Zilxi can cost $400-$600 without insurance. Learn how to save with coupons, the Zilxi Savings Card, discount programs, and patient assistance in 2026.
Zilxi (Minocycline topical foam, 1.5%) is an effective treatment for the pimples and bumps of rosacea — but it comes with a hefty price tag. Without insurance, a single 60g canister can cost between $400 and $600. Even with insurance, copays for this specialty medication can run high.
The good news? There are several ways to bring that cost down significantly. In this guide, we'll walk through every option for saving money on Zilxi in 2026, from manufacturer coupons to patient assistance programs.
Here's what you can expect to pay for Zilxi without insurance or discount programs:
Because there's no generic version of Zilxi available as of 2026, you can't save money by switching to a generic equivalent. The brand-name product is the only option.
If you have commercial health insurance, the Zilxi Savings Card from Journey Medical Corporation is the single best way to lower your out-of-pocket cost. Here's how it works:
Who qualifies: Patients with private/commercial insurance. This includes employer-sponsored plans and plans purchased through the ACA marketplace (in most cases).
Who doesn't qualify: Patients with government insurance — Medicare, Medicaid, Tricare, or VA coverage. Patients without any insurance may also have limited eligibility for the savings card but should call to confirm.
If you don't qualify for the manufacturer savings card or you're uninsured, pharmacy discount cards can help reduce the cash price:
GoodRx typically offers Zilxi for around $401-$480 at participating pharmacies, which is a savings of roughly 20-33% off the average retail price. Simply search for Zilxi on GoodRx, select your pharmacy, and show the coupon at pickup.
SingleCare is another popular discount card that may offer competitive pricing on Zilxi. Check SingleCare for current prices at pharmacies near you.
Additional coupon card options to check include:
Prices can vary significantly between pharmacies, so it's worth comparing a few options before filling your prescription.
If you're uninsured, underinsured, or facing financial hardship, patient assistance programs (PAPs) may provide Zilxi at little or no cost:
The manufacturer may offer assistance for patients who cannot afford Zilxi. Contact them directly:
Be prepared to provide information about your income, insurance status, and prescription details.
NeedyMeds is a nonprofit that maintains a database of patient assistance programs, discount cards, and other resources. Search for "Zilxi" or "Minocycline" to find current programs you may qualify for.
RxAssist is another comprehensive database of pharmaceutical manufacturer assistance programs. It can help you identify programs you may not have known about.
RxHope connects patients with manufacturer-sponsored assistance programs and can help you navigate the application process.
If your insurance denied coverage for Zilxi, you have the right to appeal. Your dermatologist can help by submitting a letter of medical necessity explaining why Zilxi is the best treatment for your rosacea after other options have failed. Many denials are overturned on appeal.
Your dermatologist's office may have Zilxi samples provided by the manufacturer's sales representatives. While samples won't solve the long-term cost issue, they can provide a free supply for a few weeks while you work on other cost-saving strategies.
If the cost of Zilxi is simply too high, talk to your dermatologist about more affordable alternatives. Treatments like generic Metronidazole gel ($20-$50 with a coupon), generic Azelaic Acid 15% gel ($30-$80), or generic Doxycycline (under $20) can be effective options at a fraction of the price. See our full comparison: alternatives to Zilxi.
Some states offer pharmaceutical assistance programs for residents who meet certain income criteria. Check with your state's department of health or human services to see if you qualify.
Prices for the same medication can vary by $100 or more between pharmacies. Use Medfinder not just to find stock, but to compare pricing at different pharmacies near you.
Here's a summary of what you might pay for Zilxi depending on your situation:
Zilxi doesn't have to break the bank. The Zilxi Savings Card is the best deal for commercially insured patients, potentially dropping your cost to just $25 per prescription. For uninsured patients, discount cards like GoodRx can save 20-33%, and patient assistance programs may provide the medication at no cost.
Start by signing up for the savings card at zilxi.com, then use Medfinder to find a pharmacy with Zilxi in stock at the best price.
For help finding the medication, read our guide on how to find Zilxi in stock near you. And if you're looking for a prescriber, check out how to find a doctor who can prescribe Zilxi.
You focus on staying healthy. We'll handle the rest.
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