What Is Adderall XR?

Adderall XR is a prescription extended-release capsule containing a combination of amphetamine and dextroamphetamine, used to treat attention-deficit/hyperactivity disorder (ADHD) in patients aged 6 and older.

It belongs to a class of drugs called central nervous system (CNS) stimulants. The "XR" stands for extended-release, which means the medication is designed to release its active ingredients gradually throughout the day, so you only need to take it once in the morning.

Key Facts at a Glance

• Generic name: Amphetamine/dextroamphetamine extended-release (also called mixed amphetamine salts XR or amphetamine salt combo XR)
• Brand name: Adderall XR
• Drug class: CNS stimulant (amphetamine)
• Original manufacturer: Shire (now Takeda). Generic versions are made by Teva, Sandoz, and other manufacturers.
• FDA approval: Approved for ADHD treatment
• DEA schedule: Schedule II controlled substance (CII) — meaning it has a high potential for abuse and requires a new prescription each month
• Generic available: Yes

What Is Adderall XR Used For?

FDA-Approved Uses

Adderall XR is FDA-approved for one indication:

• ADHD (Attention-Deficit/Hyperactivity Disorder) — in patients aged 6 and older, including children, adolescents, and adults

Note: The immediate-release version (Adderall IR) is also approved for narcolepsy, but Adderall XR is specifically approved only for ADHD.

Off-Label Uses

Some doctors prescribe Adderall XR off-label for conditions such as:

• Treatment-resistant depression
• Binge eating disorder
• Excessive daytime sleepiness

Off-label use means the medication hasn't been FDA-approved for that specific condition, but a doctor may still prescribe it based on clinical judgment and evidence.

How Is Adderall XR Taken?

Adderall XR is taken once daily in the morning, with or without food. Here's what you need to know:

• Swallow the capsule whole — do not crush or chew the beads inside
• Alternative method: If you have difficulty swallowing capsules, you can open the capsule and sprinkle the entire contents on a spoonful of applesauce. Swallow immediately without chewing.
• Avoid afternoon or evening doses — taking it too late in the day can cause insomnia
• Take it at the same time each day for the best results

Dosage

Adderall XR comes in the following strengths: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg extended-release capsules.

Typical starting doses:

• Children (ages 6–12): 10 mg once daily in the morning
• Adolescents (ages 13–17): 10 mg once daily in the morning
• Adults: 20 mg once daily in the morning

Your doctor may adjust your dose in 5 mg or 10 mg increments based on how you respond. The maximum recommended dose is 30 mg per day.

Never change your dose without talking to your doctor first.

Who Should Not Take Adderall XR?

Adderall XR is not safe for everyone. You should not take it if you have:

• A known allergy to amphetamine products
• Advanced arteriosclerosis (hardening of the arteries)
• Symptomatic cardiovascular disease, including heart failure or recent heart attack
• Moderate to severe high blood pressure
• Hyperthyroidism (overactive thyroid)
• Glaucoma
• A history of drug abuse
• Agitated states (severe anxiety or agitation)

Adderall XR is also contraindicated if you've taken an MAO inhibitor within the last 14 days. Combining these medications can cause a dangerous spike in blood pressure (hypertensive crisis).

Pregnancy: Adderall XR is not recommended during pregnancy. It may cause premature birth, low birth weight, and withdrawal symptoms in newborns. Talk to your doctor about safer alternatives if you're pregnant or planning to become pregnant.

For a complete list of medications that interact with Adderall XR, see our guide on Adderall XR drug interactions.

How Much Does Adderall XR Cost?

The cost of Adderall XR depends on whether you're getting the brand name or generic, and whether you have insurance:

• Brand-name Adderall XR: $200–$350 for 30 capsules (without insurance)
• Generic (amphetamine salt combo XR): $220–$350 retail price, but as low as $17–$26 with a GoodRx coupon for 30 capsules
• With insurance: Generic Adderall XR is widely covered by most plans as a Tier 2 preferred generic. Your copay will depend on your plan.

If cost is a concern, check out our full guide on how to save money on Adderall XR, including coupon cards, patient assistance programs, and other options.

Insurance Tips

Brand-name Adderall XR may require prior authorization or step therapy (meaning your insurance wants you to try the generic first). Most patients can use the generic version without any issue — it contains the same active ingredients in the same amounts.

Adderall XR vs. Adderall IR

You may be wondering about the difference between Adderall XR and regular Adderall (IR):

• Adderall XR (extended-release): Taken once daily. Lasts approximately 10–12 hours. Uses a two-bead system to release medication in two phases.
• Adderall IR (immediate-release): Taken 2–3 times per day. Each dose lasts about 4–6 hours.

For more on how the extended-release mechanism works, see how Adderall XR works.

Current Availability

As of early 2026, Adderall XR remains affected by an ongoing national shortage. The 15 mg, 25 mg, and 30 mg strengths are particularly hard to find. If you're having trouble filling your prescription, Medfinder can help you find a pharmacy with stock near you.

Final Thoughts

Adderall XR is a well-established, effective treatment for ADHD that offers the convenience of once-daily dosing. Understanding how it works, how to take it, and what to watch out for puts you in the best position to benefit from your treatment.

If you're experiencing side effects or have questions about your dose, talk to your prescriber. And if you need help finding Adderall XR in stock, visit Medfinder to search pharmacies near you.