Is Ethosuximide Still Hard to Find in 2026?

If you've had trouble picking up your Ethosuximide prescription lately, you're probably wondering: is there an official shortage? The short answer is that Ethosuximide is not currently listed on the FDA or ASHP drug shortage databases as of early 2026. But that doesn't mean it's easy to find.

Ethosuximide (brand name: Zarontin) is a niche anticonvulsant used primarily for absence seizures. Because it serves a relatively small patient population and only a few companies manufacture it, availability can be inconsistent—even without a formal shortage declaration. Many patients report difficulty finding it at their local pharmacies.

Why Is Ethosuximide Hard to Find Right Now?

Even without an official shortage, several factors can make Ethosuximide difficult to locate:

Low Pharmacy Stocking Rates

Most retail pharmacies stock medications based on how frequently they're dispensed. Ethosuximide is prescribed far less often than common medications like blood pressure pills or diabetes drugs. As a result, many pharmacies—especially large chains—simply don't keep it on their shelves.

Limited Manufacturers

Only a small number of pharmaceutical companies produce generic Ethosuximide. Pfizer manufactures the brand-name Zarontin oral solution. With so few producers, any disruption in manufacturing can create ripple effects across the supply chain.

Wholesaler Allocation

When supply is limited, wholesalers may allocate stock to their highest-volume pharmacy customers first. This can leave smaller or independent pharmacies—which may actually be more willing to order Ethosuximide—waiting for their shipments.

Intermittent Regional Shortages

Even if Ethosuximide is technically available nationally, it may be out of stock in your specific region. Supply chain logistics mean that some areas experience temporary gaps more than others.

How Much Does Ethosuximide Cost in 2026?

Cost is another challenge for Ethosuximide patients. Here's what you can expect:

• Cash price (no insurance): $200 to $580 for a 30-day supply, depending on the formulation and pharmacy
• With a discount card: Generic Ethosuximide can cost as low as $32 with GoodRx or $36 with SingleCare
• Brand-name Zarontin: Significantly more expensive, often $500+ without insurance
• With insurance: Most plans cover generic Ethosuximide with a typical copay of $10 to $50

For a complete guide to saving money, read our post on how to save money on Ethosuximide in 2026.

Are There New Options for Absence Seizure Patients?

While no new medications have been specifically approved for absence seizures in recent years, the existing treatment options remain effective:

• Ethosuximide remains the first-line therapy for absence seizures
• Valproic Acid (Depakote) is equally effective and more widely available
• Lamotrigine (Lamictal) is less effective but better tolerated and preferred for women of childbearing age

If you're considering a switch, our post on alternatives to Ethosuximide covers the pros and cons of each option in detail.

How to Find Ethosuximide in Stock

Here are your best strategies for locating Ethosuximide right now:

1. Use Medfinder

Medfinder helps you search for pharmacies that have Ethosuximide in stock near your location. It's the fastest way to check availability without making dozens of phone calls.

2. Try Independent Pharmacies

Independent pharmacies are often more willing to special-order niche medications. They may also have access to different wholesalers than chain pharmacies.

3. Consider Mail-Order

Mail-order pharmacies operate from large central warehouses and may have better access to less common medications. Check with your insurance plan's mail-order option.

4. Ask About Both Formulations

Ethosuximide is available as 250 mg capsules and a 250 mg/5 mL oral solution. If one form is out of stock, the other may be available. Talk to your prescriber about switching formulations if needed.

5. Plan Ahead

Request refills 1 to 2 weeks early so your pharmacy has time to order Ethosuximide if they don't have it in stock.

For more detailed tips, see our guide on how to find Ethosuximide in stock near you.

Final Thoughts

While there is no official Ethosuximide shortage in 2026, the reality on the ground is that many patients struggle to find it. The combination of low demand, limited manufacturers, and inconsistent pharmacy stocking creates a situation where this important seizure medication can feel scarce.

The best thing you can do is plan ahead, use tools like Medfinder, and keep your neurologist informed. If you're having ongoing difficulty, ask about alternatives or reach out to Pfizer's patient assistance program (Pfizer RxPathways: 1-844-989-4366) for additional support.

Stay informed about your medication. For a complete overview, read What is Ethosuximide?