Azelastine Doesn't Have to Break the Bank

If you've been prescribed Azelastine for your allergies, you might be wondering what it's going to cost — especially if your insurance doesn't cover it or you're paying cash. The good news is that Azelastine is one of the more affordable allergy medications, particularly in its generic and OTC forms.

But prices vary widely depending on the formulation, where you buy it, and whether you use discount tools. In this guide, we'll break down exactly what Azelastine costs in 2026 and show you every way to save.

What Does Azelastine Cost Without Insurance?

Here's what you can expect to pay at the pharmacy counter without insurance in 2026:

OTC Astepro (Azelastine 0.15%)

• Price: $15 to $22 per bottle
• Supply: About 30 days (200 sprays)
• No prescription needed

This is the most affordable option for most allergy sufferers. Since Astepro went over the counter in 2022, you can buy it off the shelf at any major pharmacy or retailer.

Generic Azelastine Nasal Spray (Prescription, 0.1%)

• Cash price: $25 to $80 without any discounts
• With a discount card: $15 to $45
• Supply: 30 days

The prescription version is still available and may be preferred for certain conditions like vasomotor rhinitis. The cash price varies significantly by pharmacy, so it pays to shop around.

Dymista (Azelastine + Fluticasone Combination)

• Cash price: $180 to $350 per bottle
• With manufacturer copay card: $0 to $30 per month (commercially insured patients)
• Supply: 30 days

Dymista is the most expensive Azelastine option because it's still a brand-name product combining two active ingredients. If your doctor prescribes Dymista, saving strategies are especially important.

Azelastine Ophthalmic Solution (Eye Drops)

• Cash price: $15 to $80
• Generic available
• Supply: 30 days

Coupons and Discount Cards

Prescription discount cards are one of the easiest ways to reduce your Azelastine cost. These are free to use and accepted at most pharmacies. Here are the best options:

GoodRx

GoodRx is one of the most popular prescription discount services. For generic Azelastine nasal spray, GoodRx coupons can bring the price down to $15 to $30 at major pharmacies. Simply search for "Azelastine" on GoodRx.com, compare prices at nearby pharmacies, and show the coupon at the counter.

SingleCare

SingleCare offers similar discounts to GoodRx. Prices for generic Azelastine typically range from $15 to $35 with a SingleCare card. You can get a free card at singlecare.com.

RxSaver

RxSaver compares prices across multiple discount programs to find you the lowest price. For Azelastine, prices often come in at $15 to $40 depending on your pharmacy.

Other Discount Cards

Several other services offer competitive pricing on Azelastine:

• Optum Perks: Discounts at over 64,000 pharmacies
• BuzzRx: Free discount card with prices comparable to GoodRx
• ScriptSave WellRx: Accepted at most major chains
• America's Pharmacy: Often has competitive pricing on generics

Pro tip: Prices vary between discount cards and between pharmacies. Always compare at least 2-3 services before filling your prescription. The same medication can cost $15 at one pharmacy and $45 at another — even in the same neighborhood.

Patient Assistance Programs

If you're uninsured or underinsured and struggling to afford your medication, patient assistance programs (PAPs) may help:

Viatris Patient Assistance Program

Viatris (the manufacturer of Dymista) offers a patient assistance program for eligible patients who cannot afford their medication. If you qualify, you may receive Dymista at no cost. Eligibility is typically based on income (usually at or below 200-300% of the federal poverty level) and lack of prescription drug coverage.

Apply at viatris.com or call their patient assistance line.

Dymista Copay Card

If you have commercial insurance (not Medicare or Medicaid), the Dymista copay card can reduce your out-of-pocket cost to as low as $0 to $30 per month. Visit dymista.com to enroll or ask your doctor's office for a card.

NeedyMeds

NeedyMeds.org is a nonprofit that maintains a database of patient assistance programs, discount drug cards, and other resources. Search for "Azelastine" to find all available programs. They also offer their own discount card.

RxAssist

RxAssist.org is another comprehensive database of patient assistance programs. It's run by Volunteers in Health Care and can help you find programs based on your specific medication and financial situation.

Other Ways to Save on Azelastine

Buy OTC When Possible

If your doctor agrees that OTC Astepro is appropriate for your condition, buying it off the shelf is often the cheapest option at $15 to $22 — less than most prescription copays. No prescription, no pharmacy wait, no insurance hassle.

Use Mail-Order Pharmacies

Mail-order pharmacies often offer lower prices than retail pharmacies, especially for 90-day supplies:

• Cost Plus Drugs: Mark Cuban's pharmacy offers transparent, low-cost pricing on generics
• Amazon Pharmacy: Prime members get additional discounts on generic medications
• Your insurance mail-order option: Many plans offer 90-day supplies for the price of a 60-day copay through their preferred mail-order pharmacy

Ask for a 90-Day Supply

If you use Azelastine regularly, ask your doctor to prescribe a 90-day supply. Most pharmacies and insurance plans offer a per-unit discount for larger quantities. You'll save money and avoid monthly refill trips.

Compare Pharmacy Prices

Prices for the same generic medication can vary dramatically between pharmacies. Here's a general guide:

• Costco and Walmart tend to have the lowest cash prices on generics
• Independent pharmacies may match or beat chain prices if you ask
• CVS and Walgreens often have higher list prices but may match discount card prices

Use Separate Sprays Instead of Dymista

If your doctor has prescribed Dymista (Azelastine + Fluticasone), you can potentially save a lot by using the two ingredients separately:

• OTC Astepro (Azelastine): ~$18
• OTC Flonase (Fluticasone): ~$15
• Total: ~$33 vs. $180-$350 for Dymista

The convenience of one spray vs. two is the trade-off, but the savings can be substantial. Talk to your doctor about whether this approach works for you.

Check for Store-Brand Versions

Some retailers offer store-brand versions of OTC Astepro at lower prices. Check the allergy aisle at Walmart, Target, and Costco for generic versions of Azelastine 0.15% nasal spray.

What About Insurance?

If you have insurance, here's what to expect:

• Generic Azelastine 0.1%: Usually covered on Tier 2 (preferred generic) with a copay of $5 to $25
• Azelastine 0.15% (prescription): May no longer be covered since OTC Astepro became available
• Dymista: Often requires prior authorization and/or step therapy; copay varies widely ($30 to $75 with coverage)
• OTC Astepro: Typically not covered by insurance

If your insurance denies coverage for a prescription Azelastine product, ask your doctor to submit a prior authorization explaining the medical necessity. This is especially important for vasomotor rhinitis, where the prescription is clinically appropriate.

For more information about Azelastine, including side effects to watch for and drug interactions, explore our other guides.

Final Thoughts

Azelastine is an effective allergy medication that doesn't have to be expensive. For most patients, the OTC Astepro option at $15 to $22 is the most affordable path. If you need prescription Azelastine, discount cards can bring generic prices down to $15 to $45. And if you're prescribed Dymista, manufacturer copay cards and patient assistance programs can dramatically reduce or eliminate your cost.

The key is to compare prices, use discount tools, and talk to your doctor about the most cost-effective formulation for your needs. And if you're having trouble finding Azelastine at your pharmacy, use Medfinder to check stock near you.