing 250 mcg in 0.5 mL of solution. It's given as a subcutaneous injection — meaning you inject it just under the skin, not into a muscle.
Ganirelix is contraindicated in the following situations:
Ganirelix should only be prescribed by physicians experienced in infertility treatment. It is not indicated for use in men, children, or elderly patients.
For information on side effects, read our detailed guide on Ganirelix side effects.
The cost of Ganirelix varies depending on whether you're paying retail, using insurance, or using a discount coupon:
Coverage for Ganirelix varies significantly. Many insurance plans do not cover fertility medications at all. In states with fertility treatment mandates (like Massachusetts, Illinois, Connecticut, and others), your plan may be required to cover IVF drugs including Ganirelix. Prior authorization is typically required even when covered.
If you're uninsured or struggling with costs, several programs can help:
For a complete breakdown, see our guide on how to save money on Ganirelix.
Ganirelix is a well-established fertility medication that plays a critical role in IVF cycles by preventing premature ovulation. It's given as a simple daily injection for a few days during your stimulation phase. While the cost can be significant — especially without insurance — discount coupons and patient assistance programs can bring the price down considerably.
If you need help finding Ganirelix in stock near you, Medfinder can show you which pharmacies have it available right now. And for more IVF medication guides, explore our articles on Ganirelix alternatives and drug interactions.
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