

A practical guide for healthcare providers on helping patients find Vyvanse (lisdexamfetamine) in stock—actionable steps, alternative options, and workflow tips.
Your patients are frustrated. They've called five pharmacies, been told "we don't have it," and now they're calling your office. If you prescribe Vyvanse (lisdexamfetamine dimesylate) for ADHD or binge eating disorder, this guide gives you actionable steps to help your patients find their medication—and streamline the process for your practice.
Here's the quick snapshot: Brand Vyvanse (Takeda) is not in shortage and is generally available at most pharmacies, though at a higher cost ($400–$558/month without insurance). Generic lisdexamfetamine remains in shortage from some suppliers, despite 11 FDA-approved generic manufacturers and a 24% DEA production quota increase approved in late 2024.
Supply is improving, but the gap between "technically available" and "my patient can fill their prescription today" remains real.
Several factors contribute to ongoing availability challenges:
Here are five actionable steps you and your team can take:
The Medfinder provider portal lets you search for pharmacies with Vyvanse or generic lisdexamfetamine in stock on behalf of your patients. Medfinder's dedicated support team contacts pharmacies directly to verify real-time availability—saving your staff from making dozens of calls.
Encourage patients to contact their pharmacy at least one week before their refill is due. This gives the pharmacy time to order stock or for your patient to locate an alternative pharmacy. For a Schedule II controlled substance like Vyvanse, prescriptions cannot be transferred between pharmacies in most states, so planning ahead is especially important.
Independent pharmacies often use different wholesalers than chain pharmacies and may have more flexibility in ordering controlled substances. They may also carry less common dosage strengths. Encourage your patients to expand their search beyond CVS, Walgreens, and Walmart.
When clinically appropriate, discuss dosage flexibility with your patients. If their usual 50mg dose is unavailable, adjacent strengths (40mg or 60mg) may be in stock. Only make this adjustment when medically sound—but knowing that dose-specific shortages exist can inform your prescribing decisions.
Cost barriers compound availability issues. Make sure your patients know about:
If a patient truly cannot access Vyvanse or generic lisdexamfetamine, consider these alternatives based on their clinical profile:
For a comprehensive list of alternatives, see our alternatives to Vyvanse guide.
Medication access issues consume staff time. Here are ways to make the process more efficient:
You're not just a prescriber—you're a patient advocate. In a landscape where medication access is unpredictable, proactive steps from your practice can make the difference between a patient who stays on therapy and one who gives up.
The Medfinder provider portal is designed to help providers like you cut through the noise and find pharmacies with Vyvanse in stock—without the phone tag.
For more on the Vyvanse shortage, see our provider shortage briefing. To help patients manage cost, check out our provider's guide to Vyvanse savings programs.
You focus on staying healthy. We'll handle the rest.
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