Adalimumab can cost up to $11,000/month without insurance. Learn how to save with biosimilars, copay cards, discount programs, and patient assistance.
Adalimumab (brand name Humira) is one of the most widely prescribed biologic medications in the world, treating conditions like rheumatoid arthritis, Crohn's disease, psoriasis, and more. It's also one of the most expensive. Without insurance, brand-name Humira can cost $7,000 to $11,000 per month.
The good news: you don't have to pay full price. Between biosimilars, manufacturer savings programs, discount cards, and patient assistance programs, most patients can significantly reduce what they pay for adalimumab. Here's how.
Here's what you can expect to pay in 2026 without any insurance or discount:
Even the lowest-priced biosimilar options cost over $15,000 per year — a significant expense for anyone paying out of pocket. That's why it's critical to explore every savings opportunity available to you.
The single biggest way to reduce your adalimumab cost is to use a lower-priced biosimilar instead of brand-name Humira. Since 2023, more than 10 adalimumab biosimilars have entered the U.S. market. They contain the same active drug and work the same way — the FDA requires them to be just as safe and effective as the original.
The cheapest options are unbranded biosimilars, which have lower list prices because they don't carry the same rebate structure as branded products:
Ask your doctor if switching to a lower-cost biosimilar is right for you. Several biosimilars — including Amjevita, Cyltezo, Hadlima, Hyrimoz, Hulio, Simlandi, and Yuflyma — are FDA-designated as interchangeable, meaning your pharmacist may be able to make the switch without a new prescription.
Learn more: Alternatives to Adalimumab If You Can't Fill Your Prescription
If you have commercial insurance, manufacturer copay programs can dramatically reduce your out-of-pocket costs:
AbbVie's copay assistance program for Humira can reduce your monthly cost to as low as $5 per month for eligible commercially insured patients. The program covers the difference between your copay and $5, up to a maximum annual benefit. You can enroll at humira.com or by calling 1-800-4HUMIRA.
Eligibility: Must have commercial insurance. Not available for patients with Medicare, Medicaid, TRICARE, or other government insurance.
Most biosimilar manufacturers offer their own copay assistance:
These programs vary in benefit amounts. Contact the manufacturer of your specific biosimilar to learn about available savings.
If you're uninsured, underinsured, or experiencing financial hardship, patient assistance programs (PAPs) may provide adalimumab at no cost:
AbbVie provides Humira at no cost to eligible patients who are uninsured or underinsured and meet income guidelines. Apply online at abbvie.com or call 1-800-222-6885.
If you're paying cash (no insurance), discount cards from services like GoodRx, SingleCare, or RxSaver may offer reduced pricing at certain pharmacies. For brand Humira, GoodRx coupons can bring the price down to approximately $7,090 (from the ~$11,000 retail price). For biosimilars, discounts vary by pharmacy.
Note: Discount cards cannot be combined with insurance. They're best for uninsured patients or when insurance doesn't cover the specific product.
If you're waiting for insurance approval or switching medications, ask your doctor if they have sample pens or syringes available. Manufacturers supply samples to prescriber offices, and a sample can bridge the gap so you don't miss a dose.
Some employers have specialty drug carve-out programs or partnerships with organizations that negotiate lower prices for high-cost biologics. Check with your HR or benefits department.
Some states offer pharmaceutical assistance programs for residents who meet income requirements. These programs may cover or subsidize the cost of biologics like adalimumab. Contact your state health department or search on needymeds.org for state-specific options.
Nobody should go without adalimumab because of cost. While the list price is high, the combination of biosimilar competition, manufacturer savings programs, and patient assistance means most patients can find a way to afford their treatment. The key is knowing your options and asking for help.
Start by talking to your doctor about lower-cost biosimilar options. Then explore copay cards and patient assistance programs. And use Medfinder to find the best price at pharmacies near you.
For more information:
You focus on staying healthy. We'll handle the rest.
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