# Medfinder — Complete Knowledge Base > Medfinder is the #1 Rated Medication Locating Service, having helped 45,454 patients locate their medications at in stock pharmacies near them. We use voice AI to call pharmacies on patients' behalf, eliminating the burden of calling around during drug shortages. 99% success rate across 60,000+ pharmacies nationwide. Generated: 2026-10-20 | Source: https://medfinder.com --- ## Trust & Accreditations - Medfinder is a BBB Accredited Business (A+ rating, accredited 2026-08-25): https://www.bbb.org/us/ma/boston/profile/mental-health-services/medfinder-0021-574920 - Medfinder is LegitScript Certified: https://www.legitscript.com/websites/?checker_keywords=medfinder.com - NPI 1114858347 (NPPES): https://npiregistry.cms.hhs.gov/provider-view/1114858347 --- ## Core Pages # About Medfinder Medfinder helps patients find pharmacies with their medications in stock. We use voice AI to call pharmacies on patients' behalf, eliminating the burden of calling around during drug shortages. Founded to solve the medication access crisis in America, Medfinder has helped thousands of patients find their prescriptions when pharmacies say "we don't have it." Our voice AI technology calls pharmacies in your area, checks real-time stock, and tells you exactly where to go — so you never have to make another phone call. - 99% success rate finding medications - 60,000+ pharmacies nationwide - Results in minutes, not hours # How Medfinder Works 1. **Tell us your medication** — Enter the medication you need and your location. 2. **We search for you** — Our voice AI calls pharmacies in your area to check real-time stock availability. 3. **Pick up your prescription** — We send you a list of pharmacies that have your medication in stock. Take it to your pharmacy of choice. Subscribe to get the best prices on searches. $210 annually for 12 searches. $35/mo for 1 search each month. One-time 1/3/6-search packages are also available. No hidden fees; searches never expire. # Medfinder Pricing Medfinder offers subscription plans plus one-time packages: **Subscriptions (best value):** - **Annual** — $210/year, 12 searches upfront ($17.50/search, save 50%) - **Monthly** — $35/month, 1 search per month **One-time packages (also available):** - **Single Search** — $50 (1 search) - **3-Pack** — $120 (3 searches, $40 each, save 20%) - **6-Pack** — $180 (6 searches, $30 each, save 40%) All plans include full pharmacy availability results, real-time stock verification, and support. Searches never expire; money-back guarantee; cancel anytime. # Medfinder for Healthcare Providers Medfinder assists healthcare providers in locating in-stock medications for patients, reducing delays and improving care continuity. When you prescribe a medication and your patient can't find it, Medfinder's voice AI does the pharmacy calling for them. Providers can purchase search packs for their patients or direct patients to medfinder.com. # Medfinder Data Verification Methodology Medfinder public shortage tracker pages summarize availability signals from Medfinder pharmacy checks, patient search activity, and official public sources such as the FDA Drug Shortages database. Metrics include total pharmacy checks, in-stock rate, availability score, patient shortage reports, last verified date, and last in-stock report date. Public tracker data is directional and does not guarantee that a pharmacy can fill a prescription. Public shortage tracker pages are recomputed every 6 hours. FDA shortage records are ingested daily before the morning shortage tracker refresh, and medication name normalization is refreshed daily. Public pharmacy check metrics use a last 30 days reporting window. Use of Medfinder public shortage tracker data, availability metrics, regional snapshots, and public JSON feeds is subject to the Medfinder Terms of Service at https://www.medfinder.com/terms-of-service. --- ## Medications Directory (913 medications) ### Abilify **Generic:** Abilify Findability: 65/100 | Shortage: monitoring | Insurance: $10–$30/mo (generic w/ insurance) | Cash: $10–$50/mo (generic), $800–$1,200/mo (brand) Abilify (Aripiprazole) is an atypical antipsychotic medication manufactured by Otsuka Pharmaceutical and Bristol-Myers Squibb. It is FDA-approved to treat a range of mental health conditions, including: Schizophrenia in adults and adolescents (ages 13–17) Manic or mixed episodes associated with Bipolar I Disorder in adults and pediatric patients (ages 10–17) Adjunctive treatment for Major Depressive Disorder (MDD) in adults Irritability associated with Autistic Disorder in pediatric... ### Absorica **Generic:** Absorica Findability: 58/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $58–$1,600 What Is Absorica? Absorica is a brand-name prescription medication containing Isotretinoin, a powerful retinoid (vitamin A derivative) used to treat severe recalcitrant nodular acne that has not responded to other treatments, including antibiotics. It is manufactured by Sun Pharma and was approved by the FDA as a formulation that can be taken with or without food — unlike older isotretinoin formulations that required a high-fat meal for proper absorption. Absorica is typically prescribed as a... ### Acamprosate **Generic:** Acamprosate Findability: 35/100 | Shortage: active | Insurance: $10–$50 | Cash: $68–$340 What Is Acamprosate? Acamprosate (Acamprosate Calcium) is an FDA-approved medication used to help maintain abstinence from alcohol in adults who have alcohol dependence and are already abstinent when starting treatment. It was originally marketed under the brand name Campral, which has since been discontinued — only generic versions are currently available. Acamprosate is classified as a GABA analogue and works by restoring the chemical balance in the brain that is disrupted by chronic... ### Acarbose **Generic:** acarbose Findability: 82/100 | Insurance: $5–$15 | Cash: $19–$90 What Is Acarbose? Acarbose is an oral prescription medication in the drug class known as alpha-glucosidase inhibitors, used as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. The brand-name version, Precose (manufactured by Bayer), has been discontinued; only generic acarbose is available as of 2026. Unlike many diabetes medications that work systemically, acarbose acts locally in the gut. It inhibits enzymes that break down complex... ### Accutane **Generic:** Accutane Findability: 60/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $40–$500 What Is Accutane? Accutane is the original brand name for Isotretinoin, a powerful oral retinoid (vitamin A derivative) used to treat severe recalcitrant nodular acne that has not responded to other treatments, including oral antibiotics. While the Accutane brand was discontinued by Roche in 2009, several generic versions remain widely available, including Amnesteem, Claravis, Myorisan, Zenatane, and the micronized formulation Absorica. Isotretinoin is one of the most effective acne treatments... ### Acetaminophen/Caffeine **Generic:** acetaminophen/caffeine Findability: 92/100 | Insurance: $0–$10 | Cash: $5–$20 What Is Acetaminophen/Caffeine? Acetaminophen/caffeine is an over-the-counter combination pain reliever that pairs acetaminophen — the active ingredient in Tylenol — with caffeine, which acts as an analgesic adjuvant to boost and prolong pain relief. It is sold under brand names including Excedrin Tension Headache, Excedrin Mild Headache, Excedrin Quick Tab, and Valorin Extra. Unlike Excedrin Extra Strength or Excedrin Migraine, this formulation does NOT contain aspirin. It is used for the... ### Acetic Acid **Generic:** acetic acid Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $15–$40 What Is Acetic Acid Otic? Acetic acid otic solution (2%) is a prescription antiseptic ear drop used to treat otitis externa — the outer ear infection commonly known as swimmer's ear. It is also available in a combination product with hydrocortisone (Acetasol HC, Vosol HC) for cases requiring both antimicrobial and anti-inflammatory treatment. The original brand name was VoSol, which was discontinued in the U.S. market. The FDA confirmed in May 2025 that VoSol's withdrawal was not for safety... ### Acetylcysteine **Generic:** Acetylcysteine Findability: 82/100 | Insurance: $0–$30 | Cash: $10–$206 What Is Acetylcysteine? Acetylcysteine — also known as N-Acetylcysteine (NAC) — is a versatile medication used primarily as a life-saving antidote for acetaminophen (Tylenol) overdose and as a mucolytic agent to break up thick mucus in respiratory conditions. It belongs to two drug classes: antidotes and mucolytics. For acetaminophen poisoning, Acetylcysteine is considered the standard of care and can prevent severe liver damage when administered within 8–10 hours of ingestion. As a... ### Actemra **Generic:** tocilizumab Findability: 65/100 | Shortage: resolved | Insurance: $0–$150 | Cash: $2,308–$4,956 What Is Actemra? Actemra is the brand name for tocilizumab, a biologic medication manufactured by Genentech (a member of the Roche Group). It belongs to a class of drugs called interleukin-6 (IL-6) receptor antagonists — humanized monoclonal antibodies that target a specific protein in the immune system responsible for driving chronic inflammation. Actemra has seven FDA-approved indications: moderate-to-severe rheumatoid arthritis (RA) in adults, giant cell arteritis (GCA) in adults, systemic... ### Actonel 35 12-Week **Generic:** Risedronate Sodium Findability: 45/100 | Shortage: active | Insurance: $0–$15 | Cash: $22–$50 What Is Actonel 35 12-Week? Actonel 35 12-Week is a brand-name prescription medication containing Risedronate Sodium 35 mg, taken as one tablet per week. It is dispensed as a 12-tablet blister pack — a convenient 3-month (12-week) supply. Risedronate belongs to a class of drugs called bisphosphonates, the most commonly prescribed medications for osteoporosis. Actonel is manufactured by Allergan (now part of AbbVie). Generic Risedronate Sodium 35 mg is widely available and therapeutically... ### Adalimumab **Generic:** Adalimumab Findability: 60/100 | Shortage: monitoring | Insurance: $5–$150 | Cash: $1,300–$11,000 What Is adalimumab? Adalimumab is a biologic medication classified as a TNF (tumor necrosis factor) inhibitor. Originally marketed as Humira by AbbVie, it is now available as multiple biosimilar products including Amjevita, Cyltezo, Hadlima, Hyrimoz, Hulio, Yusimry, Yuflyma, and others. Adalimumab is FDA-approved to treat a wide range of autoimmune and inflammatory conditions, including: Rheumatoid arthritis (RA) Psoriatic arthritis (PsA) Ankylosing spondylitis (AS) Crohn's disease... ### Adderall **Generic:** amphetamine mixed salts Findability: 35/100 | Shortage: active | Insurance: $0–$60 | Cash: $15–$350 What Is Adderall? Adderall is the brand name for a combination of four amphetamine salts: dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfate. It is classified as a central nervous system (CNS) stimulant and is one of the most widely prescribed medications in the United States, with over 32 million prescriptions filled in 2023 alone. Adderall is FDA-approved to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in adults and... ### Adderall IR **Generic:** Adderall IR Findability: 35/100 | Shortage: active | Insurance: $0–$30 | Cash: $15–$80 What Is Adderall IR? Adderall IR (Immediate-Release) is a prescription CNS stimulant containing a mixture of Amphetamine and Dextroamphetamine salts (75% Dextroamphetamine and 25% Levoamphetamine). It is FDA-approved to treat Attention Deficit Hyperactivity Disorder (ADHD) and Narcolepsy. The immediate-release formulation typically lasts 4–6 hours per dose, making it suitable for patients who need flexible dosing throughout the day. It is one of the most widely prescribed stimulant... ### Adderall XR **Generic:** Adderall Findability: 35/100 | Shortage: active | Insurance: $15–$30 | Cash: $20–$50 What Is Adderall XR? Adderall XR (amphetamine/dextroamphetamine mixed salts extended-release) is a prescription stimulant medication used primarily to treat Attention Deficit Hyperactivity Disorder (ADHD) in children (ages 6+) and adults. It is one of the most widely prescribed ADHD medications in the United States, with over 26 million prescriptions written annually. The "XR" stands for extended-release. Unlike immediate-release Adderall (Adderall IR), which needs to be taken 2–3 times per... ### Addyi **Generic:** Addyi Findability: 55/100 | Shortage: monitoring | Insurance: $20–$50 | Cash: $149–$1,173 What Is Addyi? Addyi (Flibanserin) is an FDA-approved prescription medication used to treat hypoactive sexual desire disorder (HSDD) in both premenopausal and postmenopausal women under 65 years of age. HSDD is characterized by a persistent lack of sexual desire that causes personal distress and is not explained by other medical conditions, relationship issues, or medication side effects. In a landmark decision in December 2025, the FDA expanded Addyi's approval to include postmenopausal women... ### Adefovir **Generic:** adefovir dipivoxil Findability: 72/100 | Insurance: $10–$75 | Cash: $520–$1,260 What Is Adefovir? Adefovir dipivoxil — sold under the brand name Hepsera — is an antiviral medication approved by the FDA for the treatment of chronic hepatitis B virus (HBV) infection. It is indicated for adults and adolescents aged 12 and older with evidence of active viral replication and persistent liver inflammation or damage. Adefovir belongs to the class of nucleotide analog reverse transcriptase inhibitors (NtRTIs). Originally developed by Gilead Sciences and approved in 2002 as... ### Adempas **Generic:** Adempas Findability: 35/100 | Shortage: active | Insurance: $0–$100/mo | Cash: $14,000–$15,000/mo Adempas (riociguat) is a prescription medication manufactured by Bayer used to treat two forms of pulmonary hypertension: Chronic thromboembolic pulmonary hypertension (CTEPH) — Adempas is the only FDA-approved medication for adults with inoperable or persistent/recurrent CTEPH after surgery, to improve exercise capacity and WHO functional class. Pulmonary arterial hypertension (PAH) — Adempas is approved to improve exercise capacity, improve WHO functional class, and delay clinical worsening... ### Adenocard **Generic:** adenosine Findability: 72/100 | Insurance: $0–$50 copay | Cash: $58–$200+ What Is Adenocard? Adenocard is the brand name for adenosine injection, a sterile intravenous (IV) solution containing 3 mg of adenosine per milliliter. Adenosine is a naturally occurring nucleoside found in every cell of the human body, where it plays critical roles in energy metabolism and cellular signaling. As a medication, it is classified as a Group V antiarrhythmic and cardiac stressing agent. Adenocard is approved by the FDA for conversion of paroxysmal supraventricular tachycardia... ### Adenovirus Type 4 And Type 7 Vaccine, Live, Oral **Generic:** adenovirus type 4 and type 7 vaccine, live, oral Findability: 20/100 | Insurance: N/A (not covered by civilian insurance) | Cash: N/A (DoD-funded) What Is the Adenovirus Type 4 and Type 7 Vaccine? The Adenovirus Type 4 and Type 7 Vaccine, Live, Oral is an FDA-licensed live oral vaccine indicated for active immunization for the prevention of febrile acute respiratory disease (ARD) caused by adenovirus types 4 and 7. It was first approved by the FDA on March 16, 2011 (FDA license BL 125296), and is manufactured by Barr Labs, Inc. (now Teva Women's Health, Inc.). This vaccine is approved exclusively for U.S. military populations aged 17... ### Adipex-P **Generic:** Adipex-P Findability: 70/100 | Shortage: monitoring | Insurance: $5–$25 | Cash: $4–$115 What Is Adipex-P? Adipex-P is the brand name for Phentermine Hydrochloride, a prescription weight-loss medication approved by the FDA for short-term use (a few weeks) in adults with obesity. It is indicated for patients with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition such as hypertension, diabetes, or high cholesterol. Adipex-P is meant to be used alongside a reduced-calorie diet and exercise program. It belongs to the sympathomimetic amine class... ### Adlyxin Starter Kit **Generic:** lixisenatide Findability: 5/100 | Shortage: active | Insurance: N/A (Discontinued) | Cash: N/A (Discontinued) What Is the Adlyxin Starter Kit? The Adlyxin Starter Kit was a two-pen initiation package for adults beginning lixisenatide therapy for type 2 diabetes mellitus. It contained one green prefilled pen (50 mcg/mL; 14 doses of 10 mcg for the first 14 days) and one burgundy prefilled pen (100 mcg/mL; 14 doses of 20 mcg for days 15–28), together providing a full 28-day supply. Manufactured by Sanofi, Adlyxin (lixisenatide) was FDA-approved in July 2016 as an adjunct to diet and exercise to improve... ### Adthyza **Generic:** Adthyza Findability: 2/100 | Shortage: active | Insurance: $20–$50 | Cash: $29–$38 What Is Adthyza? Adthyza was a natural desiccated thyroid (NDT) medication manufactured by Azurity Pharmaceuticals (formerly Silvergate Pharmaceuticals). It contained both levothyroxine (T4) and liothyronine (T3) derived from porcine (pig) thyroid glands. Adthyza was prescribed for the treatment of hypothyroidism — a condition where the thyroid gland doesn't produce enough thyroid hormones. Adthyza was also used for pituitary TSH suppression in patients with thyroid nodules or multinodular... ### Advair **Generic:** Advair Findability: 82/100 | Insurance: $10–$50 | Cash: $50–$500 What Is Advair? Advair is a combination inhaler containing two medications: fluticasone propionate (an inhaled corticosteroid) and salmeterol (a long-acting beta-2 agonist, or LABA). It is manufactured by GlaxoSmithKline (GSK). Advair is FDA-approved for: Asthma maintenance treatment — twice-daily use in patients aged 4+ (Diskus) or 12+ (HFA) COPD maintenance treatment — for airflow obstruction in chronic bronchitis and/or emphysema (Advair Diskus 250/50 only) Reducing COPD exacerbations —... ### Adzenys **Generic:** Adzenys Findability: 35/100 | Shortage: active | Insurance: $50–$100+ | Cash: $113–$655 What Is Adzenys? Adzenys XR-ODT is a prescription stimulant medication used to treat ADHD in children (ages 6+) and adults. It contains amphetamine (the same class of active ingredient as Adderall) in a unique orally disintegrating tablet (ODT) format that dissolves on the tongue without water. Manufactured by Neos Therapeutics (now Ayala Pharmaceuticals), Adzenys was FDA-approved in 2016. It uses XR-ODT technology to deliver extended-release amphetamine in a convenient dissolvable format —... ### Afinitor **Generic:** Afinitor Findability: 62/100 | Shortage: monitoring | Insurance: $0–$4,800 | Cash: $90–$19,300 What Is Afinitor? Afinitor is the brand name for Everolimus, a targeted cancer therapy classified as an mTOR (mammalian target of rapamycin) kinase inhibitor. It is manufactured by Novartis Pharmaceuticals. Afinitor is FDA-approved for several conditions: Advanced HR+/HER2- breast cancer in combination with Exemestane, after failure of Letrozole or Anastrozole Progressive neuroendocrine tumors (NET) of the GI tract, lung, or pancreas that are unresectable or metastatic Advanced renal cell... ### Afirmelle 28 Day **Generic:** Afirmelle 28 Day Findability: 82/100 | Insurance: $0–$25 | Cash: $9–$50 What Is Afirmelle 28 Day? Afirmelle 28 Day is a monophasic combination oral contraceptive pill used to prevent pregnancy. Each active tablet contains Levonorgestrel 0.1 mg (a progestin) and Ethinyl Estradiol 0.02 mg (an estrogen). It is the generic equivalent of Alesse, which has been discontinued in the United States. Afirmelle comes in a 28-day pack with 21 active hormone tablets and 7 inert reminder tablets to help maintain a daily pill-taking routine. Afirmelle 28 Day is manufactured by... ### Afrezza **Generic:** Afrezza Findability: 55/100 | Shortage: monitoring | Insurance: $35–$75 | Cash: $99–$2,320 What Is Afrezza? Afrezza (insulin human) Inhalation Powder is the only FDA-approved ultra rapid-acting inhaled insulin for adults with Type 1 or Type 2 diabetes. Unlike traditional injectable insulins, Afrezza is breathed in through the mouth using a small, whistle-sized inhaler at the beginning of a meal. It uses MannKind's proprietary Technosphere technology to deliver insulin directly to the lungs, where it is rapidly absorbed into the bloodstream. Afrezza was FDA-approved in 2014 and is... ### AirDuo RespiClick **Generic:** fluticasone propionate / salmeterol Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $55–$165 What Is AirDuo RespiClick? AirDuo RespiClick was a brand-name combination asthma maintenance inhaler manufactured by Teva Respiratory. It contained two active ingredients: fluticasone propionate (an inhaled corticosteroid) and salmeterol (a long-acting beta-2 agonist). It was delivered via the RespiClick breath-activated multidose dry powder inhaler (MDPI) and was FDA-approved for maintenance treatment of asthma in patients 12 years and older. Teva discontinued the AirDuo RespiClick brand on... ### Airsupra **Generic:** Airsupra Findability: 55/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $249–$737 What Is Airsupra? Airsupra is a prescription metered-dose inhaler that combines two active ingredients — albuterol sulfate (a short-acting beta2-agonist, or SABA) and budesonide (an inhaled corticosteroid, or ICS) — in a single rescue inhaler. It is approved for adults 18 and older for as-needed treatment or prevention of bronchoconstriction in asthma and to reduce the risk of asthma exacerbations. Airsupra is the first FDA-approved rescue inhaler to include an anti-inflammatory... ### Ajovy **Generic:** Ajovy Findability: 68/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $690–$1,019 What Is Ajovy? Ajovy (Fremanezumab-Vfrm) is a prescription injectable medication used for the preventive treatment of migraine in adults and pediatric patients aged 12 years and older (weighing at least 45 kg). It belongs to a class of drugs called CGRP inhibitors (calcitonin gene-related peptide inhibitors). Ajovy is manufactured by Teva Pharmaceuticals and was designed specifically to reduce the number of migraine days per month — it is not used to treat a migraine attack that has already... ### Aklief **Generic:** Aklief Findability: 58/100 | Shortage: monitoring | Insurance: $20–$75 | Cash: $90–$1,080 What Is Aklief? Aklief (Trifarotene) is a prescription topical retinoid cream used to treat acne vulgaris in patients 9 years of age and older. It is the first new retinoid molecule approved for acne treatment in over 20 years and is manufactured by Galderma Laboratories. Unlike older retinoids that are typically limited to facial acne, Aklief was specifically studied for use on the face, chest, shoulders, and back — making it a unique option for patients dealing with truncal (body) acne. It... ### Alfuzosin XR **Generic:** alfuzosin hydrochloride Findability: 72/100 | Insurance: $0–$30 | Cash: $8–$115 What Is Alfuzosin XR? Alfuzosin XR (alfuzosin hydrochloride extended-release) is a prescription alpha-1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH) — an enlarged prostate — in adult men. It is the generic equivalent of the brand-name drug Uroxatral, which was first approved by the FDA in 2003. Alfuzosin XR is available as a 10 mg extended-release tablet taken once daily with food. It is not approved for women, children, or as a treatment for hypertension.... ### Alinia **Generic:** nitazoxanide Findability: 45/100 | Insurance: $0–$50 | Cash: $223–$1,605 What Is Alinia (Nitazoxanide)? Alinia is the brand name for nitazoxanide, a prescription antiprotozoal medication FDA-approved in 2004. It is manufactured by Romark Laboratories and is available in two forms: 500 mg film-coated tablets (for patients 12 years and older) and a 100 mg/5 mL strawberry-flavored oral suspension (for patients 1 year and older). A generic version of nitazoxanide was approved by the FDA in 2020. Alinia is used to treat diarrhea caused by the intestinal parasites... ### Allday 5000 **Generic:** sodium fluoride 1.1% toothpaste Findability: 72/100 | Insurance: $0–$30 | Cash: $15–$45 What Is Allday 5000? Allday 5000 is a prescription-strength fluoride toothpaste manufactured by Elevate Oral Care. Its active ingredient is sodium fluoride 1.1% — equivalent to 5000 ppm (parts per million) fluoride ion — which is five times the concentration found in standard over-the-counter toothpastes (typically 1000–1500 ppm). It is classified as a human prescription drug with NDC 57511-0005. The "5000" in the name refers to this 5000 ppm fluoride concentration. Allday 5000 is available... ### Allopurinol **Generic:** allopurinol Findability: 90/100 | Insurance: $0–$30 | Cash: $8–$90 What Is Allopurinol? Allopurinol is a prescription medication belonging to the xanthine oxidase inhibitor (XOI) drug class. It is primarily used to lower uric acid levels in the blood and urine, making it the cornerstone treatment for chronic gout and hyperuricemia. It has been FDA-approved since 1966 and is sold under the brand names Zyloprim, Lopurin, and Aloprim (IV formulation). Allopurinol is FDA-approved for three indications: preventing gout attacks in patients with chronic gout and... ### Alprazolam **Generic:** Alprazolam Findability: 78/100 | Insurance: $0–$15 | Cash: $10–$335 What Is Alprazolam? Alprazolam is a prescription benzodiazepine medication most commonly known by its brand name Xanax. It is FDA-approved for the treatment of generalized anxiety disorder (GAD) and panic disorder, with or without agoraphobia. It is also sometimes prescribed off-label for anxiety associated with depression. Alprazolam is classified as a short-acting benzodiazepine, meaning it takes effect quickly (usually within 15 to 30 minutes) and its effects wear off relatively fast... ### Altavera 28 Day **Generic:** levonorgestrel and ethinyl estradiol Findability: 80/100 | Insurance: $0–$15 | Cash: $5–$72 What Is Altavera 28 Day? Altavera 28 Day is a combination oral contraceptive (COC) containing two synthetic hormones: levonorgestrel (0.15 mg), a progestin, and ethinyl estradiol (0.03 mg), an estrogen. It is manufactured by Xiromed, LLC (distributed in the U.S.) and produced by Laboratorios Leon Farma S.A. in Spain. Altavera is a generic equivalent of the discontinued brand Nordette and has been FDA-approved for the prevention of pregnancy in females of reproductive potential. Each Altavera... ### Altreno **Generic:** tretinoin Findability: 60/100 | Insurance: $0–$60 | Cash: $126–$400 What Is Altreno? Altreno is a brand-name prescription topical medication manufactured by Ortho Dermatologics (Bausch Health Companies). It contains 0.05% tretinoin — the biologically active acid form of vitamin A (all-trans retinoic acid) — formulated in a lotion base. FDA-approved in August 2018, Altreno is the first and only tretinoin 0.05% product available in a lotion formulation. Altreno is FDA-approved for the topical treatment of acne vulgaris in patients 9 years of age and older. It... ### Aluminum Hydroxide/Magnesium Hydroxide **Generic:** aluminum hydroxide/magnesium hydroxide Findability: 92/100 | Insurance: $0 | Cash: $6–$15 What Is Aluminum Hydroxide/Magnesium Hydroxide? Aluminum hydroxide and magnesium hydroxide are two antacid compounds combined in a single OTC product. Together, they neutralize stomach acid to relieve heartburn, acid indigestion, sour stomach, and upset stomach. This combination antacid is available under brand names including Mylanta and as store-brand generics at virtually every major pharmacy chain in the United States. The brand-name Maalox has been discontinued in the U.S. market, but... ### Alvesco **Generic:** Alvesco Findability: 60/100 | Shortage: monitoring | Insurance: $15–$75 | Cash: $275–$411 What Is Alvesco? Alvesco (Ciclesonide) is an inhaled corticosteroid (ICS) used for the maintenance treatment of asthma in adults and children aged 12 and older. It is a preventive medication — meaning it is taken daily to control and prevent asthma symptoms, not as a rescue inhaler for sudden breathing difficulties. Alvesco is manufactured by Covis Pharma, which acquired the drug from AstraZeneca in 2018. Ciclesonide is unique among inhaled corticosteroids because it is a prodrug — it only... ### Alyacen 1/35 **Generic:** norethindrone and ethinyl estradiol Findability: 62/100 | Insurance: $0–$20 | Cash: $25–$77 What Is Alyacen 1/35? Alyacen 1/35 is a combination oral contraceptive pill (OCP) manufactured by Glenmark Pharmaceuticals. It is a branded generic equivalent of Ortho-Novum 1/35 and contains two active synthetic hormones: norethindrone 1 mg (a progestin) and ethinyl estradiol 0.035 mg (a synthetic estrogen). It is available in a 28-day blister pack containing 21 active peach tablets and 7 inert light-green reminder tablets. Alyacen 1/35 is FDA-approved for the prevention of pregnancy and is... ### Ambrisentan **Generic:** ambrisentan Findability: 72/100 | Shortage: resolved | Insurance: $0–$200 | Cash: $2,000–$14,200 What Is Ambrisentan? Ambrisentan, sold under the brand name Letairis by Gilead Sciences, is an FDA-approved medication for adults with pulmonary arterial hypertension (PAH, WHO Group 1). It belongs to a class of drugs called endothelin receptor antagonists (ERAs) and was first approved by the FDA in June 2007. Generic ambrisentan became available beginning in 2019 from multiple manufacturers including Apotex, Cipla USA, Mylan, Sun Pharma, Teva, and Zydus. Ambrisentan is indicated to improve... ### Amcinonide **Generic:** Amcinonide Findability: 5/100 | Shortage: active | Insurance: $10–$50 | Cash: $109–$2,400 What Is Amcinonide? Amcinonide is a high-potency synthetic topical corticosteroid used to treat inflammatory skin conditions. It is classified as a Class II (ointment) to Class III (cream) corticosteroid on the potency scale, making it one of the stronger options for treating stubborn skin inflammation. Amcinonide is FDA-approved to treat atopic dermatitis, allergic contact dermatitis, eczema, plaque-type psoriasis, and other corticosteroid-responsive dermatoses. It was originally marketed... ### Amethyst 28 Day **Generic:** levonorgestrel and ethinyl estradiol Findability: 78/100 | Insurance: $0–$30 | Cash: $58–$68 What Is Amethyst 28 Day? Amethyst 28 Day is a combination oral contraceptive containing levonorgestrel 90 mcg and ethinyl estradiol 20 mcg. Manufactured by Teva Pharmaceuticals, it is the generic equivalent of Lybrel — the first FDA-approved continuous-cycle oral contraceptive, which has since been discontinued as a brand. What makes Amethyst 28 Day unique is that all 28 tablets are active hormone tablets — there are no placebo pills. Unlike standard 28-day packs that include 7 placebo pills... ### Amifampridine **Generic:** amifampridine Findability: 45/100 | Insurance: $0–$2,000 | Cash: $31,000–$34,000 What Is Amifampridine? Amifampridine (brand name Firdapse) is a prescription oral medication and the only FDA-approved treatment for Lambert-Eaton Myasthenic Syndrome (LEMS), a rare autoimmune disorder affecting the neuromuscular junction. Also known as 3,4-diaminopyridine (3,4-DAP), it has been used to treat LEMS since the 1990s — first through compassionate use programs and then through formal FDA approval in November 2018. LEMS affects approximately 1 in 100,000 people in the United States... ### Aminocaproic Acid **Generic:** Aminocaproic Acid Findability: 45/100 | Shortage: active | Insurance: $10–$50 | Cash: $32–$650 What Is Aminocaproic Acid? Aminocaproic Acid (also known by the brand name Amicar) is an antifibrinolytic hemostatic agent used to treat and prevent excessive bleeding caused by hyperfibrinolysis — a condition where the body breaks down blood clots too quickly. It is FDA-approved for acute bleeding syndromes due to elevated fibrinolytic activity, including hemorrhagic complications following cardiac surgery, bleeding associated with hematological disorders, hepatic cirrhosis, and neoplastic... ### Aminophylline **Generic:** Aminophylline Findability: 4/100 | Shortage: active | Insurance: $0–$50 | Cash: $278–$400+ What Is Aminophylline? Aminophylline is a methylxanthine bronchodilator that combines Theophylline with Ethylenediamine to improve its water solubility. It is used as an adjunct treatment for acute asthma exacerbations and reversible airway obstruction associated with chronic lung diseases such as emphysema and COPD. In the body, Aminophylline releases Theophylline — the active compound — which relaxes the smooth muscles in the airways, making it easier to breathe. While Aminophylline was... ### Amlodipine **Generic:** Amlodipine Findability: 92/100 | Insurance: $0–$10 | Cash: $4–$65 What Is Amlodipine? Amlodipine is a calcium channel blocker (dihydropyridine class) used to treat high blood pressure (hypertension), chronic stable angina, and vasospastic (Prinzmetal's) angina. It is also prescribed to reduce the risk of hospitalization for angina and coronary revascularization in patients with coronary artery disease. Originally marketed as Norvasc by Pfizer, Amlodipine has been available as an affordable generic since 2007. It is FDA-approved for adults and children ages... ### Amlodipine/Telmisartan **Generic:** Amlodipine/Telmisartan Findability: 55/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $123–$250 What Is Amlodipine/Telmisartan? Amlodipine/Telmisartan is a combination blood pressure medication that contains two active ingredients in a single tablet. It combines an angiotensin II receptor blocker (ARB) with a calcium channel blocker (CCB) to lower blood pressure more effectively than either drug alone. It is prescribed for hypertension (high blood pressure) — particularly when a single blood pressure medication isn't enough to reach target levels, or as initial combination therapy in... ### Amoxicillin/Clavulanate **Generic:** Amoxicillin/Clavulanate Findability: 75/100 | Insurance: $0–$15 | Cash: $10–$60 What is Amoxicillin/Clavulanate and what does it do? Amoxicillin/Clavulanate (brand name Augmentin) is a combination antibiotic used to treat a wide range of bacterial infections. It combines amoxicillin, a penicillin-type antibiotic, with clavulanate, a beta-lactamase inhibitor that helps amoxicillin work against bacteria that would otherwise resist it. It is FDA-approved for: Lower respiratory tract infections Acute bacterial sinusitis Otitis media (middle ear infections) Skin and skin... ### Amoxicillin/Vonoprazan **Generic:** amoxicillin and vonoprazan Findability: 52/100 | Insurance: $25–$150 | Cash: $835–$1,014 What Is Amoxicillin/Vonoprazan? Amoxicillin/Vonoprazan is a prescription combination medication sold under the brand name Voquezna Dual Pak, manufactured by Phathom Pharmaceuticals. It co-packages two distinct drugs in dosing cards: vonoprazan (a first-in-class potassium-competitive acid blocker, or PCAB) and amoxicillin (a penicillin-class antibiotic). The FDA approved Voquezna Dual Pak on May 3, 2022, for the treatment of Helicobacter pylori (H. pylori) infection in adults. The drug became... ### Amphetamine XR **Generic:** Amphetamine XR Findability: 35/100 | Shortage: active | Insurance: $20–$75 | Cash: $170–$735 What Is Amphetamine XR? Amphetamine XR refers to extended-release formulations of amphetamine used to treat Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. Brand-name products include Dyanavel XR (an extended-release oral suspension), Adzenys XR-ODT (an orally disintegrating tablet), and Adzenys ER (an oral suspension). These medications provide once-daily dosing and are designed to release amphetamine gradually throughout the day, helping improve attention,... ### Amphetamine/Dextroamphetamine **Generic:** Amphetamine/Dextroamphetamine Findability: 35/100 | Shortage: active | Insurance: $0–$30 | Cash: $25–$100 What Is Amphetamine/Dextroamphetamine? Amphetamine/Dextroamphetamine is a central nervous system (CNS) stimulant used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in adults and children aged 3 and older, as well as narcolepsy. It is sold under brand names including Adderall, Adderall XR, and Mydayis. The medication contains a combination of amphetamine salts—75% dextroamphetamine and 25% levoamphetamine—that work together to improve focus, attention, and impulse control. Generic... ### Amphetamine/Dextroamphetamine IR **Generic:** Amphetamine/Dextroamphetamine IR Findability: 35/100 | Shortage: active | Insurance: $0–$30 | Cash: $14–$60 What Is amphetamine/dextroamphetamine ir? Amphetamine/dextroamphetamine IR (commonly known by the brand name Adderall) is a central nervous system (CNS) stimulant composed of mixed amphetamine salts. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults and children aged 3 and older, as well as narcolepsy. The immediate-release (IR) formulation typically lasts 4–6 hours per dose and is usually taken 1–3 times daily. It helps improve focus,... ### Amphetamine/Dextroamphetamine XR **Generic:** Amphetamine/Dextroamphetamine XR Findability: 35/100 | Shortage: active | Insurance: $10–$50 | Cash: $28–$350 What Is Amphetamine/Dextroamphetamine XR? Amphetamine/Dextroamphetamine XR (brand name Adderall XR) is a central nervous system (CNS) stimulant prescribed primarily for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 and older. It contains a combination of four amphetamine salts — dextroamphetamine sulfate, amphetamine sulfate, dextroamphetamine saccharate, and amphetamine aspartate monohydrate — in a 3:1 ratio of dextro- to levo-amphetamine. The... ### Anafranil **Generic:** Anafranil Findability: 55/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $15–$600 What Is Anafranil? Anafranil (Clomipramine Hydrochloride) is a tricyclic antidepressant (TCA) that is FDA-approved for the treatment of Obsessive-Compulsive Disorder (OCD) in patients aged 10 and older. It is widely considered the most effective medication for OCD, particularly when SSRIs have not provided adequate relief. Clomipramine is also used off-label for major depressive disorder, anxiety disorders, panic disorder, chronic pain, and premature ejaculation. ### Analpram HC **Generic:** hydrocortisone/pramoxine Findability: 80/100 | Insurance: $0–$30 | Cash: $40–$390 What Is Analpram HC? Analpram HC is a brand-name prescription topical medication manufactured by Sebela Pharmaceuticals (distributed by Legacy Pharma). It combines two active ingredients: hydrocortisone acetate (a low-potency corticosteroid) and pramoxine hydrochloride (a topical local anesthetic). The most common strength is 2.5%/1% cream, though 1%/1% formulations are also available in cream, lotion, and foam. Analpram HC is primarily used to treat hemorrhoids, anal fissures, anorectal... ### Anastrozole **Generic:** anastrozole Findability: 82/100 | Insurance: $0–$30 | Cash: $9–$258 What Is Anastrozole? Anastrozole is a prescription medication used to treat hormone receptor-positive (HR+) breast cancer in postmenopausal women. It is sold under the brand name Arimidex (made by AstraZeneca), though affordable generic versions are widely available from multiple manufacturers. Anastrozole belongs to a class of drugs called aromatase inhibitors. The drug is FDA-approved for three indications: adjuvant treatment of early HR-positive breast cancer in postmenopausal women... ### Anbesol Cold Sore Therapy **Generic:** allantoin/benzocaine/camphor/petrolatum Findability: 78/100 | Insurance: $0 | Cash: $8–$12 What Is Anbesol Cold Sore Therapy? Anbesol Cold Sore Therapy is a maximum-strength over-the-counter topical ointment manufactured by Haleon US Services (formerly GlaxoSmithKline Consumer Healthcare). It has been marketed since 2006 and is specifically formulated to treat the pain, dryness, and discomfort of fever blisters and cold sores caused by the herpes simplex virus (HSV-1). The product contains four active ingredients: benzocaine 20% (local anesthetic for fast pain numbing), camphor 3%... ### Androgel **Generic:** Androgel Findability: 60/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $85–$1,100 What Is Androgel? Androgel is a prescription testosterone gel used for testosterone replacement therapy (TRT) in adult men diagnosed with hypogonadism — a condition where the body does not produce enough testosterone on its own. It is manufactured by AbbVie Inc. and is available in both brand-name and generic formulations. Androgel is FDA-approved to treat primary hypogonadism (caused by problems with the testes) and hypogonadotropic hypogonadism (caused by problems with the pituitary gland... ### Anucort-HC **Generic:** hydrocortisone acetate Findability: 68/100 | Insurance: $0–$30 | Cash: $32–$264 What Is Anucort-HC? Anucort-HC is the brand name for hydrocortisone acetate 25 mg rectal suppositories, manufactured and distributed by Cosette Pharmaceuticals, Inc. It is a prescription-only topical corticosteroid delivered directly to the rectum via a suppository that melts at body temperature. Anucort-HC is prescribed for inflamed internal hemorrhoids, proctitis (including post-irradiation proctitis), as an adjunct treatment for chronic ulcerative colitis of the rectum, cryptitis, and... ### Anusol HC **Generic:** hydrocortisone acetate rectal Findability: 80/100 | Insurance: $0–$30 | Cash: $15–$80 What Is Anusol HC? Anusol HC is the brand name for hydrocortisone acetate rectal, a prescription topical corticosteroid distributed by Salix Pharmaceuticals, a division of Bausch Health US, LLC. It is used to reduce inflammation in and around the rectum and anus. Anusol HC is available as a 25 mg rectal suppository (prescription only), a 2.5% rectal cream (prescription only), and a 1% cream available over the counter. It is NOT a controlled substance, meaning no DEA scheduling restrictions... ### Apidra **Generic:** insulin glulisine Findability: 60/100 | Insurance: $35–$75 | Cash: $85–$321 What Is Apidra? Apidra is the brand name for insulin glulisine, a rapid-acting recombinant human insulin analog manufactured by Sanofi. It was first approved by the FDA on April 16, 2004, and is indicated to improve glycemic control in adults and children aged 4 years and older with type 1 or type 2 diabetes mellitus. Apidra is a mealtime (prandial) insulin taken before or shortly after meals to prevent blood sugar from rising too high. It is available as a 10 mL vial (100 units/mL) and the... ### Apixaban **Generic:** Apixaban Findability: 60/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $30–$600 What Is Apixaban? Apixaban (brand name Eliquis) is a prescription blood thinner in the class of Direct Oral Anticoagulants (DOACs). It's used to prevent stroke and blood clots in patients with atrial fibrillation, treat deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevent blood clots after hip or knee replacement surgery. Unlike older blood thinners like Warfarin, Apixaban doesn't require regular blood monitoring or strict dietary restrictions. Important 2026 update: Apixaban... ### Apomorphine **Generic:** apomorphine Findability: 42/100 | Insurance: $50–$500 | Cash: $315–$9,500 What Is Apomorphine? Apomorphine is a non-ergoline dopamine agonist used to treat acute "off" episodes in adults with advanced Parkinson's disease. Despite the word "morphine" in its name, it is not an opioid and does not bind to opioid receptors. It was first approved by the FDA in 2004 as Apokyn (subcutaneous injection) and received a second approval in February 2025 as Onapgo, the first wearable continuous subcutaneous infusion device for Parkinson's disease in the United States. "Off"... ### Apremilast **Generic:** Apremilast Findability: 60/100 | Shortage: monitoring | Insurance: $0–$150 | Cash: $5,000–$6,800 What Is Apremilast? Apremilast is an oral phosphodiesterase 4 (PDE4) inhibitor sold under the brand name Otezla, manufactured by Amgen Inc. It is FDA-approved to treat plaque psoriasis in adults (and pediatric patients weighing at least 20 kg) who are candidates for phototherapy or systemic therapy, active psoriatic arthritis in adults, and oral ulcers associated with Behçet's disease in adults. Unlike many other psoriasis and psoriatic arthritis treatments that are injectable biologics,... ### Apretude **Generic:** cabotegravir Findability: 55/100 | Insurance: $0 | Cash: $3,700–$22,000/yr What Is Apretude? Apretude (cabotegravir extended-release injectable suspension) is the brand name for the world's first FDA-approved long-acting injectable HIV pre-exposure prophylaxis (PrEP) medication. Manufactured by ViiV Healthcare and approved by the FDA on December 20, 2021, Apretude is administered as a 600 mg intramuscular injection into the gluteal muscle by a healthcare provider — once every two months after two initiation injections one month apart. Apretude is indicated for... ### Apri 28 Day **Generic:** Apri 28 Day Findability: 65/100 | Shortage: monitoring | Insurance: $0–$0 | Cash: $10–$99 What Is Apri 28 Day? Apri 28 Day is a combined oral contraceptive (birth control pill) that contains two synthetic hormones: desogestrel (a progestin) and ethinyl estradiol (an estrogen). It is FDA-approved for the prevention of pregnancy. Apri is also commonly prescribed off-label for managing acne, regulating irregular menstrual cycles, reducing menstrual cramps (dysmenorrhea), and helping with symptoms of endometriosis and polycystic ovary syndrome (PCOS). Each 28-day pack includes 21... ### Aptensio XR **Generic:** Aptensio XR Findability: 55/100 | Shortage: monitoring | Insurance: $15–$150 | Cash: $80–$450 What Is Aptensio XR? Aptensio XR is a prescription central nervous system (CNS) stimulant containing methylphenidate hydrochloride in an extended-release capsule formulation. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. Aptensio XR uses a unique multilayer bead technology to deliver an initial immediate dose of methylphenidate followed by a sustained release throughout the day. This means patients typically only... ### Arazlo **Generic:** tazarotene Findability: 45/100 | Shortage: active | Insurance: $0–$60 | Cash: $564–$683 What Is Arazlo? Arazlo is the brand name for tazarotene 0.045% lotion, a prescription topical retinoid approved by the FDA on December 19, 2019. It is manufactured by Ortho Dermatologics, a division of Bausch Health Companies Inc. Arazlo was the first tazarotene acne treatment available in lotion form. Arazlo is FDA-approved for the topical treatment of acne vulgaris in patients 9 years of age and older. It treats both inflammatory lesions (papules, pustules, nodules) and non-inflammatory... ### Arimidex **Generic:** anastrozole Findability: 85/100 | Insurance: $0–$30 | Cash: $10–$258 What Is Arimidex (Anastrozole)? Arimidex is the brand name for anastrozole, a non-steroidal aromatase inhibitor (NSAI) used to treat hormone receptor-positive breast cancer in postmenopausal women. First approved by the FDA in 1995, it has been one of the most-studied medications in oncology and remains a cornerstone of endocrine therapy for breast cancer. Anastrozole is available as a white 1 mg film-coated tablet, taken orally once daily with or without food. Generic anastrozole has been... ### Armodafinil **Generic:** Armodafinil Findability: 65/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $30–$400 What Is Armodafinil? Armodafinil (brand name Nuvigil) is a wakefulness-promoting medication used to treat excessive sleepiness caused by narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD). It is the R-enantiomer of Modafinil (Provigil), meaning it contains only the more pharmacologically active half of the Modafinil molecule. Armodafinil is taken once daily — in the morning for narcolepsy and OSA, or about one hour before your shift for shift work disorder. It can... ### Arthriten Inflammatory Pain Formula **Generic:** acetaminophen, aspirin, and caffeine Findability: 62/100 | Insurance: $0 | Cash: $11–$14 What Is Arthriten Inflammatory Pain Formula? Arthriten Inflammatory Pain Formula is a maximum-strength over-the-counter (OTC) analgesic combination product manufactured by Alva-Amco, a U.S.-based specialty non-prescription pharmaceutical company. It is available in coated film caplets called SpeedCaps and requires no prescription. Each caplet contains three active ingredients: acetaminophen 250 mg (analgesic and antipyretic), aspirin 250 mg (NSAID/anti-inflammatory), and caffeine anhydrous 65... ### Ashlyna 91 Day **Generic:** Ashlyna 91 Day Findability: 60/100 | Shortage: monitoring | Insurance: $0–$0 | Cash: $20–$400 What Is Ashlyna 91 Day? Ashlyna 91 Day is an extended-cycle combination hormonal oral contraceptive used to prevent pregnancy. It contains two hormones — Levonorgestrel (a synthetic progestin) and Ethinyl Estradiol (a synthetic estrogen). Unlike traditional 28-day birth control packs, Ashlyna uses a 91-day cycle, meaning you take active pills for 84 consecutive days followed by 7 days of low-dose estrogen pills. This extended-cycle design reduces the number of periods you have to approximately... ### Astagraf XL **Generic:** tacrolimus Findability: 55/100 | Insurance: $0-$50 | Cash: $95-$880 What Is Astagraf XL? Astagraf XL is the brand name for tacrolimus extended-release capsules, manufactured by Astellas Pharma US. It was FDA-approved on July 19, 2013, making it the first once-daily oral tacrolimus formulation approved in the United States. It is available in 0.5 mg, 1 mg, and 5 mg strengths. Astagraf XL is a calcineurin inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in adult and pediatric kidney transplant patients who can swallow capsules, used... ### Atacand **Generic:** candesartan Findability: 80/100 | Insurance: $5–$30 | Cash: $23–$155 What Is Atacand? Atacand is the brand name for candesartan (candesartan cilexetil), an angiotensin II receptor blocker (ARB) approved by the FDA in June 1998. It is manufactured by AstraZeneca and Takeda Pharmaceuticals and is also widely available as generic candesartan from multiple manufacturers including Alembic Pharmaceuticals, Sandoz, and Zydus. Atacand is FDA-approved to treat high blood pressure (hypertension) in adults and children ages 1 to 16 years, and to treat heart failure (NYHA... ### Atogepant **Generic:** atogepant Findability: 55/100 | Insurance: $0–$300 | Cash: $1,185–$1,600 What Is Atogepant? Atogepant is the generic name for Qulipta, a prescription oral tablet manufactured by AbbVie Inc. It belongs to a class of drugs called CGRP receptor antagonists — also known as gepants. The FDA first approved atogepant in September 2021 for the preventive treatment of episodic migraine in adults, and expanded the indication to include chronic migraine prevention in March 2023. Unlike older migraine preventives that were originally developed for other conditions, atogepant... ### Atropine **Generic:** Atropine Findability: 45/100 | Shortage: active | Insurance: $0–$25 | Cash: $20–$800+ What Is Atropine? Atropine (Atropine Sulfate) is an anticholinergic medication that has been used in medicine for decades. It is FDA-approved for treating symptomatic bradycardia (abnormally slow heart rate), organophosphate and nerve agent poisoning, reducing salivary and bronchial secretions before surgery, and producing cycloplegia and mydriasis (pupil dilation) for ophthalmic examinations. In ophthalmology, it is also used to treat amblyopia (lazy eye) in children. Atropine is... ### Atzumi **Generic:** dihydroergotamine mesylate Findability: 45/100 | Insurance: Varies widely | Cash: $900–$1,200+ What Is Atzumi? Atzumi is a prescription migraine medication containing dihydroergotamine mesylate (DHE), an ergot alkaloid with over 70 years of use in migraine treatment. It was FDA-approved on April 30, 2025, and is manufactured by Satsuma Pharmaceuticals, Inc. (Durham, NC). Atzumi is the first and only DHE nasal powder — a drug-device combination that delivers DHE in dry powder form directly to the nasal mucosa for rapid systemic absorption. Atzumi is indicated for the acute treatment of... ### Augmentin **Generic:** Augmentin Findability: 50/100 | Shortage: active | Insurance: $5–$45 | Cash: $9–$97 What Is Augmentin? Augmentin is a prescription antibiotic that combines Amoxicillin (a penicillin-type antibiotic) with Clavulanate Potassium (a beta-lactamase inhibitor). It is manufactured by GlaxoSmithKline (GSK) and is widely available as a generic. Augmentin is FDA-approved to treat a range of bacterial infections including: Lower respiratory tract infections Acute bacterial sinusitis Acute otitis media (middle ear infections) Skin and skin structure infections Urinary tract... ### Aurovela Fe 1/20 28 Day **Generic:** Aurovela Fe 1/20 28 Day Findability: 55/100 | Shortage: monitoring | Insurance: $0–$10 | Cash: $8–$49 What Is Aurovela Fe 1/20 28 Day? Aurovela Fe 1/20 28 Day is a combination oral contraceptive (birth control pill) manufactured by Aurobindo Pharma. It is a generic equivalent of the brand-name drug Loestrin Fe 1/20. Each 28-day pack contains: 21 active tablets with norethindrone acetate (1 mg) and ethinyl estradiol (20 mcg) — synthetic versions of the hormones progesterone and estrogen 7 non-hormone tablets containing ferrous fumarate (75 mg of iron), taken during the placebo week to... ### Azstarys **Generic:** Azstarys Findability: 55/100 | Shortage: monitoring | Insurance: $0–$60 | Cash: $350–$571 What Is Azstarys? Azstarys is a once-daily prescription stimulant medication approved by the FDA for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 and older. It is manufactured by Corium, a Sun Pharmaceutical company. Azstarys combines two active ingredients: serdexmethylphenidate (SDX), a prodrug that slowly converts into dexmethylphenidate in the body, and immediate-release dexmethylphenidate (d-MPH). This unique prodrug design provides both rapid onset... ### Bactroban **Generic:** mupirocin Findability: 88/100 | Insurance: $0–$15 | Cash: $15–$40 What Is Bactroban? Bactroban is the brand name for mupirocin, a topical antibiotic first approved by the FDA in 1997. It is one of the most commonly prescribed topical antibiotics in the United States, used primarily to treat impetigo — a highly contagious bacterial skin infection most common in children — and secondarily infected traumatic skin lesions. Bactroban is available in three formulations: a 2% ointment (for impetigo), a 2% cream (for infected skin wounds), and a 2% nasal ointment... ### Banophen Cream **Generic:** diphenhydramine hydrochloride topical Findability: 82/100 | Insurance: $0–$15 | Cash: $5–$15 What Is Banophen Cream? Banophen Cream is a brand-name over-the-counter (OTC) topical antihistamine cream. Its active ingredient is diphenhydramine hydrochloride — the same antihistamine found in Benadryl. Applied directly to the skin, it temporarily relieves pain and itching from insect bites, minor burns, sunburn, minor skin irritations, and rashes from poison ivy, poison oak, or poison sumac. Banophen Cream is available in 1% and 2% diphenhydramine HCl concentrations, sometimes combined... ### Baqsimi **Generic:** glucagon Findability: 75/100 | Insurance: $0–$50 | Cash: $300–$401 What Is Baqsimi? Baqsimi (glucagon nasal powder 3 mg) is the first and only nasally administered glucagon rescue treatment approved by the FDA. It is used for the emergency treatment of severe hypoglycemia (dangerously low blood sugar) in adults and children ages 1 year and older with diabetes. Baqsimi was originally developed by Eli Lilly and received FDA approval on July 24, 2019. It is now manufactured and marketed by Amphastar Pharmaceuticals. The drug's approval was expanded in 2025 to... ### Basaglar **Generic:** insulin glargine Findability: 78/100 | Insurance: $0–$35 | Cash: $35–$327 What Is Basaglar? Basaglar (insulin glargine injection) is a long-acting basal insulin manufactured by Eli Lilly and Company. FDA-approved on December 16, 2015, Basaglar contains 100 units of insulin glargine per mL (U-100) and is delivered via the Basaglar KwikPen — a disposable, prefilled insulin pen. It is classified as a 'follow-on' insulin glargine product with the same amino acid sequence as Lantus (Sanofi), approved through its own 505(b)(2) clinical pathway. Basaglar is FDA-approved... ### Beclomethasone **Generic:** beclomethasone Findability: 55/100 | Insurance: $15–$75 | Cash: $196–$414 What Is Beclomethasone? Beclomethasone is a synthetic corticosteroid medication available in several forms: as an inhaled aerosol (Qvar RediHaler) for asthma maintenance, as a nasal spray (Beconase AQ, QNASL) for allergic rhinitis, and as a topical cream for inflammatory skin conditions. It has been prescribed for over 50 years and is a cornerstone of inhaled corticosteroid (ICS) therapy for asthma. The most commonly prescribed form in the United States is Qvar RediHaler — a breath-actuated... ### Belsomra **Generic:** Belsomra Findability: 72/100 | Insurance: $0–$75 | Cash: $450–$550 What is Belsomra and what does it do? Belsomra (Suvorexant) is a prescription sleep medication approved by the FDA for the treatment of insomnia in adults. It helps with both falling asleep and staying asleep throughout the night. Unlike older sleep medications that sedate you by enhancing GABA activity, Belsomra works by blocking your brain's wake signals, allowing sleep to occur more naturally. Belsomra is manufactured by Merck and has been available since 2014. It belongs to a newer class... ### Benadryl **Generic:** diphenhydramine Findability: 85/100 | Shortage: resolved | Insurance: $0–$10 | Cash: $3–$15 What Is Benadryl? Benadryl is the brand name for diphenhydramine hydrochloride, a first-generation H1 antihistamine that has been in clinical use since 1946. Manufactured by McNeil Consumer Healthcare (a Johnson & Johnson company), Benadryl is one of the most widely recognized over-the-counter medications in the United States. Diphenhydramine is also sold under brand names including ZzzQuil (P&G), Unisom SleepGels, Sominex, Diphenhist, and Nytol, as well as dozens of generic versions at every... ### Benicar **Generic:** Benicar Findability: 88/100 | Insurance: $0–$15 | Cash: $10–$350 What Is Benicar? Benicar is the brand name for Olmesartan Medoxomil, a prescription medication in the angiotensin II receptor blocker (ARB) drug class. It is FDA-approved to treat high blood pressure (hypertension) in adults and children aged 6 years and older. By lowering blood pressure, Benicar helps reduce the risk of heart attack, stroke, and kidney problems. It is taken once daily by mouth, with or without food, and is available as both brand-name Benicar and generic Olmesartan. ### Benzamycin **Generic:** erythromycin/benzoyl peroxide Findability: 78/100 | Insurance: $0–$30 | Cash: $31–$491 What Is Benzamycin? Benzamycin is a prescription topical gel used to treat acne vulgaris. It contains two active ingredients: erythromycin (3%), a macrolide antibiotic, and benzoyl peroxide (5%), an antibacterial and keratolytic agent. Together, they reduce acne-causing bacteria on the skin and help clear pores. Benzamycin is manufactured by Bausch Health US, LLC. A generic version — erythromycin/benzoyl peroxide 3%/5% topical gel — is also available from manufacturers including Rising... ### Benzonatate **Generic:** Benzonatate Findability: 82/100 | Insurance: $0–$15 | Cash: $4–$45 What Is Benzonatate? Benzonatate is a non-narcotic antitussive (cough suppressant) used to relieve coughs caused by colds, bronchitis, pneumonia, and other respiratory conditions. It was first approved by the FDA in 1958 and has been a staple cough treatment for decades. Unlike opioid-based cough suppressants like codeine, Benzonatate is not a controlled substance and does not carry the same risk of addiction or respiratory depression. The brand-name version is Tessalon Perles, though most... ### Benzphetamine **Generic:** Benzphetamine Findability: 60/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $70–$625 What is Benzphetamine and what does it do? Benzphetamine (brand names Didrex and Regimex) is a prescription weight-loss medication classified as a sympathomimetic amine anorectic. It is approved by the FDA as a short-term adjunct to caloric restriction for weight loss in patients with a BMI of 30 or higher who have not responded to diet and exercise alone. Benzphetamine works by suppressing appetite, making it easier to stick to a reduced-calorie diet. It is intended for use over a period of... ### Besivance **Generic:** besifloxacin Findability: 55/100 | Insurance: $0–$75 | Cash: $230–$350 What Is Besivance? Besivance (besifloxacin 0.6% ophthalmic suspension) is a brand-name prescription antibiotic eye drop manufactured by Bausch + Lomb. It was approved by the FDA on May 28, 2009, and is indicated for the treatment of bacterial conjunctivitis — commonly called pink eye — in adults and children aged 1 year and older. Besifloxacin is a fourth-generation fluoroquinolone antibiotic developed exclusively for ophthalmic use. Unlike systemic fluoroquinolones (such as ciprofloxacin or... ### Besremi **Generic:** Besremi Findability: 35/100 | Shortage: active | Insurance: $0–$150 | Cash: $9,700–$11,000 What Is Besremi? Besremi (Ropeginterferon Alfa-2b-njft) is a pegylated interferon alfa-2b biologic medication manufactured by PharmaEssentia Corporation. It is FDA-approved for the treatment of polycythemia vera (PV) in adults — a rare blood cancer where the bone marrow produces too many red blood cells, increasing the risk of blood clots, stroke, and heart attack. Besremi is the only interferon specifically FDA-approved for polycythemia vera. It is self-administered as a subcutaneous... ### Betamethasone **Generic:** betamethasone Findability: 82/100 | Insurance: $0–$25 | Cash: $13–$73 What Is Betamethasone? Betamethasone is a synthetic glucocorticoid (corticosteroid) used to reduce inflammation and suppress immune responses across a wide range of medical conditions. It belongs to the same class as prednisone and dexamethasone but is significantly more potent — approximately 25 times more anti-inflammatory than cortisol by weight. It was first patented in 1958 and has been approved in the United States since 1961. In 2023, betamethasone was the 280th most commonly... ### Bethanechol **Generic:** bethanechol Findability: 72/100 | Insurance: $0–$30 | Cash: $17–$130 What Is Bethanechol? Bethanechol chloride (formerly sold as Urecholine) is a cholinergic agonist — a prescription medication that mimics acetylcholine to stimulate smooth muscle contractions in the bladder and gastrointestinal tract. It is the only FDA-approved oral medication specifically indicated for nonobstructive urinary retention and neurogenic atony of the urinary bladder. First synthesized in 1935, bethanechol belongs to the parasympathomimetic drug class. It is available only in... ### Betoptic S **Generic:** betaxolol ophthalmic Findability: 45/100 | Insurance: $30–$150 | Cash: $362–$521 What Is Betoptic S? Betoptic S is the brand name for betaxolol hydrochloride ophthalmic suspension 0.25%, a prescription eye drop used to lower elevated intraocular pressure (IOP) in patients with chronic open-angle glaucoma or ocular hypertension. It is manufactured by Novartis and was first approved by the FDA in 1985. Betoptic S is classified as a cardioselective beta-1 adrenergic receptor blocker. The "S" in its name refers to the proprietary suspension formulation, which is significantly... ### Bexagliflozin **Generic:** bexagliflozin Findability: 50/100 | Insurance: $0–$50 | Cash: $48–$70 What Is Bexagliflozin (Brenzavvy)? Bexagliflozin, sold under the brand name Brenzavvy, is a prescription medication approved by the FDA on January 23, 2023. It is manufactured by TheracosBio and belongs to the SGLT2 inhibitor drug class — the same class as Jardiance (empagliflozin), Farxiga (dapagliflozin), and Invokana (canagliflozin). It is FDA-approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is not approved for type 1... ### Bisacodyl **Generic:** bisacodyl Findability: 72/100 | Shortage: active | Insurance: $0 | Cash: $2–$15 What Is Bisacodyl? Bisacodyl is a stimulant laxative used for the temporary relief of occasional constipation and for cleansing the colon before colonoscopies and surgical procedures. It belongs to the diphenylmethane chemical family and is available over the counter without a prescription. Most people recognize bisacodyl by its most well-known brand name, Dulcolax, though it is also sold as Correctol, Fleet, Bisac-Evac, and many store-brand generics. Bisacodyl comes in three main forms:... ### Blis-To-Sol Powder **Generic:** undecylenic acid topical Findability: 72/100 | Insurance: $0 | Cash: $8–$15 What Is Blis-To-Sol Powder? Blis-To-Sol Powder is an over-the-counter topical antifungal medication manufactured by Oakhurst Co. Its active ingredient is undecylenic acid (with zinc undecylenate in the powder formulation) — a naturally derived fatty acid with proven antifungal properties. It is classified in the drug class of topical antifungals. Blis-To-Sol Powder is used to treat and prevent fungal skin infections including athlete's foot (tinea pedis), jock itch (tinea cruris), and... ### Blujepa **Generic:** Blujepa Findability: 60/100 | Shortage: monitoring | Insurance: $30–$75 | Cash: $400–$600 What Is Blujepa? Blujepa (Gepotidacin) is a first-in-class triazaacenaphthylene antibiotic manufactured by GSK. It was approved by the FDA in March 2025 for treating uncomplicated urinary tract infections (uUTIs) in female patients aged 12 and older (weighing at least 40 kg). In December 2025, it also received approval for uncomplicated urogenital gonorrhea in patients with limited or no alternative treatment options. Blujepa represents an entirely new class of antibiotics, offering an... ### Brexafemme **Generic:** Brexafemme Findability: 15/100 | Shortage: active | Insurance: $30–$150 | Cash: $450–$600 What Is Brexafemme? Brexafemme (Ibrexafungerp) is a first-in-class triterpenoid antifungal medication manufactured by Scynexis, Inc. and licensed to GSK for commercialization. It is FDA-approved for the treatment of vulvovaginal candidiasis (VVC) — commonly known as vaginal yeast infections — in adult and postmenarchal pediatric females. Brexafemme is also approved for the reduction in the incidence of recurrent vulvovaginal candidiasis (RVVC), making it the first oral non-azole treatment... ### Breztri Aerosphere **Generic:** budesonide/glycopyrrolate/formoterol fumarate Findability: 65/100 | Insurance: $0–$200 | Cash: $572–$930 What Is Breztri Aerosphere? Breztri Aerosphere is a prescription triple-combination inhaler made by AstraZeneca that combines three medications — budesonide (an inhaled corticosteroid/ICS), glycopyrrolate (a long-acting muscarinic antagonist/LAMA), and formoterol fumarate (a long-acting beta2-adrenergic agonist/LABA) — in a single pressurized metered-dose inhaler. First approved by the FDA in July 2020 for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults,... ### Brinzolamide **Generic:** brinzolamide Findability: 65/100 | Insurance: $10–$45 | Cash: $53–$309 What Is Brinzolamide? Brinzolamide is a prescription ophthalmic medication used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It is sold under the brand name Azopt (manufactured by Alcon) and is available as a generic suspension from multiple manufacturers including Sandoz, Bausch & Lomb, and Teva. Generic brinzolamide became available in the U.S. in 2021. Brinzolamide belongs to the drug class known as carbonic anhydrase inhibitors... ### Briviact **Generic:** Briviact Findability: 55/100 | Shortage: monitoring | Insurance: $10–$150 | Cash: $1,500–$2,000 What Is Briviact? Briviact (Brivaracetam) is a prescription anticonvulsant medication manufactured by UCB, Inc. It is FDA-approved as adjunctive therapy for partial-onset (focal) seizures in patients 1 month of age and older. This means Briviact is used alongside other seizure medications to help reduce the frequency of focal seizures. Briviact is a racetam derivative and a chemical analog of Levetiracetam (Keppra), but it binds to its target — synaptic vesicle glycoprotein 2A (SV2A) — with... ### Bromocriptine **Generic:** bromocriptine Findability: 68/100 | Insurance: $0–$50 | Cash: $8–$160 What Is Bromocriptine? Bromocriptine is an ergot-derived dopamine D2 receptor agonist that has been in medical use since 1975. It is sold under two brand names in the United States: Parlodel (tablets and capsules, for hyperprolactinemia, Parkinson's disease, and acromegaly) and Cycloset (quick-release tablets for type 2 diabetes). Generic bromocriptine mesylate is available as the Parlodel formulation; Cycloset has no generic equivalent. Bromocriptine's four FDA-approved indications are... ### Bronchitol **Generic:** mannitol Findability: 72/100 | Insurance: $100–$500 | Cash: $3,800–$3,900 What Is Bronchitol? Bronchitol (mannitol inhalation powder) is an FDA-approved specialty medication used as add-on maintenance therapy to improve pulmonary function in adults 18 years of age and older with cystic fibrosis (CF). It was first approved by the FDA on October 30, 2020, making it the first inhaled dry powder mucoactive agent approved for CF in nearly 30 years. Bronchitol is developed by Pharmaxis Ltd. and distributed in the United States exclusively by Chiesi USA, Inc. It comes as... ### Bumetanide **Generic:** bumetanide Findability: 62/100 | Shortage: resolved | Insurance: $0–$15 | Cash: $10–$80 What Is Bumetanide? Bumetanide (brand name Bumex) is a potent loop diuretic — commonly called a "water pill" — used to treat fluid retention (edema) in patients with heart failure, liver disease, and kidney disease including nephrotic syndrome. It is FDA-approved for these conditions and is available as an inexpensive generic manufactured by multiple pharmaceutical companies. Bumetanide is approximately 40 to 60 times more potent than furosemide (Lasix) on a milligram-per-milligram basis,... ### Bupivacaine **Generic:** Bupivacaine Findability: 3/100 | Shortage: active | Insurance: $0–$50 | Cash: $5–$40 What Is Bupivacaine? Bupivacaine is a long-acting amide-type local anesthetic used to numb specific areas of the body during and after surgical procedures. It is one of the most widely used injectable anesthetics in hospitals and surgical centers worldwide. Healthcare providers use Bupivacaine for epidural anesthesia during labor and delivery, spinal anesthesia for surgery, peripheral nerve blocks, dental procedures, and local wound infiltration. The brand-name liposomal formulation Exparel... ### Buprenorphine **Generic:** Buprenorphine Findability: 45/100 | Shortage: active | Insurance: $5–$50 | Cash: $45–$600 What Is Buprenorphine? Buprenorphine is a partial opioid agonist that is FDA-approved for the treatment of opioid use disorder (OUD) and chronic pain. It is one of the most effective medications available for helping people overcome opioid addiction, reducing cravings and withdrawal symptoms while having a lower risk of overdose compared to full opioid agonists like Methadone. Buprenorphine is available under several brand names, including Suboxone (combined with Naloxone), Subutex,... ### Buprenorphine/Naloxone **Generic:** Buprenorphine/Naloxone Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $40–$600 What Is Buprenorphine/Naloxone? Buprenorphine/Naloxone is a prescription combination medication used to treat opioid use disorder (OUD). It is FDA-approved for opioid detoxification and long-term maintenance therapy, helping patients reduce cravings and withdrawal symptoms so they can focus on recovery. The medication is available as a sublingual film (placed under the tongue), sublingual tablet, or buccal film (placed against the cheek). Brand names include Suboxone, Zubsolv, and Bunavail,... ### Bupropion **Generic:** Bupropion Findability: 78/100 | Insurance: $0–$25 | Cash: $5–$150 What Is Bupropion? Bupropion is an aminoketone antidepressant classified as a norepinephrine-dopamine reuptake inhibitor (NDRI). It is one of the most widely prescribed antidepressants in the United States, ranking among the top 20 most prescribed medications. Bupropion is FDA-approved to treat Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD) (as Wellbutrin XL), and smoking cessation (as Zyban). It is also used off-label for ADHD, antidepressant-induced sexual dysfunction,... ### Bupropion XR **Generic:** Bupropion XR Findability: 70/100 | Shortage: monitoring | Insurance: $0–$30 | Cash: $15–$150 What Is Bupropion XR? Bupropion XR (extended-release) is an antidepressant that belongs to the norepinephrine-dopamine reuptake inhibitor (NDRI) class. It is FDA-approved for treating Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). Unlike most antidepressants, Bupropion works on dopamine and norepinephrine rather than serotonin, which gives it a unique side effect profile — it is less likely to cause weight gain or sexual dysfunction. Bupropion is also prescribed... ### Butabarbital **Generic:** butabarbital Findability: 8/100 | Shortage: active | Insurance: Not covered | Cash: $50–$150 What Is Butabarbital? Butabarbital (brand name Butisol Sodium, also known as secbutabarbital) is a prescription barbiturate medication classified as a central nervous system (CNS) depressant. It was FDA-approved for the short-term treatment of insomnia, daytime anxiety and sedation, and as a pre-surgical sedative. Butabarbital is a DEA Schedule III controlled substance due to its moderate-to-high potential for physical and psychological dependence. Butabarbital has been commercially... ### Calcitriol **Generic:** Calcitriol Findability: 75/100 | Insurance: $0–$15 | Cash: $10–$60 What Is Calcitriol? Calcitriol is the biologically active form of vitamin D, also known as 1,25-dihydroxyvitamin D3. Unlike over-the-counter vitamin D supplements that need to be converted by the liver and kidneys, Calcitriol is already in its active form and works immediately in the body. Calcitriol is FDA-approved to treat hypocalcemia (low blood calcium) in patients on chronic kidney dialysis, secondary hyperparathyroidism in chronic kidney disease, and hypocalcemia from... ### Calcium Acetate **Generic:** calcium acetate Findability: 82/100 | Insurance: $0–$20 | Cash: $26–$134 What Is Calcium Acetate? Calcium acetate is an FDA-approved prescription medication used to treat hyperphosphatemia — high levels of phosphate in the blood — in patients with end-stage renal disease (ESRD) who are on dialysis. The FDA first approved it in December 1990. It is sold under the brand names PhosLo, Phoslyra, Eliphos, and Calphron, as well as as a widely available generic. Calcium acetate belongs to the drug class known as phosphate binders (Minerals and electrolytes). It is... ### Caplyta **Generic:** Caplyta Findability: 55/100 | Shortage: monitoring | Insurance: $15–$150 | Cash: $1,650–$1,800 What Is Caplyta? Caplyta (lumateperone) is an atypical antipsychotic medication manufactured by Intra-Cellular Therapies, now part of Johnson & Johnson. It is FDA-approved for: Schizophrenia in adults Bipolar depression (depressive episodes associated with bipolar I or II disorder) as monotherapy or adjunctive therapy with lithium or valproate in adults Major depressive disorder (MDD) as adjunctive therapy with antidepressants in adults (approved November 2025) Caplyta is taken as a... ### Carbamazepine **Generic:** Carbamazepine Findability: 80/100 | Insurance: $0–$15 | Cash: $4–$80 What Is Carbamazepine? Carbamazepine is an anticonvulsant and mood-stabilizing medication that has been used for decades to treat several neurological and psychiatric conditions. It is FDA-approved for: Epilepsy — including partial seizures with complex symptomatology, generalized tonic-clonic seizures, and mixed seizure patterns Trigeminal neuralgia — severe facial nerve pain Bipolar disorder — acute manic and mixed episodes (marketed as Equetro for this indication) Carbamazepine is sold... ### Carbocaine With Neo-Cobefrin **Generic:** mepivacaine hydrochloride and levonordefrin Findability: 62/100 | Shortage: resolved | Insurance: $0 patient cost | Cash: $75–$150/box What Is Carbocaine With Neo-Cobefrin? Carbocaine 2% with Neo-Cobefrin is a brand-name combination dental anesthetic containing mepivacaine hydrochloride 2% (the local anesthetic) and levonordefrin 1:20,000 (the vasoconstrictor). It is manufactured by Septodont, Inc. and supplied in 1.7 mL single-dose dental cartridges, 50 per box. This medication is intended exclusively for dental use and is administered by injection — by infiltration or nerve block — to produce local anesthesia during dental... ### Carboplatin **Generic:** carboplatin Findability: 20/100 | Shortage: active | Insurance: $0–$50 | Cash: $8–$70 What Is Carboplatin? Carboplatin (brand name Paraplatin) is a platinum-based chemotherapy drug used to treat a wide range of cancers. It belongs to the alkylating agent class — drugs that interfere with cancer cell DNA to stop tumor growth. Carboplatin was patented in 1972 and received FDA approval in 1989, developed as a less toxic second-generation alternative to cisplatin. Carboplatin is FDA-approved for advanced ovarian carcinoma — both as first-line treatment (in combination with... ### Cartia XR **Generic:** Cartia XR Findability: 82/100 | Insurance: $0–$15 | Cash: $10–$70 What Is Cartia XR? Cartia XR is a brand name for Diltiazem Hydrochloride Extended-Release, a prescription medication used to treat high blood pressure (hypertension) and chronic stable angina (chest pain) in adults. It belongs to the calcium channel blocker drug class and is taken once daily as an extended-release capsule. By lowering blood pressure, Cartia XR helps reduce the risk of heart attack, stroke, and kidney problems. For patients with angina, it helps reduce the frequency and... ### Carvedilol **Generic:** Carvedilol Findability: 70/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $4–$90 What Is Carvedilol? Carvedilol is a non-cardioselective beta blocker with additional alpha-1 blocking activity. It is FDA-approved to treat heart failure (NYHA Class II–IV), hypertension (high blood pressure), and left ventricular dysfunction following a heart attack in clinically stable patients. Originally marketed as Coreg by GlaxoSmithKline, Carvedilol is now available as an affordable generic from manufacturers including Teva, Aurobindo, Zydus, and Sun Pharma. It is also used off-label... ### Cataflam **Generic:** diclofenac potassium Findability: 82/100 | Shortage: resolved | Insurance: $0–$30 | Cash: $15–$75 What Is Cataflam? Cataflam is the brand name for diclofenac potassium 50 mg immediate-release tablets, a prescription nonsteroidal anti-inflammatory drug (NSAID). It belongs to the same drug class as ibuprofen and naproxen, working by blocking cyclooxygenase (COX-1 and COX-2) enzymes to reduce the production of prostaglandins — compounds that cause pain, fever, and inflammation. The brand-name Cataflam (originally manufactured by Novartis) has been discontinued in the United States. However,... ### Caverject **Generic:** alprostadil Findability: 55/100 | Shortage: resolved | Insurance: $0–$50 | Cash: $220–$1,058 What Is Caverject? Caverject is a brand name for alprostadil, a synthetic form of Prostaglandin E1 (PGE1) that is injected directly into the corpus cavernosum of the penis to produce an erection. It has been FDA-approved for the treatment of erectile dysfunction (ED) since 1981, making it one of the longest-established injectable ED therapies available. Alprostadil is the only FDA-approved intracavernosal injection for erectile dysfunction. Caverject is primarily prescribed for men with ED... ### Cefaclor XR **Generic:** cefaclor Findability: 55/100 | Insurance: $5–$30 | Cash: $41–$275 What Is Cefaclor XR? Cefaclor XR is the extended-release formulation of cefaclor, a second-generation cephalosporin antibiotic. It comes as a 500 mg film-coated tablet taken twice daily with food. The drug is classified as a semisynthetic beta-lactam antibiotic with bactericidal activity against a broad spectrum of gram-positive and gram-negative bacteria. Originally marketed under the brand name Ceclor CD by Eli Lilly and later as Raniclor, the brand versions have been discontinued. Generic... ### Cefazolin **Generic:** Cefazolin Findability: 55/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $5–$30 What Is Cefazolin? Cefazolin (formerly branded as Ancef and Kefzol) is a first-generation cephalosporin antibiotic given by injection (IV or IM). It is one of the most commonly used antibiotics in hospitals, prescribed to treat a wide range of bacterial infections including respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections, bloodstream infections (septicemia), and endocarditis. Cefazolin is also the go-to antibiotic for surgical... ### Cefpodoxime **Generic:** Cefpodoxime Findability: 82/100 | Insurance: $0–$15 | Cash: $15–$174 What Is Cefpodoxime? Cefpodoxime (brand name Vantin, now discontinued) is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It is FDA-approved for acute otitis media (ear infections), pharyngitis, tonsillitis, community-acquired pneumonia, acute bronchitis exacerbations, sinusitis, uncomplicated urinary tract infections, uncomplicated gonorrhea, and skin infections. It is available as a generic medication from several manufacturers including... ### Celestone Soluspan **Generic:** betamethasone sodium phosphate and betamethasone acetate Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $22–$117 What Is Celestone Soluspan? Celestone Soluspan is the brand name for betamethasone sodium phosphate and betamethasone acetate injectable suspension, a combination corticosteroid medication used to reduce inflammation and suppress the immune response across a wide range of medical conditions. It contains two forms of betamethasone: a rapidly absorbed soluble salt (sodium phosphate) for fast onset of action, and a slowly absorbed depot salt (acetate) for sustained, long-lasting... ### CellCept **Generic:** mycophenolate mofetil Findability: 55/100 | Shortage: active | Insurance: $0–$88 | Cash: $25–$1,765 What Is CellCept? CellCept is the brand name for mycophenolate mofetil (MMF), an immunosuppressant manufactured by Genentech (a Roche company). It is FDA-approved to prevent organ rejection in patients who have received a kidney, heart, or liver transplant, and to prevent graft-versus-host disease after hematopoietic stem cell transplantation. Generic versions of mycophenolate mofetil are available from multiple manufacturers. CellCept belongs to the class of selective immunosuppressants and... ### Cepacol Antibacterial Mouthwash **Generic:** Cepacol Antibacterial Mouthwash Findability: 55/100 | Shortage: monitoring | Insurance: $6–$10 | Cash: $6–$10 What Is Cepacol Antibacterial Mouthwash? Cepacol Antibacterial Mouthwash is an over-the-counter (OTC) oral antiseptic rinse containing Cetylpyridinium Chloride (CPC) 0.05% as its active ingredient. It belongs to the quaternary ammonium antiseptic class and is manufactured by RB Health (Reckitt Benckiser). Cepacol is the #1 mouthwash brand used in hospitals and is designed to: Help prevent and reduce plaque that leads to gingivitis Reduce bleeding gums associated with early gum disease Kill... ### Cepastat Sore Throat & Cough **Generic:** Cepastat Sore Throat & Cough Findability: 30/100 | Shortage: active | Insurance: $0–$5 | Cash: $5–$10 What Is Cepastat Sore Throat & Cough? Cepastat Sore Throat & Cough is an over-the-counter combination lozenge designed to temporarily relieve minor sore throat pain and suppress cough. Each sugar-free cherry-flavored lozenge contains three active ingredients: Benzocaine (6 mg) as a local anesthetic, Dextromethorphan HBr (5 mg) as a cough suppressant, and Menthol (10 mg) for cooling relief and additional pain relief. It is manufactured by Insight Pharmaceuticals LLC and is approved for treating... ### Chantix **Generic:** varenicline Findability: 82/100 | Shortage: resolved | Insurance: $0–$50 | Cash: $27–$630 What Is Chantix (Varenicline)? Chantix is the brand name for varenicline, a prescription medication FDA-approved in May 2006 to help adults quit smoking. Developed by Pfizer, it was the first oral non-nicotine prescription smoking cessation medication approved by the FDA since bupropion in 1997. It belongs to the drug class of nicotinic acetylcholine receptor partial agonists. Brand-name Chantix was recalled in June 2021 due to nitrosamine contamination, and generic varenicline has been the... ### Chlorthalidone **Generic:** chlorthalidone Findability: 82/100 | Insurance: $0–$30 | Cash: $7–$46 What Is Chlorthalidone? Chlorthalidone is a prescription thiazide-like diuretic (water pill) used to treat high blood pressure (hypertension) and fluid retention (edema). It has been FDA-approved since 1960 and is considered a first-line treatment for hypertension by major cardiology guidelines. Chlorthalidone is available as generic tablets in 12.5 mg, 25 mg, and 50 mg strengths. It is also available under the brand names Thalitone and Hemiclor, though most prescriptions are filled as... ### Chlorthalidone/Clonidine **Generic:** chlorthalidone/clonidine Findability: 10/100 | Shortage: active | Insurance: $0–$20 | Cash: N/A (discontinued) What Is Chlorthalidone/Clonidine (Clorpres)? Chlorthalidone/clonidine — sold under the brand name Clorpres — was a fixed-dose combination antihypertensive medication that paired two blood pressure drugs into a single oral tablet. It was FDA-approved for the treatment of hypertension (high blood pressure) in adults who had already been individually titrated on both component medications. The combination included clonidine hydrochloride (a centrally acting alpha-2 adrenergic agonist) and... ### Chorionic Gonadotropin **Generic:** Chorionic Gonadotropin Findability: 35/100 | Shortage: active | Insurance: $30–$100 | Cash: $266–$465 What Is Chorionic Gonadotropin? Chorionic Gonadotropin (HCG) is a naturally occurring hormone that is produced during pregnancy. The pharmaceutical version is classified as a gonadotropin and is used for several important medical purposes. In women, it is used to trigger ovulation as part of fertility treatments, including in vitro fertilization (IVF). In men, it treats hypogonadotropic hypogonadism by stimulating the testes to produce testosterone. It is also used in prepubertal boys with... ### Cibinqo **Generic:** abrocitinib Findability: 45/100 | Insurance: $0–$500 | Cash: $6,000–$7,100 What Is Cibinqo? Cibinqo is the brand name for abrocitinib, an oral prescription medication manufactured by Pfizer Inc. It belongs to the Janus kinase (JAK) inhibitor drug class — specifically, it is a selective JAK1 inhibitor. Cibinqo was FDA-approved on January 14, 2022, making it one of the newer oral treatments for moderate-to-severe atopic dermatitis (eczema) in the United States. Cibinqo is indicated for adults and adolescents 12 years of age and older with refractory,... ### Ciclesonide **Generic:** Ciclesonide Findability: 55/100 | Shortage: monitoring | Insurance: $15–$75 | Cash: $150–$420 What Is Ciclesonide? Ciclesonide is an inhaled corticosteroid used to treat persistent asthma and allergic rhinitis. It is sold under three brand names: Alvesco (oral inhaler for asthma), Omnaris (nasal spray for allergic rhinitis), and Zetonna (nasal aerosol for seasonal allergic rhinitis). Alvesco is approved for maintenance treatment of asthma in adults and children 12 years and older. Omnaris is approved for seasonal and perennial allergic rhinitis in patients 6 years and older. Zetonna... ### Ciclopirox **Generic:** ciclopirox Findability: 82/100 | Insurance: $0–$30 | Cash: $9–$151 What Is Ciclopirox? Ciclopirox is a broad-spectrum synthetic topical antifungal medication in the hydroxypyridone drug class. It is available in five formulations: cream (0.77%), gel (0.77%), shampoo (1%), topical suspension (0.77%), and nail lacquer solution (8%). Brand names include Penlac (nail lacquer), Loprox (cream and shampoo), and Ciclodan (nail solution), though most patients now use generic versions. Ciclopirox has been available in the United States since the mid-1980s and treats a... ### Cinacalcet **Generic:** cinacalcet Findability: 75/100 | Insurance: $0–$40 | Cash: $20–$800 What Is Cinacalcet? Cinacalcet (brand name: Sensipar) is a prescription oral medication in a drug class called calcimimetics. It was FDA-approved in 2004 — the first in its class — and is available as film-coated tablets in three strengths: 30 mg, 60 mg, and 90 mg. Generic versions became available in the United States around 2019, manufactured by multiple companies including Aurobindo Pharma. Cinacalcet is primarily prescribed to adult patients on dialysis who have secondary... ### Cipro XR **Generic:** ciprofloxacin extended-release Findability: 55/100 | Shortage: resolved | Insurance: $0–$15 | Cash: $8–$60 What Is Cipro XR? Cipro XR is the brand name for ciprofloxacin extended-release tablets, a once-daily fluoroquinolone antibiotic specifically approved for treating urinary tract infections (UTIs) and kidney infections (pyelonephritis) in adults aged 18 and older. The extended-release formulation delivers ciprofloxacin more slowly over 24 hours, allowing for convenient once-daily dosing. Important 2026 note: Brand-name Cipro XR (Bayer) has been discontinued. Generic ciprofloxacin... ### Ciprofloxacin/Fluocinolone **Generic:** ciprofloxacin and fluocinolone acetonide Findability: 60/100 | Insurance: $0–$60 | Cash: $257–$395 What Is Ciprofloxacin/Fluocinolone (Otovel)? Ciprofloxacin/fluocinolone — sold under the brand name Otovel — is a prescription combination ear drop that was FDA-approved on April 29, 2016. It combines ciprofloxacin hydrochloride 0.3% (a fluoroquinolone antibiotic) with fluocinolone acetonide 0.025% (a medium-strength corticosteroid) in a sterile, preservative-free otic solution. The medication is approved specifically for acute otitis media with tympanostomy tubes (AOMT) in pediatric patients... ### Citanest **Generic:** prilocaine Findability: 15/100 | Shortage: active | Insurance: $0–$50 (bundled with procedure) | Cash: N/A (dental office supply) What Is Citanest? Citanest is the brand name for prilocaine hydrochloride, an amide-type local anesthetic used exclusively in dentistry to numb the mouth before and during dental procedures. It belongs to the same chemical class as lidocaine, mepivacaine, and articaine — all of which block pain signals by preventing sodium from entering nerve cells. Citanest was available in two formulations: Citanest Plain Dental (4% prilocaine without a vasoconstrictor) and Citanest Forte Dental (4%... ### ClindaMax **Generic:** clindamycin phosphate Findability: 72/100 | Insurance: $0–$50 | Cash: $30–$850 What Is ClindaMax? ClindaMax is a brand-name prescription topical antibiotic gel containing clindamycin phosphate 1%. It belongs to the lincosamide antibiotic drug class and is FDA-approved for the treatment of acne vulgaris (common acne). When applied to the skin, it works by reducing the bacteria that cause inflammatory acne breakouts—specifically Cutibacterium acnes. ClindaMax is available only with a prescription and is not a controlled substance. Other topical clindamycin brands include... ### Clindamycin **Generic:** Clindamycin Findability: 6/100 | Shortage: active | Insurance: $0–$15 | Cash: $9–$109 What Is Clindamycin? Clindamycin is a lincosamide antibiotic used to treat a wide range of serious bacterial infections. Originally developed as a derivative of lincomycin, it has been a staple in medicine since its FDA approval. Clindamycin is prescribed for serious respiratory tract infections, skin and soft tissue infections, septicemia, intra-abdominal infections, bone and joint infections, and gynecological infections. The topical formulations are widely used for acne vulgaris, while... ### Clindesse **Generic:** clindamycin phosphate Findability: 65/100 | Insurance: $0–$50 | Cash: $109–$203 What Is Clindesse? Clindesse is the brand name for clindamycin phosphate 2% vaginal cream, manufactured by Padagis. It is a prescription antibiotic FDA-approved for the treatment of bacterial vaginosis (BV) in non-pregnant women. Unlike multi-day BV treatments, Clindesse is administered as a single dose — the complete contents of one pre-filled applicator inserted intravaginally. Bacterial vaginosis is the most common vaginal infection in women of reproductive age, occurring when the natural... ### Clinpro 5000 **Generic:** sodium fluoride Findability: 55/100 | Insurance: $0–$27 | Cash: $17–$27 What Is Clinpro 5000? Clinpro 5000 is a prescription-strength toothpaste manufactured by Solventum (formerly 3M ESPE) containing 1.1% sodium fluoride — 5,000 ppm of fluoride ion, compared to 1,000–1,450 ppm in standard over-the-counter toothpastes. It is indicated for use as part of a professional dental program for the prevention and control of dental caries (tooth decay). What makes Clinpro 5000 unique is its exclusive functionalized tri-calcium phosphate (fTCP) system. During... ### Clobex **Generic:** clobetasol propionate Findability: 45/100 | Shortage: active | Insurance: $0–$50 | Cash: $23–$461 What Is Clobex? Clobex is the brand name for clobetasol propionate 0.05%, a super-potent (Class I) topical corticosteroid manufactured by Galderma Laboratories. It is the most powerful category of topical steroid available in the United States. Clobex is available as a shampoo, lotion, and spray — all containing the same active ingredient at the same 0.05% concentration. Clobex Shampoo is FDA-approved for moderate to severe scalp psoriasis in adults 18 and older. The lotion and spray... ### Cloderm **Generic:** clocortolone pivalate Findability: 65/100 | Insurance: $20–$60 | Cash: $88–$450 What Is Cloderm? Cloderm is the brand name for clocortolone pivalate 0.1% cream, a mid-potency (Class 4) topical corticosteroid that has been FDA-approved since August 22, 1977. It is used to treat corticosteroid-responsive dermatoses — inflammatory skin conditions including atopic dermatitis (eczema), psoriasis vulgaris, contact dermatitis, and seborrheic dermatitis. Currently distributed by EPI Health, LLC, Cloderm is manufactured by DPT Laboratories. Cloderm is available as a 0.1% cream in... ### Clomiphene **Generic:** Clomiphene Findability: 65/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $30–$415 What Is Clomiphene? Clomiphene (brand names Clomid and Serophene) is a selective estrogen receptor modulator (SERM) used primarily to treat ovulatory dysfunction in women who want to become pregnant. It is one of the most commonly prescribed fertility medications and has been a first-line treatment for ovulation induction for decades. Clomiphene is FDA-approved for treating ovulatory dysfunction, including in women with polycystic ovary syndrome (PCOS). It is also widely used off-label in men... ### Clomipramine **Generic:** Clomipramine Findability: 55/100 | Shortage: monitoring | Insurance: $5–$25 | Cash: $15–$150 What Is Clomipramine and What Does It Do? Clomipramine (brand name Anafranil) is a tricyclic antidepressant (TCA) that is FDA-approved for treating obsessive-compulsive disorder (OCD) in patients aged 10 and older. It is widely regarded as one of the most effective medications for OCD and is often tried when first-line SSRIs have not provided adequate relief. Off-label, clomipramine is also used for depression, anxiety disorders, panic disorder, neuropathic pain, cataplexy associated with... ### Clonazepam **Generic:** Clonazepam Findability: 45/100 | Shortage: active | Insurance: $0–$15 | Cash: $8–$45 What Is Clonazepam? Clonazepam (brand name Klonopin) is a benzodiazepine medication FDA-approved to treat certain seizure disorders — including Lennox-Gastaut syndrome, akinetic seizures, and myoclonic seizures — as well as panic disorder with or without agoraphobia. It is also used off-label for generalized anxiety disorder, social anxiety disorder, restless legs syndrome, and REM sleep behavior disorder. Clonazepam is a Schedule IV controlled substance, meaning it has a recognized medical... ### Clorazepate **Generic:** Clorazepate Findability: 48/100 | Shortage: active | Insurance: $10–$40 | Cash: $29–$155 What Is Clorazepate? Clorazepate (brand name Tranxene) is a benzodiazepine medication FDA-approved for three conditions: anxiety disorders, partial seizures (as add-on therapy), and acute alcohol withdrawal. It belongs to the long-acting benzodiazepine class, meaning its effects last longer than many other benzodiazepines. Clorazepate is a prodrug — it is converted in the body to its active form, Nordiazepam, which has a half-life of approximately 2 days. This long duration of action can be... ### Cobenfy **Generic:** xanomeline and trospium chloride Findability: 62/100 | Insurance: $0–$50 | Cash: $1,850–$1,887 Cobenfy (xanomeline and trospium chloride) is a first-in-class oral prescription medication approved by the FDA on September 26, 2024 for the treatment of schizophrenia in adults. It represents the first new mechanism of action for schizophrenia in over 30 years and the first antipsychotic to work without blocking dopamine D2 receptors. Cobenfy combines xanomeline, a muscarinic M1/M4 receptor agonist, with trospium chloride, a peripherally acting muscarinic antagonist that prevents the GI and... ### Colestipol **Generic:** colestipol Findability: 78/100 | Shortage: resolved | Insurance: $5–$20 | Cash: $20–$60 What Is Colestipol? Colestipol (brand name Colestid) is a prescription medication in the bile acid sequestrant drug class. It is FDA-approved as an adjunct to diet and exercise for the reduction of elevated LDL cholesterol in adults with primary hypercholesterolemia. Colestipol is one of the oldest cholesterol-lowering drugs, first approved by the FDA in the 1960s, and remains a valuable option for patients who cannot tolerate statins or need additional LDL reduction. Unlike most cholesterol... ### Collagenase **Generic:** Collagenase Findability: 55/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $333–$7,222 What Is Collagenase? Collagenase is an enzymatic medication derived from the bacterium Clostridium histolyticum. It is available in two formulations for different medical uses: Santyl (topical ointment) is used for the debridement of chronic dermal ulcers and severely burned areas. It helps remove dead tissue from wounds while preserving healthy tissue, promoting natural healing. Xiaflex (injectable) is used to treat Dupuytren's contracture (a condition where thickened tissue in the hand... ### Combigan **Generic:** brimonidine tartrate/timolol maleate Findability: 72/100 | Insurance: $0–$30 | Cash: $20–$278 What Is Combigan? Combigan is a brand-name prescription eye drop that combines two active ingredients — brimonidine tartrate (0.2%) and timolol maleate (0.5%) — in a single bottle. It was developed by Allergan (now AbbVie) and received FDA approval in 2007. By 2020, it was the 256th most prescribed medication in the United States, with more than 1 million annual prescriptions. Combigan is used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular... ### Combogesic **Generic:** acetaminophen and ibuprofen Findability: 55/100 | Insurance: $0–$50 | Cash: $70–$120 What Is Combogesic? Combogesic is a prescription-only combination analgesic containing two active ingredients: acetaminophen and ibuprofen. It is manufactured by Hikma Pharmaceuticals USA Inc. under license from AFT Pharmaceuticals Limited of New Zealand. Combogesic is marketed internationally under the brand name Maxigesic, where it is approved in over 40 countries. Combogesic is available in two FDA-approved formulations: oral tablets (acetaminophen 325 mg / ibuprofen 97.5 mg per tablet,... ### Compazine **Generic:** prochlorperazine Findability: 45/100 | Shortage: active | Insurance: $0–$15 | Cash: $30–$200 What Is Compazine (Prochlorperazine)? Compazine is the brand name for prochlorperazine, a prescription medication in the phenothiazine drug class. Prochlorperazine has been used in the United States since the late 1950s, making it one of the longest-established antiemetic medications available. Today, the original Compazine brand has been discontinued, and the drug is sold exclusively as generic prochlorperazine — in tablets, rectal suppositories (sold as Compro), and injectable... ### Concerta **Generic:** Concerta Findability: 40/100 | Shortage: active | Insurance: $15–$40 | Cash: $37–$57 What Is Concerta? Concerta (methylphenidate extended-release) is a prescription stimulant medication used to treat ADHD in children (ages 6+), adolescents, and adults up to age 65. It is also used to treat narcolepsy. Manufactured by Janssen Pharmaceuticals, Concerta contains methylphenidate — the same active ingredient as Ritalin. What sets Concerta apart is its OROS delivery technology, providing once-daily dosing with consistent medication levels over 10–12 hours. Stimulant medications... ### Concerta XR **Generic:** Concerta XR Findability: 45/100 | Shortage: active | Insurance: $10–$45 | Cash: $30–$545 What Is Concerta XR? Concerta XR is a brand-name, extended-release form of Methylphenidate HCl, a central nervous system (CNS) stimulant. It is FDA-approved to treat Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older, including adults up to age 65. Concerta XR uses a unique OROS (Osmotic-controlled Release Oral delivery System) technology that delivers medication at a controlled rate over 10–12 hours, providing all-day symptom coverage with a single morning... ### Cosopt **Generic:** Cosopt Findability: 75/100 | Insurance: $0–$75 | Cash: $10–$220 What Is Cosopt? Cosopt is a prescription combination eye drop used to treat elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It combines two active ingredients — Dorzolamide (a carbonic anhydrase inhibitor) and Timolol (a beta-blocker) — into a single convenient drop. Cosopt is typically prescribed for patients who need more IOP reduction than a single medication can provide, or who haven't responded adequately to beta-blockers alone. It is also... ### Crinone **Generic:** Crinone Findability: 65/100 | Shortage: monitoring | Insurance: $30–$150 | Cash: $65–$700 What Is Crinone? Crinone is a prescription vaginal gel containing micronized progesterone, a naturally occurring female hormone essential for establishing and maintaining pregnancy. It is FDA-approved for two main uses: progesterone supplementation or replacement as part of Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency (Crinone 8%), and for the treatment of secondary amenorrhea (Crinone 4%). Crinone is also commonly used off-label for luteal... ### Cromolyn **Generic:** Cromolyn Findability: 30/100 | Shortage: active | Insurance: $30–$100 | Cash: $130–$400+ What Is Cromolyn? Cromolyn Sodium (brand name Gastrocrom) is a mast cell stabilizer used to treat systemic mastocytosis, mast cell activation syndrome (MCAS), and allergic conditions. It works by preventing mast cells from releasing inflammatory chemicals like histamine and leukotrienes. The oral solution is primarily prescribed for mastocytosis symptoms including diarrhea, flushing, headaches, abdominal pain, nausea, and itching. The nasal spray form (NasalCrom) is available over the counter... ### Cyanokit **Generic:** hydroxocobalamin Findability: 25/100 | Shortage: active | Insurance: Varies | Cash: $1,031–$1,146 What Is Cyanokit? Cyanokit is the brand name for hydroxocobalamin for injection — an FDA-approved emergency antidote for the treatment of known or suspected cyanide poisoning. It contains 5 grams of hydroxocobalamin, a form of vitamin B12, in a lyophilized (freeze-dried) powder that is reconstituted and administered intravenously. Cyanokit is not a medication dispensed at retail pharmacies — it is stocked by hospital emergency departments, advanced life support EMS agencies, and fire... ### Cyclogyl **Generic:** cyclopentolate Findability: 40/100 | Shortage: active | Insurance: $5–$20 | Cash: $10–$75 What Is Cyclogyl? Cyclogyl is the brand name for cyclopentolate hydrochloride, a prescription ophthalmic (eye drop) solution manufactured by Alcon Laboratories. It belongs to a drug class called anticholinergics, which work by blocking acetylcholine receptors in the eye. Generic cyclopentolate is also available from Sandoz and Bausch Health. Cyclogyl is FDA-approved to cause mydriasis (pupil dilation) and cycloplegia (temporary paralysis of the focusing muscles) in preparation for eye exams.... ### Cyproheptadine **Generic:** cyproheptadine Findability: 88/100 | Insurance: $0–$15 | Cash: $8–$66 What Is Cyproheptadine? Cyproheptadine hydrochloride is a first-generation antihistamine and serotonin antagonist that has been in clinical use since 1961. Originally marketed under the brand name Periactin (now discontinued in the U.S.), it is available today only as a generic medication. It is prescribed for a wide range of allergic conditions including seasonal and perennial allergic rhinitis, urticaria (hives), allergic conjunctivitis, cold urticaria, and dermatographism. Beyond its... ### Cytomel **Generic:** Cytomel Findability: 65/100 | Shortage: monitoring | Insurance: $10–$30 | Cash: $24–$300 What Is Cytomel? Cytomel is the brand name for Liothyronine Sodium, a synthetic form of triiodothyronine (T3), one of the two main thyroid hormones produced by the thyroid gland. It is manufactured by Pfizer and is classified as a thyroid hormone replacement medication. Cytomel is FDA-approved for: Replacement therapy in hypothyroidism — including primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) forms, whether congenital or acquired Adjunct to surgery and radioiodine... ### D.H.E. 45 **Generic:** dihydroergotamine mesylate Findability: 42/100 | Shortage: active | Insurance: $10–$60 | Cash: $262–$733 What Is D.H.E. 45? D.H.E. 45 is the brand name for dihydroergotamine mesylate injection — an ergot alkaloid used for the acute treatment of migraine headaches (with or without aura) and cluster headache episodes. It has been FDA-approved since 1946, making it one of the longest-used migraine medications in the United States. The original brand D.H.E. 45 by Bausch Health was discontinued in 2022. Generic versions of dihydroergotamine mesylate injection (1 mg/mL ampules) are still available... ### Dantrolene **Generic:** Dantrolene Findability: 60/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $50–$200 What Is Dantrolene? Dantrolene is a direct-acting skeletal muscle relaxant used to treat chronic muscle spasticity associated with conditions such as multiple sclerosis, cerebral palsy, spinal cord injuries, and stroke. Unlike other muscle relaxants that work in the brain or spinal cord, Dantrolene acts directly on the muscle fibers themselves. It is also the only FDA-approved treatment for malignant hyperthermia, a rare but life-threatening reaction to certain anesthesia drugs. Dantrolene is... ### Daptomycin **Generic:** Daptomycin Findability: 45/100 | Shortage: active | Insurance: $0–$150 | Cash: $29–$700 What Is Daptomycin? Daptomycin is a cyclic lipopeptide antibiotic used to treat serious infections caused by gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It was originally marketed under the brand name Cubicin by Merck & Co., though generic versions are now available from multiple manufacturers. Daptomycin is FDA-approved for: Complicated skin and skin structure infections (cSSSI) in adults and children Staphylococcus aureus bacteremia (bloodstream... ### Darifenacin XR **Generic:** Darifenacin XR Findability: 65/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $20–$350 What Is Darifenacin XR? Darifenacin XR (brand name Enablex) is a prescription medication used to treat overactive bladder (OAB). It helps reduce symptoms of urge urinary incontinence, urgency, and urinary frequency. Darifenacin belongs to a class of drugs called antimuscarinics (also known as anticholinergics). It is available as an extended-release tablet in 7.5 mg and 15 mg strengths, taken once daily. The brand-name version, Enablex, was originally manufactured by Novartis but has been... ### Dasatinib **Generic:** dasatinib Findability: 55/100 | Insurance: $0–$500 | Cash: $824–$891 What Is Dasatinib? Dasatinib is an oral prescription medication used to treat Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). It is sold under the brand name Sprycel by Bristol-Myers Squibb and is also available in generic form from manufacturers including Apotex, Teva, Lupin, Zydus, and Dr. Reddy's. The FDA first approved dasatinib in 2006. Dasatinib belongs to a class of medications called tyrosine kinase inhibitors (TKIs). It is... ### Daysee 91 Day **Generic:** Daysee 91 Day Findability: 62/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $27–$300 What Is Daysee 91 Day? Daysee 91 Day is an extended-cycle combination oral contraceptive manufactured by Lupin Pharmaceuticals. It is FDA-approved for the prevention of pregnancy in females of reproductive potential. Unlike traditional 28-day birth control packs, Daysee uses a 91-day cycle — you take 84 days of active hormone tablets followed by 7 days of low-dose estrogen tablets. This means you only have a period approximately four times per year instead of monthly. Daysee is also... ### Daytrana **Generic:** Daytrana Findability: 25/100 | Shortage: active | Insurance: N/A (discontinued) | Cash: $350–$500 (discontinued) What Is Daytrana? Daytrana is a transdermal patch that delivers Methylphenidate through the skin to treat Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 to 17. It was the only FDA-approved methylphenidate patch, offering an alternative for children who had difficulty swallowing pills or who experienced gastrointestinal side effects from oral formulations. The patch was applied to the hip area two hours before the desired effect and worn for up to nine hours before removal.... ### Dayvigo **Generic:** Dayvigo Findability: 72/100 | Insurance: $0–$30 | Cash: $135–$445 What Is Dayvigo? Dayvigo (lemborexant) is a prescription sleep medication used to treat insomnia in adults, manufactured by Eisai Inc. It was FDA-approved in December 2019 and is indicated for the treatment of insomnia characterized by difficulty with sleep onset and/or sleep maintenance. Dayvigo belongs to a class of medications called dual orexin receptor antagonists (DORAs) — a newer approach to treating insomnia that works differently from older sleep medications like benzodiazepines or... ### Decadron **Generic:** dexamethasone Findability: 72/100 | Shortage: active | Insurance: $0–$10 | Cash: $3–$36 What Is Decadron (Dexamethasone)? Decadron was the original brand name for dexamethasone, a synthetic corticosteroid (glucocorticoid) first synthesized in 1958. The Decadron brand tablet has been discontinued in the United States, but generic dexamethasone is widely available and actively prescribed across virtually every medical specialty. Dexamethasone appears on the World Health Organization's List of Essential Medicines and is one of the most widely prescribed anti-inflammatory agents in... ### Delsym XR **Generic:** dextromethorphan polistirex Findability: 90/100 | Insurance: $0 | Cash: $8–$20 What Is Delsym XR? Delsym XR is the brand name for dextromethorphan polistirex extended-release oral suspension — an over-the-counter cough suppressant (antitussive) manufactured by RB Health (US) LLC, a subsidiary of Reckitt Benckiser. It is available in grape and orange flavors in 3 fl oz and 5 fl oz bottles. The "XR" designation refers to its extended-release formulation, which provides up to 12 hours of cough suppression per dose. Unlike standard cough syrups that use dextromethorphan... ### Denorex Extra Strength **Generic:** salicylic acid topical Findability: 88/100 | Insurance: Not covered | Cash: $8–$15 What Is Denorex Extra Strength? Denorex Extra Strength is an over-the-counter (OTC) medicated 2-in-1 shampoo and conditioner used to treat dandruff, seborrheic dermatitis, and scalp psoriasis. No prescription is required. The current formulation — in use since August 2012 — contains 3% salicylic acid as its active ingredient, the maximum concentration available OTC in a shampoo. The product was originally formulated with coal tar as its active ingredient. In August 2012, coal tar was replaced... ### Depakote ER **Generic:** divalproex sodium Findability: 55/100 | Shortage: active | Insurance: $0–$30 | Cash: $20–$800 What Is Depakote ER? Depakote ER is the brand name for divalproex sodium extended-release tablets, manufactured by AbbVie. The "ER" stands for extended-release — the tablet is designed to release the active ingredient slowly over the day, enabling once-daily dosing. It was first FDA-approved in this extended-release formulation in 2000. Depakote ER is an anticonvulsant and mood-stabilizing medication classified in the valproate drug family. The active ingredient, divalproex sodium, is a... ### Depo-Estradiol **Generic:** estradiol cypionate Findability: 40/100 | Shortage: active | Insurance: $0–$50 | Cash: $30–$310 What Is Depo-Estradiol? Depo-Estradiol is the brand name for estradiol cypionate injection, an intramuscular hormone replacement therapy used to treat menopause symptoms, female hypoestrogenism due to hypogonadism, and — off-label — gender-affirming hormone therapy. The brand-name product was manufactured by Pfizer (Pharmacia & Upjohn) but has been discontinued. Compounded estradiol cypionate injection remains available through 503A and 503B compounding pharmacies. Estradiol cypionate is an... ### Depo-Medrol **Generic:** Depo-Medrol Findability: 65/100 | Shortage: monitoring | Insurance: $0–$30 | Cash: $6–$75 What Is Depo-Medrol? Depo-Medrol (Methylprednisolone Acetate) is an injectable corticosteroid manufactured by Pfizer. It is used to treat a wide range of inflammatory and autoimmune conditions, including rheumatoid arthritis, osteoarthritis, bursitis, severe allergic reactions, dermatologic diseases, and many other conditions where potent anti-inflammatory therapy is needed. Depo-Medrol is administered by a healthcare provider via intramuscular, intra-articular, soft tissue, or intralesional... ### Depo-Provera **Generic:** medroxyprogesterone acetate Findability: 78/100 | Insurance: $0–$30 | Cash: $55–$150 What Is Depo-Provera? Depo-Provera is the brand name for medroxyprogesterone acetate (MPA) injectable suspension, a synthetic progestin contraceptive given as an intramuscular injection once every 3 months (13 weeks). It is manufactured by Pfizer and has been FDA-approved for contraceptive use since 1992. Approximately 1 in 4 sexually active women in the United States has used the shot at some point. Generic versions (medroxyprogesterone acetate injection, 150 mg/mL) are FDA-approved and... ### Depo-SubQ Provera 104 **Generic:** medroxyprogesterone acetate Findability: 55/100 | Insurance: $0–$30 | Cash: $59–$100 What Is Depo-SubQ Provera 104? Depo-SubQ Provera 104 is the brand name for medroxyprogesterone acetate (MPA) 104 mg/0.65 mL injectable suspension, manufactured by Pfizer. It is a progestin-only hormonal medication given as a subcutaneous injection — injected just under the skin into the thigh or abdomen — every 12 to 14 weeks (approximately once every 3 months). Depo-SubQ Provera 104 is FDA-approved for two indications: prevention of pregnancy (contraception) and management of... ### Descovy **Generic:** Descovy Findability: 65/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $2,200–$2,944 What Is Descovy? Descovy is a prescription medication made by Gilead Sciences that contains two nucleoside reverse transcriptase inhibitors (NRTIs): emtricitabine and tenofovir alafenamide (TAF). It is FDA-approved for two main uses: HIV-1 Treatment: Used in combination with other antiretroviral medications to treat HIV-1 infection in adults and pediatric patients weighing at least 14 kg. Descovy is not a complete regimen on its own for HIV treatment. Pre-Exposure Prophylaxis (PrEP): Used to... ### Desipramine **Generic:** desipramine Findability: 62/100 | Insurance: $0–$30 | Cash: $20–$116 What Is Desipramine? Desipramine is a tricyclic antidepressant (TCA) available as a generic medication and formerly under the brand name Norpramin. The FDA first approved it in 1964 for the treatment of major depressive disorder in adults. It remains in use today, primarily as a second- or third-line antidepressant when newer medications such as SSRIs or SNRIs have been insufficient. Beyond depression, desipramine is widely used off-label for ADHD, neuropathic pain, bulimia nervosa, irritable... ### Desloratadine **Generic:** desloratadine Findability: 45/100 | Insurance: $5–$30 | Cash: $13–$338 What Is Desloratadine (Clarinex)? Desloratadine is a prescription second-generation antihistamine sold under the brand name Clarinex. It was first approved by the FDA in 2001 and is used to treat seasonal and year-round allergic rhinitis (hay fever) and chronic idiopathic urticaria (chronic hives). It is the active metabolite of Loratadine (Claritin), meaning it is the compound your body naturally converts Loratadine into after you take it. Unlike Loratadine, Cetirizine (Zyrtec), and... ### Desogestrel/Ethinyl Estradiol **Generic:** desogestrel/ethinyl estradiol Findability: 82/100 | Insurance: $0-$30 | Cash: $28-$160 What Is Desogestrel/Ethinyl Estradiol? Desogestrel/ethinyl estradiol is a combination hormonal birth control pill (oral contraceptive) containing two synthetic hormones: desogestrel (a third-generation progestin) and ethinyl estradiol (a synthetic estrogen). It is available under more than 25 brand names in the United States, including Apri, Reclipsen, Kariva, Mircette, Enskyce, Azurette, Viorele, Cyclessa, and many others. The medication is FDA-approved for contraception (prevention of... ### Desoxyn **Generic:** Desoxyn Findability: 30/100 | Shortage: active | Insurance: $50–$150 | Cash: $120–$1,135 What Is Desoxyn? Desoxyn is the brand name for Methamphetamine Hydrochloride, a prescription central nervous system (CNS) stimulant. It is FDA-approved for treating Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6 and older, and as a short-term adjunct for obesity in patients who haven't responded to other treatments. Desoxyn is considered a last-line option for ADHD, typically prescribed only after other stimulants like Adderall, Vyvanse, or Ritalin have been tried and found... ### Desvenlafaxine XR **Generic:** Desvenlafaxine XR Findability: 75/100 | Insurance: $5–$25 | Cash: $15–$150 What Is Desvenlafaxine XR? Desvenlafaxine XR is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant approved by the FDA for the treatment of major depressive disorder (MDD). It is the active metabolite of venlafaxine (Effexor XR). Brand-name versions include Pristiq, Khedezla, Desfax, and Ellefore. Generic versions are widely available and significantly more affordable. In addition to depression, Desvenlafaxine XR is sometimes prescribed off-label for menopausal hot flashes,... ### Dexedrine **Generic:** Dexedrine Findability: 45/100 | Shortage: active | Insurance: $10–$50 | Cash: $20–$685 What Is Dexedrine? Dexedrine (Dextroamphetamine sulfate) is a central nervous system (CNS) stimulant in the amphetamine class. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and Narcolepsy. Dextroamphetamine is the dextro-isomer of amphetamine and is considered more potent per milligram than mixed amphetamine salts (Adderall). It is available as immediate-release tablets, extended-release capsules (Dexedrine Spansule), an oral solution (ProCentra), and... ### Dexedrine XR **Generic:** Dexedrine XR Findability: 35/100 | Shortage: active | Insurance: $10–$50 | Cash: $20–$685 What Is Dexedrine XR? Dexedrine XR (dextroamphetamine sulfate extended-release) is an amphetamine stimulant medication approved for treating ADHD in patients 6 years and older. It's the extended-release version of Dexedrine, providing once-daily dosing through its Spansule capsule technology. The medication is manufactured by Catalent Pharma Solutions for Amneal Pharmaceuticals and is available in both brand and generic formulations. ### Dexmethylphenidate XR **Generic:** Dexmethylphenidate XR Findability: 40/100 | Shortage: active | Insurance: $10–$50 | Cash: $40–$490 What Is Dexmethylphenidate XR? Dexmethylphenidate XR is an extended-release CNS stimulant prescribed for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. It is the purified, pharmacologically active d-threo enantiomer of racemic methylphenidate, which means it contains only the more potent half of the methylphenidate molecule. The brand-name version is sold as Focalin XR, manufactured by Novartis Pharmaceuticals. The extended-release... ### Dexmethylphenidate/Serdexmethylphenidate **Generic:** dexmethylphenidate/serdexmethylphenidate Findability: 55/100 | Insurance: $0–$60 | Cash: $445–$598 What Is Dexmethylphenidate/Serdexmethylphenidate (Azstarys)? Azstarys (serdexmethylphenidate/dexmethylphenidate) is a once-daily prescription central nervous system (CNS) stimulant approved by the FDA on March 2, 2021, for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. It is manufactured by Corium, a Sun Pharmaceutical company. Azstarys is a combination product containing two ingredients in a fixed 70/30 molar ratio: serdexmethylphenidate... ### Dextroamphetamine **Generic:** Dextroamphetamine Findability: 30/100 | Shortage: active | Insurance: $10–$50 | Cash: $30–$400 What Is Dextroamphetamine? Dextroamphetamine is a central nervous system (CNS) stimulant approved by the FDA for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and Narcolepsy. It is the dextro-isomer of amphetamine and is available as a generic medication as well as under brand names including Dexedrine, Zenzedi, and ProCentra. Dextroamphetamine helps improve focus, attention, and impulse control in patients with ADHD, and reduces excessive daytime sleepiness in patients... ### Dextroamphetamine XR **Generic:** Dextroamphetamine XR Findability: 35/100 | Shortage: active | Insurance: $5–$50 | Cash: $32–$250 What Is dextroamphetamine xr? Dextroamphetamine xr (extended-release) is a central nervous system (CNS) stimulant used to treat Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 and older, as well as narcolepsy. Originally sold under the brand name Dexedrine Spansule (now discontinued), dextroamphetamine xr is available as a generic extended-release capsule from manufacturers including Teva, Mallinckrodt, and Alvogen. The extended-release capsule releases medication gradually... ### Dhivy **Generic:** carbidopa/levodopa Findability: 62/100 | Insurance: $0–$60 | Cash: $45–$135 What Is Dhivy? Dhivy (pronounced "divvy") is a brand-name oral tablet containing carbidopa and levodopa, manufactured by Avion Pharmaceuticals (a subsidiary of Alora Pharmaceuticals). It is FDA-approved for the treatment of Parkinson's disease, post-encephalitic parkinsonism, and symptomatic parkinsonism caused by carbon monoxide or manganese intoxication. What makes Dhivy unique is its innovative tablet design: three functional score lines allow the tablet to be snapped cleanly into four... ### Diazepam **Generic:** Diazepam Findability: 65/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $5–$30 What Is Diazepam? Diazepam is a benzodiazepine medication originally marketed under the brand name Valium. It is one of the most widely recognized and prescribed benzodiazepines in the world. Diazepam is FDA-approved for the treatment of anxiety disorders, muscle spasms, seizures (including status epilepticus), preoperative anxiety, and acute alcohol withdrawal symptoms such as agitation, tremor, and delirium tremens. Diazepam is available in multiple formulations including oral tablets, oral... ### Diclegis **Generic:** doxylamine-pyridoxine Findability: 78/100 | Insurance: $0–$30 | Cash: $45–$423 What Is Diclegis? Diclegis is a brand-name prescription medication containing doxylamine succinate 10 mg and pyridoxine hydrochloride (vitamin B6) 10 mg in a delayed-release tablet. It is manufactured by Duchesnay USA and received FDA approval in April 2013 as the only medication specifically indicated for nausea and vomiting of pregnancy (NVP) in the United States. Diclegis carries FDA Pregnancy Category A status — the safest available classification — meaning controlled studies in pregnant... ### Diclofenac **Generic:** diclofenac Findability: 82/100 | Insurance: $0–$30 | Cash: $10–$40 What Is Diclofenac? Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It is one of the most widely prescribed pain medications in the United States, with over 9 million prescriptions dispensed in 2023 alone. It is available in many forms, including oral tablets and capsules, topical gel and patch, oral powder, and intravenous solution. Diclofenac is sold under several brand names including Voltaren, Cataflam, Cambia,... ### Dicloxacillin **Generic:** dicloxacillin Findability: 78/100 | Insurance: $0-$20 | Cash: $22-$115 What Is Dicloxacillin? Dicloxacillin is a prescription antibiotic in the penicillin family, specifically classified as a penicillinase-resistant penicillin (also called an isoxazolyl penicillin). It was patented in 1961 and approved by the FDA for medical use in 1968. The brand name Dynapen has been discontinued; all Dicloxacillin available today is generic (dicloxacillin sodium). Dicloxacillin is indicated for infections caused by penicillinase-producing staphylococci — primarily... ### Dicyclomine **Generic:** dicyclomine Findability: 88/100 | Insurance: $0–$10 | Cash: $3–$22 What Is Dicyclomine? Dicyclomine (also known as dicycloverine) is a prescription anticholinergic antispasmodic medication approved by the FDA in 1950 for the treatment of irritable bowel syndrome (IBS). It is the active ingredient in the brand-name medication Bentyl, though Bentyl's oral tablet, capsule, and liquid forms have been discontinued — only the generic version is available for oral use today. In 2023, dicyclomine was the 192nd most commonly prescribed medication in the United... ### Dificid **Generic:** Dificid Findability: 55/100 | Shortage: monitoring | Insurance: $50–$150 | Cash: $1,290–$6,550 What Is Dificid? Dificid (Fidaxomicin) is a macrocyclic antibiotic approved by the FDA for the treatment of Clostridioides difficile-associated diarrhea (CDAD) in adults and pediatric patients aged 6 months and older. C. difficile infections (often called "C. diff") are a serious and sometimes life-threatening cause of antibiotic-associated diarrhea, particularly in hospitalized and elderly patients. Dificid is considered a first-line treatment for C. diff infections per the 2021 IDSA/SHEA... ### Diflucan **Generic:** fluconazole Findability: 88/100 | Insurance: $0–$30 | Cash: $3–$35 What Is Diflucan (Fluconazole)? Diflucan is the brand name for fluconazole, a prescription antifungal medication in the triazole class. Originally developed by Pfizer and FDA-approved in 1990, fluconazole is now available as a widely accessible generic from numerous manufacturers. It is one of the most commonly prescribed antifungal agents in the world. Fluconazole treats a broad range of fungal infections — from the common vaginal yeast infection (a single 150 mg dose) to life-threatening... ### Difluprednate **Generic:** Difluprednate Findability: 45/100 | Shortage: active | Insurance: $15-$75 copay | Cash: $380-$450 What Is Difluprednate? Difluprednate (brand name Durezol) is a powerful corticosteroid eye drop used to treat inflammation and pain in the eye. It is FDA-approved for two main uses: Post-surgical eye inflammation — reduces swelling and pain after ocular surgery such as cataract removal Endogenous anterior uveitis — treats inflammation of the uveal tract inside the eye It is also sometimes used off-label for posterior uveitis, diabetic macular edema, severe allergic conjunctivitis, and... ### Dilantin **Generic:** phenytoin Findability: 62/100 | Shortage: active | Insurance: $0–$30 | Cash: $14–$210 What Is Dilantin? Dilantin is the brand name for phenytoin sodium, an anticonvulsant (anti-seizure) medication that has been FDA-approved since 1939. It belongs to the hydantoin class of drugs and is one of the most extensively studied antiepileptic medications in clinical use. The generic version is phenytoin; another brand, Phenytek, is also available. Dilantin is FDA-approved for tonic-clonic (grand mal) seizures and complex partial (temporal lobe) seizures in adults and children. It is... ### Diltiazem XR **Generic:** diltiazem Findability: 60/100 | Insurance: $0-$15 | Cash: $10-$60 What Is Diltiazem XR? Diltiazem XR is an extended-release formulation of diltiazem hydrochloride, a non-dihydropyridine calcium channel blocker in the benzothiazepine chemical class. First approved by the FDA in 1982, it is one of the most widely prescribed cardiovascular medications in the world. The "XR" designation indicates extended-release technology that allows once-daily dosing. Brand names include Cardizem CD, Cardizem LA, Cartia XT, Dilacor XR, Dilt-XR, Tiazac, Taztia XT, and Matzim... ### Disulfiram **Generic:** disulfiram Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $32–$157 What Is Disulfiram? Disulfiram is an FDA-approved prescription medication used to support recovery in people with alcohol use disorder (AUD). It was originally marketed as Antabuse — a brand that has since been discontinued — and has been FDA-approved since 1951, making it one of the longest-standing pharmacological treatments for alcoholism in the world. Disulfiram is one of three FDA-approved medications for AUD, alongside naltrexone (approved 1994) and acamprosate (approved 2004). It is... ### Divigel **Generic:** Divigel Findability: 55/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $32–$900 What Is Divigel? Divigel is a prescription topical estradiol gel used to treat moderate to severe hot flashes (vasomotor symptoms) caused by menopause. It belongs to the estrogen hormone replacement therapy class. The gel is applied once daily to the skin of the upper thigh and delivers estradiol — the primary form of estrogen — directly through the skin into the bloodstream. Divigel is manufactured by Vertical Pharmaceuticals, LLC and is also available as generic estradiol gel 0.1%. It may... ### Dolishale 28 Day **Generic:** Levonorgestrel and Ethinyl Estradiol Findability: 5/100 | Shortage: active | Insurance: $0–$10 | Cash: $20–$60 What Is Dolishale 28 Day? Dolishale 28 Day is a combination oral contraceptive (birth control pill) manufactured by Ingenus Pharmaceuticals, LLC. It contains two active hormones — levonorgestrel (0.09 mg) and ethinyl estradiol (0.02 mg) — in every tablet. Unlike many 28-day birth control packs that include placebo pills for the last week, Dolishale 28 Day contains 28 active hormone tablets with no pill-free break, making it a continuous monophasic regimen. How Does Dolishale 28 Day... ### Dolutegravir/Lamivudine **Generic:** dolutegravir/lamivudine Findability: 62/100 | Insurance: $0–$150 | Cash: $2,000–$3,700 What Is Dolutegravir/Lamivudine (Dovato)? Dolutegravir/lamivudine, sold under the brand name Dovato, is a once-daily, single-tablet, complete HIV-1 treatment manufactured by ViiV Healthcare. It was first approved by the FDA on April 8, 2019 — making it the first two-drug, fixed-dose, complete regimen approved for HIV treatment-naive adults in the United States. Each Dovato tablet contains dolutegravir 50 mg (an integrase strand transfer inhibitor, or INSTI) and lamivudine 300 mg (a nucleoside... ### Doptelet **Generic:** avatrombopag Findability: 55/100 | Insurance: $0–$500+ | Cash: $4,219–$12,657 What Is Doptelet? Doptelet is the brand name for avatrombopag, a second-generation, orally administered thrombopoietin receptor agonist (TPO-RA). It was first approved by the FDA on May 21, 2018, for adults with chronic liver disease (CLD) scheduled to undergo a medical or dental procedure. In 2019, the FDA extended approval to adults with chronic immune thrombocytopenia (ITP), and in July 2025 to pediatric patients one year and older with persistent or chronic ITP. Doptelet works by... ### Doral **Generic:** quazepam Findability: 35/100 | Shortage: active | Insurance: $20–$80 | Cash: $655–$900 What Is Doral (Quazepam)? Doral is the brand name for quazepam, a long-acting benzodiazepine hypnotic approved by the FDA on December 27, 1985 for the treatment of insomnia. It is a member of the 1,4-benzodiazepine drug class and works by enhancing the effects of GABA, the brain's primary inhibitory neurotransmitter, to promote sleep onset and maintenance. Quazepam is FDA-approved for insomnia characterized by difficulty falling asleep, frequent nocturnal awakenings, and early morning... ### Doryx **Generic:** doxycycline hyclate Findability: 45/100 | Insurance: $0–$100 | Cash: $25–$1,657 What Is Doryx? Doryx MPC (doxycycline hyclate delayed-release tablets) is a brand-name prescription antibiotic manufactured by Mayne Pharma. It belongs to the tetracycline class of antibiotics and contains doxycycline hyclate as its active ingredient — a semisynthetic antibiotic derived from oxytetracycline that has been used in medicine since its initial U.S. approval in 1967. The "MPC" in Doryx MPC stands for modified polymer coating — a proprietary delayed-release formulation that protects... ### Dorzolamide **Generic:** dorzolamide Findability: 82/100 | Insurance: $0–$45 | Cash: $15–$80 What Is Dorzolamide? Dorzolamide is a prescription ophthalmic solution used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It belongs to the carbonic anhydrase inhibitor (CAI) drug class and was originally sold under the brand name Trusopt, developed by Merck. The brand-name Trusopt has been discontinued in the U.S. market; dorzolamide is now available as a generic medication only. Approved by the FDA in December 1994, dorzolamide was... ### Doxazosin **Generic:** doxazosin Findability: 88/100 | Insurance: $0–$20 | Cash: $10–$90 What Is Doxazosin? Doxazosin (brand names Cardura and Cardura XL) is a prescription medication belonging to a class of drugs called alpha-1 adrenergic blockers. It was first approved by the FDA in 1990 and has since become one of the most widely prescribed medications for benign prostatic hyperplasia (BPH) and hypertension. Generic versions are manufactured by multiple companies including Teva, Mylan, and Apotex. Doxazosin is available in immediate-release tablets (1 mg, 2 mg, 4 mg, 8 mg)... ### Doxepin **Generic:** doxepin Findability: 75/100 | Insurance: $0–$30 | Cash: $7–$96 What Is Doxepin? Doxepin is a tricyclic antidepressant (TCA) that has been FDA-approved since 1969. It is one of the few medications with FDA approval for multiple distinct conditions: major depressive disorder (MDD), anxiety disorders, and insomnia characterized by sleep maintenance difficulties. It is also available as a topical cream (Zonalon, Prudoxin) for itchy skin conditions including atopic dermatitis and lichen simplex chronicus. Oral doxepin is available as generic capsules (10–150... ### Drizalma Sprinkle **Generic:** duloxetine Findability: 55/100 | Shortage: resolved | Insurance: $30–$75 | Cash: $226–$273 What Is Drizalma Sprinkle? Drizalma Sprinkle is the brand name for duloxetine delayed-release sprinkle capsules, manufactured by Sun Pharmaceutical Industries. It belongs to the SNRI (serotonin-norepinephrine reuptake inhibitor) drug class and is used to treat major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain. What makes Drizalma Sprinkle unique is its formulation: the delayed-release capsule can be opened... ### Dronabinol **Generic:** Dronabinol Findability: 35/100 | Shortage: active | Insurance: $10–$50 | Cash: $68–$900 What Is Dronabinol? Dronabinol is a synthetic form of delta-9-tetrahydrocannabinol (THC), the main psychoactive compound found in cannabis. It is FDA-approved for two conditions: HIV/AIDS-related anorexia with weight loss and chemotherapy-induced nausea and vomiting (CINV) in patients who haven't responded to conventional antiemetics. Dronabinol is sold under the brand name Marinol and is also available as a generic. It works by stimulating appetite and reducing nausea, helping patients... ### Drospirenone/Ethinyl Estradiol **Generic:** drospirenone/ethinyl estradiol Findability: 85/100 | Insurance: $0–$30 | Cash: $15–$230 What Is Drospirenone/Ethinyl Estradiol? Drospirenone/ethinyl estradiol is a combination oral contraceptive containing two synthetic hormones: drospirenone (a fourth-generation progestin) and ethinyl estradiol (a synthetic estrogen). It is available under brand names including Yaz, Yasmin, and over a dozen FDA-approved generic versions including Loryna, Ocella, Syeda, Nikki, Gianvi, Vestura, and Zarah. It comes in two formulations: 3 mg/0.02 mg EE (24-day active regimen, e.g., Yaz and... ### Droxidopa **Generic:** Droxidopa Findability: 30/100 | Shortage: active | Insurance: $30–$200+ | Cash: $37–$2,721 What Is Droxidopa? Droxidopa (brand name Northera) is an FDA-approved medication for neurogenic orthostatic hypotension (nOH) — a condition where blood pressure drops significantly when standing, causing dizziness, lightheadedness, or fainting. It is associated with Parkinson's disease, multiple system atrophy, and pure autonomic failure. Droxidopa was approved by the FDA in February 2014 and is manufactured by Lundbeck. ### Drysol **Generic:** aluminum chloride hexahydrate Findability: 82/100 | Insurance: $5–$30 | Cash: $15–$37 What Is Drysol? Drysol is a prescription-strength topical antiperspirant containing 20% aluminum chloride hexahydrate in anhydrous ethyl alcohol. It is the first-line prescription treatment for primary hyperhidrosis — a medical condition characterized by excessive sweating that goes beyond what the body needs for temperature regulation. Drysol is manufactured by Person & Covey and is available in standard solution and Dab-O-Matic applicator formats. Related brand names include Hypercare (20%)... ### Dulcolax **Generic:** bisacodyl Findability: 82/100 | Insurance: $0–$5 | Cash: $2–$20 What Is Dulcolax? Dulcolax is the brand name for bisacodyl, a stimulant laxative that has been used clinically since the 1950s. It belongs to the diphenylmethane chemical family and is available over the counter without a prescription in the United States. Most people recognize bisacodyl by its most well-known brand name, Dulcolax, though it is also sold as Correctol, Fleet Bisacodyl, Bisac-Evac, Ex-Lax Ultra, and numerous store-brand generics at pharmacies nationwide. Dulcolax is primarily... ### Dulera **Generic:** Dulera Findability: 55/100 | Shortage: monitoring | Insurance: $15 - $75 | Cash: $400 - $500 Dulera is a combination inhaler used for the long-term maintenance treatment of asthma in patients 5 years of age and older. It contains two active ingredients: mometasone furoate, an inhaled corticosteroid (ICS), and formoterol fumarate, a long-acting beta2-agonist (LABA). Dulera is prescribed when asthma is not adequately controlled with an inhaled corticosteroid alone. It is not a rescue inhaler and should not be used to treat sudden breathing problems. Patients still need a separate... ### Dupixent **Generic:** dupilumab Findability: 62/100 | Insurance: $0–$100 | Cash: $4,193–$5,500 What Is Dupixent? Dupixent (dupilumab) is a prescription biologic medication jointly developed and marketed by Sanofi and Regeneron Pharmaceuticals. It was first approved by the FDA on March 28, 2017, for moderate-to-severe atopic dermatitis (eczema) and has since become one of the most broadly approved biologics in medicine, with nine distinct FDA-approved indications as of 2026. Dupixent is approved to treat: atopic dermatitis (ages 6 months+), asthma (ages 6+), chronic rhinosinusitis with... ### Durezol **Generic:** difluprednate Findability: 45/100 | Shortage: active | Insurance: $10–$100 | Cash: $44–$400 What Is Durezol? Durezol is the brand name for difluprednate ophthalmic emulsion 0.05%, a prescription corticosteroid eye drop approved by the FDA in 2008. It is indicated for two conditions: treating inflammation and pain associated with ocular surgery (particularly cataract surgery), and treating endogenous anterior uveitis — inflammation in the front part of the eye caused by the immune system. Durezol belongs to the ophthalmic steroid drug class. It is formulated as an emulsion — a... ### Dutasteride **Generic:** dutasteride Findability: 88/100 | Insurance: $0–$30 | Cash: $4–$170 What Is Dutasteride? Dutasteride is a prescription medication sold under the brand name Avodart (manufactured by GSK). It belongs to a class of drugs called 5-alpha reductase inhibitors (5-ARIs) and is FDA-approved for the treatment of benign prostatic hyperplasia (BPH) — commonly called an enlarged prostate — in men. It is also widely used off-label for androgenetic alopecia (male and female pattern hair loss). Dutasteride was first approved by the FDA in November 2001. Its patent expired in... ### Dutasteride/Tamsulosin **Generic:** dutasteride/tamsulosin Findability: 72/100 | Insurance: $15–$80 | Cash: $99–$451 What Is Dutasteride/Tamsulosin? Dutasteride/tamsulosin, sold under the brand name Jalyn, is an FDA-approved combination capsule for treating benign prostatic hyperplasia (BPH) — the medical term for an enlarged prostate. It was approved by the FDA on June 14, 2010, and is manufactured by GlaxoSmithKline (GSK). The medication brings together two proven BPH treatments in a single once-daily capsule: dutasteride 0.5 mg and tamsulosin hydrochloride 0.4 mg. BPH is an extremely common condition in... ### Dyanavel XR **Generic:** Dyanavel XR Findability: 45/100 | Shortage: active | Insurance: $25–$75 | Cash: $460–$590 What Is Dyanavel XR? Dyanavel XR is a brand-name, extended-release amphetamine medication manufactured by Tris Pharma. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. Dyanavel XR is unique among ADHD stimulants because it is available as both an extended-release oral suspension (liquid) and extended-release tablets, making it a useful option for patients who have difficulty swallowing pills. It is a Schedule II... ### Ebglyss **Generic:** Ebglyss Findability: 35/100 | Shortage: active | Insurance: $0–$50 | Cash: $2,500–$3,800 What Is Ebglyss? Ebglyss (Lebrikizumab-lbkz) is a biologic medication made by Eli Lilly for the treatment of moderate-to-severe atopic dermatitis (eczema) in adults and adolescents aged 12 and older who weigh at least 40 kg (88 lb). It is approved for patients who are candidates for systemic therapy — meaning topical treatments alone haven't been enough to control their symptoms. Ebglyss is administered as a subcutaneous injection that patients can self-administer at home after proper training. ### Edluar **Generic:** zolpidem tartrate Findability: 35/100 | Shortage: active | Insurance: $50–$150 | Cash: $200–$400+ What Is Edluar? Edluar is a brand-name prescription sleep medication containing zolpidem tartrate — the same active ingredient found in Ambien. What makes Edluar unique is its sublingual tablet form: you place it under your tongue and let it dissolve, rather than swallowing it. This sublingual delivery allows the medication to be absorbed directly through oral mucous membranes for fast onset. Edluar was originally marketed as Sublinox before receiving FDA approval on March 13, 2009. It is... ### Effient **Generic:** Effient Findability: 75/100 | Insurance: $5–$30 | Cash: $19–$733 What Is Effient? Effient (Prasugrel) is a prescription antiplatelet medication used to reduce the risk of blood clots in patients with acute coronary syndromes (ACS) who have undergone percutaneous coronary intervention (PCI), such as stent placement. It is always taken in combination with aspirin. Effient belongs to the thienopyridine class of P2Y12 platelet inhibitors and is manufactured by Daiichi Sankyo and Eli Lilly. It was FDA-approved to help prevent heart attacks, strokes, and stent... ### Elahere **Generic:** mirvetuximab soravtansine-gynx Findability: 55/100 | Insurance: $0–$5,000+/cycle | Cash: $6,715+/vial What Is Elahere? Elahere (mirvetuximab soravtansine-gynx) is a first-in-class antibody-drug conjugate (ADC) manufactured by AbbVie. The FDA granted accelerated approval on November 14, 2022, and full approval on March 22, 2024. It is indicated for adult patients with folate receptor alpha (FRα) positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer who have received one to three prior systemic treatment regimens. Elahere is the first ADC approved for... ### Eletriptan **Generic:** eletriptan Findability: 82/100 | Insurance: $0–$50 | Cash: $21–$420 What Is Eletriptan? Eletriptan, sold under the brand name Relpax and manufactured by Pfizer, is a second-generation triptan medication used for the acute treatment of migraine headaches with or without aura in adults. It was FDA-approved in December 2002. Generic eletriptan has been available since 2017, making it significantly more affordable than the brand. Eletriptan is taken at the first sign of a migraine to stop the attack in progress. It is not intended to prevent migraines or reduce... ### Eliquis **Generic:** Eliquis Findability: 65/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $520–$800 What Is Eliquis? Eliquis (Apixaban) is a prescription blood thinner classified as a direct oral anticoagulant (DOAC) and Factor Xa inhibitor. It is manufactured by the Bristol-Myers Squibb and Pfizer Alliance. Eliquis is FDA-approved to: Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AFib) Treat deep vein thrombosis (DVT) and pulmonary embolism (PE) Reduce the risk of recurrent DVT and PE after initial therapy Prevent DVT following hip or... ### Ella **Generic:** Ella Findability: 58/100 | Shortage: monitoring | Insurance: $0–$30 | Cash: $39–$90 What Is Ella? Ella (Ulipristal Acetate) is a prescription emergency contraceptive used to prevent pregnancy after unprotected intercourse or contraceptive failure. It is effective when taken up to 120 hours (5 days) after unprotected sex, making it the longest-acting oral emergency contraceptive available. Ella was approved by the FDA and is manufactured by Laboratoire HRA Pharma, now owned by Perrigo Company plc. Unlike over-the-counter options like Plan B, Ella requires a prescription,... ### Emend **Generic:** aprepitant Findability: 72/100 | Shortage: resolved | Insurance: $40–$60 | Cash: $32–$170 What Is Emend (Aprepitant)? Emend (aprepitant) is a prescription antiemetic medication used to prevent nausea and vomiting associated with chemotherapy and surgery. It was the first neurokinin-1 (NK1) receptor antagonist approved by the FDA, receiving initial approval in 2003. It is manufactured by Merck Sharp & Dohme and is also widely available as generic aprepitant from multiple manufacturers. Emend is FDA-approved for prevention of acute and delayed nausea and vomiting associated with... ### Emgality **Generic:** Emgality Findability: 45/100 | Shortage: active | Insurance: $0–$150 | Cash: $700–$950 What Is Emgality? Emgality (Galcanezumab-gnlm) is a prescription biologic medication manufactured by Eli Lilly and Company. It belongs to the CGRP (calcitonin gene-related peptide) antagonist class and is a humanized monoclonal antibody. Emgality is FDA-approved for two indications: Preventive treatment of migraine in adults (approved September 2018) Treatment of episodic cluster headache in adults (approved June 2019) — it is the first and only FDA-approved treatment specifically for... ### Emsam **Generic:** selegiline transdermal system Findability: 62/100 | Insurance: $20–$77 | Cash: $2,274–$2,799 What Is Emsam? Emsam is the brand name for the selegiline transdermal system — a once-daily skin patch used to treat major depressive disorder (MDD) in adults and adolescents aged 12 and older. It was FDA-approved on February 27, 2006, and holds a unique distinction: it is the only transdermal antidepressant patch approved in the United States, and the only antidepressant that is not taken orally. Emsam belongs to the monoamine oxidase inhibitor (MAOI) drug class. It is manufactured by... ### Enalapril **Generic:** enalapril Findability: 82/100 | Insurance: $0–$10 | Cash: $17–$50 What Is Enalapril? Enalapril (brand names Vasotec and Epaned) is a prescription angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension), symptomatic congestive heart failure, and asymptomatic left ventricular dysfunction. It is one of the most widely prescribed cardiovascular medications in the world, included on the WHO List of Essential Medicines, and ranked among the top 200 most prescribed drugs in the United States. Originally developed by Merck and... ### Endometrin **Generic:** Endometrin Findability: 40/100 | Shortage: active | Insurance: $30–$75 | Cash: $91–$393 What Is Endometrin? Endometrin is a brand-name prescription medication containing micronized progesterone in a vaginal insert form. It is FDA-approved for progesterone supplementation as part of Assisted Reproductive Technology (ART) treatment for infertile women. This includes IVF (in vitro fertilization) cycles where the body may not produce enough progesterone on its own to support embryo implantation and early pregnancy. Endometrin is manufactured by Ferring Pharmaceuticals and comes in a... ### Enpresse 28 Day **Generic:** Enpresse 28 Day Findability: 65/100 | Shortage: monitoring | Insurance: $0–$0 | Cash: $11–$75 What Is Enpresse 28 Day? Enpresse 28 Day is a triphasic combination oral contraceptive containing levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). It is FDA-approved for the prevention of pregnancy. The triphasic design means the hormone levels change across three phases during each 28-day cycle, more closely mimicking the body's natural hormonal fluctuations. In addition to contraception, Enpresse 28 Day is sometimes prescribed off-label for regulating menstrual cycles,... ### Entecavir **Generic:** entecavir Findability: 80/100 | Insurance: $10–$60 | Cash: $11–$31 What Is Entecavir? Entecavir (brand name Baraclude) is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection in adults and children aged 2 years and older who weigh at least 10 kilograms (22 pounds). It belongs to the nucleoside reverse transcriptase inhibitor (NRTI) drug class—specifically, it is a deoxyguanosine analogue that blocks HBV replication. Entecavir was FDA-approved in March 2005. Bristol-Myers Squibb originally marketed it as Baraclude, but the patent... ### Entrectinib **Generic:** entrectinib Findability: 65/100 | Insurance: $0–$500 | Cash: $7,500–$8,500 What Is Entrectinib? Entrectinib is an oral targeted cancer therapy sold under the brand name Rozlytrek, manufactured by Genentech (a Roche Group member). It was FDA-approved in August 2019 and belongs to the class of multikinase inhibitors. It is indicated for adults with ROS1-positive metastatic non-small cell lung cancer (NSCLC) and for adults and pediatric patients older than 1 month with NTRK gene fusion-positive solid tumors. Entrectinib is a "tumor-agnostic" therapy for NTRK fusion... ### Envarsus XR **Generic:** Envarsus XR Findability: 60/100 | Shortage: monitoring | Insurance: $25–$100 | Cash: $270–$1,500 What Is Envarsus XR? Envarsus XR is a once-daily, extended-release formulation of Tacrolimus, a calcineurin inhibitor immunosuppressant. It is FDA-approved for the prevention of organ rejection in kidney transplant patients — both in new (de novo) transplant recipients and in patients converting from twice-daily immediate-release Tacrolimus (Prograf). Envarsus XR uses a proprietary MeltDose technology that improves Tacrolimus bioavailability, allowing for once-daily dosing with more consistent... ### Eohilia **Generic:** Eohilia Findability: 40/100 | Shortage: active | Insurance: $0–$2,524 | Cash: $1,927–$2,524 What Is Eohilia? Eohilia (budesonide oral suspension) is a prescription corticosteroid medication FDA-approved in February 2024 for the treatment of eosinophilic esophagitis (EoE) in patients 11 years of age and older. EoE is a chronic immune-mediated condition where eosinophils (a type of white blood cell) build up in the esophagus, causing inflammation, difficulty swallowing, and food impaction. Eohilia is specifically formulated as a swallowed oral suspension designed to coat the esophagus... ### Epaned **Generic:** enalapril maleate Findability: 62/100 | Insurance: $0–$60 | Cash: $68–$419 What Is Epaned? Epaned is the brand name for enalapril maleate oral solution, 1 mg/mL — the first and only FDA-approved enalapril liquid formulation. First approved on August 13, 2013, and manufactured by Azurity Pharmaceuticals, it was developed specifically for patients who cannot swallow tablets: infants and young children with hypertension, and adults with dysphagia or swallowing difficulties. Epaned is an ACE inhibitor (angiotensin-converting enzyme inhibitor), a well-established class... ### Epclusa **Generic:** sofosbuvir/velpatasvir Findability: 72/100 | Insurance: $0–$250 | Cash: $6,728–$24,350 What Is Epclusa? Epclusa (sofosbuvir 400 mg/velpatasvir 100 mg) is a once-daily oral prescription medication used to treat chronic hepatitis C virus (HCV) infection. It was FDA-approved on June 28, 2016 and was the first single-tablet regimen approved for all six hepatitis C genotypes (1 through 6). Epclusa is manufactured by Gilead Sciences, with an authorized generic available through Asegua Therapeutics (a Gilead affiliate). Epclusa is indicated for adults and children 3 years and older... ### Epidiolex **Generic:** cannabidiol Findability: 45/100 | Insurance: $0–$300 | Cash: $1,050–$1,500 What Is Epidiolex? Epidiolex is the first and only FDA-approved prescription cannabidiol (CBD) medication in the United States. Approved on June 25, 2018, it is manufactured by Jazz Pharmaceuticals (formerly GW Pharmaceuticals). Epidiolex is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome, and tuberous sclerosis complex (TSC) in patients 1 year of age and older. Epidiolex is formulated as a 100 mg/mL oral solution with a strawberry... ### Epinephrine **Generic:** epinephrine Findability: 48/100 | Shortage: active | Insurance: $0–$60 | Cash: $150–$650 What Is Epinephrine? Epinephrine — also known as adrenaline — is a naturally occurring hormone and neurotransmitter that acts as both a sympathomimetic and a catecholamine. As a prescription medication, it is the drug of choice for emergency treatment of anaphylaxis, the severe and potentially fatal allergic reaction that can be triggered by foods, insect stings, medications, and other allergens. Epinephrine is available in multiple forms. Auto-injectors — including EpiPen, EpiPen Jr, Auvi-Q,... ### Eplerenone **Generic:** eplerenone Findability: 85/100 | Insurance: $0–$45 | Cash: $17–$145 What Is Eplerenone? Eplerenone (brand name Inspra) is a prescription medication belonging to the mineralocorticoid receptor antagonist (MRA) class. It works by blocking aldosterone, a hormone that causes the kidneys to retain sodium and water — which raises blood pressure and stresses the heart. By blocking aldosterone's action, Eplerenone lowers blood pressure, reduces fluid retention, and protects the heart from aldosterone-driven damage. Eplerenone has two FDA-approved indications:... ### Eprontia **Generic:** Eprontia Findability: 55/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $85–$334 What Is Eprontia? Eprontia is a brand-name oral liquid solution of Topiramate, manufactured by Azurity Pharmaceuticals. It is an anticonvulsant (antiepileptic) medication approved by the FDA for: Initial monotherapy or adjunctive therapy for partial-onset or primary generalized tonic-clonic seizures in patients 2 years and older Adjunctive therapy for seizures associated with Lennox-Gastaut syndrome in patients 2 years and older Preventive treatment of migraine headaches in patients 12... ### Ergomar **Generic:** ergotamine tartrate Findability: 55/100 | Insurance: $0–$80 | Cash: $322–$2,092 What Is Ergomar? Ergomar is the brand name for ergotamine tartrate 2 mg sublingual tablets, manufactured by Pangea Pharmaceuticals. It is the only sublingual ergotamine product currently available in the United States. Unlike older ergotamine-caffeine combination tablets, Ergomar is caffeine-free and aspartame-free. Ergomar belongs to a class of drugs called ergot alkaloids—naturally occurring compounds derived from the ergot fungus. It is FDA-approved as an abortive treatment for migraine... ### Ertaczo **Generic:** Ertaczo Findability: 45/100 | Shortage: active | Insurance: $30–$75 | Cash: $447–$1,070 What Is Ertaczo? Ertaczo (Sertaconazole Nitrate) is a prescription topical antifungal cream used to treat interdigital tinea pedis (athlete's foot) in adults and children 12 years and older. It belongs to the imidazole class of azole antifungals and is applied directly to the affected skin between the toes and surrounding area. Ertaczo is FDA-approved for athlete's foot caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. It may also be prescribed off-label... ### Erythromycin Ethylsuccinate **Generic:** erythromycin ethylsuccinate Findability: 72/100 | Insurance: $0–$20 | Cash: $15–$80 What Is Erythromycin Ethylsuccinate? Erythromycin Ethylsuccinate (brand names E.E.S. and EryPed) is an oral macrolide antibiotic used to treat a wide range of bacterial infections. It is an ester form of erythromycin, chemically modified to improve oral absorption and stability. It has been in clinical use since the 1950s and remains an important option for patients who are allergic to penicillin. Erythromycin Ethylsuccinate is FDA-approved for upper and lower respiratory tract infections,... ### Escitalopram **Generic:** escitalopram Findability: 90/100 | Insurance: $0–$20 | Cash: $8–$57 What Is Escitalopram? Escitalopram is a selective serotonin reuptake inhibitor (SSRI) antidepressant sold under the brand name Lexapro. It was developed by Lundbeck and Forest Laboratories and received FDA approval for Major Depressive Disorder in August 2002 and for Generalized Anxiety Disorder in December 2003. It is the purified S-enantiomer of citalopram (Celexa), making it more potent and selective than its predecessor. Generic escitalopram has been available since 2006 and is now... ### Esgic **Generic:** butalbital/acetaminophen/caffeine Findability: 60/100 | Shortage: active | Insurance: $0–$20 | Cash: $15–$55 What Is Esgic? Esgic is a prescription combination medication used to treat tension (muscle contraction) headaches. It contains three active ingredients: butalbital (50mg), acetaminophen (325mg), and caffeine (40mg). The FDA approved this combination in November 1984. Both brand-name Esgic and the related brand Fioricet have been discontinued; the medication is now available exclusively as generic butalbital/acetaminophen/caffeine from various manufacturers. Esgic is indicated for the acute... ### Esomeprazole/Naproxen **Generic:** esomeprazole/naproxen Findability: 62/100 | Insurance: $10–$60 | Cash: $120–$350 What Is Esomeprazole/Naproxen? Esomeprazole/naproxen, previously sold under the brand name Vimovo, is an FDA-approved prescription combination medication containing two active ingredients: naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that reduces arthritis pain and inflammation, and esomeprazole, a proton pump inhibitor (PPI) that reduces stomach acid and protects the stomach lining from ulcers caused by naproxen therapy. First approved by the FDA in 2010, esomeprazole/naproxen is... ### Estazolam **Generic:** Estazolam Findability: 55/100 | Shortage: monitoring | Insurance: $10–$40 | Cash: $25–$160 What Is Estazolam? Estazolam is a benzodiazepine medication FDA-approved for the short-term treatment of insomnia. It helps people who have difficulty falling asleep or staying asleep. Originally marketed under the brand name ProSom by Abbott Laboratories, the brand has since been discontinued and Estazolam is now available only as a generic. It is typically prescribed for 7–10 days and is taken at bedtime. Patients should plan for a full 7–8 hours of sleep after taking it to avoid next-day... ### Estradiol Transdermal **Generic:** Estradiol Transdermal Findability: 42/100 | Shortage: active | Insurance: $5–$30 | Cash: $26–$110 What Is Estradiol Transdermal? Estradiol transdermal is a prescription hormone replacement therapy (HRT) delivered through a skin patch. It contains estradiol, the primary and most potent natural estrogen produced by the ovaries. The patch delivers a steady, controlled dose of estradiol through the skin and directly into the bloodstream. Estradiol transdermal patches are FDA-approved for: Moderate-to-severe vasomotor symptoms (hot flashes, night sweats) associated with... ### Estradiol/Norethindrone **Generic:** Estradiol/Norethindrone Findability: 55/100 | Shortage: monitoring | Insurance: $10–$45 | Cash: $15–$200 What Is Estradiol/Norethindrone? Estradiol/Norethindrone is a combination hormone replacement therapy (HRT) containing an estrogen (estradiol) and a progestin (norethindrone acetate). It is FDA-approved for the treatment of moderate-to-severe vasomotor symptoms (hot flashes) associated with menopause, moderate-to-severe vulvar and vaginal atrophy, and the prevention of postmenopausal osteoporosis. It is available as oral tablets under brand names such as Activella, Amabelz, Lopreeza, and... ### Estradiol/Norgestimate **Generic:** estradiol/norgestimate Findability: 65/100 | Insurance: $30–$80 | Cash: $190–$230 What Is Estradiol/Norgestimate? Estradiol/Norgestimate is a combination hormone replacement therapy (HRT) medication sold under the brand name Prefest, manufactured by Teva Pharmaceuticals. It contains two components: estradiol (1 mg), a bioidentical estrogen, and norgestimate (0.09 mg), a third-generation progestin. It is available only as a brand-name product — no generic equivalent exists as of 2026. Prefest is FDA-approved for postmenopausal women who have an intact uterus for three... ### Estratest **Generic:** esterified estrogens/methyltestosterone Findability: 42/100 | Shortage: active | Insurance: $10–$50 | Cash: $30–$150 What Is Estratest? Estratest is a combination hormone therapy that pairs esterified estrogens with methyltestosterone — a synthetic testosterone — in a single oral tablet. The original Estratest brand was manufactured by Solvay Pharmaceuticals and marketed in the United States starting in 1964. Solvay discontinued the brand in March 2009, but the medication remains available as a generic under names including EEMT, EEMT HS, and Covaryx. It is prescribed for postmenopausal women experiencing... ### Estring **Generic:** estradiol vaginal system Findability: 55/100 | Shortage: resolved | Insurance: $25–$60 | Cash: $249–$670 What Is Estring? Estring is a brand-name prescription medication manufactured by Pfizer (Pharmacia & Upjohn Company LLC). It is a soft, flexible vaginal ring containing 2 mg of estradiol — the primary form of estrogen produced by the ovaries. When inserted into the upper vaginal vault, Estring releases approximately 7.5 mcg of estradiol per 24 hours in a consistent, stable manner over 90 days. Estring is FDA-approved for the treatment of moderate to severe vulvar and vaginal atrophy (VVA) and... ### Estrogens, Esterified **Generic:** Estrogens, Esterified Findability: 58/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $80–$200 What Is Estrogens, Esterified? Estrogens, Esterified is a synthetic estrogen medication used primarily for hormone replacement therapy (HRT) in menopausal and postmenopausal women. It contains a mixture of esterified estrogens — synthetic compounds that mimic the effects of naturally produced estrogen in the body. It is FDA-approved for treating moderate to severe hot flashes and vaginal atrophy associated with menopause, as well as female hypogonadism, primary ovarian failure, prevention of... ### Eszopiclone **Generic:** Eszopiclone Findability: 70/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $17–$340 What Is Eszopiclone? Eszopiclone is a prescription sleep medication (sedative-hypnotic) used to treat insomnia. It is the active S-isomer of Zopiclone and is sold under the brand name Lunesta. Eszopiclone is FDA-approved for both sleep-onset and sleep-maintenance insomnia, meaning it can help you fall asleep faster and stay asleep longer. Unlike some other sleep aids, Eszopiclone is approved for longer-term use and does not carry the same short-term-only restrictions. It is taken as a tablet... ### Etanercept **Generic:** etanercept Findability: 72/100 | Insurance: $0–$2,000/yr | Cash: $8,000–$11,000/mo What Is Etanercept? Etanercept (brand name Enbrel) is a prescription biologic medication used to treat several serious autoimmune conditions. It is a TNF (tumor necrosis factor) inhibitor — specifically a fusion protein — that works by binding and neutralizing TNF-alpha and TNF-beta, proteins that drive chronic inflammation in autoimmune disease. Etanercept is FDA-approved for moderately to severely active rheumatoid arthritis (RA), polyarticular juvenile idiopathic arthritis (JIA) in... ### Ethinyl Estradiol/Levonorgestrel **Generic:** ethinyl estradiol/levonorgestrel Findability: 88/100 | Insurance: $0–$10 | Cash: $23–$90 What Is Ethinyl Estradiol/Levonorgestrel? Ethinyl estradiol/levonorgestrel is a combination hormonal oral contraceptive — one of the most prescribed medications in the United States. It contains two synthetic hormones: ethinyl estradiol (a synthetic estrogen) and levonorgestrel (a synthetic progestin). Together, these hormones work primarily by suppressing ovulation to prevent pregnancy. Available in more than 30 branded and generic formulations, this medication is sold under names including... ### Ethosuximide **Generic:** Ethosuximide Findability: 55/100 | Shortage: monitoring | Insurance: $5–$30 | Cash: $32–$580 What Is Ethosuximide? Ethosuximide is a succinimide anticonvulsant medication FDA-approved for the treatment of absence seizures (petit mal) in patients aged 3 and older. It is considered a first-line treatment for absence seizures and has been used for decades. Ethosuximide is available as both a generic and under the brand name Zarontin, manufactured by Pfizer. It is taken orally as a capsule or liquid solution, typically once or twice daily. ### Ethyl Chloride **Generic:** Ethyl Chloride Findability: 55/100 | Shortage: monitoring | Insurance: $0–$25 | Cash: $30–$65 What Is Ethyl Chloride? Ethyl Chloride (Chloroethane) is a vapocoolant skin refrigerant and topical anesthetic classified as an FDA-cleared prescription medical device. It is manufactured exclusively by Gebauer Company in Cleveland, Ohio, and sold under the brand name Gebauer's Ethyl Chloride. Ethyl Chloride is used to provide temporary pain control for: Injections, IV starts, and venipuncture Minor surgical procedures such as lancing boils and incision and drainage of small... ### Evamist **Generic:** estradiol Findability: 60/100 | Insurance: $25–$60 | Cash: $75–$181 What Is Evamist? Evamist is a brand-name prescription hormone therapy spray containing estradiol — a naturally occurring form of estrogen. It is the only FDA-approved estrogen therapy delivered as a transdermal spray, manufactured by Padagis and relaunched in 2022. Each spray delivers a precisely measured dose of 1.53 mg of 17β-estradiol. Evamist is applied once daily to the inner surface of the forearm, where estradiol is absorbed through the skin directly into the bloodstream — bypassing... ### Evenity **Generic:** romosozumab Findability: 65/100 | Insurance: $0–$500 | Cash: $2,600–$3,400 What Is Evenity? Evenity (romosozumab-aqqg) is a humanized monoclonal antibody — a biologic medication — approved by the U.S. FDA in April 2019. It is manufactured by Amgen in collaboration with UCB Pharma. Evenity is classified as a sclerostin inhibitor, representing a first-of-its-kind mechanism in osteoporosis treatment. Evenity is indicated for the treatment of osteoporosis in postmenopausal women at high risk for fracture — defined as a history of osteoporotic fracture, multiple risk... ### Excedrin **Generic:** acetaminophen / aspirin / caffeine Findability: 88/100 | Shortage: resolved | Insurance: $0 | Cash: $8–$25 What Is Excedrin? Excedrin is an over-the-counter combination analgesic (pain reliever) containing three active ingredients: acetaminophen (250 mg), aspirin (250 mg), and caffeine (65 mg) per tablet. It is manufactured by Haleon (formerly GlaxoSmithKline) and is available without a prescription at pharmacies, grocery stores, and mass retailers nationwide. Excedrin is used for the temporary relief of migraine headaches, tension headaches, sinus headaches, muscle aches, toothaches, menstrual... ### Exemestane **Generic:** exemestane Findability: 72/100 | Insurance: $0–$30 | Cash: $29–$530 What Is Exemestane? Exemestane (brand name Aromasin, manufactured by Pfizer/Pharmacia & Upjohn) is a prescription medication used to treat hormone receptor-positive (ER-positive) breast cancer in postmenopausal women. It belongs to a class of drugs called aromatase inhibitors and was first approved by the FDA in 1999. Generic exemestane has been available since approximately 2018 from manufacturers including Alvogen, Breckenridge, Cipla, and Mylan. The FDA has approved exemestane for two main... ### Exparel **Generic:** bupivacaine liposome injectable suspension Findability: 78/100 | Insurance: $0–$200 | Cash: $285–$997 What Is Exparel? Exparel (bupivacaine liposome injectable suspension) is a long-acting, non-opioid local anesthetic manufactured by Pacira BioSciences, Inc. It uses the company's proprietary DepoFoam drug delivery technology to encapsulate bupivacaine inside multivesicular liposomes — tiny honeycomb-structured fat particles that slowly release the drug over time. A single injection provides postoperative pain relief for up to 72 hours. Unlike standard bupivacaine, which wears off in 4–8... ### Eyemycin **Generic:** erythromycin ophthalmic Findability: 42/100 | Shortage: active | Insurance: $0–$20 | Cash: $15–$42 What Is Eyemycin? Eyemycin is a brand name for erythromycin ophthalmic ointment 0.5% — a prescription antibiotic applied directly to the eye. While the Eyemycin brand name has been discontinued in the United States, generic erythromycin ophthalmic ointment (manufactured by Bausch & Lomb) remains available and is clinically equivalent. Erythromycin belongs to the macrolide class of antibiotics. As a sterile ophthalmic ointment (5 mg/g in a base of mineral oil and white petrolatum), it is... ### Eysuvis **Generic:** loteprednol etabonate ophthalmic suspension Findability: 55/100 | Insurance: $30–$150 | Cash: $479–$687 What Is Eysuvis? Eysuvis (loteprednol etabonate ophthalmic suspension 0.25%) is a prescription corticosteroid eye drop manufactured by Alcon Laboratories. It was FDA-approved in October 2020 and became commercially available in January 2021 as the first and only FDA-approved prescription corticosteroid specifically indicated for the short-term treatment of dry eye disease. Eysuvis is approved for adults with dry eye disease to reduce the inflammation that causes flare symptoms — including... ### Ezetimibe **Generic:** ezetimibe Findability: 90/100 | Insurance: $0–$15 | Cash: $10–$50 What Is Ezetimibe? Ezetimibe is a prescription cholesterol-lowering medication sold under the brand name Zetia. It belongs to a unique class of drugs called cholesterol absorption inhibitors — the only drug in its class on the market. FDA-approved in 2002 and launched in 2003, ezetimibe is one of the most commonly prescribed non-statin cholesterol drugs in the United States. Ezetimibe works in the small intestine to block the absorption of cholesterol from food and bile, reducing the amount... ### Famotidine **Generic:** famotidine Findability: 88/100 | Insurance: $0–$20 | Cash: $4–$89 What Is Famotidine? Famotidine is a histamine H2-receptor antagonist (H2 blocker) used to reduce stomach acid production. It is sold under brand names including Pepcid, Pepcid AC, Pepcid Complete, and Zantac 360. It is available both over the counter (OTC) in 10 mg and 20 mg doses, and by prescription in 20 mg and 40 mg doses, as well as an oral suspension and IV injection. Famotidine is FDA-approved for treatment of duodenal and gastric ulcers, gastroesophageal reflux disease (GERD), erosive... ### Farxiga **Generic:** dapagliflozin Findability: 85/100 | Insurance: $0–$100 | Cash: $288–$778 What Is Farxiga? Farxiga is the brand name for dapagliflozin, a once-daily oral medication made by AstraZeneca. It belongs to a class of drugs called SGLT2 inhibitors (sodium-glucose cotransporter 2 inhibitors). First FDA-approved on January 8, 2014, Farxiga has expanded its approvals over the years to address three distinct conditions: type 2 diabetes mellitus, heart failure, and chronic kidney disease. In April 2026, the FDA approved the first generic versions of dapagliflozin, making this... ### Feirza 1/20 28 Day **Generic:** norethindrone acetate / ethinyl estradiol / ferrous fumarate Findability: 78/100 | Insurance: $0–$20 | Cash: $9–$87 What Is Feirza 1/20? Feirza 1/20 is a combination oral contraceptive (birth control pill) manufactured by Xiromed LLC, introduced to the U.S. market in January 2025 under FDA ANDA202772. Each 28-day pack contains 21 active white-to-off-white tablets — each containing norethindrone acetate 1 mg and ethinyl estradiol 20 mcg — plus 7 brown placebo tablets containing 75 mg ferrous fumarate (iron). The iron placebo tablets contain no hormones and serve only to help patients maintain a consistent... ### Felbamate **Generic:** felbamate Findability: 68/100 | Insurance: $0–$60 | Cash: $55–$326 What Is Felbamate? Felbamate (brand name Felbatol) is a carbamate anticonvulsant medication approved by the FDA in 1993. It is used to treat severe, treatment-resistant epilepsy—specifically partial (focal) seizures in adults and adolescents 14 years and older, and as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome (LGS) in children ages 2–14. Felbamate is one of eight antiepileptic drugs specifically FDA-approved for LGS. Felbamate is strictly a last-resort... ### Femring **Generic:** Femring Findability: 55/100 | Shortage: monitoring | Insurance: $30–$75 | Cash: $895–$1,100 What Is Femring? Femring is a prescription estradiol acetate vaginal ring used to treat moderate-to-severe menopausal symptoms. Unlike low-dose vaginal estrogen products that only address local vaginal symptoms, Femring delivers systemic levels of estrogen, making it effective for both vasomotor symptoms (hot flashes and night sweats) and vulvar/vaginal atrophy (dryness, irritation, and painful intercourse). Each ring is inserted into the vagina and left in place for 3 months before being... ### Fenofibrate **Generic:** fenofibrate Findability: 78/100 | Insurance: $0–$30 | Cash: $10–$268 What Is Fenofibrate? Fenofibrate is a prescription medication belonging to the fibrate class of drugs, used to treat abnormal blood lipid levels. It is FDA-approved for adults with severe hypertriglyceridemia (very high triglycerides), primary hypercholesterolemia (elevated LDL cholesterol), and mixed dyslipidemia (a combination of high LDL, high triglycerides, and low HDL cholesterol). It has been available in the United States since the 1990s and is now widely available as a generic... ### Fiasp **Generic:** insulin aspart Findability: 35/100 | Shortage: active | Insurance: $0–$50 | Cash: $78–$388 What Is Fiasp? Fiasp is a brand-name ultra-rapid-acting insulin manufactured by Novo Nordisk. Its active ingredient is insulin aspart — the same molecule found in NovoLog — but with the addition of niacinamide (vitamin B3), which accelerates absorption, and L-arginine for stability. Fiasp was FDA-approved on September 29, 2017, for improving glycemic control in adults and children with diabetes mellitus. Fiasp appears in the bloodstream approximately 2.5 minutes after injection — about twice... ### Finacea **Generic:** azelaic acid Findability: 82/100 | Insurance: $5–$50 | Cash: $27–$607 What Is Finacea? Finacea is the brand name for azelaic acid 15% topical gel and foam, a prescription treatment for mild-to-moderate rosacea. Manufactured by LEO Pharma, it is FDA-approved to treat the inflammatory papules and pustules (red bumps) associated with rosacea. A generic version of the gel (azelaic acid 15% gel) is widely available from multiple manufacturers. Azelaic acid is a naturally occurring dicarboxylic acid found in grains like wheat and rye. At the 15% prescription... ### Finasteride **Generic:** finasteride Findability: 88/100 | Insurance: $0–$30 | Cash: $9–$47 What Is Finasteride? Finasteride is a prescription oral medication belonging to the class of 5-alpha-reductase inhibitors (5-ARIs). It is FDA-approved for two conditions: male pattern hair loss (androgenetic alopecia) at a 1 mg daily dose (brand name Propecia), and benign prostatic hyperplasia (BPH) at a 5 mg daily dose (brand name Proscar). Generic finasteride is widely available from multiple manufacturers. Finasteride was first approved by the FDA in 1992 for BPH (as Proscar) and in 1997... ### Fintepla **Generic:** fenfluramine Findability: 55/100 | Insurance: $0–$25/month | Cash: Specialty pricing What Is Fintepla? Fintepla (fenfluramine) is a prescription antiseizure medication approved by the FDA for the treatment of seizures associated with Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS) in patients 2 years of age and older. It is a cherry-flavored oral solution containing 2.2 mg/mL fenfluramine. Fintepla was first approved by the FDA for Dravet syndrome on June 25, 2020, and received a second approval for Lennox-Gastaut syndrome on March 28, 2022. It is manufactured and... ### Firvanq **Generic:** vancomycin Findability: 65/100 | Insurance: $0–$30 | Cash: $143–$593 What Is Firvanq? Firvanq is the brand name for vancomycin hydrochloride for oral solution, manufactured by Azurity Pharmaceuticals. FDA-approved in January 2018, it is the only FDA-approved liquid formulation of vancomycin — a glycopeptide antibiotic used to treat serious gram-positive bacterial infections of the intestinal tract. Firvanq comes as a powder kit that a pharmacist reconstitutes with a grape-flavored diluent to produce an oral solution in 25 mg/mL or 50 mg/mL... ### Flecainide **Generic:** flecainide Findability: 80/100 | Insurance: $0–$20 | Cash: $11–$94 What Is Flecainide? Flecainide acetate (brand name: Tambocor) is a Class IC antiarrhythmic agent used to prevent and treat dangerous heart rhythm disorders. FDA-approved since 1984, it works by blocking fast sodium channels in cardiac cells to slow and stabilize abnormal electrical conduction. The generic has been widely available since 2004. In 2023, flecainide was the 223rd most prescribed medication in the United States with over 1 million prescriptions. It is approved for paroxysmal... ### Flomax **Generic:** tamsulosin Findability: 82/100 | Insurance: $0–$15 | Cash: $5–$108 What Is Flomax (Tamsulosin)? Flomax is the brand name for tamsulosin hydrochloride, an FDA-approved medication used to treat the urinary symptoms of benign prostatic hyperplasia (BPH), also known as an enlarged prostate. It was first approved by the FDA in 1997 and belongs to the drug class known as alpha-1 adrenergic receptor blockers (alpha blockers). The brand-name Flomax has been discontinued in the United States; all prescriptions are now filled with generic tamsulosin, which is... ### Florical **Generic:** calcium carbonate and sodium fluoride Findability: 60/100 | Insurance: Not covered | Cash: $15–$75 What Is Florical? Florical is a brand-name dietary supplement manufactured by Mericon Industries, Inc. (Peoria, Illinois) that combines two active ingredients: sodium fluoride (3.75 mg fluoride per capsule) and calcium carbonate (145 mg calcium per capsule, from oyster shell). It is available over the counter in 100-capsule and 500-capsule bottles. Florical is most commonly recommended by ENT specialists (otolaryngologists) for the management of otosclerosis — a condition involving abnormal... ### Fluconazole **Generic:** fluconazole Findability: 90/100 | Insurance: $0–$30 | Cash: $4–$25 What Is Fluconazole? Fluconazole is a triazole antifungal medication used to treat and prevent a wide range of fungal infections. It is available as the brand-name drug Diflucan (manufactured by Pfizer) and as widely available generic fluconazole. The drug was first approved by the FDA on January 29, 1990, and has become one of the most prescribed antifungals in the world. The World Health Organization includes fluconazole on its Model List of Essential Medicines, recognizing its critical... ### Fluocinonide **Generic:** fluocinonide Findability: 80/100 | Insurance: $0–$30 | Cash: $23–$132 What Is Fluocinonide? Fluocinonide is a prescription-only high-potency topical corticosteroid used to treat inflammatory and itchy skin conditions. It is available in cream, gel, ointment, and topical solution formulations. The generic 0.05% forms are Class II (high potency), while the 0.1% cream (brand name Vanos) is Class I (super-high potency) — making it one of the stronger topical steroids on the market. It was first FDA-approved on June 30, 1971. Fluocinonide is prescribed for... ### Fluorouracil **Generic:** fluorouracil Findability: 40/100 | Shortage: active | Insurance: $0–$30 | Cash: $30–$365 What Is Fluorouracil? Fluorouracil — commonly abbreviated as 5-FU or 5-fluorouracil — is a pyrimidine analog antimetabolite chemotherapy drug that has been in clinical use since its initial FDA approval in 1962. It is one of the most widely prescribed chemotherapy agents in the world and remains a cornerstone of treatment for multiple solid tumor types. Fluorouracil is available in two distinct formulations: an intravenous (IV) injection (50 mg/mL, brand name Adrucil) used for systemic cancer... ### Fluoxetine/Olanzapine **Generic:** fluoxetine-olanzapine Findability: 60/100 | Insurance: $60–$80 | Cash: $86–$360 What Is Fluoxetine/Olanzapine (Symbyax)? Fluoxetine/Olanzapine — sold under the brand name Symbyax — is an FDA-approved combination prescription capsule that pairs two well-established psychiatric medications: fluoxetine (an SSRI antidepressant, the active ingredient in Prozac) and olanzapine (an atypical antipsychotic, the active ingredient in Zyprexa). Together, they form a fixed-dose combination that targets both the serotonin and dopamine systems in the brain. Symbyax holds the... ### Fluphenazine **Generic:** fluphenazine Findability: 72/100 | Insurance: $0–$30 | Cash: $22–$274 What Is Fluphenazine? Fluphenazine is a high-potency, first-generation (typical) antipsychotic medication in the phenothiazine drug class. It was FDA-approved in September 1959, making it one of the earliest antipsychotics approved in the United States, and is on the World Health Organization's List of Essential Medicines in its injectable form. Previously sold under the brand names Prolixin and Permitil (both discontinued), fluphenazine is now available only as a generic medication. It is... ### Flurazepam **Generic:** flurazepam Findability: 42/100 | Shortage: active | Insurance: $10–$30 | Cash: $144–$608 What Is Flurazepam? Flurazepam is a long-acting benzodiazepine hypnotic approved by the FDA for the short-term treatment of mild to moderate insomnia. Originally marketed as Dalmane by Roche Pharmaceuticals starting in 1968, it was one of the first benzodiazepine sleep medications brought to market. The brand name Dalmane has since been discontinued, and only generic flurazepam hydrochloride is available today. Flurazepam is indicated for patients with difficulty falling asleep, frequent... ### Fluticasone **Generic:** Fluticasone Findability: 68/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $8–$310 What Is Fluticasone? Fluticasone is a synthetic corticosteroid used to treat a wide range of inflammatory conditions. In its inhaled form, it serves as a controller medication for asthma and COPD, reducing airway inflammation to prevent attacks. As a nasal spray, it relieves symptoms of allergic and non-allergic rhinitis, nasal polyps, and chronic sinusitis. In topical forms, it treats eczema, atopic dermatitis, and other corticosteroid-responsive skin conditions. Fluticasone comes in two salt... ### Fluvoxamine XR **Generic:** Fluvoxamine XR Findability: 35/100 | Shortage: active | Insurance: $20–$75 | Cash: $75–$440 What Is Fluvoxamine XR? Fluvoxamine XR (extended-release) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Its generic name is Fluvoxamine Maleate Extended-Release, and it was previously sold under the brand name Luvox CR, which has since been discontinued. Fluvoxamine XR is FDA-approved to treat: Obsessive-Compulsive Disorder (OCD) in adults Social Anxiety Disorder (SAD) in adults It is also prescribed off-label for major depressive disorder, generalized anxiety... ### Focalin **Generic:** Focalin Findability: 38/100 | Shortage: active | Insurance: $15–$60 | Cash: $18–$52 What Is Focalin? Focalin (dexmethylphenidate) is a prescription stimulant medication used to treat ADHD in children (ages 6+) and adults. It contains only the pharmacologically active d-isomer of methylphenidate, which is responsible for the therapeutic effects. Originally manufactured by Novartis, Focalin is now produced by Sandoz. It's available in both immediate-release (Focalin) and extended-release (Focalin XR) formulations, with generics available from multiple manufacturers. Because... ### Focalin XR **Generic:** Focalin XR Findability: 35/100 | Shortage: active | Insurance: $10–$80 | Cash: $30–$580 What Is Focalin XR? Focalin XR (Dexmethylphenidate Hydrochloride extended-release) is a prescription CNS stimulant medication approved by the FDA for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. It is manufactured by Novartis Pharmaceuticals and is available in both brand-name and generic forms. Focalin XR is the extended-release version of Focalin, designed to be taken once daily in the morning. The capsules use a dual-bead technology... ### Follitropin Alfa **Generic:** follitropin alfa Findability: 42/100 | Shortage: active | Insurance: $0–$200 | Cash: $500–$1,500 What Is Follitropin Alfa (Gonal-F)? Follitropin alfa is a recombinant (laboratory-made) form of follicle-stimulating hormone (FSH), sold under the brand name Gonal-F by EMD Serono. First FDA-approved in 1997, it is one of the most widely prescribed injectable fertility medications in the world. It is used in women to induce ovulation, to stimulate the development of multiple follicles for IVF (in vitro fertilization) and other assisted reproductive technologies (ART), and in men to stimulate... ### Fondaparinux **Generic:** Fondaparinux Findability: 55/100 | Shortage: monitoring | Insurance: $20–$100 | Cash: $83–$315 What Is Fondaparinux? Fondaparinux is a synthetic selective Factor Xa inhibitor used as an anticoagulant (blood thinner) to prevent and treat blood clots. It's approved for preventing deep vein thrombosis (DVT) in patients undergoing hip, knee, or abdominal surgery, and for treating acute DVT and pulmonary embolism. Unlike heparin, Fondaparinux is given as a once-daily subcutaneous injection and does not require routine blood monitoring. The brand name is Arixtra, but generic versions are... ### Forfivo XL **Generic:** bupropion hydrochloride Findability: 55/100 | Insurance: $0–$80 | Cash: $132–$566 What Is Forfivo XL? Forfivo XL is a brand-name prescription antidepressant manufactured by Almatica Pharma, containing bupropion hydrochloride in a 450 mg extended-release tablet taken once daily. It is the only commercially available single-tablet formulation of bupropion at the maximum approved 450 mg daily dose. The FDA first approved bupropion in 1985 under the Wellbutrin brand; Forfivo XL was developed specifically to provide the 450 mg dose in a single convenient tablet for patients who... ### Forteo **Generic:** teriparatide Findability: 45/100 | Insurance: $4–$200 | Cash: $1,035–$5,400 What Is Forteo (Teriparatide)? Forteo is the brand name for teriparatide, a prescription injectable medication used to treat severe osteoporosis in adults at high risk for fractures. It is manufactured by Eli Lilly and Company and was first FDA-approved in November 2002. FDA-approved generic teriparatide has been available since November 2023 from manufacturers including Teva and Apotex. Teriparatide is a synthetic (recombinant) version of the first 34 amino acids of human parathyroid hormone... ### Fosfomycin **Generic:** fosfomycin tromethamine Findability: 68/100 | Insurance: $10–$50 | Cash: $33–$110 What Is Fosfomycin? Fosfomycin (brand name Monurol) is a broad-spectrum antibiotic used to treat urinary tract infections (UTIs). It belongs to the phosphonic acid antibiotic class — a unique category structurally unrelated to all other antibiotic classes, including penicillins, cephalosporins, fluoroquinolones, and sulfonamides. This structural uniqueness means bacteria resistant to those common antibiotics often remain susceptible to fosfomycin. The FDA-approved oral formulation (fosfomycin... ### Foundayo **Generic:** orforglipron Findability: 45/100 | Insurance: $25–$50 | Cash: $149–$299 What Is Foundayo? Foundayo (orforglipron) is an oral prescription medication approved by the FDA on April 1, 2026 for chronic weight management in adults. Made by Eli Lilly, it is the first small-molecule, non-peptide GLP-1 receptor agonist approved for weight loss — and the only GLP-1 pill that can be taken at any time of day without food or water restrictions. Foundayo belongs to the same class of medications as Ozempic, Wegovy, and Zepbound, but its unique small-molecule structure allows... ### Furosemide **Generic:** furosemide Findability: 90/100 | Insurance: $0–$10 | Cash: $2–$25 What Is Furosemide? Furosemide is a loop diuretic—commonly called a "water pill"—used to treat fluid retention (edema) and high blood pressure. Sold under the brand name Lasix, it has been in clinical use since 1966 and is on the World Health Organization's List of Essential Medicines. In 2023, furosemide was the 29th most commonly prescribed medication in the United States with over 19 million prescriptions dispensed. Furosemide is FDA-approved to treat edema caused by congestive heart... ### Fyremadel **Generic:** ganirelix acetate Findability: 50/100 | Insurance: $0–$50 | Cash: $150–$250 What Is Fyremadel? Fyremadel is the brand name for ganirelix acetate, an injectable GnRH antagonist (gonadotropin-releasing hormone antagonist) manufactured by Ferring Pharmaceuticals and manufactured by Sun Pharmaceutical Industries. It is supplied as a prefilled, single-use sterile syringe containing 250 mcg of ganirelix acetate in 0.5 mL of solution, intended for subcutaneous (under-the-skin) injection. Ganirelix acetate was originally approved by the FDA in 1999 under the brand name... ### Gabapentin **Generic:** gabapentin Findability: 82/100 | Insurance: $0–$15 | Cash: $2–$90 What Is Gabapentin? Gabapentin is a prescription anticonvulsant medication first approved by the FDA in 1993. It is sold under the brand names Neurontin (immediate-release), Gralise (extended-release for PHN), and Horizant (extended-release for RLS and PHN). Generic gabapentin has been available since 2004 and is manufactured by many companies. Gabapentin is FDA-approved for three indications: partial-onset seizures (as adjunctive therapy in adults and children ages 3 and older), postherpetic... ### Ganciclovir **Generic:** ganciclovir Findability: 62/100 | Insurance: $0–$75 | Cash: $40–$570 What Is Ganciclovir? Ganciclovir is a synthetic antiviral medication in the nucleoside analogue class — the same family as acyclovir — but with significantly greater activity against cytomegalovirus (CMV). It was first approved by the FDA in 1988-1989 and remains a cornerstone treatment for CMV disease in immunocompromised patients. Ganciclovir is available in two distinct formulations in the United States: Cytovene-IV — an intravenous injection (500 mg lyophilized powder vial) used to treat... ### Ganirelix **Generic:** Ganirelix Findability: 50/100 | Shortage: active | Insurance: $0–$75 | Cash: $44–$250 What Is Ganirelix? Ganirelix (also known as Ganirelix Acetate) is a synthetic injectable medication classified as a GnRH antagonist (Gonadotropin-Releasing Hormone Antagonist). It is FDA-approved to prevent premature luteinizing hormone (LH) surges in women undergoing controlled ovarian hyperstimulation as part of in vitro fertilization (IVF) and other assisted reproductive technology (ART) procedures. By blocking premature ovulation, Ganirelix allows fertility specialists to precisely time... ### Gemtesa **Generic:** vibegron Findability: 78/100 | Insurance: $10–$200 | Cash: $470–$692 What Is Gemtesa? Gemtesa is a brand-name prescription medication containing the active ingredient vibegron. It is a once-daily 75 mg tablet used to treat overactive bladder (OAB) in adults. Manufactured by Sumitomo Pharma America, Gemtesa was first FDA-approved in December 2020 and commercially launched in the United States in April 2021. Gemtesa has two FDA-approved indications: (1) OAB with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults, and (2) OAB in adult... ### Gentamicin **Generic:** gentamicin Findability: 75/100 | Insurance: $0–$20 | Cash: $10–$100 What Is Gentamicin? Gentamicin is an aminoglycoside antibiotic derived from Micromonospora purpurea, a soil-dwelling actinomycete bacterium. It has been a cornerstone of infectious disease treatment since its introduction in the 1960s, and remains one of the most important antibiotics for treating serious gram-negative bacterial infections. Gentamicin is available in several formulations: injectable (IV/IM) for systemic infections, ophthalmic solution and ointment (Gentak) for bacterial eye... ### Genvoya **Generic:** elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide Findability: 65/100 | Insurance: $0–$200 | Cash: $4,061–$5,146 What Is Genvoya? Genvoya is a prescription antiretroviral medication used to treat HIV-1 (human immunodeficiency virus type 1) in adults and adolescents. It is a fixed-dose combination tablet containing four medications: elvitegravir (150 mg), cobicistat (150 mg), emtricitabine (200 mg), and tenofovir alafenamide (10 mg). Manufactured by Gilead Sciences and FDA-approved in November 2015, Genvoya is taken as one tablet once daily with food. Genvoya is FDA-approved for two patient populations:... ### Gimoti **Generic:** metoclopramide Findability: 45/100 | Insurance: $0–$20 | Cash: $2,499–$2,825 What Is Gimoti? Gimoti is the brand name for metoclopramide nasal spray, the only FDA-approved nasal spray formulation of metoclopramide. It is manufactured by Patheon (a Thermo Fisher division) for Evoke Pharma, Inc. and received FDA approval in 2020 (NDA 209388). The active ingredient, metoclopramide, has been used in the United States since 1979 in oral and injectable forms. Gimoti is FDA-approved for the relief of symptoms in adults with acute and recurrent diabetic gastroparesis — a... ### Givlaari **Generic:** givosiran Findability: 38/100 | Insurance: $0–$5,000+/month | Cash: $39,000–$43,000/vial What Is Givlaari? Givlaari (givosiran) is an FDA-approved prescription medication for the treatment of adults with acute hepatic porphyria (AHP), a group of rare genetic diseases that cause life-threatening neurovisceral attacks. It was developed by Alnylam Pharmaceuticals and approved by the FDA on November 20, 2019 — becoming the first disease-modifying therapy to target the root cause of AHP at the genetic level. AHP encompasses four types: acute intermittent porphyria (AIP), variegate... ### Glucophage XR **Generic:** metformin hydrochloride extended-release Findability: 75/100 | Insurance: $0–$20 | Cash: $11–$50 What Is Glucophage XR? Glucophage XR is the brand name for metformin hydrochloride extended-release tablets. It is a biguanide-class oral antidiabetic medication FDA-approved as a first-line treatment for type 2 diabetes mellitus in adults. The extended-release formulation delivers metformin gradually over 8-10 hours, allowing once-daily dosing and reducing the gastrointestinal side effects that some patients experience with the immediate-release version. The original brand-name Glucophage XR... ### Glutamine **Generic:** glutamine Findability: 42/100 | Insurance: $10–$150 | Cash: $1,013–$3,471 What Is Glutamine (Endari)? Glutamine, sold under the brand name Endari, is an FDA-approved prescription medication for sickle cell disease (SCD). It is a pharmaceutical-grade form of L-glutamine, an amino acid that the body normally produces but that sickle red blood cells have difficulty utilizing effectively. Endari was approved by the FDA in July 2017 — the first new treatment for sickle cell disease in nearly 20 years and the first treatment ever approved specifically for pediatric SCD... ### Glycopyrronium **Generic:** glycopyrronium Findability: 72/100 | Insurance: $0–$50 | Cash: $13–$600 What Is Glycopyrronium? Glycopyrronium (also known as glycopyrrolate in the U.S.) is a synthetic anticholinergic medication belonging to the quaternary ammonium compound class. It works by competitively blocking muscarinic receptors throughout the body, reducing gland secretions, relaxing airway smooth muscle, and decreasing gastrointestinal motility. One of its most important properties is that it does not cross the blood-brain barrier, which means it produces peripheral anticholinergic... ### Gomekli **Generic:** mirdametinib Findability: 40/100 | Insurance: $0 copay (eligible patients) | Cash: Contact specialty pharmacy What Is Gomekli? Gomekli (mirdametinib) is a prescription MEK inhibitor approved by the FDA on February 11, 2025 for adults and children aged 2 years and older with neurofibromatosis type 1 (NF1) who have symptomatic plexiform neurofibromas (PN) that cannot be completely removed by surgery. It is manufactured by SpringWorks Therapeutics, Inc. and received Priority Review, Fast Track, and Orphan Drug designations from the FDA. Neurofibromatosis Type 1 (NF1) is a rare genetic disorder affecting... ### Gonal F **Generic:** Gonal F Findability: 55/100 | Shortage: monitoring | Insurance: $50–$500+ | Cash: $900–$6,000 What Is Gonal F? Gonal F (Follitropin Alfa) is a recombinant human follicle-stimulating hormone (r-hFSH) manufactured by EMD Serono. It is a fertility medication used to stimulate the growth and maturation of ovarian follicles in women undergoing fertility treatment, including ovulation induction and assisted reproductive technology (ART) cycles such as IVF. Gonal F is also approved to induce spermatogenesis in men with hypogonadotropic hypogonadism. Gonal F is administered as a subcutaneous... ### Griseofulvin **Generic:** griseofulvin Findability: 62/100 | Insurance: $0–$30 | Cash: $80–$352 What Is Griseofulvin? Griseofulvin is an oral antifungal medication used to treat dermatophyte (ringworm) infections — fungal infections of the skin, hair, and nails caused by Trichophyton, Microsporum, or Epidermophyton species. Discovered in 1939 from the soil mold Penicillium griseofulvum, it has been in medical use since the late 1950s and remains on the World Health Organization's List of Essential Medicines. Griseofulvin is the recommended first-line treatment for tinea capitis (scalp... ### Guanfacine **Generic:** guanfacine Findability: 82/100 | Insurance: $0–$30 | Cash: $10–$220 What Is Guanfacine? Guanfacine is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure (hypertension). It is sold under the brand name Intuniv (extended-release) and was formerly available as Tenex (immediate-release). Generic versions of both formulations are widely available. Guanfacine is a non-stimulant and is not a DEA-scheduled controlled substance. This distinguishes it from stimulant ADHD medications like amphetamines... ### Gynazole-1 **Generic:** butoconazole nitrate Findability: 60/100 | Insurance: $25–$60 | Cash: $94–$169 What Is Gynazole-1? Gynazole-1 is the brand name for butoconazole nitrate 2% vaginal cream, USP — a single-dose prescription antifungal medication used to treat vaginal yeast infections. The "1" in its name refers to its single-dose format: one pre-filled disposable applicator delivers the full 5-gram dose (100 mg of butoconazole nitrate) intravaginally. Gynazole-1 is FDA-approved for the local treatment of vulvovaginal candidiasis (VVC) — vaginal yeast infections caused by Candida species.... ### Hadlima **Generic:** Hadlima Findability: 40/100 | Shortage: active | Insurance: $0–$50 | Cash: $1,000–$1,500 What Is Hadlima? Hadlima (adalimumab-bwwd) is a biosimilar to Humira, manufactured by Organon. It is a TNF (tumor necrosis factor) blocker used to treat a range of autoimmune and inflammatory conditions. Hadlima is FDA-approved for moderately to severely active rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease (adults and pediatric patients 6+), ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, juvenile idiopathic arthritis (ages 2+), and... ### Halcinonide **Generic:** halcinonide Findability: 78/100 | Insurance: $10–$60 | Cash: $93–$607 What Is Halcinonide? Halcinonide is a prescription topical corticosteroid used to treat inflammatory and itchy skin conditions that respond to steroid treatment. It is sold under the brand name Halog and is classified as a Class II (high potency) topical steroid in the U.S. classification system — one tier below the strongest available topical steroids like clobetasol propionate. FDA-approved since November 27, 1974, halcinonide has a long track record of clinical use for conditions including... ### Halcion **Generic:** triazolam Findability: 45/100 | Insurance: $5–$20 | Cash: $4–$50 What Is Halcion (Triazolam)? Halcion is the brand name for triazolam, a prescription sleep medication approved by the FDA in 1982. It belongs to the triazolobenzodiazepine subclass of benzodiazepines — a group of medications that enhance the brain's natural calming neurotransmitter, GABA. Halcion is FDA-approved for the short-term treatment of insomnia in adults, typically used for 7 to 10 days. Triazolam is one of the fastest-acting and shortest-acting benzodiazepines available, with a... ### Haloette **Generic:** etonogestrel/ethinyl estradiol Findability: 72/100 | Insurance: $0–$30 | Cash: $85–$199 What Is Haloette? Haloette is a prescription contraceptive vaginal ring that prevents pregnancy. It is an FDA-approved branded-generic version of NuvaRing, approved in 2022 and manufactured by Mayne Pharma in collaboration with Mithra. It contains two hormones — etonogestrel (a progestin) and ethinyl estradiol (a synthetic estrogen) — embedded in a flexible, soft plastic ring approximately 54 mm in diameter. Haloette is used by inserting one ring into the vagina for three consecutive weeks... ### Heather 28 Day **Generic:** norethindrone Findability: 78/100 | Insurance: $0–$15 | Cash: $15–$94 What Is Heather 28 Day? Heather 28 Day is a brand-name oral contraceptive containing norethindrone 0.35 mg as its only active ingredient. It is manufactured by Glenmark Pharmaceuticals Inc. and belongs to the class of progestin-only oral contraceptives, commonly called the "mini-pill" (POP). Unlike combination birth control pills that contain both an estrogen and a progestin, Heather 28 Day contains only a synthetic progestin hormone. Each 28-tablet blister pack contains all active tablets —... ### Hemady **Generic:** dexamethasone Findability: 50/100 | Insurance: $0–$100 | Cash: $240–$710 What Is Hemady? Hemady is the brand name for dexamethasone 20 mg oral tablets, manufactured by Edenbridge Pharmaceuticals, LLC. It was FDA-approved in 2019 and is the only dexamethasone formulation specifically indicated for use in combination with other anti-myeloma products to treat adults with multiple myeloma. The key innovation of Hemady is its high-strength 20 mg tablet. Before Hemady, patients needed five to ten 4 mg generic dexamethasone tablets per dose — Hemady reduces this to one... ### Hemgenix Kit 126-130 kg **Generic:** etranacogene dezaparvovec-drlb Findability: 20/100 | Shortage: active | Insurance: $0 for most commercially insured | Cash: ~$3.5 million What Is Hemgenix Kit 126-130 kg? Hemgenix (etranacogene dezaparvovec-drlb) is a one-time gene therapy for adults with hemophilia B (congenital Factor IX deficiency), approved by the FDA on November 22, 2022. It is the first and currently the only FDA-approved gene therapy for hemophilia B. The Kit 126-130 kg designation refers to the patient-specific, weight-based dosing kit dispensed for patients in this weight range. Manufactured and commercialized by CSL Behring (developed originally by... ### Heparin **Generic:** heparin sodium Findability: 40/100 | Shortage: active | Insurance: $0–$20 | Cash: $40–$70 What Is Heparin? Heparin is an injectable anticoagulant (blood thinner) that prevents and treats dangerous blood clots. It has been used in medicine since the 1930s, making it one of the oldest and most established medications in modern healthcare. First discovered in 1916, heparin is derived from the intestinal mucosa of pigs and is given by intravenous (IV) infusion or subcutaneous injection — it cannot be taken orally because it is not absorbed through the digestive tract. Heparin (also... ### Herpesvirus 1, Human **Generic:** acyclovir Findability: 65/100 | Shortage: active | Insurance: $0–$30 | Cash: $10–$217 What Is Herpesvirus 1, Human (HSV-1)? Herpesvirus 1, Human — commonly called HSV-1 or herpes simplex virus type 1 — is one of the most prevalent viral infections in the world. The World Health Organization estimates that approximately 3.7 billion people under age 50 (67% of the global population) are infected with HSV-1. Most people acquire it in childhood through non-sexual oral contact. The virus is a member of the Herpesviridae family and is characterized by its ability to establish... ### Histrelin **Generic:** histrelin acetate Findability: 40/100 | Shortage: active | Insurance: $0–$7,500 | Cash: $45,000–$53,000 What Is Histrelin? Histrelin acetate (brand name Supprelin LA) is a prescription medication used to treat central precocious puberty (CPP) in children. CPP is a medical condition in which puberty begins too early — before age 8 in girls and age 9 in boys. Left untreated, early puberty can cause premature bone growth and early fusion of growth plates, potentially leading to shorter adult stature. Histrelin is classified as a gonadotropin-releasing hormone (GnRH) agonist. It works by initially... ### Humalog **Generic:** insulin lispro Findability: 72/100 | Shortage: resolved | Insurance: $0–$35 | Cash: $25–$90 What Is Humalog? Humalog is the brand name for insulin lispro, a rapid-acting insulin analog manufactured by Eli Lilly and Company. First approved by the FDA in 1996, it was the first rapid-acting insulin analog available in the United States. Today, it is one of the most widely prescribed insulins worldwide. Humalog is used to control blood sugar spikes that occur after meals in people with Type 1 and Type 2 diabetes. It begins working within approximately 15 minutes of injection, peaks at... ### Humatin **Generic:** paromomycin Findability: 35/100 | Shortage: active | Insurance: $20–$100 | Cash: $2,700–$6,150 What Is Humatin? Humatin is the brand name for paromomycin sulfate, an aminoglycoside antibiotic manufactured by Waylis Therapeutics LLC. It is available as 250 mg oral capsules and is FDA-approved for the treatment of intestinal amebiasis (acute and chronic) and as adjunctive therapy in the management of hepatic coma. Unlike most aminoglycoside antibiotics, paromomycin is minimally absorbed from the gastrointestinal tract — nearly 100% of an oral dose is excreted unchanged in the stool. This... ### Humulin N **Generic:** insulin nph Findability: 78/100 | Insurance: $0–$35 | Cash: $25–$86 What Is Humulin N? Humulin N is a brand-name intermediate-acting human insulin made by Eli Lilly and Company. Its generic name is insulin isophane human — commonly called NPH insulin (Neutral Protamine Hagedorn). First approved by the FDA in 1982, Humulin N is one of the most widely used insulin formulations in the United States for managing both Type 1 and Type 2 diabetes. Available as a 10 mL multi-dose vial and a 3 mL KwikPen prefilled injector, Humulin N is used as a basal (background)... ### Hycamtin **Generic:** topotecan Findability: 60/100 | Insurance: $50–$75 | Cash: $122–$1,250+ What Is Hycamtin? Hycamtin is the brand name for topotecan hydrochloride, a prescription chemotherapy medication first approved by the FDA in 1996. It belongs to a class of drugs called topoisomerase I inhibitors — agents that interfere with the DNA copying process inside cancer cells, causing them to die. Hycamtin is derived from camptothecin, a natural compound originally extracted from the bark of the Camptotheca acuminata ("Happy Tree") plant. Hycamtin is FDA-approved for three specific... ### Hydrochlorothiazide/Lisinopril **Generic:** hydrochlorothiazide/lisinopril Findability: 82/100 | Insurance: $0–$15 | Cash: $7–$54 What Is Hydrochlorothiazide/Lisinopril? Hydrochlorothiazide/Lisinopril is a fixed-dose combination prescription tablet used to treat hypertension (high blood pressure) in adults. It pairs lisinopril — an angiotensin-converting enzyme (ACE) inhibitor — with hydrochlorothiazide (HCTZ), a thiazide diuretic ("water pill"). The two drugs lower blood pressure through complementary mechanisms, making the combination more effective than either drug alone for many patients. Sold under the brand names... ### Hydrocortisone **Generic:** hydrocortisone Findability: 45/100 | Shortage: active | Insurance: $0–$20 | Cash: $15–$80 What Is Hydrocortisone? Hydrocortisone is the pharmaceutical form of cortisol — the body's primary stress hormone, produced naturally by the adrenal glands. It belongs to the glucocorticoid (corticosteroid) drug class and is used both as hormone replacement therapy and as an anti-inflammatory and immunosuppressive agent. The brand-name version of oral hydrocortisone tablets is Cortef (Pfizer). Injectable hydrocortisone is marketed as Solu-Cortef. A pediatric sprinkle capsule formulation is... ### Hydrocortisone/Iodoquinol **Generic:** hydrocortisone/iodoquinol Findability: 72/100 | Insurance: $0–$50 | Cash: $45–$839 What Is Hydrocortisone/Iodoquinol? Hydrocortisone/Iodoquinol is a prescription topical combination medication used to treat inflammatory skin conditions complicated by bacterial or fungal infection. It contains two active ingredients: hydrocortisone, a low-potency corticosteroid that reduces redness and itching, and iodoquinol, a broad-spectrum antifungal and antibacterial agent. Brand names include Alcortin, Alcortin A, Vytone, Dermazene, Corti-Sav, and Iodoquimez. It is available as a cream... ### Hydrocortisone/Pramoxine **Generic:** hydrocortisone/pramoxine Findability: 72/100 | Insurance: $10–$50 | Cash: $43–$430 What Is Hydrocortisone/Pramoxine? Hydrocortisone/Pramoxine is a prescription combination topical medication that combines two active ingredients: hydrocortisone (a low-potency corticosteroid) and pramoxine hydrochloride (a local anesthetic). FDA-approved since August 1976, it is available under more than 18 brand names including Analpram-HC, Pramosone, Proctofoam HC, and Epifoam. This dual-action topical is used primarily to treat conditions causing inflammation, pain, and itching in the... ### Hydroquinone **Generic:** hydroquinone Findability: 72/100 | Insurance: $0–$30 | Cash: $20–$125 What Is Hydroquinone? Hydroquinone is a topical depigmenting agent — a cream, gel, emulsion, or solution applied directly to the skin to reduce dark patches caused by excess melanin. It is the most widely prescribed skin-lightening medication in the United States and is considered the gold standard for treating melasma, age spots, freckles, and post-inflammatory hyperpigmentation (PIH). Hydroquinone is available at 2% and 4% concentrations with a prescription, and in custom compounded... ### Hydroxychloroquine **Generic:** hydroxychloroquine Findability: 78/100 | Insurance: $0–$30 | Cash: $15–$200 What Is Hydroxychloroquine? Hydroxychloroquine is an oral prescription medication classified as both a disease-modifying antirheumatic drug (DMARD) and an antimalarial. It is sold under the brand names Plaquenil and Sovuna, and is widely available as a generic. FDA-approved since 1955, it is on the World Health Organization's List of Essential Medicines. Hydroxychloroquine is used to treat systemic lupus erythematosus (SLE), discoid lupus erythematosus (DLE), rheumatoid arthritis (RA),... ### Hydroxyzine **Generic:** hydroxyzine Findability: 72/100 | Insurance: $0–$20 | Cash: $15–$45 What Is Hydroxyzine? Hydroxyzine is a first-generation antihistamine in the piperazine chemical family, used as an anxiolytic, antipruritic, and sedative. Originally approved in 1956, it is one of the oldest psychiatric and allergy medications still in widespread use — and one of the most widely prescribed drugs in the United States, with over 15 million prescriptions written annually. It was formerly sold under the brand names Atarax (hydroxyzine hydrochloride) and Vistaril (hydroxyzine... ### Hyrimoz **Generic:** adalimumab-adaz Findability: 62/100 | Insurance: $0–$100/mo | Cash: $1,300–$6,500/mo What Is Hyrimoz? Hyrimoz (adalimumab-adaz) is an FDA-approved biologic medication and biosimilar to Humira (adalimumab), the world's best-selling drug. Manufactured by Sandoz Inc. (a Novartis company), Hyrimoz launched in the United States on July 1, 2023, following FDA approval in October 2018 for the original formulation and March 2023 for the high-concentration citrate-free version. Hyrimoz is approved for nine inflammatory and autoimmune conditions: rheumatoid arthritis (RA), juvenile... ### Ibalizumab **Generic:** ibalizumab-uiyk Findability: 45/100 | Insurance: $0–$0+ copay | Cash: $3,659–$9,000+/month What Is Ibalizumab (Trogarzo)? Ibalizumab (brand name Trogarzo) is a humanized monoclonal antibody used to treat HIV-1 infection. It is classified as a CD4-directed post-attachment HIV-1 inhibitor—a type of entry inhibitor that works by binding to the CD4 receptor on immune cells and preventing HIV from gaining entry. The FDA approved ibalizumab on March 6, 2018, making it the first monoclonal antibody approved to treat HIV and the first HIV therapy with a new mechanism of action approved in... ### Ibsrela **Generic:** Ibsrela Findability: 60/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $2,000–$2,500 What Is Ibsrela? Ibsrela (Tenapanor) is an FDA-approved prescription medication used to treat irritable bowel syndrome with constipation (IBS-C) in adults. It belongs to a class of drugs called sodium/hydrogen exchanger 3 (NHE3) inhibitors. Ibsrela is the first and only NHE3 inhibitor approved for IBS-C, offering a unique mechanism of action compared to other treatments on the market. The active ingredient, Tenapanor Hydrochloride, is also marketed under the brand name Xphozah for a separate... ### Ilevro **Generic:** nepafenac Findability: 75/100 | Insurance: $52–$80 | Cash: $149–$482 What Is Ilevro? Ilevro is the brand name for nepafenac 0.3% ophthalmic suspension — a prescription eye drop used to treat pain and inflammation following cataract surgery. It is manufactured by Harrow (Harrow IP, LLC) and has been on the U.S. market since January 2013. Ilevro comes in sterile 1.7 mL and 3 mL bottles. Ilevro belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) and is specifically formulated for topical ophthalmic use. Its FDA-approved indication is for the... ### Imipenem/Cilastatin **Generic:** imipenem/cilastatin Findability: 25/100 | Shortage: active | Insurance: $0–$50 | Cash: $46–$303 What Is Imipenem/Cilastatin? Imipenem/Cilastatin (brand name Primaxin) is a combination carbapenem antibiotic — the first carbapenem ever approved by the FDA (1985). It is used to treat serious and life-threatening bacterial infections caused by a broad spectrum of gram-positive, gram-negative, and anaerobic organisms, including many drug-resistant bacteria. The drug is administered intravenously (IV) or by intramuscular (IM) injection, almost always in a hospital, infusion center, or through... ### Imipramine **Generic:** Imipramine Findability: 78/100 | Insurance: $0–$15 | Cash: $8–$50 What Is Imipramine? Imipramine is a tricyclic antidepressant (TCA) that has been used since the late 1950s. It is FDA-approved for treating major depressive disorder in adults and nocturnal enuresis (bedwetting) in children aged 6 and older. Originally marketed as Tofranil by Novartis, it is now widely available as an affordable generic. Beyond its approved uses, Imipramine is also prescribed off-label for panic disorder, chronic neuropathic pain, overactive bladder, PTSD, and anxiety... ### Imiquimod **Generic:** imiquimod Findability: 72/100 | Insurance: $0–$30 | Cash: $30–$220 What Is Imiquimod? Imiquimod is a prescription topical cream used to treat external genital and perianal warts (condyloma acuminata), actinic keratosis (precancerous sun-damaged skin), and superficial basal cell carcinoma (a type of skin cancer). It belongs to a class of medications called immune response modifiers and was first FDA-approved in 1997. Imiquimod is available as a cream in three strengths: 2.5%, 3.75%, and 5%. The most commonly prescribed is the 5% generic cream, which is... ### Imitrex **Generic:** sumatriptan Findability: 88/100 | Insurance: $0–$15 | Cash: $10–$88 What Is Imitrex? Imitrex is the brand name for sumatriptan succinate, a prescription migraine medication first approved by the FDA in 1992. It was the first triptan ever brought to market and remains one of the most widely prescribed acute migraine treatments in the United States. Generic versions of sumatriptan have been available since 2008 when the original patent expired, making it one of the most affordable migraine medications available today. Imitrex belongs to the drug class known as... ### Imuran **Generic:** azathioprine Findability: 65/100 | Shortage: active | Insurance: $5–$25 | Cash: $13–$70 What Is Imuran (Azathioprine)? Imuran is the brand name for azathioprine, an immunosuppressant medication in the class of purine antimetabolites. It has been used in medicine since the 1960s and remains a cornerstone therapy for preventing organ transplant rejection and managing autoimmune conditions. It is available as a generic (multiple manufacturers) and as brand-name Imuran (50 mg tablets) and Azasan (75 mg and 100 mg tablets). The FDA approved azathioprine in March 1968 for two... ### Imvexxy 4 mcg Starter Pack **Generic:** estradiol vaginal inserts Findability: 52/100 | Insurance: $35–$75 | Cash: $404–$647 What Is Imvexxy 4 mcg Starter Pack? Imvexxy (estradiol vaginal inserts) is a prescription local estrogen therapy approved by the FDA in 2018 to treat moderate to severe dyspareunia — painful sexual intercourse — which is a common symptom of vulvar and vaginal atrophy (VVA) due to menopause. The 4 mcg starter pack contains 18 inserts designed for the initial loading phase of treatment. Imvexxy is a small, soft, light-pink, tear-shaped softgel that is placed directly into the vagina without an... ### Incassia 28 Day **Generic:** norethindrone Findability: 78/100 | Insurance: $0–$10 | Cash: $18–$65 What Is Incassia 28 Day? Incassia 28 Day is a prescription progestin-only oral contraceptive — commonly called a "mini-pill" — containing 0.35 mg of norethindrone. It is manufactured by Aurobindo Pharma and comes in blister packs of 28 tablets, all of which are active (no placebo pills). It is taken once daily at the same time every day, continuously with no break between packs. Unlike combined oral contraceptives, Incassia contains no estrogen — making it an important option for patients who... ### Incruse Ellipta **Generic:** umeclidinium Findability: 72/100 | Insurance: $20–$60 | Cash: $350–$415 What Is Incruse Ellipta? Incruse Ellipta is the brand name for umeclidinium inhalation powder, a prescription maintenance inhaler manufactured by GlaxoSmithKline (GSK) and FDA-approved since 2013. It is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in adults with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Incruse Ellipta belongs to the drug class known as long-acting muscarinic antagonists (LAMAs) — also... ### Indomethacin **Generic:** indomethacin Findability: 65/100 | Insurance: $0–$20 | Cash: $5–$50 What Is Indomethacin? Indomethacin is a potent prescription nonsteroidal anti-inflammatory drug (NSAID) that has been used in medicine since 1963. Originally marketed as Indocin, it is now available only as a generic in the United States. It belongs to the indoleacetic acid class of NSAIDs and is one of the most powerful anti-inflammatory agents available by prescription. The FDA has approved indomethacin to treat moderate to severe acute pain, rheumatoid arthritis, osteoarthritis, ankylosing... ### Ingrezza **Generic:** valbenazine Findability: 55/100 | Insurance: $0–$10 | Cash: $7,900–$8,700 What Is Ingrezza? Ingrezza (generic name: valbenazine) is a prescription medication used to treat two movement disorders in adults: tardive dyskinesia (TD) and chorea associated with Huntington's disease (HD). Made by Neurocrine Biosciences, Ingrezza was the first drug ever FDA-approved specifically for tardive dyskinesia, receiving that approval in April 2017. It received its second approval for HD chorea in August 2023. Tardive dyskinesia is a neurological condition causing repetitive,... ### Insulin Analog, Aspart Mixed **Generic:** insulin aspart protamine and insulin aspart Findability: 38/100 | Shortage: active | Insurance: $0–$35 | Cash: $70–$140 What Is Insulin Analog, Aspart Mixed (NovoLog Mix 70/30)? Insulin Analog, Aspart Mixed — sold under the brand name NovoLog Mix 70/30 — is a premixed biphasic insulin manufactured by Novo Nordisk. It was first approved by the FDA in 2001 and combines 70% insulin aspart protamine (intermediate-acting) with 30% soluble insulin aspart (rapid-acting). It is indicated to improve glycemic control in adults with type 1 and type 2 diabetes mellitus. The premixed formulation is designed for twice-daily... ### Insulin Analog, Degludec **Generic:** Insulin Analog, Degludec Findability: 58/100 | Shortage: monitoring | Insurance: $0–$35 | Cash: $300–$500 What Is Insulin Analog, Degludec? Insulin Degludec (brand name Tresiba) is an ultra-long-acting basal insulin analog manufactured by Novo Nordisk. It is FDA-approved to improve blood sugar control in adults with type 1 and type 2 diabetes, and in pediatric patients aged 1 year and older with type 1 diabetes. Tresiba is injected subcutaneously once daily and provides a flat, stable glucose-lowering effect lasting over 42 hours, allowing flexible dosing timing as long as there are at least 8... ### Insulin Analog, Lispro Mixed **Generic:** insulin lispro protamine/insulin lispro Findability: 55/100 | Shortage: active | Insurance: $0–$35 | Cash: $80–$280 What Is Insulin Analog, Lispro Mixed? Insulin Analog, Lispro Mixed is a premixed injectable insulin product that combines two forms of insulin lispro in fixed proportions. Sold under the Humalog Mix brand by Eli Lilly and Company, it is available in two formulations: Humalog Mix 75/25 (75% insulin lispro protamine and 25% insulin lispro) and Humalog Mix 50/50 (50% of each). Both are available as 10 mL vials and KwikPen prefilled injection pens. This medication is FDA-approved to improve blood... ### Insulin Glargine **Generic:** insulin glargine Findability: 45/100 | Shortage: active | Insurance: $0–$35 | Cash: $35–$360 What Is Insulin Glargine? Insulin Glargine is a long-acting basal insulin analog used to control blood sugar in people with Type 1 and Type 2 diabetes. Sold under brand names including Lantus, Toujeo, Basaglar, and Rezvoglar, it is injected once daily subcutaneously and provides a steady, peakless level of insulin coverage for approximately 24 hours — closely mimicking the natural basal insulin secretion of a healthy pancreas. Insulin Glargine is FDA-approved for adults with Type 1 and Type 2... ### Insulin Glargine-Yfgn **Generic:** insulin glargine-yfgn Findability: 45/100 | Shortage: active | Insurance: $0–$35 | Cash: $45–$150 What Is Insulin Glargine-Yfgn? Insulin glargine-yfgn is a long-acting biosimilar insulin analog used to control blood sugar in adults and children (ages 6+) with Type 1 diabetes, and in adults with Type 2 diabetes. It was originally marketed as Semglee by Biocon Biologics/Viatris and approved by the FDA on July 28, 2021 as the first interchangeable biosimilar insulin in US history. The Semglee brand was discontinued on December 31, 2025. As of January 2026, unbranded insulin glargine-yfgn is... ### Insulin, Human Isophane **Generic:** insulin isophane human Findability: 72/100 | Insurance: $0–$35 | Cash: $25–$158 What Is Insulin, Human Isophane? Insulin, human isophane — commonly known as NPH insulin — is an intermediate-acting human insulin used to improve blood sugar control in people with Type 1 and Type 2 diabetes mellitus. NPH stands for Neutral Protamine Hagedorn, named after the scientist who created this formulation in 1946. It is one of the oldest insulin preparations still in widespread use today and is included on the World Health Organization's List of Essential Medicines. NPH insulin is... ### Insulin, Regular, Human **Generic:** insulin, regular, human Findability: 72/100 | Shortage: resolved | Insurance: $0–$35 | Cash: $35–$100 What Is Insulin, Regular, Human? Insulin, Regular, Human — sold under the brand names Humulin R (Eli Lilly) and Novolin R (Novo Nordisk) — is a short-acting, synthetic human insulin used to lower blood glucose levels in people with diabetes mellitus. It is structurally identical to the insulin produced naturally by the human pancreas, created through recombinant DNA technology. Unlike rapid-acting insulin analogs (such as Humalog or NovoLog), regular human insulin has a slower onset of action... ### Integra F **Generic:** ferrous fumarate / folic acid Findability: 60/100 | Insurance: $0–$20 | Cash: $15–$30 What Is Integra F? Integra F is a brand-name prescription supplement manufactured by U.S. Pharmaceutical Corporation. Each capsule contains 125 mg of elemental iron (from Ferrous Fumarate and Polysaccharide Iron Complex), 1 mg of folic acid, 40 mg of Vitamin C, and 3 mg of Vitamin B3 (niacin). It is dispensed as maroon Vcaps capsules and is available by prescription only. Integra F is indicated for the treatment of iron deficiency anemia and folate deficiency anemia. It is also specifically... ### Intralipid **Generic:** lipid injectable emulsion Findability: 62/100 | Insurance: $0–$50 | Cash: $51–$315 What Is Intralipid? Intralipid is a brand-name intravenous fat emulsion manufactured by Fresenius Kabi. It is a sterile, milky white liquid composed of 100% soybean oil, emulsified with egg phospholipids and stabilized with glycerin for IV administration. Intralipid is the lipid component of parenteral nutrition (PN) — medical-grade IV feeding used when patients cannot absorb nutrition through the gastrointestinal tract. Intralipid has been in clinical use since 1962 in Europe and received... ### Intrarosa **Generic:** Intrarosa Findability: 55/100 | Shortage: monitoring | Insurance: $35–$75 | Cash: $288–$402 What Is Intrarosa and What Does It Do? Intrarosa (Prasterone) is a vaginal insert used to treat moderate to severe dyspareunia — painful sexual intercourse — caused by vulvar and vaginal atrophy (VVA) due to menopause. It contains 6.5 mg of Prasterone (also known as DHEA), which is inserted vaginally once daily at bedtime. Intrarosa helps restore vaginal tissue by converting locally into active hormones, relieving pain and discomfort associated with postmenopausal vaginal changes. ### Intuniv **Generic:** guanfacine extended-release Findability: 78/100 | Insurance: $0–$80 | Cash: $11–$360 What Is Intuniv? Intuniv is the brand name for guanfacine extended-release (ER), a once-daily non-stimulant prescription medication used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents ages 6 to 17. It was originally developed as an antihypertensive agent and belongs to the class of centrally acting alpha-2A adrenergic receptor agonists. Intuniv is available as extended-release tablets in four strengths: 1 mg, 2 mg, 3 mg, and 4 mg. Generic guanfacine ER is... ### Invega **Generic:** paliperidone Findability: 72/100 | Insurance: $0–$50 | Cash: $32–$684 What Is Invega? Invega is the brand name for paliperidone, an atypical (second-generation) antipsychotic manufactured by Janssen Pharmaceuticals (Johnson & Johnson). Paliperidone is the primary active metabolite of risperidone — it's the chemical form that risperidone converts to in the body. Invega delivers paliperidone directly using OROS extended-release technology, allowing once-daily dosing without the variability of hepatic metabolism. Invega was first FDA-approved in December 2006 for... ### Invokamet **Generic:** Invokamet Findability: 55/100 | Shortage: monitoring | Insurance: $50–$150 | Cash: $575–$800 What Is Invokamet? Invokamet is a prescription combination medication containing Canagliflozin (an SGLT2 inhibitor) and Metformin Hydrochloride (a biguanide). It is used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes when treatment with both Canagliflozin and Metformin is appropriate. The Canagliflozin component has also been shown to reduce the risk of major adverse cardiovascular events — including heart attack, stroke, and cardiovascular death —... ### Ipratropium **Generic:** Ipratropium Findability: 70/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $14–$530 What Is Ipratropium? Ipratropium (brand name Atrovent) is a short-acting anticholinergic bronchodilator used primarily to treat bronchospasm associated with COPD, including chronic bronchitis and emphysema. It's available as an inhaler, nebulizer solution, and nasal spray. The nasal spray formulations are used to relieve runny nose (rhinorrhea) caused by the common cold or seasonal allergic rhinitis. Ipratropium is also frequently used off-label alongside short-acting beta-agonists like... ### Iron Carbonyl **Generic:** carbonyl iron Findability: 75/100 | Insurance: $0–$15 | Cash: $3–$25 What Is Iron Carbonyl? Iron Carbonyl (carbonyl iron) is an over-the-counter iron replacement supplement used to treat and prevent iron deficiency and iron deficiency anemia (IDA). It is available under brand names including Feosol Natural Release, Icar, Ferra-Cap, Wee Care, and Vitron-C (combination with vitamin C), as well as generic carbonyl iron tablets and liquid suspensions. Unlike traditional ferrous iron salts (such as ferrous sulfate), Iron Carbonyl is composed of elemental iron —... ### Isentress **Generic:** Isentress Findability: 55/100 | Shortage: monitoring | Insurance: $50–$150 | Cash: $1,900–$2,500 What Is Isentress? Isentress (Raltegravir) is an antiretroviral medication manufactured by Merck & Co. that belongs to the Integrase Strand Transfer Inhibitor (INSTI) drug class. It is FDA-approved for the treatment of HIV-1 infection in adults and pediatric patients (from birth, weighing at least 2 kg) and is always used in combination with other antiretroviral agents. Isentress is also used off-label as part of post-exposure prophylaxis (PEP) regimens for HIV. ### Isibloom 28 Day **Generic:** desogestrel and ethinyl estradiol Findability: 65/100 | Insurance: $0–$20 | Cash: $12–$57 What Is Isibloom 28 Day? Isibloom 28 Day is a prescription monophasic combination oral contraceptive (COC) containing desogestrel (0.15 mg) and ethinyl estradiol (0.03 mg) per active tablet. It is a generic medication manufactured by Xiromed and is the therapeutic equivalent of the discontinued brand-name drug Desogen (originally Ortho-Cept). Each 28-day pack contains 21 active orange tablets and 7 inert green tablets. The active tablets contain the contraceptive hormones; the green tablets... ### Isosorbide **Generic:** isosorbide mononitrate Findability: 55/100 | Shortage: active | Insurance: $0–$25 | Cash: $8–$80 What Is Isosorbide? Isosorbide is a nitrate medication used to prevent chest pain (angina) caused by coronary artery disease. It comes in two main forms: isosorbide mononitrate (ISMN) and isosorbide dinitrate (ISDN). Isosorbide mononitrate is the more commonly prescribed form and is the active metabolite of isosorbide dinitrate. Brand names for isosorbide mononitrate included Imdur (extended-release), Monoket, and ISMO — all of which have been discontinued. Only generic isosorbide mononitrate... ### Isradipine **Generic:** isradipine Findability: 52/100 | Shortage: resolved | Insurance: $0–$40 | Cash: $188–$910 What Is Isradipine? Isradipine is a prescription calcium channel blocker (CCB) in the dihydropyridine subclass, approved by the FDA for the treatment of hypertension (high blood pressure). It was originally marketed under the brand names DynaCirc and DynaCirc CR, both of which have been permanently discontinued. As of 2026, only generic isradipine capsules — manufactured by Teva Pharmaceuticals — are available in the United States. Isradipine is prescribed for adults with hypertension, either... ### Istalol **Generic:** timolol maleate ophthalmic Findability: 68/100 | Insurance: $0–$30 | Cash: $35–$483 What Is Istalol? Istalol is the brand name for timolol maleate ophthalmic solution 0.5%, manufactured by Bausch + Lomb. It is a non-selective beta-adrenergic receptor blocker (beta-blocker) prescribed as a once-daily eye drop for the treatment of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. The FDA first approved the Istalol formulation on June 4, 2004. Istalol is unique among timolol formulations because its special formulation allows... ### Itch-X **Generic:** pramoxine hcl / benzyl alcohol Findability: 82/100 | Insurance: $0–$10 | Cash: $8–$15 What Is Itch-X? Itch-X is an over-the-counter topical anti-itch medication manufactured by B.F. Ascher & Company, Inc. It is available as a gel (1.25 oz tube) and a spray. The product contains two active ingredients: pramoxine hydrochloride 1% (a topical local anesthetic) and benzyl alcohol 10% (a topical analgesic), along with soothing aloe vera. Itch-X is used for temporary relief of pain and itching from insect bites, minor burns, sunburn, minor cuts and scrapes, hives, and rashes from... ### Ivabradine **Generic:** ivabradine Findability: 72/100 | Insurance: $0–$60 | Cash: $55–$900 What Is Ivabradine? Ivabradine (brand name: Corlanor, made by Amgen) is a prescription heart medication approved by the FDA on April 15, 2015. It is the first and only drug in its class in the United States — an HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that selectively slows heart rate through a unique mechanism not shared by any other cardiac drug. Ivabradine is FDA-approved to reduce the risk of hospitalization for worsening heart failure in adults with... ### Ivermectin **Generic:** ivermectin Findability: 65/100 | Insurance: $0–$30 | Cash: $28–$157 What Is Ivermectin? Ivermectin is a prescription antiparasitic medication belonging to the avermectin family of drugs. First discovered from a Japanese soil bacterium (Streptomyces avermitilis) in the late 1970s, it received FDA approval for human use in 1987. Its discovery earned William Campbell and Satoshi Ōmura the 2015 Nobel Prize in Physiology or Medicine. Ivermectin is on the World Health Organization's List of Essential Medicines and is one of the most widely used antiparasitic drugs... ### Jantoven **Generic:** warfarin sodium Findability: 90/100 | Insurance: $0–$10 | Cash: $4–$22 What Is Jantoven? Jantoven is the brand name for warfarin sodium tablets, manufactured by Upsher-Smith Laboratories and available in strengths from 1 mg to 10 mg. It belongs to the drug class known as vitamin K antagonists (VKA) or coumarins. Jantoven was first FDA-approved in 1954 and remains one of the most widely prescribed anticoagulants in the United States. Jantoven is prescribed to treat and prevent blood clots in conditions including deep vein thrombosis (DVT), pulmonary embolism... ### Januvia **Generic:** sitagliptin Findability: 72/100 | Insurance: $5–$150 | Cash: $285–$700 What Is Januvia? Januvia (sitagliptin) is a prescription oral medication used to improve blood sugar control in adults with type 2 diabetes mellitus. It was FDA-approved in October 2006 and is manufactured by Merck & Co., Inc. Januvia belongs to the dipeptidyl peptidase-4 (DPP-4) inhibitor class of diabetes medications, also known as gliptins. Januvia is taken once daily as an oral tablet and is used alongside diet and exercise. It is available in three strengths — 25 mg, 50 mg, and 100 mg —... ### Jasmiel 28 Day **Generic:** drospirenone and ethinyl estradiol Findability: 82/100 | Insurance: $0–$30 | Cash: $32–$148 What Is Jasmiel 28 Day? Jasmiel 28 Day is an AB-rated generic combination oral contraceptive manufactured by Afaxys Pharma, LLC. It is the generic equivalent of Yaz (brand name by Bayer) and contains drospirenone 3 mg and ethinyl estradiol 0.02 mg. Each 28-day blister pack contains 24 active light pink tablets and 4 green placebo tablets. Jasmiel 28 Day is FDA-approved for three indications: (1) contraception to prevent pregnancy in females of reproductive potential; (2) treatment of... ### Jatenzo **Generic:** testosterone undecanoate Findability: 72/100 | Insurance: $0–$393 | Cash: $1,013–$1,658 What Is Jatenzo? Jatenzo (testosterone undecanoate) is a brand-name oral testosterone capsule approved by the FDA in March 2019 for testosterone replacement therapy (TRT) in adult males. It was the first new oral testosterone product approved in the United States in more than 60 years. Jatenzo is manufactured by Tolmar, Inc. Jatenzo is indicated for adult males with hypogonadism — a condition where the body does not produce sufficient testosterone — caused by a structural or genetic... ### Jencycla 28 Day **Generic:** norethindrone Findability: 82/100 | Insurance: $0–$15 | Cash: $15–$115 What Is Jencycla 28 Day? Jencycla 28 Day is a progestin-only oral contraceptive (POP), commonly called the "mini-pill," manufactured by Lupin Pharmaceuticals, Inc. Each green tablet contains 0.35 mg of norethindrone — a synthetic progestin that is a close relative of the naturally occurring hormone progesterone. Unlike combination birth control pills, Jencycla contains no estrogen. All 28 tablets in each pack are active — there are no placebo or inactive pills. This continuous dosing schedule... ### Jornay PM **Generic:** Jornay Pm Findability: 55/100 | Shortage: monitoring | Insurance: $75–$150 | Cash: $340–$620 What Is Jornay PM and What Does It Do? Jornay PM (methylphenidate hydrochloride) is an FDA-approved extended-release capsule used to treat Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 and older. What makes Jornay PM unique among ADHD stimulants is its evening dosing — patients take it between 6:30 PM and 9:30 PM, and the medication's delayed-release technology ensures that therapeutic levels are reached by the following morning and sustained throughout the day. This is... ### Journavx **Generic:** Journavx Findability: 55/100 | Shortage: monitoring | Insurance: $30–$657 | Cash: $477–$657 What Is Journavx? Journavx (Suzetrigine) is a groundbreaking non-opioid pain medication approved by the FDA in January 2025 for the treatment of moderate to severe acute pain in adults. Developed by Vertex Pharmaceuticals, it is the first NaV1.8 sodium channel blocker approved for clinical use. Unlike opioids, Journavx does not carry a risk of addiction or dependence, making it a significant advancement in pain management. It does not have a boxed warning and is not a controlled substance. ### Jublia **Generic:** efinaconazole Findability: 72/100 | Insurance: $0–$65 | Cash: $75–$1,055 What Is Jublia? Jublia is the brand name for efinaconazole 10% topical solution, a prescription antifungal medication FDA-approved to treat onychomycosis (toenail fungus) caused by Trichophyton rubrum and Trichophyton mentagrophytes. It is manufactured by Ortho Dermatologics, a Bausch Health company. Jublia was first approved by the FDA in June 2014 for adults, and its approval was expanded in April 2020 to include patients as young as 6 years old. It is one of only three topical prescription... ### Juluca **Generic:** dolutegravir/rilpivirine Findability: 55/100 | Insurance: $0–$500 | Cash: $3,681–$5,100 What Is Juluca? Juluca is a prescription antiretroviral medication used to treat HIV-1 infection in adults. It contains two drugs — dolutegravir 50 mg (an integrase strand transfer inhibitor, or INSTI) and rilpivirine 25 mg (a non-nucleoside reverse transcriptase inhibitor, or NNRTI) — combined in a single pink, oval tablet taken once daily with a meal. First approved by the FDA on November 21, 2017, Juluca was the first complete two-drug, single-pill, once-daily HIV regimen in the United... ### K-Phos Neutral **Generic:** potassium phosphate / sodium phosphate Findability: 55/100 | Insurance: $10–$50 | Cash: $22–$90 What Is K-Phos Neutral? K-Phos Neutral is a prescription phosphate supplement manufactured by Beach Products, Inc. (Tampa, FL). Each film-coated tablet contains 852 mg dibasic sodium phosphate, 155 mg monobasic potassium phosphate, and 130 mg monobasic sodium phosphate — yielding 250 mg of elemental phosphorus (8 mmol), 298 mg of sodium (13.0 mEq), and 45 mg of potassium (1.1 mEq) per tablet. K-Phos Neutral is used to treat hypophosphatemia (low phosphate levels in the blood) and to prevent... ### Kariva 28 Day **Generic:** desogestrel/ethinyl estradiol Findability: 78/100 | Insurance: $0–$15 | Cash: $10–$150 What Is Kariva 28 Day? Kariva 28 Day is a prescription biphasic combination oral contraceptive manufactured by Teva Pharmaceuticals. It contains two synthetic hormones — desogestrel (a third-generation progestin) and ethinyl estradiol (a synthetic estrogen) — and is FDA-approved for the prevention of pregnancy. Kariva is a generic equivalent of the discontinued brand-name pill Mircette. The 28-day pack uses a biphasic design: days 1-21 contain 0.15 mg desogestrel and 0.02 mg ethinyl... ### Kelnor 1/35 28 Day **Generic:** ethynodiol diacetate and ethinyl estradiol Findability: 78/100 | Insurance: $0–$30 | Cash: $14–$68 What Is Kelnor 1/35 28 Day? Kelnor 1/35 28 Day is a combination oral contraceptive manufactured by Teva Pharmaceuticals USA. Each active tablet contains 1 mg of ethynodiol diacetate (a progestin) and 35 mcg of ethinyl estradiol (an estrogen). The 28-tablet blister pack contains 21 active light yellow tablets followed by 7 white placebo tablets. Kelnor 1/35 is the generic successor to the discontinued brand Demulen 1/35. It is FDA-approved for the prevention of pregnancy and is equivalent in... ### Kenalog **Generic:** triamcinolone acetonide Findability: 35/100 | Shortage: active | Insurance: $0–$30 | Cash: $11–$80 What Is Kenalog? Kenalog is the brand name for triamcinolone acetonide, a synthetic glucocorticoid (corticosteroid) manufactured by Bristol-Myers Squibb. FDA-approved since 1965, it is one of the most widely used injectable corticosteroids in the United States. Kenalog is available in three injectable strengths — Kenalog-10 (10 mg/mL), Kenalog-40 (40 mg/mL), and Kenalog-80 (80 mg/mL) — as well as topical creams, ointments, and dental paste. Kenalog is used to treat a broad range of... ### Keppra **Generic:** levetiracetam Findability: 78/100 | Insurance: $0–$30 | Cash: $6–$153 What Is Keppra? Keppra is the brand name for levetiracetam, an anti-seizure (antiepileptic) medication used to treat epilepsy in adults and children. It belongs to the pyrrolidine anticonvulsant class and is chemically unrelated to all other anti-seizure medications. Levetiracetam was first FDA-approved in 1999, and a generic version has been available in the United States since 2008. Keppra is FDA-approved for three seizure types: partial-onset (focal) seizures in patients 1 month and older;... ### Kerendia **Generic:** Kerendia Findability: 65/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $670–$950 What Is Kerendia? Kerendia (Finerenone) is a non-steroidal mineralocorticoid receptor antagonist (MRA) manufactured by Bayer Healthcare. It is FDA-approved to reduce the risk of kidney function decline, kidney failure, cardiovascular death, non-fatal heart attacks, and hospitalization for heart failure in adults with chronic kidney disease (CKD) associated with type 2 diabetes. It is also approved to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with... ### Ketoconazole **Generic:** ketoconazole Findability: 82/100 | Insurance: $0–$20 | Cash: $23–$101 What Is Ketoconazole? Ketoconazole is a broad-spectrum azole antifungal medication that has been used clinically since the early 1980s. It is available in multiple forms: oral tablets (200 mg) for serious systemic fungal infections, and topical formulations — including 2% cream, 2% shampoo, 2% foam (Extina), and 2% gel (Xolegel/Ketodan) — for skin and scalp conditions. An over-the-counter 1% shampoo (Nizoral A-D) is also available without a prescription for dandruff control. Topical... ### Ketorolac **Generic:** Ketorolac Findability: 72/100 | Insurance: $0–$15 | Cash: $10–$25 What Is Ketorolac? Ketorolac (brand names Toradol, Sprix, Acular) is a powerful nonsteroidal anti-inflammatory drug (NSAID) used for the short-term management of moderately severe acute pain that requires opioid-level analgesia. It is available as oral tablets, injectable solution, nasal spray, and ophthalmic drops. Ketorolac is unique among NSAIDs because of its strong analgesic (pain-relieving) potency — it is often used in emergency departments and post-surgical settings as a non-opioid... ### Kevzara **Generic:** sarilumab Findability: 55/100 | Insurance: $0–$400 | Cash: $4,774–$5,555 What Is Kevzara? Kevzara (sarilumab) is a prescription biologic medication developed by Sanofi and Regeneron Pharmaceuticals. It is classified as an interleukin-6 (IL-6) receptor antagonist—a type of monoclonal antibody that blocks the IL-6 receptor to reduce inflammation in autoimmune conditions. Kevzara is a fully human IgG1 monoclonal antibody with an approximate molecular weight of 150 kDa, manufactured using recombinant DNA technology. Kevzara is FDA-approved for three conditions:... ### Klisyri **Generic:** tirbanibulin Findability: 55/100 | Insurance: $25–$100 | Cash: $95–$1,967 What Is Klisyri? Klisyri is the brand name for tirbanibulin 1% ointment, a prescription topical medication approved by the FDA on December 14, 2020. It is manufactured by Almirall, LLC (Malvern, PA) and is indicated for the topical field treatment of actinic keratosis (AK) on the face or scalp in adults. Actinic keratosis is a precancerous skin condition caused by chronic UV radiation exposure that affects an estimated 40 million Americans annually. Klisyri is classified as a first-in-class... ### Klonopin **Generic:** Klonopin Findability: 45/100 | Shortage: active | Insurance: $0–$15 | Cash: $8–$300 What Is Klonopin? Klonopin is the brand name for Clonazepam, a benzodiazepine anticonvulsant manufactured by Genentech (Roche). It is FDA-approved to treat seizure disorders (including Lennox-Gastaut syndrome, akinetic seizures, and myoclonic seizures) and panic disorder with or without agoraphobia. It is also sometimes prescribed off-label for generalized anxiety disorder, insomnia, restless legs syndrome, and essential tremor. ### Konvomep **Generic:** omeprazole and sodium bicarbonate Findability: 45/100 | Insurance: $5–$150 | Cash: $194–$272 What Is Konvomep? Konvomep is the brand name for omeprazole and sodium bicarbonate for oral suspension, manufactured by Azurity Pharmaceuticals. It was FDA-approved on August 30, 2022, and became commercially available in early 2023. Konvomep is a prescription liquid medication that combines omeprazole — a proton pump inhibitor (PPI) — with sodium bicarbonate to create a strawberry-flavored oral suspension. Konvomep is dispensed as a two-bottle kit: one containing omeprazole powder and one... ### Kristalose **Generic:** lactulose Findability: 55/100 | Insurance: $0–$50 | Cash: $108–$385 What Is Kristalose? Kristalose is the brand name for lactulose powder for oral solution, a prescription osmotic laxative manufactured by Cumberland Pharmaceuticals Inc. in Nashville, Tennessee. It is FDA-approved for the treatment of chronic constipation in adults. Unlike generic lactulose, which is available as a pre-mixed liquid syrup, Kristalose comes as crystallized powder in single-dose packets — either 10g or 20g per packet — that you dissolve in water before drinking. This format... ### Kyleena **Generic:** levonorgestrel-releasing intrauterine system Findability: 80/100 | Insurance: $0–$50 | Cash: $1,272–$1,656 What Is Kyleena? Kyleena (levonorgestrel-releasing intrauterine system, 19.5 mg) is a small, flexible, T-shaped hormonal intrauterine device (IUD) manufactured by Bayer and FDA-approved since September 2016. It prevents pregnancy for up to 5 years by slowly releasing levonorgestrel — a synthetic progestin hormone — directly into the uterus. Kyleena is available by prescription only and must be inserted by a trained healthcare provider during an in-office procedure. Kyleena is the smallest and... ### Lacosamide **Generic:** Lacosamide Findability: 65/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $24–$45 What Is Lacosamide and What Does It Do? Lacosamide (brand name Vimpat) is an antiepileptic drug used to treat partial-onset (focal) seizures in patients as young as 1 month old. It is approved as both an add-on therapy and as a standalone treatment for focal seizures in patients 4 years and older. Lacosamide is also approved as adjunctive therapy for primary generalized tonic-clonic seizures in patients 4 years of age and older. It belongs to the functionalized amino acid class of... ### Lacrisert **Generic:** hydroxypropyl cellulose ophthalmic insert Findability: 45/100 | Shortage: resolved | Insurance: $0–$150 | Cash: $578–$691 What Is Lacrisert? Lacrisert is a prescription ophthalmic insert containing 5 mg of hydroxypropyl cellulose (HPC), a water-soluble polymer. It is a sterile, translucent, rod-shaped insert designed to be placed once daily into the inferior cul-de-sac of the eye — the pocket between the lower eyelid and the eyeball. The insert slowly dissolves throughout the day, providing sustained lubrication to the ocular surface. Lacrisert is manufactured by Renaissance Lakewood, LLC and distributed by... ### Lactulose **Generic:** lactulose Findability: 88/100 | Insurance: $0–$15 | Cash: $4–$65 What Is Lactulose? Lactulose is a synthetic sugar — a disaccharide made from galactose and fructose — used as a prescription laxative in the United States. It has been used medically since 1966 and received FDA approval in 1977. With over 900,000 prescriptions filled in 2023, it is one of the most commonly prescribed laxative medications in the country. Lactulose is FDA-approved for two primary indications: chronic constipation (Kristalose powder form) and prevention and treatment of... ### Lagevrio **Generic:** molnupiravir Findability: 45/100 | Shortage: active | Insurance: $10–$50 | Cash: $993–$1,170 What Is Lagevrio (Molnupiravir)? Lagevrio is the brand name for molnupiravir, an oral antiviral medication made by Merck Sharp & Dohme LLC (in collaboration with Ridgeback Biotherapeutics). It is authorized under FDA Emergency Use Authorization (EUA) for the treatment of mild-to-moderate COVID-19 in high-risk adults. Lagevrio is taken as four 200 mg capsules (800 mg total) orally twice daily for 5 days — a total of 40 capsules. Lagevrio is prescribed for adults who test positive for COVID-19,... ### Lamictal XR **Generic:** lamotrigine extended-release Findability: 62/100 | Insurance: $0–$30 | Cash: $16–$1,225 What Is Lamictal XR? Lamictal XR is the brand name for lamotrigine extended-release tablets, manufactured by GlaxoSmithKline (GSK). It is a once-daily anticonvulsant (anti-seizure medication) and mood stabilizer approved by the FDA for patients aged 13 years and older. The extended-release formulation allows once-daily dosing, compared to the twice-daily dosing required with immediate-release lamotrigine (Lamictal). Lamictal XR is FDA-approved for adjunctive therapy for partial-onset... ### Lamotrigine **Generic:** lamotrigine Findability: 82/100 | Insurance: $0–$30 | Cash: $4–$47 What Is Lamotrigine? Lamotrigine (brand name Lamictal, also sold as Subvenite) is an anticonvulsant (anti-seizure) medication that also serves as a mood stabilizer for bipolar disorder. First approved by the FDA in 1994, it is on the World Health Organization's List of Essential Medicines and is one of the most widely prescribed medications in the United States — ranking as the most commonly prescribed mood stabilizer and the 59th most prescribed drug overall in 2023, with more than 10 million... ### Lanabiotic **Generic:** bacitracin / neomycin / polymyxin b / pramoxine Findability: 92/100 | Insurance: $0 | Cash: $5–$15 What Is Lanabiotic? Lanabiotic is a brand-name over-the-counter (OTC) topical ointment that combines two broad-spectrum antibiotics with a topical local anesthetic. It is designed to prevent infection and relieve pain in minor cuts, scrapes, and burns. Lanabiotic does not require a prescription and is available at pharmacies, grocery stores, and online retailers. Its three active ingredients are Neomycin Sulfate (3.5 mg per gram), an aminoglycoside antibiotic; Polymyxin B Sulfate (10,000... ### Lantiseptic **Generic:** lanolin Findability: 60/100 | Insurance: $0 | Cash: $8–$25 What Is Lantiseptic? Lantiseptic is a brand-name line of over-the-counter (OTC) topical skin protectants manufactured by DermaRite Industries LLC. The flagship product—Lantiseptic Original Skin Protectant (also marketed as Lantiseptic Moisture Shield)—contains 50% Lanolin USP as its active ingredient, combined with petrolatum, beeswax, and mineral oil. The product line includes several formulations designed for different skin care needs: the Original 50% lanolin barrier ointment, Lantiseptic... ### Larin 24 Fe 1/20 **Generic:** norethindrone acetate ethinyl estradiol ferrous fumarate Findability: 88/100 | Insurance: $0–$30 | Cash: $11–$90 What Is Larin 24 Fe 1/20? Larin 24 Fe 1/20 is a combination oral contraceptive (birth control pill) manufactured by Northstar Rx LLC. It contains two synthetic hormones: norethindrone acetate 1 mg (a progestin) and ethinyl estradiol 20 mcg (an estrogen) in the active tablets, plus 4 placebo tablets containing 75 mg ferrous fumarate (iron) per 28-tablet blister pack. The "24 Fe" designation refers to the 24-day active hormone schedule (compared to older 21-day regimens), which shortens the... ### Lasix **Generic:** furosemide Findability: 75/100 | Shortage: active | Insurance: $0–$15 | Cash: $2–$43 What Is Lasix (Furosemide)? Lasix is the brand name for furosemide, a powerful loop diuretic (water pill) that has been a cornerstone of cardiovascular medicine since FDA approval in the 1960s. It is prescribed to millions of Americans each year to treat edema (fluid retention) and high blood pressure. Generic furosemide is available and bioequivalent to brand-name Lasix. Furosemide is FDA-approved for treating edema caused by congestive heart failure, liver disease (cirrhosis), and kidney... ### Latanoprost **Generic:** latanoprost Findability: 82/100 | Insurance: $0–$30 | Cash: $9–$82 What Is Latanoprost? Latanoprost is a prescription ophthalmic eye drop medication used to treat open-angle glaucoma and ocular hypertension (elevated intraocular pressure). It is sold under the brand name Xalatan and is widely available as a generic medication. In 2023, latanoprost was the 67th most commonly prescribed medication in the United States, with over 9 million prescriptions filled. Latanoprost belongs to the prostaglandin analogue class of medications. It was FDA-approved in 1996... ### Latisse **Generic:** Latisse Findability: 72/100 | Insurance: $30–$75 | Cash: $35–$280 What Is Latisse? Latisse (bimatoprost ophthalmic solution 0.03%) is an FDA-approved prescription treatment for hypotrichosis of the eyelashes — a condition where eyelashes are inadequate or insufficient. It is manufactured by AbbVie (formerly Allergan) and works by increasing eyelash growth, making lashes longer, thicker, and darker. Latisse is the only FDA-approved prescription treatment specifically for eyelash growth. It is a prostaglandin analog that extends the active growth phase of the... ### Layolis Fe 28 **Generic:** norethindrone and ethinyl estradiol Findability: 62/100 | Insurance: $0–$25 | Cash: $76–$150 What Is Layolis Fe 28? Layolis Fe 28 is a prescription combination oral contraceptive (birth control pill) containing two synthetic hormones: norethindrone 0.8 mg (a progestin) and ethinyl estradiol 0.025 mg (25 mcg) (a synthetic estrogen). It also includes ferrous fumarate 75 mg (iron) in the 4 placebo tablets taken during the fourth week of each pack. Layolis Fe 28 is a generic version of Generess Fe, manufactured by Actavis Pharma. What makes it unique among oral contraceptives is its... ### Lentocilin **Generic:** penicillin g benzathine Findability: 28/100 | Shortage: active | Insurance: $0–$50 | Cash: $15–$500+ What Is Lentocilin? Lentocilin is a brand name for benzathine benzylpenicillin (penicillin G benzathine), a long-acting injectable antibiotic belonging to the natural penicillin class. It is manufactured in Portugal by Laboratórios Atral S.A. and is currently imported into the United States under FDA enforcement discretion to address the severe shortage of Bicillin L-A — the domestically manufactured equivalent made by Pfizer. Lentocilin is the gold standard treatment for syphilis at all... ### Leqvio **Generic:** inclisiran Findability: 72/100 | Insurance: $0–$10 | Cash: $3,652–$3,731 What Is Leqvio? Leqvio (inclisiran) is a first-in-class small interfering RNA (siRNA) medication manufactured by Novartis Pharmaceuticals Corporation. It was FDA-approved on December 22, 2021, and is used to lower LDL cholesterol ("bad" cholesterol) in adults with primary hyperlipidemia, including heterozygous familial hypercholesterolemia (HeFH) and atherosclerotic cardiovascular disease (ASCVD). Leqvio is given as a subcutaneous (under the skin) injection of 284 mg, administered by a... ### Letrozole **Generic:** letrozole Findability: 82/100 | Insurance: $0–$30 | Cash: $12–$341 What Is Letrozole? Letrozole is a prescription oral medication belonging to the class of drugs called nonsteroidal aromatase inhibitors (AIs). It is sold under the brand name Femara (manufactured by Novartis), and is widely available as a generic from multiple manufacturers. Letrozole comes as a 2.5 mg tablet taken once daily. Letrozole is FDA-approved for treating hormone receptor-positive breast cancer in postmenopausal women — including adjuvant therapy after surgery, extended adjuvant... ### Leucovorin **Generic:** Leucovorin Findability: 35/100 | Shortage: active | Insurance: $5–$50 | Cash: $24–$500+ What Is Leucovorin? Leucovorin (also known as Leucovorin Calcium or Folinic Acid) is a reduced form of folic acid used in several critical medical situations. It is most commonly used as a "rescue" agent after high-dose Methotrexate therapy to protect healthy cells from Methotrexate toxicity. It is also used alongside 5-Fluorouracil (5-FU) in the treatment of advanced colorectal cancer, where it enhances the cancer-fighting effects of 5-FU. Additionally, Leucovorin can treat megaloblastic... ### Levalbuterol **Generic:** levalbuterol Findability: 72/100 | Insurance: $5–$45 | Cash: $25–$120 What Is Levalbuterol? Levalbuterol is a prescription bronchodilator used to treat and prevent bronchospasm in patients with asthma, COPD, and other reversible obstructive airway diseases. It is available under the brand names Xopenex (nebulizer solution) and Xopenex HFA (metered-dose inhaler), with generic versions of both forms available. It is classified as a short-acting beta2-adrenergic agonist (SABA) and is commonly called a rescue inhaler or quick-relief medication. Levalbuterol is the... ### Levamlodipine **Generic:** levamlodipine Findability: 62/100 | Insurance: $0–$50 | Cash: $70–$427 What Is Levamlodipine? Levamlodipine (brand name Conjupri) is a prescription antihypertensive medication approved by the FDA in December 2019. It belongs to the dihydropyridine calcium channel blocker (CCB) class and is indicated for the treatment of hypertension (high blood pressure) in adults and pediatric patients 6 years and older. Levamlodipine is the purified (S)-enantiomer of amlodipine—the pharmacologically active half of the widely used blood pressure drug amlodipine (Norvasc).... ### Levemir **Generic:** Levemir Findability: 3/100 | Shortage: active | Insurance: $25–$75 | Cash: $350–$500 What Is Levemir? Levemir (Insulin Detemir) is a long-acting insulin analogue manufactured by Novo Nordisk. It is FDA-approved for the treatment of type 1 diabetes in adults and children aged 2 years and older, and type 2 diabetes in adults. Levemir provides a steady level of background (basal) insulin for up to 24 hours and is typically injected once or twice daily. First approved in the US in June 2005, Levemir was once one of the most commonly prescribed insulins, with over 3 million... ### Levetiracetam **Generic:** levetiracetam Findability: 72/100 | Insurance: $0–$30 | Cash: $6–$153 What Is Levetiracetam? Levetiracetam is a prescription antiepileptic drug (AED) used to treat epilepsy in adults and children. Sold under brand names including Keppra, Keppra XR, Spritam, and Roweepra, it is one of the most commonly prescribed seizure medications in the United States—with more than 6 million prescriptions dispensed annually. Generic levetiracetam has been available since 2008, making it substantially more affordable than the original brand. The FDA first approved... ### Levofloxacin **Generic:** levofloxacin Findability: 74/100 | Shortage: active | Insurance: $0–$30 | Cash: $15–$80 What Is Levofloxacin? Levofloxacin is a broad-spectrum antibiotic belonging to the fluoroquinolone drug class. Originally sold under the brand name Levaquin (now discontinued), it is available only as a generic in the United States. It received FDA approval in 1996 and is included on the World Health Organization's List of Essential Medicines. Levofloxacin is FDA-approved to treat a wide range of bacterial infections including community-acquired pneumonia, hospital-acquired pneumonia, urinary... ### Levomilnacipran XR **Generic:** Levomilnacipran XR Findability: 60/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $150–$520 What Is Levomilnacipran XR? Levomilnacipran XR (brand name Fetzima) is an extended-release antidepressant medication approved by the FDA for treating Major Depressive Disorder (MDD) in adults. It belongs to a class of medications called serotonin-norepinephrine reuptake inhibitors (SNRIs). Unlike other SNRIs, levomilnacipran has a unique profile with approximately 15-fold higher selectivity for blocking norepinephrine reuptake compared to serotonin, making it particularly effective for... ### Levothyroxine **Generic:** levothyroxine Findability: 75/100 | Insurance: $0–$30 | Cash: $4–$80 What Is Levothyroxine? Levothyroxine is a synthetic version of thyroxine (T4), the primary hormone produced by the thyroid gland. It is one of the most prescribed medications in the United States, used by an estimated 23 million Americans to treat hypothyroidism — a condition where the thyroid gland fails to produce enough thyroid hormone. Brand names include Synthroid (AbbVie), Levoxyl (Pfizer), Tirosint (gel capsule), Tirosint-Sol, Thyquidity (oral liquids), Unithroid, Euthyrox, Ermeza, and... ### Lexette **Generic:** Lexette Findability: 55/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $25–$1,000 What Is Lexette? Lexette is a brand-name prescription topical foam containing Halobetasol Propionate 0.05%, a super high potency (Class I) topical corticosteroid manufactured by Mayne Pharma. It is FDA-approved for the treatment of plaque psoriasis in patients 12 years of age and older. Lexette works by reducing inflammation, redness, itching, and scaling on the skin. It is applied as a thin layer to affected areas twice daily for up to 2 weeks, with a maximum of 50 grams per week. ### Lialda **Generic:** mesalamine Findability: 80/100 | Insurance: $0–$50 | Cash: $45–$1,469 What Is Lialda? Lialda is a brand-name prescription medication containing mesalamine (also called 5-aminosalicylic acid, or 5-ASA) in a 1.2 g delayed-release tablet formulation. It belongs to a class of drugs called aminosalicylates, which are anti-inflammatory agents that act locally in the colon. FDA-approved on January 16, 2007, Lialda was the first once-daily oral mesalamine product in the United States. It uses proprietary MMX (Multi-Matrix System) Technology to deliver mesalamine... ### Librax **Generic:** chlordiazepoxide/clidinium Findability: 72/100 | Insurance: $0–$30 | Cash: $20–$1,042 What Is Librax? Librax is a prescription combination capsule containing chlordiazepoxide 5 mg and clidinium bromide 2.5 mg. FDA-approved since 1966, it is used to treat gastrointestinal conditions including irritable bowel syndrome (IBS), peptic ulcer disease, and acute enterocolitis. It is always prescribed as adjunctive therapy alongside other treatments. Brand Librax is manufactured by Bausch Health US, LLC. Generic versions (chlordiazepoxide/clidinium) are available from multiple... ### Lidocaine **Generic:** lidocaine Findability: 40/100 | Shortage: active | Insurance: $0–$60 | Cash: $10–$85 What Is Lidocaine? Lidocaine is an amide-type local anesthetic and Class Ib antiarrhythmic drug. First synthesized in 1943 and FDA-approved in 1948, it has become one of the most widely used medications in medicine. Its combination of rapid onset, favorable safety profile, and versatility across dozens of formulations makes it indispensable across virtually every medical specialty. Brand names include Xylocaine (injectable), Lidoderm (5% transdermal patch), ZTLido (1.8% hydrogel patch),... ### Lidopro Patch **Generic:** Lidopro Patch Findability: 35/100 | Shortage: active | Insurance: $30–$75 | Cash: $150–$350 What Is Lidopro Patch? Lidopro Patch is a topical analgesic combination patch manufactured by Terrain Pharmaceuticals (TerrainRx). It contains three active ingredients — Lidocaine (a local anesthetic), Menthol (a counterirritant), and Methyl Salicylate (a topical NSAID) — delivered through patented hydrogel transdermal technology. It is used for the temporary relief of minor aches and pains associated with arthritis, back pain, muscle strains and sprains, joint pain, shoulder pain, and knee... ### Likmez **Generic:** metronidazole Findability: 45/100 | Insurance: $0–$80 | Cash: $207–$246 What Is Likmez? Likmez is the brand name for metronidazole oral suspension 500 mg/5 mL — the first and only FDA-approved ready-to-use liquid formulation of metronidazole in the United States. It was approved on September 25, 2023, manufactured by Saptalis Pharmaceuticals, and marketed by Kesin Pharma. The suspension has a strawberry-peppermint flavor and does not require refrigeration. Likmez was specifically developed to address a real clinical gap: patients who cannot take conventional... ### Linezolid **Generic:** linezolid Findability: 45/100 | Shortage: active | Insurance: $30–$100 | Cash: $35–$1,927 What Is Linezolid? Linezolid is a synthetic antibiotic in the oxazolidinone class, best known by its brand name Zyvox. It was FDA-approved on April 18, 2000 — the first member of a new antibiotic class developed in decades — and remains one of the most important drugs for treating infections caused by drug-resistant gram-positive bacteria. Linezolid is FDA-approved to treat hospital-acquired and community-acquired pneumonia, complicated and uncomplicated skin and skin structure infections,... ### Linzess **Generic:** linaclotide Findability: 80/100 | Insurance: $30–$75 | Cash: $252–$736 What Is Linzess? Linzess is the brand name for linaclotide, a prescription oral capsule used to treat certain types of chronic constipation and bowel disorders. It belongs to a drug class called guanylate cyclase-C (GC-C) agonists and was FDA-approved in August 2012. Linzess is manufactured by AbbVie in partnership with Ironwood Pharmaceuticals and is available in three strengths: 72 mcg, 145 mcg, and 290 mcg. Linzess is FDA-approved for three conditions: irritable bowel syndrome with... ### Liothyronine **Generic:** liothyronine Findability: 65/100 | Insurance: $0–$30 | Cash: $25–$85 What Is Liothyronine? Liothyronine is a synthetic form of triiodothyronine (T3), one of the two main hormones produced by the thyroid gland. It is sold under the brand name Cytomel (oral tablets) and Triostat (IV injection for hospital use). Liothyronine has been FDA-approved since 1956 and is available as a generic medication. Unlike levothyroxine (T4), which must be converted to active T3 in the body, liothyronine is already in the biologically active form. It acts faster than levothyroxine... ### Lipitor **Generic:** atorvastatin Findability: 95/100 | Insurance: $0-$10 | Cash: $4-$97 What Is Lipitor? Lipitor is the brand name for atorvastatin calcium, a prescription medication classified as an HMG-CoA reductase inhibitor — commonly known as a statin. It was developed by Pfizer and first approved by the FDA in 1996. Lipitor was once the world's best-selling drug, and today its generic equivalent, atorvastatin, remains one of the most widely prescribed medications in the United States. Atorvastatin is used to lower LDL ("bad") cholesterol and triglycerides, raise HDL... ### Liraglutide **Generic:** Liraglutide Findability: 40/100 | Shortage: active | Insurance: $20–$150 | Cash: $230–$1,400 What Is Liraglutide? Liraglutide is a GLP-1 receptor agonist (incretin mimetic) used to treat type 2 diabetes and chronic weight management. It is marketed under two brand names: Victoza (for type 2 diabetes in adults and children aged 10+) and Saxenda (for weight management in adults with BMI ≥30, or BMI ≥27 with a weight-related comorbidity, and in adolescents aged 12+). Victoza is also approved to reduce major adverse cardiovascular events in adults with type 2 diabetes and established... ### Lisdexamfetamine **Generic:** Lisdexamfetamine Findability: 45/100 | Shortage: active | Insurance: $20–$75 | Cash: $60–$360 What Is Lisdexamfetamine? Lisdexamfetamine (brand name Vyvanse) is a central nervous system (CNS) stimulant and amphetamine prodrug approved by the FDA for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 and older, and moderate to severe Binge Eating Disorder (BED) in adults. Unlike traditional amphetamines, Lisdexamfetamine is a prodrug — meaning it is inactive until your body converts it into its active form, dextroamphetamine, after ingestion. This... ### Lithium Carbonate **Generic:** lithium carbonate Findability: 82/100 | Insurance: $0–$30 | Cash: $7–$55 What Is Lithium Carbonate? Lithium Carbonate is a mood-stabilizing medication used primarily to treat and prevent manic episodes in people with Bipolar I Disorder. It is one of the oldest and most studied psychiatric medications in existence, having received FDA approval in 1970 after decades of clinical use. It is also listed on the World Health Organization's List of Essential Medicines. Lithium Carbonate is FDA-approved for the treatment of acute manic and mixed episodes of Bipolar I... ### Lo Zumandimine 28 Day **Generic:** drospirenone and ethinyl estradiol Findability: 80/100 | Insurance: $0–$30 | Cash: $30–$156 What Is Lo Zumandimine 28 Day? Lo Zumandimine 28 Day is a combination oral contraceptive (birth control pill) manufactured by Aurobindo Pharma Limited. It contains two synthetic hormones: drospirenone 3 mg (a progestin) and ethinyl estradiol 0.02 mg (an estrogen). Lo Zumandimine is an AB-rated generic equivalent of Yaz — one of the most prescribed birth control pills in the United States. Each 28-tablet blister pack contains 24 active (light pink) hormone tablets and 4 inert (green) reminder... ### Lofexidine **Generic:** lofexidine Findability: 55/100 | Insurance: $20–$150 | Cash: $383–$2,333 What Is Lofexidine? Lofexidine (brand name Lucemyra) is a prescription medication approved by the U.S. Food and Drug Administration in May 2018 to help manage opioid withdrawal symptoms in adults. It was the first — and remains the only — non-opioid medication specifically FDA-approved for this indication, representing a significant milestone in addiction medicine. Lofexidine belongs to a class of drugs called alpha-2 adrenergic agonists. It is a structural analogue of clonidine but with... ### Lomaira **Generic:** phentermine hydrochloride Findability: 45/100 | Insurance: $5–$50 | Cash: $17–$70 What Is Lomaira? Lomaira (phentermine hydrochloride USP 8 mg, CIV) is a brand-name prescription weight-loss tablet manufactured by KVK Tech, Inc. FDA-approved on September 13, 2016, it is classified as a sympathomimetic amine anorectic — a stimulant-class appetite suppressant with over 65 years of real-world experience in weight management. Lomaira is unique among phentermine products: it contains the lowest FDA-approved dose (8 mg) and is designed to be taken up to three times daily, 30... ### Lomustine **Generic:** lomustine Findability: 45/100 | Shortage: resolved | Insurance: $0–$500+ | Cash: $600–$2,950 What Is Lomustine? Lomustine is an oral chemotherapy drug in the nitrosourea alkylating agent class. It is sold under the brand name Gleostine (and formerly as CeeNU, which was discontinued in 2013 by Bristol-Myers Squibb). In oncology literature, it is often referred to as CCNU. The FDA first approved lomustine in 1977, and it remains a clinically important treatment for brain tumors and Hodgkin's lymphoma nearly 50 years later. Lomustine is FDA-approved for primary and metastatic brain... ### Lorazepam **Generic:** Lorazepam Findability: 70/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $3–$30 What Is Lorazepam? Lorazepam (brand name Ativan) is a benzodiazepine medication used to treat anxiety disorders, short-term anxiety relief, insomnia related to anxiety, and status epilepticus (seizures). It is also used for preoperative sedation. Lorazepam works quickly and is considered an intermediate-acting benzodiazepine, making it useful for both acute anxiety and short-term management of anxiety symptoms. Off-label, Lorazepam is also prescribed for alcohol withdrawal,... ### Loryna 28 Day **Generic:** drospirenone / ethinyl estradiol Findability: 55/100 | Insurance: $0–$15 | Cash: $75–$100 What Is Loryna 28 Day? Loryna 28 Day is a combination oral contraceptive (birth control pill) containing drospirenone 3 mg and ethinyl estradiol 0.02 mg (20 mcg). It is a branded generic of the original Yaz formulation, manufactured by Laboratorios Leon Farma in Spain and distributed in the U.S. by Xiromed, LLC. Each 28-day blister pack contains 24 active peach tablets with both hormones and 4 white inert (placebo) tablets. Loryna is FDA-approved for three indications: (1) contraception, (2)... ### Losartan **Generic:** losartan potassium Findability: 88/100 | Insurance: $0–$15 | Cash: $10–$55 What Is Losartan? Losartan (brand name Cozaar) is an angiotensin II receptor blocker (ARB) approved by the FDA for treating high blood pressure (hypertension), diabetic nephropathy, and reducing stroke risk in patients with hypertension and left ventricular hypertrophy. It is one of the most prescribed medications in the United States — the 8th most prescribed drug in 2023 with over 56 million prescriptions. First approved by the FDA in 1995, losartan was the first ARB to reach clinical use... ### Lotemax **Generic:** loteprednol etabonate Findability: 72/100 | Insurance: $25–$100 | Cash: $50–$441 What Is Lotemax? Lotemax is the brand name for loteprednol etabonate, a prescription ophthalmic corticosteroid (steroid eye drop) manufactured by Bausch + Lomb. First approved by the FDA in 1998, Lotemax is used to treat inflammation and pain following eye surgery, as well as a range of steroid-responsive inflammatory eye conditions including allergic conjunctivitis, ocular rosacea, iritis, and herpes zoster keratitis. Lotemax is commonly called a "soft steroid" because it is engineered to... ### Loteprednol Etabonate **Generic:** loteprednol etabonate Findability: 78/100 | Insurance: $0–$80 | Cash: $49–$441 What Is Loteprednol Etabonate? Loteprednol Etabonate is a prescription ophthalmic corticosteroid (steroid eye drop) used to reduce inflammation in the eye. It is sold under several brand names, including Lotemax, Lotemax SM, Alrex, Eysuvis, and Inveltys. The drug was FDA-approved in 1998 and is manufactured primarily by Bausch + Lomb. Loteprednol Etabonate is used to treat post-operative eye inflammation after cataract surgery and other eye procedures, seasonal allergic conjunctivitis (Alrex... ### Lovenox **Generic:** Lovenox Findability: 65/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $25–$600+ What Is Lovenox? Lovenox is the brand name for Enoxaparin Sodium, a low molecular weight heparin (LMWH) anticoagulant manufactured by Sanofi-Aventis. It is an injectable blood thinner used to prevent and treat dangerous blood clots. Lovenox is FDA-approved for: Prevention of deep vein thrombosis (DVT) after hip or knee replacement surgery Prevention of DVT after abdominal surgery in at-risk patients Treatment of acute DVT with or without pulmonary embolism (PE) Prevention of blood clot... ### Low-Ogestrel 28 Day **Generic:** norgestrel / ethinyl estradiol Findability: 82/100 | Insurance: $0–$15 | Cash: $43–$74 What Is Low-Ogestrel 28 Day? Low-Ogestrel 28 Day is a combination oral contraceptive (birth control pill) containing two synthetic hormones: norgestrel (0.3 mg) and ethinyl estradiol (0.03 mg). It is taken daily to prevent pregnancy by suppressing ovulation, thickening cervical mucus, and thinning the uterine lining. Each 28-day pack contains 21 white active hormone tablets and 7 peach placebo tablets. It is a monophasic pill — every active tablet delivers the same dose of hormones.... ### Lubiprostone **Generic:** lubiprostone Findability: 62/100 | Insurance: $0–$60 | Cash: $33–$530 What Is Lubiprostone? Lubiprostone, sold under the brand name Amitiza, is a prescription medication used to treat chronic constipation and related conditions in adults. It belongs to a drug class called chloride channel activators — a targeted approach to constipation that works differently from over-the-counter laxatives. The FDA first approved Lubiprostone in January 2006 for chronic idiopathic constipation (CIC). It was subsequently approved in 2008 for irritable bowel syndrome with... ### Lumigan **Generic:** bimatoprost Findability: 78/100 | Insurance: $0–$50 | Cash: $18–$300 What Is Lumigan (Bimatoprost)? Lumigan is the brand name for bimatoprost ophthalmic solution, a prescription eye drop used to lower intraocular pressure (IOP) in patients with open-angle glaucoma and ocular hypertension. Manufactured by Allergan (an AbbVie company), Lumigan was first approved by the FDA in 2001 and has been a first-line glaucoma treatment for over two decades. Lumigan is classified as a synthetic prostamide analog — a compound that mimics naturally occurring prostamides in... ### Lunesta **Generic:** eszopiclone Findability: 88/100 | Insurance: $0–$30 | Cash: $7–$293 What Is Lunesta? Lunesta is the brand name for eszopiclone, a prescription sleep medication FDA-approved for the treatment of insomnia in adults. It was approved by the FDA on December 15, 2004, and is one of the few approved hypnotics with clinical evidence supporting use for up to 6 months. Lunesta belongs to the class of medications called non-benzodiazepine sedative-hypnotics, often called Z-drugs. It is chemically distinct from benzodiazepines but works at the same GABA-A receptor... ### Lupron **Generic:** Lupron Findability: 40/100 | Shortage: active | Insurance: $10–$150 | Cash: $1,850–$5,500+ What Is Lupron? Lupron (Leuprolide Acetate) is a GnRH (gonadotropin-releasing hormone) agonist manufactured by AbbVie. It is used to treat advanced prostate cancer, endometriosis, uterine fibroids, and central precocious puberty in children. Lupron works by suppressing the body's production of sex hormones — testosterone in men and estrogen in women. It is administered as an injection, either in a healthcare provider's office (Lupron Depot) or as a daily self-administered subcutaneous... ### Lybalvi **Generic:** olanzapine/samidorphan Findability: 65/100 | Insurance: $0–$20 | Cash: $1,673–$2,063 What Is Lybalvi? Lybalvi (olanzapine/samidorphan) is a prescription oral tablet that combines two active ingredients: olanzapine, an atypical antipsychotic, and samidorphan, a mixed opioid antagonist/partial agonist. It was developed by Alkermes, Inc. and received FDA approval on May 28, 2021. Lybalvi is taken once daily, with or without food. Lybalvi is FDA-approved for two conditions in adults: schizophrenia, and bipolar I disorder (for acute treatment of manic or mixed episodes as... ### Lyllana **Generic:** Lyllana Findability: 40/100 | Shortage: active | Insurance: $10–$30 | Cash: $29–$210 What Is Lyllana? Lyllana is a brand-name estradiol transdermal patch manufactured by Amneal Pharmaceuticals. It delivers estradiol — the primary form of estrogen — through the skin to treat moderate to severe menopausal symptoms such as hot flashes and night sweats. Lyllana is also approved for the prevention of postmenopausal osteoporosis. The patch is applied twice weekly (every 3–4 days) to the lower abdomen or buttocks, providing a steady release of estradiol to help restore declining... ### Lymepak **Generic:** doxycycline hyclate Findability: 78/100 | Insurance: $0–$15 | Cash: $8–$80 What Is Lymepak? Lymepak is the brand name for doxycycline hyclate 100 mg film-coated oral tablets. Manufactured by Chartwell RX, LLC, it received FDA approval in 2018 (NDA 209844) as the only brand-name drug specifically developed and packaged for the treatment of early Lyme disease. It belongs to the tetracycline class of antibiotics. Lymepak is indicated for the treatment of early Lyme disease (as evidenced by erythema migrans — the characteristic bull's-eye rash) due to Borrelia... ### Lynparza **Generic:** olaparib Findability: 72/100 | Insurance: $0–$500/mo | Cash: $17,000–$20,000/mo What Is Lynparza? Lynparza (olaparib) is a targeted oral cancer therapy classified as a PARP (poly ADP-ribose polymerase) inhibitor. It was first approved by the FDA on December 19, 2014—making it the first PARP inhibitor ever approved for cancer treatment in the United States. It is manufactured by AstraZeneca. Lynparza is approved across multiple cancer types including ovarian cancer, breast cancer, pancreatic cancer, prostate cancer, and endometrial cancer. It is used primarily as a... ### Lyrica **Generic:** pregabalin Findability: 75/100 | Insurance: $10–$40 | Cash: $14–$450 What Is Lyrica (Pregabalin)? Lyrica is the brand name for pregabalin, an anticonvulsant and analgesic medication approved by the FDA in December 2004. It belongs to the class of gamma-aminobutyric acid (GABA) analogs and is classified as a Schedule V controlled substance by the DEA. Generic pregabalin has been available in the United States since July 2019. Lyrica is FDA-approved to treat neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia (nerve pain after... ### Lysodren **Generic:** mitotane Findability: 30/100 | Shortage: active | Insurance: $0–$80/mo | Cash: $3,800–$14,000+/mo What Is Lysodren? Lysodren is the brand name for mitotane, an oral adrenal cytotoxic agent. FDA-approved since 1970, it is the only drug approved by the FDA specifically for adrenocortical carcinoma (ACC) — a rare and aggressive cancer of the adrenal glands. Lysodren is manufactured by ESTEVE Pharmaceuticals S.A. and is available as 500 mg scored tablets. ACC is an extremely rare cancer, occurring in approximately 0.72 per million people per year in the United States. Because Lysodren treats... ### M-M-R II **Generic:** measles mumps and rubella virus vaccine live Findability: 45/100 | Shortage: active | Insurance: $0 | Cash: $90–$130 What Is M-M-R II? M-M-R II is the brand name for Measles, Mumps, and Rubella Virus Vaccine Live, manufactured by Merck Sharp & Dohme LLC. It is a live-attenuated combination vaccine that protects against three serious viral diseases. Approved by the FDA for individuals 12 months of age and older, M-M-R II has been in clinical use in the United States for over 40 years and is one of the most widely administered vaccines in the world. Each 0.5 mL dose contains live attenuated measles virus... ### Magnesium Aspartate **Generic:** magnesium aspartate Findability: 90/100 | Insurance: $0 | Cash: $10–$40 What Is Magnesium Aspartate? Magnesium aspartate is a dietary supplement that combines magnesium — an essential mineral — with L-aspartic acid, an amino acid. Its chemical formula is Mg(C4H6NO4)2(H2O)2. It is available over the counter under the brand names Maginex (tablet) and Maginex DS (dissolvable powder). Generic versions are also widely sold. Magnesium is involved in over 300 enzymatic reactions in the body, including energy production (ATP synthesis), protein synthesis, DNA... ### Magnesium Citrate **Generic:** magnesium citrate Findability: 92/100 | Insurance: $0–$10 | Cash: $5–$15 What Is Magnesium Citrate? Magnesium citrate is a compound formed by combining magnesium — an essential mineral — with citric acid. It serves two distinct purposes: as a saline osmotic laxative for constipation and colonoscopy bowel preparation, and as a dietary supplement to replenish magnesium levels in the body. It is available entirely over the counter in the United States — no prescription required. Brand names include Citroma, Citrate of Magnesia, and ColonX. Generic store brands from... ### Magnesium Glycinate **Generic:** magnesium glycinate Findability: 88/100 | Insurance: $0 | Cash: $8–$40 What Is Magnesium Glycinate? Magnesium Glycinate (also called magnesium bisglycinate or magnesium diglycinate) is an over-the-counter dietary supplement made by chemically bonding elemental magnesium to two molecules of glycine, an amino acid. This chelated form of magnesium is one of the most bioavailable and best-tolerated magnesium supplements available, as the glycine bond stabilizes the magnesium through digestion and significantly improves absorption through the small... ### Malarone **Generic:** atovaquone/proguanil Findability: 75/100 | Insurance: $0–$60 | Cash: $43–$272 What Is Malarone? Malarone is the brand name for atovaquone/proguanil, a combination antimalarial medication manufactured by GlaxoSmithKline (GSK). It was approved by the FDA in 2000 and is one of the most widely recommended antimalarials for travelers. Generic atovaquone/proguanil has been available in the US since approximately 2011 and is FDA-approved as bioequivalent to the brand-name product. Malarone comes in two tablet strengths: the adult tablet (250 mg atovaquone / 100 mg proguanil... ### Malathion **Generic:** malathion Findability: 45/100 | Insurance: $10–$60 | Cash: $76–$260 What Is Malathion? Malathion (brand name Ovide) is a prescription topical medication used to treat head lice (Pediculus humanus capitis) and their eggs (nits) in adults and children 6 years of age and older. It belongs to a class of drugs called organophosphate pediculicides — medications that kill parasitic insects by disrupting their nervous system. Malathion was first approved by the FDA in 1982 under the brand name Ovide. A generic version was FDA-approved in 2009 and is considered... ### Mannitol **Generic:** Mannitol Findability: 40/100 | Shortage: active | Insurance: $0–$50 | Cash: $12–$135 What Is Mannitol? Mannitol is an osmotic diuretic — a sugar alcohol used primarily in hospital settings to reduce dangerously elevated intracranial pressure (brain swelling) and intraocular pressure (eye pressure). It is administered intravenously under the brand name Osmitrol. Mannitol is also available as an inhaled formulation (Bronchitol) for add-on maintenance treatment of cystic fibrosis, where it helps hydrate airway secretions and improve lung function. Another inhaled form (Aridol)... ### Mar-Cof CG **Generic:** codeine phosphate and guaifenesin Findability: 65/100 | Insurance: $0–$20 | Cash: $11–$22 What Is Mar-Cof CG? Mar-Cof CG is a prescription combination cough syrup manufactured by Marnel Pharmaceuticals, LLC and distributed by Allegis Pharmaceuticals, LLC. Each 5 mL (one teaspoon) contains codeine phosphate 7.5 mg and guaifenesin 225 mg. The formulation is alcohol-free and sugar-free, making it suitable for patients who need to avoid these ingredients. Mar-Cof CG is used for the temporary relief of cough and chest congestion caused by the common cold, flu, or allergies. It is a DEA... ### Marinol **Generic:** Marinol Findability: 45/100 | Shortage: active | Insurance: $10–$75 | Cash: $58–$800 What Is Marinol? Marinol is the brand name for Dronabinol, a synthetic form of delta-9-tetrahydrocannabinol (THC). It is FDA-approved for two conditions: anorexia associated with weight loss in patients with AIDS, and nausea and vomiting caused by cancer chemotherapy in patients who have not responded to conventional antiemetic treatments. Marinol comes as a capsule that contains Dronabinol dissolved in sesame oil. ### Marplan **Generic:** Marplan Findability: 30/100 | Shortage: active | Insurance: $20–$200 | Cash: $577–$700 What Is Marplan? Marplan (Isocarboxazid) is a monoamine oxidase inhibitor (MAOI) antidepressant manufactured by Validus Pharmaceuticals. It is FDA-approved for the treatment of major depressive disorder, specifically in patients who have not responded to other antidepressants. Marplan is considered a last-line treatment option due to its significant dietary restrictions and drug interaction profile. It may also be used off-label for atypical depression, panic disorder, social phobia, and... ### Mavyret **Generic:** glecaprevir/pibrentasvir Findability: 72/100 | Insurance: $5–$2,100 | Cash: $14,000–$17,000 What Is Mavyret? Mavyret is a prescription antiviral medication manufactured by AbbVie. Its active ingredients are glecaprevir (100 mg) and pibrentasvir (40 mg), a fixed-dose combination of two direct-acting antivirals (DAAs). It is the first and only pangenotypic direct-acting antiviral approved by the FDA to treat both acute and chronic hepatitis C virus (HCV) infection in adults and children 3 years and older. First approved in August 2017 for chronic HCV, Mavyret received a major label... ### Maxitrol **Generic:** neomycin/polymyxin b/dexamethasone ophthalmic Findability: 78/100 | Insurance: $0–$30 | Cash: $8–$162 What Is Maxitrol? Maxitrol is a brand-name prescription ophthalmic medication that combines two antibiotics — neomycin (3.5 mg/mL) and polymyxin B (10,000 units/mL) — with the corticosteroid dexamethasone (0.1%). This triple-action formula fights bacterial eye infections while simultaneously reducing inflammation, pain, redness, and swelling. The brand is distributed by Alcon Laboratories and has been FDA-approved since October 1964. Generic versions (neomycin/polymyxin B/dexamethasone... ### Mebendazole **Generic:** mebendazole Findability: 42/100 | Insurance: $5–$150 | Cash: $5–$5,258 What Is Mebendazole? Mebendazole is a broad-spectrum anthelmintic (anti-worm) medication belonging to the benzimidazole drug class. It was first developed in 1971 by Janssen Pharmaceutica in Belgium and received FDA approval in the United States in 1974. It is on the World Health Organization's List of Essential Medicines, reflecting its critical importance to global public health. In the United States, mebendazole is available under the brand name Emverm (100 mg chewable tablet) manufactured... ### Mecobalamin **Generic:** mecobalamin Findability: 72/100 | Insurance: $0–$30 | Cash: $5–$93 What Is Mecobalamin? Mecobalamin — also known as methylcobalamin, MeCbl, or MeB12 — is the biologically active form of vitamin B12. Unlike cyanocobalamin, the most commonly used synthetic form of B12, mecobalamin is ready for immediate use by the body without requiring hepatic conversion. It is the principal form of B12 circulating in the bloodstream and the form directly involved in nervous system function. Mecobalamin is used to treat vitamin B12 deficiency, pernicious anemia, peripheral... ### Mefloquine **Generic:** mefloquine Findability: 42/100 | Shortage: active | Insurance: $0–$50 | Cash: $33–$120 What Is Mefloquine? Mefloquine hydrochloride is an oral prescription antimalarial medication used to prevent and treat malaria caused by Plasmodium falciparum and Plasmodium vivax. Originally developed by the U.S. military at the Walter Reed Army Institute of Research in the 1970s, it was first approved by the FDA in May 1989 and was previously marketed under the brand name Lariam by Roche. The brand name Lariam was withdrawn from the U.S. market in August 2009, and today only generic... ### Megestrol **Generic:** megestrol acetate Findability: 35/100 | Shortage: active | Insurance: $0–$30 | Cash: $18–$255 What Is Megestrol? Megestrol acetate (brand names Megace and Megace ES) is a synthetic progestin medication with two primary FDA-approved uses. The oral suspension formulation is approved to treat anorexia, cachexia, and unexplained significant weight loss in people living with HIV/AIDS. The tablet formulation is approved for palliative management of advanced, inoperable, or metastatic breast cancer and endometrial carcinoma. Megestrol has been FDA-approved since 1971 (endometrial cancer) and... ### Menest **Generic:** esterified estrogens Findability: 55/100 | Insurance: $10–$60 | Cash: $86–$180 What Is Menest? Menest is a brand-name oral estrogen medication manufactured by Pfizer. Its generic name is esterified estrogens — a mixture of synthetic estrogen compounds derived from both equine (horse) and plant sources, including sodium estrone sulfate and sodium equilin sulfate. Menest has been used for decades to help women manage hormonal changes during menopause and related conditions. Menest is FDA-approved for moderate to severe menopausal vasomotor symptoms (hot flashes, night... ### Mephyton **Generic:** phytonadione Findability: 55/100 | Insurance: $0–$15 | Cash: $21–$80 What Is Mephyton (Phytonadione)? Mephyton is the brand name for phytonadione—a synthetic, prescription-strength form of vitamin K1. It is used to treat vitamin K deficiency and conditions that prevent normal blood clotting. The Mephyton brand has been discontinued, but generic phytonadione 5 mg oral tablets remain available from multiple manufacturers. Phytonadione is FDA-approved to treat anticoagulant-induced hypoprothrombinemia (including warfarin overdose), hypoprothrombinemia from... ### Meprobamate **Generic:** Meprobamate Findability: 45/100 | Shortage: active | Insurance: $15–$60 | Cash: $97–$671 What Is Meprobamate? Meprobamate is a carbamate-derivative anxiolytic (tranquilizer) approved by the FDA for the management of anxiety disorders and the short-term relief of anxiety symptoms. It was one of the first widely prescribed anti-anxiety medications, introduced in the 1950s under the brand names Miltown and Equanil. While it has largely been replaced by benzodiazepines and newer anxiolytics, some patients and providers still rely on Meprobamate when other treatments are not suitable.... ### Mesalamine XR **Generic:** mesalamine Findability: 38/100 | Shortage: active | Insurance: $0–$30 | Cash: $38–$560 What Is Mesalamine XR? Mesalamine XR is the extended-release formulation of mesalamine, also known as 5-aminosalicylic acid (5-ASA) or mesalazine. It is an aminosalicylate medication used primarily to treat and maintain remission of mild to moderately active ulcerative colitis (UC) in adults. Mesalamine works locally in the intestinal lining to reduce inflammation without suppressing the immune system. Brand names for mesalamine extended-release capsules include Pentasa (250 mg and 500 mg, by... ### Mestinon **Generic:** Mestinon Findability: 60/100 | Shortage: monitoring | Insurance: $5–$100 | Cash: $26–$750 What Is Mestinon? Mestinon (Pyridostigmine Bromide) is a cholinesterase inhibitor primarily used to treat myasthenia gravis, a chronic autoimmune neuromuscular disease that causes muscle weakness and fatigue. It works by improving the communication between nerves and muscles, helping patients regain strength for everyday activities like breathing, swallowing, and moving. Mestinon is also used off-label for conditions like postural orthostatic tachycardia syndrome (POTS), Long COVID autonomic... ### Metadate Cd **Generic:** Metadate Cd Findability: 40/100 | Shortage: active | Insurance: $15–$75 | Cash: $33–$235 What Is Metadate Cd? Metadate Cd (methylphenidate hydrochloride extended-release) is a central nervous system (CNS) stimulant approved by the FDA for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients aged 6 to 15 years. It is also used off-label for ADHD in adults and adolescents older than 15, as well as for narcolepsy and treatment-resistant depression. Metadate Cd uses a unique dual-bead delivery system with 30% immediate-release beads and 70%... ### Metaxalone **Generic:** metaxalone Findability: 78/100 | Insurance: $0–$60 | Cash: $20–$184 What Is Metaxalone? Metaxalone (brand name Skelaxin) is a prescription centrally acting skeletal muscle relaxant first approved by the FDA in 1962. It is used as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions such as muscle strains, sprains, and back spasms. Metaxalone is distinctive within the muscle relaxant class because it is generally considered the least sedating option available. This makes... ### Methocarbamol **Generic:** methocarbamol Findability: 68/100 | Insurance: $0–$15 | Cash: $5–$30 What Is Methocarbamol? Methocarbamol is a centrally-acting skeletal muscle relaxant that has been FDA-approved since July 16, 1957. It is most commonly known by its former brand name Robaxin (the brand was discontinued by Endo Pharmaceuticals in January 2020, though generic Methocarbamol remains widely available). In 2023, Methocarbamol was the 121st most commonly prescribed medication in the United States, with more than 5 million prescriptions filled annually. Methocarbamol is FDA-approved... ### Methotrexate **Generic:** methotrexate Findability: 35/100 | Shortage: active | Insurance: $0–$30 | Cash: $5–$110 What Is Methotrexate? Methotrexate (MTX) is a folic acid antagonist and antimetabolite drug first approved by the FDA in 1953. It is one of the most versatile medications in modern medicine, used as both a disease-modifying antirheumatic drug (DMARD) for autoimmune conditions and as a chemotherapy agent for certain cancers. At low weekly doses (7.5–25 mg once weekly), methotrexate is the first-line DMARD for rheumatoid arthritis, psoriatic arthritis, and severe psoriasis. It slows disease... ### Methscopolamine **Generic:** methscopolamine bromide Findability: 62/100 | Insurance: $10–$50 | Cash: $45–$185 What Is Methscopolamine? Methscopolamine bromide is a prescription anticholinergic medication used as adjunctive therapy for peptic ulcer disease in adults. It is a quaternary ammonium derivative of scopolamine — chemically modified to act primarily in the peripheral nervous system (especially the GI tract) rather than crossing into the brain. The brand-name versions Pamine and Pamine Forte have been discontinued. Generic methscopolamine bromide tablets (2.5 mg and 5 mg) remain available from... ### Methylin **Generic:** methylphenidate Findability: 38/100 | Shortage: active | Insurance: $10–$50 | Cash: $20–$150 What Is Methylin? Methylin is a brand name for methylphenidate hydrochloride, a central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. It belongs to the same drug class as Ritalin and Concerta. Methylin was specifically formulated as an oral solution (5 mg/5 mL and 10 mg/5 mL) and chewable tablets (2.5, 5, and 10 mg) — forms particularly useful for children or adults who have difficulty swallowing standard tablets. Methylphenidate... ### Methylphenidate **Generic:** Methylphenidate Findability: 42/100 | Shortage: active | Insurance: $10–$40 | Cash: $23–$57 What Is Methylphenidate? Methylphenidate is a prescription stimulant medication used to treat ADHD and narcolepsy. It is the active ingredient in Ritalin, Concerta, Ritalin LA, Metadate CD, Quillivant XR, Jornay PM, Cotempla XR-ODT, and Daytrana. First approved by the FDA in 1955, methylphenidate has over 60 years of clinical data supporting its safety and efficacy. It is one of the two main classes of stimulant ADHD medications, alongside amphetamine-based drugs. Stimulant medications are... ### Methylphenidate XR **Generic:** Methylphenidate XR Findability: 45/100 | Shortage: active | Insurance: $5–$30 | Cash: $39–$400+ What Is Methylphenidate XR? Methylphenidate XR is a central nervous system (CNS) stimulant prescribed primarily for Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 and older, adolescents, and adults. It is the extended-release formulation of methylphenidate hydrochloride, designed to provide symptom control throughout the day with a single dose. Methylphenidate XR is available under multiple brand names including Concerta, Ritalin LA, Metadate CD, Aptensio XR, Adhansia XR,... ### Metoclopramide **Generic:** metoclopramide Findability: 82/100 | Insurance: $0–$15 | Cash: $4–$20 What Is Metoclopramide? Metoclopramide is a prescription prokinetic agent and antiemetic (anti-nausea medication) that has been FDA-approved since 1979. It is classified as a dopamine D2 receptor antagonist, and it works by blocking dopamine receptors both in the brain's chemoreceptor trigger zone (reducing nausea signals) and in the gastrointestinal tract (accelerating gastric emptying). It is the only FDA-approved oral medication for diabetic gastroparesis. The best-known brand name is... ### Metolazone **Generic:** metolazone Findability: 72/100 | Insurance: $0–$20 | Cash: $12–$85 What Is Metolazone? Metolazone is a quinazoline diuretic (water pill) belonging to the thiazide-like class of medications. It is FDA-approved to treat fluid retention (edema) caused by congestive heart failure or chronic kidney disease, and to manage high blood pressure (hypertension) alone or in combination with other antihypertensive medications. Originally sold under brand names Zaroxolyn, Mykrox, and Diulo — all of which have been discontinued — metolazone is now available exclusively as... ### Metoprolol **Generic:** metoprolol Findability: 88/100 | Insurance: $0–$20 | Cash: $4–$65 What Is Metoprolol? Metoprolol is a prescription beta-blocker used to treat several cardiovascular conditions, including high blood pressure (hypertension), chest pain (angina pectoris), heart failure with reduced ejection fraction (HFrEF), and to reduce mortality after a heart attack. It is one of the most commonly prescribed medications in the United States. Metoprolol is available in two distinct salt forms that are not interchangeable: metoprolol tartrate (immediate-release, brand name... ### MetroCream **Generic:** metronidazole topical cream Findability: 80/100 | Insurance: $0–$30 | Cash: $25–$93 What Is MetroCream? MetroCream is the brand name for metronidazole 0.75% topical cream, a prescription medication used to treat rosacea. It was FDA-approved for the treatment of inflammatory papules and pustules of rosacea in September 1997. MetroCream is classified as a nitroimidazole topical antibiotic with anti-inflammatory properties. Rosacea is a chronic skin condition causing redness, bumps, and visible blood vessels primarily on the nose, cheeks, forehead, and chin. MetroCream helps... ### MetroGel **Generic:** metronidazole topical Findability: 82/100 | Insurance: $0–$30 | Cash: $22–$186 What Is MetroGel? MetroGel is the brand name for metronidazole topical gel, an antibiotic medication applied directly to the skin to treat rosacea. It is manufactured by Galderma and comes in two concentrations: 0.75% gel (applied twice daily) and 1% gel (applied once daily). The 1% formulation is the primary branded MetroGel product. MetroGel (metronidazole 1% topical gel) is FDA-approved for the treatment of inflammatory lesions (papules and pustules) associated with rosacea — a chronic... ### Metronidazole **Generic:** metronidazole Findability: 88/100 | Insurance: $0–$15 | Cash: $4–$28 What Is Metronidazole? Metronidazole is a nitroimidazole antimicrobial agent first FDA-approved in 1963. Known by the brand name Flagyl, it is one of the most widely prescribed antibiotics in the world. It is available as an affordable generic and is used to treat a broad range of bacterial and protozoal (parasitic) infections. Metronidazole treats infections of the reproductive system (bacterial vaginosis, trichomoniasis, pelvic inflammatory disease), gastrointestinal tract (C. diff,... ### Mexiletine **Generic:** mexiletine Findability: 75/100 | Shortage: resolved | Insurance: $0–$30 | Cash: $31–$140 What Is Mexiletine? Mexiletine hydrochloride (formerly sold as brand name Mexitil, now discontinued) is an oral prescription medication classified as a Class 1B antiarrhythmic agent. It is used primarily to treat life-threatening ventricular arrhythmias — abnormal heart rhythms originating in the lower chambers of the heart. Mexiletine is structurally similar to lidocaine and is often described as the oral equivalent of that well-known local anesthetic. Mexiletine is available only as a... ### MicRhoGAM **Generic:** rho(d) immune globulin (human) mini-dose Findability: 45/100 | Shortage: active | Insurance: $0–$50 | Cash: $100–$300 What Is MicRhoGAM? MicRhoGAM (Rho(D) immune globulin human, mini-dose) is a biological medication made from human blood plasma. It contains concentrated IgG antibodies against the Rh(D) antigen — a protein found on the red blood cells of Rh-positive individuals. MicRhoGAM is the mini-dose formulation containing 50 mcg (250 IU), designed specifically for early pregnancy events at or before 12 weeks of gestation. MicRhoGAM is manufactured by Kedrion Biopharma Inc. and has been FDA-approved... ### Micafungin **Generic:** micafungin Findability: 72/100 | Insurance: $0–$200 | Cash: $28–$150 What Is Micafungin? Micafungin (brand name Mycamine) is an intravenous antifungal medication belonging to the echinocandin drug class. It was first approved by the FDA in 2005 and is manufactured by Astellas Pharma under the Mycamine brand name, with generic versions now available from multiple manufacturers. It is indicated for the treatment and prevention of serious Candida fungal infections in adults and pediatric patients, including neonates less than 4 months old. Micafungin is... ### Midazolam **Generic:** midazolam Findability: 62/100 | Insurance: $0–$100+ | Cash: $9–$800 What Is Midazolam? Midazolam is a short-acting benzodiazepine medication that calms the central nervous system. First FDA-approved in 1985, it is on the World Health Organization's List of Essential Medicines and is one of the most widely used sedatives in healthcare. The original brand name Versed has been discontinued, but generic forms remain widely available in injectable and oral formulations. Active brand names include Nayzilam (midazolam nasal spray for seizure clusters) and Seizalam... ### Miebo **Generic:** perfluorohexyloctane Findability: 72/100 | Insurance: $0–$60 | Cash: $778–$1,248 What Is Miebo? Miebo is the brand name for perfluorohexyloctane ophthalmic solution, a prescription eye drop manufactured by Bausch + Lomb. It was FDA-approved in May 2023 for the treatment of the signs and symptoms of dry eye disease (DED) in adults. Miebo contains 100% perfluorohexyloctane — it is entirely water-free and preservative-free, making it unlike any other dry eye medication on the market. Miebo is the first and only FDA-approved prescription eye drop that directly targets tear... ### Mifeprex **Generic:** mifepristone Findability: 35/100 | Shortage: active | Insurance: $0–$50 | Cash: $150–$800 What Is Mifeprex? Mifeprex is the brand name for mifepristone, a 200 mg oral tablet approved by the FDA on September 28, 2000. It is used in combination with misoprostol to end an intrauterine pregnancy through 70 days (10 weeks) of gestation — a regimen known as medication abortion. The combination is approximately 97% effective in the first 63 days of pregnancy. Mifeprex is manufactured by Danco Laboratories and is also available as a generic from GenBioPro (approved 2019) and Evita... ### Mifepristone **Generic:** mifepristone Findability: 40/100 | Shortage: active | Insurance: $0–$30 | Cash: $50–$800 What Is Mifepristone? Mifepristone is a synthetic steroid with two FDA-approved uses. Under the brand name Mifeprex, it is used in combination with misoprostol for medical termination of pregnancy through 70 days (10 weeks) gestation — a regimen used in approximately two-thirds of all US abortions. Under the brand name Korlym, it is used to control hyperglycemia caused by excess cortisol in adults with endogenous Cushing's syndrome who have type 2 diabetes and have failed surgery or cannot... ### Millipred **Generic:** prednisolone Findability: 45/100 | Shortage: active | Insurance: $0–$10 | Cash: $5–$50 What Is Millipred? Millipred is a brand-name formulation of prednisolone, a synthetic corticosteroid that has been FDA-approved since 1955. It is available as scored 5 mg tablets and as an oral solution (10 mg prednisolone per 5 mL, grape-flavored). Prednisolone belongs to the glucocorticoid class of medications and mimics cortisol, a hormone the adrenal glands naturally produce. Millipred is prescribed for a remarkably broad range of conditions — from childhood asthma and croup to rheumatoid... ### Milnacipran **Generic:** milnacipran Findability: 72/100 | Insurance: $20–$150 | Cash: $40–$766 What Is Milnacipran (Savella)? Milnacipran is the generic name for the brand-name drug Savella. It is a serotonin-norepinephrine reuptake inhibitor (SNRI) and one of only three FDA-approved medications for fibromyalgia in the United States. The FDA granted approval in January 2009 for the management of fibromyalgia in adults. Unlike related SNRIs such as duloxetine and venlafaxine, Milnacipran is not FDA-approved for depression in the United States — though it is used for this purpose in... ### Minastrin 24 Fe Chewable 28 Day **Generic:** norethindrone acetate / ethinyl estradiol / ferrous fumarate Findability: 55/100 | Shortage: active | Insurance: $0–$15 | Cash: $20–$163 What Is Minastrin 24 Fe Chewable 28 Day? Minastrin 24 Fe is a combination oral contraceptive (birth control pill) that was manufactured by Allergan, an AbbVie company. It contains two synthetic hormones: norethindrone acetate (1 mg, a progestin) and ethinyl estradiol (20 mcg, an estrogen). Each 28-day pack contains 24 white active chewable tablets and 4 brown iron (ferrous fumarate 75 mg) placebo tablets. Minastrin 24 Fe is unique in that its active tablets are chewable and... ### Mineral Oil **Generic:** mineral oil Findability: 92/100 | Insurance: Not typically covered | Cash: $6–$20 What Is Mineral Oil? Mineral oil is an over-the-counter lubricant laxative derived from highly refined petroleum. It is a colorless, odorless liquid taken orally (or administered rectally as an enema) to relieve occasional constipation. Mineral oil is sold under several brand names including Fleet Mineral Oil, Kondremul Plain, Milkinol, and numerous store brands. No prescription is required to purchase mineral oil. It is regulated by the FDA under OTC Monograph M007 for laxative drug... ### Minoxidil **Generic:** Minoxidil Findability: 55/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $4–$50 What Is Minoxidil? Minoxidil is a direct-acting peripheral vasodilator and potassium channel opener. In its oral form, it is FDA-approved for the treatment of severe refractory hypertension — specifically for patients who have not responded adequately to maximum doses of a diuretic and two other antihypertensive medications. In its topical form (marketed as Rogaine and generic equivalents), it is FDA-approved for androgenetic alopecia (pattern hair loss). Increasingly, low-dose oral Minoxidil... ### Mirabegron XR **Generic:** mirabegron Findability: 50/100 | Insurance: $0–$100 | Cash: $121–$625 What Is Mirabegron XR? Mirabegron XR is the extended-release formulation of mirabegron, a prescription medication used to treat overactive bladder (OAB) in adults. It is sold under the brand name Myrbetriq by Astellas Pharma and was first approved by the FDA in June 2012 — making it the first beta-3 adrenergic agonist approved for OAB in the United States. A generic version (mirabegron extended-release) became available in late 2022 following patent expiration, though supply is currently... ### Mircette 28 Day **Generic:** desogestrel/ethinyl estradiol Findability: 55/100 | Insurance: $0–$15 | Cash: $60–$120 What Is Mircette 28 Day? Mircette 28 Day is an FDA-approved biphasic combined oral contraceptive (COC) containing two synthetic hormones: desogestrel (a third-generation progestin) and ethinyl estradiol (a synthetic estrogen). It was originally marketed under the brand name Mircette by Organon, but that brand has been discontinued. The medication lives on through multiple FDA-approved generic equivalents: Kariva, Azurette, Viorele, Volnea, Pimtrea, Kimidess, Bekyree, and Simliya. Mircette 28... ### Mirena **Generic:** levonorgestrel Findability: 72/100 | Insurance: $0–$50 | Cash: $1,200–$1,725 What Is Mirena? Mirena is a brand-name intrauterine device (IUD) manufactured by Bayer. It contains 52 mg of levonorgestrel — a synthetic progestin hormone — that is slowly released into the uterine cavity over time. Mirena was first FDA-approved in December 2000, making it the first and longest-studied hormonal IUD on the U.S. market. Mirena is a small, T-shaped plastic device approximately the size of a paper clip. A trained healthcare provider inserts it into the uterus during a brief... ### Mirtazapine **Generic:** mirtazapine Findability: 85/100 | Insurance: $0–$20 | Cash: $5–$70 What Is Mirtazapine? Mirtazapine (brand names: Remeron, Remeron SolTab) is an atypical tetracyclic antidepressant — sometimes called a NaSSA (Noradrenergic and Specific Serotonergic Antidepressant) — FDA-approved in 1996 to treat major depressive disorder (MDD) in adults. It works by blocking specific receptors in the brain to increase the availability of both serotonin and norepinephrine, two neurotransmitters closely linked to mood regulation. Mirtazapine is not a first-line antidepressant... ### Misoprostol **Generic:** misoprostol Findability: 78/100 | Insurance: $0–$20 | Cash: $7–$50 What Is Misoprostol? Misoprostol is a synthetic prostaglandin E1 analog — a lab-engineered version of a naturally occurring signaling compound in the body. It was first approved by the FDA on December 27, 1988, under the brand name Cytotec (Pfizer) to prevent stomach ulcers in patients who take nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen. Beyond its FDA-approved GI indication, misoprostol is widely used off-label for medical abortion (with mifepristone or alone),... ### Mobic **Generic:** meloxicam Findability: 92/100 | Insurance: $0–$20 | Cash: $10–$30 What Is Meloxicam (Mobic)? Meloxicam is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with arthritis. Originally marketed under the brand name Mobic (now discontinued in the U.S.), it is available as generic meloxicam tablets, capsules, and oral suspension. The FDA has approved meloxicam for osteoarthritis (OA) in adults, rheumatoid arthritis (RA) in adults, and juvenile rheumatoid arthritis (JRA/JIA) in children 2 years and older.... ### Molnupiravir **Generic:** molnupiravir Findability: 72/100 | Insurance: $0–$50 | Cash: $1,042–$1,100 What Is Molnupiravir (Lagevrio)? Molnupiravir, sold under the brand name Lagevrio, is an oral antiviral medication developed by Merck in collaboration with Ridgeback Biotherapeutics. It is authorized in the United States under an FDA Emergency Use Authorization (EUA) — not a full FDA approval — for the treatment of mild-to-moderate COVID-19 in adults at high risk for disease progression. The drug was originally developed at Emory University to treat influenza and was repurposed for COVID-19... ### Monovisc **Generic:** hyaluronan Findability: 62/100 | Insurance: $100–$350 | Cash: $1,521–$2,047 What Is Monovisc? Monovisc is a single-injection viscosupplement used to treat pain caused by knee osteoarthritis (OA). It contains high molecular weight, cross-linked sodium hyaluronate — a form of hyaluronic acid (HA) derived from bacterial fermentation — delivered as a single 4 mL intra-articular injection. Monovisc is manufactured by Anika Therapeutics, Inc. and distributed in the U.S. by DePuy Synthes (Johnson & Johnson). The FDA cleared Monovisc as a Class III medical device (PMA... ### Montelukast **Generic:** montelukast Findability: 85/100 | Insurance: $0–$30 | Cash: $15–$145 What Is Montelukast? Montelukast is a prescription leukotriene receptor antagonist (LTRA) sold under the brand name Singulair. It was first FDA-approved in 1998 by Merck, and generic versions have been widely available since August 2012, when the original patent expired. Approximately 9.3 million U.S. patients receive dispensed prescriptions for montelukast annually, making it one of the most commonly prescribed medications in the country. Montelukast is FDA-approved for four indications:... ### Morning After Pill **Generic:** levonorgestrel Findability: 90/100 | Insurance: $0–$15 | Cash: $11–$50 What Is the Morning After Pill? The morning after pill is emergency contraception—a medication taken after unprotected sex or contraceptive failure to reduce the chance of pregnancy. There are two main types available in the U.S.: levonorgestrel (Plan B One-Step and numerous generics, available OTC) and ulipristal acetate (ella, available by prescription). Levonorgestrel pills such as Plan B One-Step contain 1.5 mg of a synthetic progestin hormone. They are effective for up to 72 hours after... ### Motpoly XR **Generic:** lacosamide Findability: 55/100 | Insurance: $10–$100 | Cash: $1,143–$1,565 What Is Motpoly XR? Motpoly XR is the brand name for lacosamide extended-release capsules, manufactured by Aucta Pharmaceuticals, Inc. (Piscataway, NJ). It is an antiepileptic drug (AED) — a class of medications used to prevent and control seizures in people with epilepsy. The active ingredient, lacosamide, was first approved by the FDA in 2008 as Vimpat (immediate-release). Motpoly XR is the extended-release formulation, FDA-approved on May 4, 2023, offering once-daily dosing as a clinical... ### Mounjaro **Generic:** Mounjaro Findability: 60/100 | Shortage: monitoring | Insurance: $25–$150 | Cash: $550–$1,060 What Is Mounjaro? Mounjaro (tirzepatide) is a prescription injectable medication FDA-approved in May 2022 for type 2 diabetes, manufactured by Eli Lilly. It is the first and only dual GIP/GLP-1 receptor agonist. In clinical trials, Mounjaro achieved average A1C reductions of 2.0–2.3% and weight loss of 15–25 pounds. Up to 50% of patients reached non-diabetic A1C levels. Its sister drug Zepbound contains the same active ingredient but is approved for weight management. Medfinder helps you... ### Moxifloxacin **Generic:** moxifloxacin Findability: 52/100 | Shortage: active | Insurance: $5–$30 | Cash: $11–$130 What Is Moxifloxacin? Moxifloxacin is a broad-spectrum prescription antibiotic in the fluoroquinolone class. Originally sold under the brand name Avelox (manufactured by Bayer AG), it has been available only in generic form since the brand was discontinued. The FDA approved moxifloxacin in 1999, making it one of the newer fluoroquinolones with enhanced activity against gram-positive bacteria and anaerobic organisms. Moxifloxacin is FDA-approved for community-acquired pneumonia (CAP), acute... ### Mupirocin **Generic:** mupirocin Findability: 88/100 | Insurance: $0–$20 | Cash: $5–$77 What Is Mupirocin? Mupirocin is a prescription topical antibiotic used to treat bacterial skin infections. Previously sold under the brand names Bactroban and Centany — both now discontinued — it is widely available as a generic medication. Mupirocin is listed on the World Health Organization's List of Essential Medicines and was first FDA-approved in 1987. It comes in two formulations: a 2% ointment (in 15g and 22g tubes) for treating impetigo, and a 2% cream (in 15g and 30g tubes) for... ### Mycophenolate Mofetil **Generic:** mycophenolate mofetil Findability: 45/100 | Shortage: active | Insurance: $5–$88 | Cash: $22–$419 What Is Mycophenolate Mofetil? Mycophenolate mofetil (brand name CellCept) is an immunosuppressant medication approved by the FDA in 1995. It belongs to a class of drugs called selective IMPDH inhibitors and is used to prevent the immune system from rejecting transplanted organs or attacking the body's own tissues in autoimmune disease. It is available as a generic from multiple manufacturers and as brand-name CellCept from Genentech (Roche). Mycophenolate mofetil is FDA-approved for... ### Mycophenolic Acid **Generic:** mycophenolic acid Findability: 72/100 | Insurance: $0–$50 | Cash: $18–$900 What Is Mycophenolic Acid? Mycophenolic acid (MPA) is an immunosuppressant medication used to prevent organ rejection after transplantation. It is available in two main forms in the United States: Myfortic (mycophenolate sodium), an enteric-coated delayed-release tablet, and as the active metabolite of mycophenolate mofetil (CellCept), a prodrug that converts to MPA in the body. Both are approved for kidney transplant rejection prevention; CellCept is additionally approved for heart and liver... ### Mydayis **Generic:** Mydayis Findability: 55/100 | Shortage: monitoring | Insurance: $30–$75 | Cash: $92–$352 What Is Mydayis? Mydayis is a prescription stimulant medication used to treat ADHD in adolescents (ages 13+) and adults. It contains the same mixed amphetamine salts as Adderall XR but uses a triple-bead extended-release system that provides up to 16 hours of coverage — significantly longer than Adderall XR's 8–10 hours. Originally manufactured by Shire (now part of Takeda), Mydayis was FDA-approved in 2017. A generic version is available, making it more accessible and affordable. Mydayis is... ### Myfortic **Generic:** Myfortic Findability: 55/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $43–$900 What Is Myfortic? Myfortic is the brand name for mycophenolic acid (as mycophenolate sodium) in a delayed-release tablet formulation. It belongs to the class of selective immunosuppressants known as IMPDH inhibitors. Myfortic is FDA-approved for the prevention of organ rejection in adult patients who have received kidney transplants, and in pediatric patients aged 5 and older who are at least 6 months post kidney transplant. It is always used in combination with cyclosporine and... ### Myobloc **Generic:** rimabotulinumtoxinB Findability: 65/100 | Insurance: $0–$500 | Cash: $1,244–$1,777 What Is Myobloc? Myobloc is the brand name for rimabotulinumtoxinB, the only FDA-approved botulinum toxin type B product in the United States. It is an injectable prescription medication manufactured by Solstice Neurosciences (a subsidiary of Supernus Pharmaceuticals) and administered exclusively by trained healthcare providers. Myobloc was first approved by the FDA in December 2000 for cervical dystonia — a painful neurological movement disorder causing involuntary neck muscle contractions... ### Myrbetriq **Generic:** mirabegron Findability: 72/100 | Insurance: $0–$50 | Cash: $117–$625 What Is Myrbetriq? Myrbetriq is the brand name for mirabegron, an extended-release tablet manufactured by Astellas Pharma US, Inc. It was first approved by the FDA in 2012 for the treatment of overactive bladder (OAB) in adults, and later expanded in 2021 to include pediatric patients with neurogenic detrusor overactivity (NDO). A generic version of mirabegron extended-release became available in the U.S. market beginning in early 2024. Myrbetriq belongs to a drug class called beta-3... ### Nabumetone **Generic:** nabumetone Findability: 82/100 | Insurance: $0–$20 | Cash: $15–$80 What Is Nabumetone? Nabumetone is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation associated with osteoarthritis and rheumatoid arthritis. Originally sold under the brand name Relafen — now discontinued — it is available today only as a generic, in 500 mg, 750 mg, and 1,000 mg oral tablets. The 1,000 mg strength is also available as Relafen DS. The FDA approved nabumetone in December 1991. It is prescribed to adults with osteoarthritis or... ### Naltrexone **Generic:** naltrexone Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $32–$168 What Is Naltrexone? Naltrexone is an FDA-approved prescription medication used to treat alcohol use disorder (AUD) and opioid use disorder (OUD). It belongs to a class of drugs called opioid antagonists — medications that block the effects of opioids and reduce the rewarding effects of alcohol. Naltrexone is available as a 50 mg oral tablet taken once daily (generic only; brand-name ReVia and Depade have been discontinued) and as Vivitrol, a 380 mg extended-release injectable administered... ### Naphazoline **Generic:** naphazoline Findability: 88/100 | Insurance: Not typically covered | Cash: $7–$20 What Is Naphazoline? Naphazoline is a sympathomimetic vasoconstrictor used in over-the-counter eye drops and nasal decongestants. It acts on alpha-adrenergic receptors in blood vessel walls to produce rapid vasoconstriction, reducing the visible redness of the eyes and swelling in the nasal passages. First patented in 1934 and entering clinical use in 1942, it is one of the oldest compounds in OTC eye care. Standalone naphazoline was discontinued by its US manufacturers as a business decision... ### NasalCrom **Generic:** cromolyn sodium (nasal) Findability: 78/100 | Insurance: $0–$30 | Cash: $6–$28 What Is NasalCrom? NasalCrom is the brand name for cromolyn sodium nasal spray, an over-the-counter (OTC) medication used to prevent and relieve nasal symptoms caused by allergies. Each spray delivers 5.2 mg of cromolyn sodium, the active ingredient, directly into the nasal passages. NasalCrom belongs to the mast cell stabilizer class — the only OTC nasal spray in this drug category. It is approved for adults and children age 2 and older and is sold without a prescription at most major... ### Natacyn **Generic:** Natacyn Findability: 45/100 | Shortage: active | Insurance: $30–$150 | Cash: $400–$700 What Is Natacyn? Natacyn (Natamycin) is a polyene antifungal antibiotic formulated as an ophthalmic suspension. It is the only FDA-approved topical antifungal eye medication in the United States. Natacyn is prescribed to treat serious fungal infections of the eye, including fungal keratitis (corneal infection, especially caused by Fusarium solani), fungal blepharitis (eyelid infection), and fungal conjunctivitis. It may also be used off-label for fungal endophthalmitis and infections caused by... ### Natesto **Generic:** testosterone nasal gel Findability: 45/100 | Insurance: $0–$100 | Cash: $140–$1,047 What Is Natesto? Natesto is the only FDA-approved intranasal testosterone replacement therapy in the United States. Approved in 2014 and manufactured by Acerus Pharmaceuticals Corporation, it is a metered-dose nasal gel that delivers testosterone directly through the nasal mucosa into the bloodstream. Natesto is prescribed to adult males with hypogonadism — a medical condition in which the body fails to produce sufficient testosterone. This can result from problems with the testicles (primary... ### Natroba **Generic:** spinosad Findability: 52/100 | Insurance: $0–$50 | Cash: $121–$402 What Is Natroba? Natroba is a prescription topical suspension containing spinosad 0.9% in a 120 mL bottle. It is manufactured by ParaPRO LLC / Cipher Pharmaceuticals and was first approved by the FDA in 2011. Natroba is used to treat head lice infestations (pediculosis capitis) in adults and children 6 months and older, and scabies infestations in adults and children 4 years and older (additional FDA approval in 2021). The active ingredient, spinosad, is derived from a naturally occurring... ### Neffy **Generic:** Neffy Findability: 55/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $685–$800 What Is Neffy? Neffy is the first and only needle-free epinephrine nasal spray approved for the emergency treatment of Type I allergic reactions, including anaphylaxis, in adults and children aged 4 years and older weighing 33 lbs (15 kg) or greater. Made by ARS Pharmaceuticals, Neffy delivers epinephrine through a simple nasal spray, eliminating the need for an intramuscular injection. This makes it an important option for patients who have needle phobia or caregivers who may hesitate to... ### Nemluvio **Generic:** nemolizumab Findability: 65/100 | Insurance: $0–$15,000/yr savings | Cash: $4,356–$6,144/pen What Is Nemluvio? Nemluvio (nemolizumab-ilto) is a prescription biologic medication manufactured by Galderma Laboratories. It is the brand name for nemolizumab, a humanized IgG2 monoclonal antibody that targets the interleukin-31 receptor alpha (IL-31RA). The FDA first approved Nemluvio on August 12, 2024 for prurigo nodularis (PN) in adults, then expanded approval in December 2024 to include moderate-to-severe atopic dermatitis (eczema) in adults and patients aged 12 and older. The FDA... ### Nepafenac **Generic:** nepafenac Findability: 72/100 | Insurance: $60–$80 | Cash: $321–$481 What Is Nepafenac? Nepafenac is a prescription ophthalmic NSAID (nonsteroidal anti-inflammatory drug) used to treat pain and inflammation associated with cataract surgery. It is available as Nevanac (0.1% suspension) and Ilevro (0.3% suspension), both manufactured by Harrow Eye. Nepafenac is a prodrug — it is converted to its active form (amfenac) inside the eye after topical application. FDA-approved since 2005 (Nevanac) and 2012 (Ilevro), nepafenac is used for a short, defined course:... ### Neupro **Generic:** rotigotine Findability: 55/100 | Insurance: $0–$190 | Cash: $873–$1,095 What Is Neupro? Neupro (rotigotine transdermal system) is a once-daily prescription patch that delivers rotigotine — a non-ergoline dopamine agonist — continuously through the skin over 24 hours. It was first approved by the FDA in 2007 and is manufactured by UCB, Inc. As of 2026, Neupro is the only FDA-approved transdermal dopamine agonist patch in the United States. Neupro is FDA-approved for two conditions: Parkinson's disease (both early-stage as monotherapy and advanced-stage in... ### Nevanac **Generic:** nepafenac Findability: 72/100 | Insurance: $60–$80 | Cash: $329–$413 What Is Nevanac? Nevanac is the brand name for nepafenac 0.1% ophthalmic suspension — a sterile, prescription eye drop used before and after cataract surgery. It belongs to the class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). Nevanac was FDA-approved on August 19, 2005, and is currently distributed by Harrow Eye. Nevanac is FDA-approved for the treatment of pain and inflammation associated with cataract surgery in patients 10 years of age and older. The standard... ### Nevirapine **Generic:** nevirapine Findability: 82/100 | Insurance: $0–$20 | Cash: $19–$90 What Is Nevirapine? Nevirapine is an FDA-approved antiretroviral medication used to treat HIV-1 (human immunodeficiency virus type 1) infection. It belongs to the non-nucleoside reverse transcriptase inhibitor (NNRTI) drug class. First approved in 1996, nevirapine was one of the first NNRTI medications available and played a pivotal role in expanding HIV treatment options worldwide. Originally sold as Viramune (immediate-release) and Viramune XR (extended-release) by Boehringer Ingelheim,... ### Nexlizet **Generic:** bempedoic acid and ezetimibe Findability: 72/100 | Insurance: $10–$60 | Cash: $231–$595 What Is Nexlizet? Nexlizet is a brand-name prescription oral tablet manufactured by Esperion Therapeutics, containing two active ingredients: bempedoic acid (180 mg) and ezetimibe (10 mg). It was first FDA-approved on February 26, 2020 — the first non-statin, fixed-dose combination cholesterol-lowering pill ever approved in the United States. Nexlizet is indicated to reduce LDL ("bad") cholesterol in adults with primary hyperlipidemia, including heterozygous familial hypercholesterolemia... ### Nextstellis 28 Day **Generic:** drospirenone and estetrol Findability: 68/100 | Insurance: $0–$50 | Cash: $65–$303 What Is Nextstellis 28 Day? Nextstellis 28 Day is a combination oral contraceptive pill approved by the FDA in April 2021. It is manufactured by Mayne Pharma and contains two active ingredients: drospirenone (3 mg), a synthetic progestin, and estetrol (14.2 mg), a novel synthetic estrogen derived from plant sources. Estetrol (E4) is the first new contraceptive estrogen approved in the United States in over 50 years. Unlike the ethinyl estradiol found in most other oral contraceptives,... ### NicoDerm CQ **Generic:** nicotine transdermal Findability: 85/100 | Insurance: $0–$30 | Cash: $20–$100 What Is NicoDerm CQ? NicoDerm CQ is the brand name for a nicotine transdermal patch — an over-the-counter (OTC) smoking cessation aid manufactured by Haleon (formerly GlaxoSmithKline Consumer Healthcare). It is classified as a nicotine replacement therapy (NRT) and is FDA-approved to help adults quit smoking by reducing nicotine withdrawal symptoms and cravings. NicoDerm CQ comes in three strengths — 7 mg, 14 mg, and 21 mg per 24 hours — designed to be used in a structured 3-step tapering... ### Nimodipine **Generic:** nimodipine Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $28–$1,555 What Is Nimodipine? Nimodipine is a prescription calcium channel blocker (dihydropyridine class) that is FDA-approved for improving neurological outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH). It is the only FDA-approved oral treatment for preventing vasospasm-related brain damage after a ruptured intracranial aneurysm. The FDA first approved nimodipine in 1988. It is sold under the brand name Nymalize (an oral solution) and is also available as generic nimodipine 30 mg... ### Ninjacof XG **Generic:** codeine phosphate/guaifenesin Findability: 55/100 | Insurance: $0–$30 | Cash: $15–$60 What Is Ninjacof XG? Ninjacof XG is a brand-name prescription oral liquid manufactured by Centurion Labs, LLC (Birmingham, AL). Each 5 mL teaspoon contains codeine phosphate 8 mg — an opioid cough suppressant — and guaifenesin 200 mg, an expectorant that thins and loosens mucus in the airways. The solution has a cotton candy flavor and is dispensed in 16 fl oz (473 mL) bottles. Ninjacof XG is classified as a Schedule V controlled substance under the DEA Controlled Substances Act. It requires... ### Nitazoxanide **Generic:** nitazoxanide Findability: 55/100 | Insurance: $0–$30 | Cash: $223–$1,113 What Is Nitazoxanide? Nitazoxanide is an FDA-approved antiparasitic medication belonging to the thiazolide drug class. It is sold under the brand name Alinia, with FDA-approved generic tablets available since 2020. It is prescribed for the treatment of diarrhea caused by two common intestinal parasites: Giardia lamblia (giardiasis) and Cryptosporidium parvum (cryptosporidiosis) in immunocompetent patients. Nitazoxanide is approved for adults and children 1 year of age and older. Adults and... ### Nitro-Dur **Generic:** nitroglycerin transdermal Findability: 68/100 | Insurance: $0–$20 | Cash: $20–$200 What Is Nitro-Dur? Nitro-Dur is the brand name for nitroglycerin transdermal patches — a skin patch applied once daily to prevent chest pain (angina) in people with coronary artery disease. The patch releases nitroglycerin steadily into the bloodstream over 12 to 14 hours, providing continuous angina prevention without multiple daily doses. Nitroglycerin is an organic nitrate and vasodilator — one of the oldest and most established cardiac medications. It's available in multiple forms... ### Nitrofurantoin **Generic:** Nitrofurantoin Findability: 72/100 | Insurance: $0–$15 | Cash: $5–$45 What Is Nitrofurantoin? Nitrofurantoin is a nitrofuran antibiotic used specifically to treat and prevent uncomplicated lower urinary tract infections (UTIs), also known as acute cystitis. It has been a trusted UTI treatment for decades and is considered a first-line option by major clinical guidelines. Nitrofurantoin is available as brand-name Macrobid, Macrodantin, and Furadantin, as well as affordable generic versions. It is only effective for lower urinary tract infections and should not be... ### Nitroglycerin **Generic:** Nitroglycerin Findability: 58/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $15–$90 What Is Nitroglycerin? Nitroglycerin is an organic nitrate vasodilator that has been a cornerstone of cardiovascular medicine for over a century. It is primarily used for the acute relief and prevention of angina pectoris (chest pain caused by coronary artery disease). The sublingual tablet form is the classic "heart pill" that patients place under the tongue at the first sign of chest pain. Beyond angina, Nitroglycerin is also used in hospital settings for acute heart failure, perioperative... ### Nitrostat **Generic:** nitroglycerin Findability: 78/100 | Insurance: $0–$20 | Cash: $9–$80 What Is Nitrostat? Nitrostat is the brand name for nitroglycerin sublingual tablets — small, fast-dissolving tablets placed under the tongue or inside the cheek. The active ingredient is nitroglycerin (also called glyceryl trinitrate), an organic nitrate that has been used in cardiovascular medicine for over a century. It is manufactured by Pfizer, and FDA-approved generic versions are widely available. Nitrostat is FDA-approved for the acute relief and prophylaxis of angina pectoris — chest... ### Nivestym **Generic:** filgrastim-aafi Findability: 68/100 | Insurance: $0–$50 | Cash: $222–$445+ What Is Nivestym? Nivestym (filgrastim-aafi) is an FDA-approved biosimilar to Neupogen (filgrastim), manufactured by Pfizer and approved on July 20, 2018. It belongs to the granulocyte colony-stimulating factor (G-CSF) class of medications — biologics that stimulate the bone marrow to produce more neutrophils, the white blood cells that fight bacterial and fungal infections. Nivestym is most commonly prescribed for patients undergoing cancer chemotherapy to prevent febrile neutropenia — a... ### Nizatidine **Generic:** nizatidine Findability: 78/100 | Insurance: $0–$30 | Cash: $38–$193 What Is Nizatidine? Nizatidine is a prescription H2 receptor antagonist (H2 blocker) that reduces the amount of acid produced by the stomach. It was originally developed by Eli Lilly and marketed under the brand name Axid, which received FDA approval in April 1988. The brand has since been discontinued; only generic nizatidine is available today. Nizatidine comes as 150 mg and 300 mg oral capsules and is used to treat active duodenal and gastric ulcers, gastroesophageal reflux disease (GERD),... ### Nonoxynol-9 **Generic:** nonoxynol-9 Findability: 88/100 | Insurance: $0–$20 | Cash: $8–$25 What Is Nonoxynol-9? Nonoxynol-9 (abbreviated N-9) is a nonionic surfactant used as the active ingredient in most over-the-counter vaginal spermicide products in the United States. It has been in use as a contraceptive agent for more than 60 years and is the only FDA-approved OTC spermicidal ingredient available in the US market. It is available under several brand names including VCF (Vaginal Contraceptive Film and Gel), Encare, Conceptrol, Gynol II, and the Today Sponge. All of these... ### Norgesic **Generic:** orphenadrine-aspirin-caffeine Findability: 35/100 | Insurance: $0–$150 | Cash: $30–$1,413 What Is Norgesic? Norgesic is a brand-name prescription tablet that combines three active ingredients: orphenadrine citrate (25 mg), aspirin (385 mg), and caffeine (30 mg). Manufactured by Galt Pharmaceuticals, it is classified as a multimodal, opioid-free pain reliever for mild to moderate acute musculoskeletal pain. Norgesic is FDA-approved for symptomatic relief of pain from acute musculoskeletal disorders including muscle strains, sprains, and overuse injuries. It is used alongside rest... ### Norgestrel **Generic:** norgestrel Findability: 88/100 | Insurance: $0–$20 | Cash: $15–$20 What Is Norgestrel? Norgestrel is a synthetic progestin used as a daily oral contraceptive to prevent pregnancy. It is sold under the brand name Opill — the first FDA-approved over-the-counter daily birth control pill in the United States. Norgestrel has been approved for prescription use since 1973, giving it over 50 years of clinical use and an extensive safety record. In July 2023, the FDA approved it for OTC sale, and it became available on pharmacy shelves nationwide in March 2024. As a... ### Nortrel 1/35 21 Day **Generic:** norethindrone/ethinyl estradiol Findability: 78/100 | Insurance: $0–$30 | Cash: $20–$80 What Is Nortrel 1/35 21 Day? Nortrel 1/35 21 Day is a combination oral contraceptive (birth control pill) manufactured by Teva Pharmaceuticals USA. Each active yellow tablet contains norethindrone 1 mg (a synthetic progestin) and ethinyl estradiol 0.035 mg (a synthetic estrogen). The "21 Day" format means the pack contains 21 active hormone tablets with no placebo pills — patients take one tablet daily for 21 days, followed by a 7-day pill-free interval. Nortrel 1/35 is a monophasic pill,... ### Nortriptyline **Generic:** nortriptyline Findability: 88/100 | Insurance: $0–$10 | Cash: $4–$42 What Is Nortriptyline? Nortriptyline is a tricyclic antidepressant (TCA) that has been used clinically since 1963. It is sold under the brand name Pamelor in the United States and is widely available as a generic from multiple manufacturers. The medication is FDA-approved for the treatment of depression in adults. It is also frequently prescribed off-label for neuropathic pain, postherpetic neuralgia, diabetic neuropathy, migraine prevention, smoking cessation, and ADHD in... ### Novarel **Generic:** Novarel Findability: 35/100 | Shortage: active | Insurance: $30–$100 | Cash: $150–$500 What Is Novarel? Novarel is a brand-name injectable form of human chorionic gonadotropin (hCG), a hormone naturally produced by the placenta during pregnancy. It is manufactured by Ferring Pharmaceuticals and belongs to the gonadotropin drug class. Novarel is FDA-approved for: Induction of ovulation in anovulatory infertile women who have been pretreated with human menotropins Prepubertal cryptorchidism (undescended testicles) not caused by anatomic obstruction Hypogonadotropic... ### NovoEight **Generic:** turoctocog alfa Findability: 62/100 | Insurance: $0–$30+ copay | Cash: Variable (specialty) What Is NovoEight? NovoEight (turoctocog alfa) is a recombinant antihemophilic factor VIII (FVIII) manufactured by Novo Nordisk and FDA-approved in October 2013. It is indicated for use in adults and children with hemophilia A — a rare genetic bleeding disorder caused by a deficiency of clotting factor VIII. NovoEight replaces the missing FVIII, temporarily restoring the blood's ability to clot normally. NovoEight is approved for three clinical uses: on-demand treatment and control of... ### Novolin N **Generic:** insulin isophane human Findability: 80/100 | Insurance: $0–$35 | Cash: $25–$136 What Is Novolin N? Novolin N is the brand name for insulin isophane human, commonly known as NPH (Neutral Protamine Hagedorn) insulin. Manufactured by Novo Nordisk, it is an intermediate-acting human insulin used to improve blood sugar control in adults and children with diabetes mellitus, including type 1 and type 2 diabetes. Novolin N is a white, cloudy suspension that must be gently mixed before each injection. It is available as a 10 mL vial (U-100, 100 units/mL) and a 3 mL FlexPen... ### Nuedexta **Generic:** dextromethorphan / quinidine Findability: 72/100 | Insurance: $20–$75 | Cash: $1,500–$1,600 What Is Nuedexta? Nuedexta is a prescription combination capsule containing dextromethorphan hydrobromide (20 mg) and quinidine sulfate (10 mg). It was developed by Avanir Pharmaceuticals (a subsidiary of Otsuka) and received FDA approval in October 2010. Nuedexta is the only FDA-approved medication specifically indicated for pseudobulbar affect (PBA). PBA is a neurological condition characterized by sudden, involuntary, and frequent episodes of uncontrollable laughing and/or crying that are... ### Nurtec ODT **Generic:** rimegepant Findability: 72/100 | Insurance: $0–$50 | Cash: $1,075–$1,415 What Is Nurtec ODT? Nurtec ODT is the brand name for rimegepant, a prescription migraine medication approved by the FDA in February 2020 for acute treatment and May 2021 for prevention of episodic migraine in adults. It is the first and only oral medication approved by the FDA for both the acute treatment and preventive treatment of migraine. Nurtec ODT belongs to a drug class called CGRP receptor antagonists, also known as "gepants." It is formulated as an orally disintegrating tablet (ODT)... ### Nusinersen **Generic:** nusinersen Findability: 72/100 | Insurance: Varies by plan | Cash: $125,000/injection What Is Nusinersen (Spinraza)? Nusinersen, marketed as Spinraza by Biogen, is the first FDA-approved disease-modifying therapy for spinal muscular atrophy (SMA). It received FDA approval in December 2016 and is now approved in more than 71 countries worldwide. Nusinersen is an antisense oligonucleotide (ASO) — a short, synthetic strand of genetic material — designed to treat SMA caused by mutations in the SMN1 gene. SMA affects approximately 1 in 10,000 newborns and is a leading genetic cause... ### NuvaRing **Generic:** etonogestrel/ethinyl estradiol Findability: 80/100 | Insurance: $0–$30 | Cash: $45–$238 What Is NuvaRing? NuvaRing (etonogestrel/ethinyl estradiol vaginal ring) is a prescription combination hormonal contraceptive used to prevent pregnancy in females of reproductive age. It is a flexible, transparent, latex-free ring that is inserted into the vagina for three weeks, then removed for one ring-free week before a new ring is inserted. Each NuvaRing contains 11.7 mg of etonogestrel (a progestin) and 2.7 mg of ethinyl estradiol (an estrogen), releasing 0.120 mg/day and 0.015 mg/day... ### Nuvigil **Generic:** armodafinil Findability: 65/100 | Insurance: $10–$50 | Cash: $30–$400 What Is Nuvigil (Armodafinil)? Nuvigil is the brand name for armodafinil, a wakefulness-promoting medication (eugeroic) approved by the FDA in June 2007. It is used to treat excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD). Armodafinil is the R-enantiomer — the purified, more pharmacologically active half — of racemic modafinil (Provigil). This gives it a slightly longer half-life and potentially longer duration of... ### Octreotide **Generic:** Octreotide Findability: 45/100 | Shortage: active | Insurance: $25–$100+ | Cash: $40–$8,500 What Is Octreotide? Octreotide is a synthetic analog of the natural hormone somatostatin. It is FDA-approved for the treatment of acromegaly (excess growth hormone), carcinoid syndrome (severe diarrhea and flushing from metastatic carcinoid tumors), and VIPomas (watery diarrhea from vasoactive intestinal peptide-secreting tumors). The oral capsule form, Mycapssa, is approved for long-term maintenance in acromegaly patients who have responded to injectable octreotide or lanreotide. Beyond its... ### Ofloxacin **Generic:** Ofloxacin Findability: 60/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $2–$60 What Is Ofloxacin? Ofloxacin is a fluoroquinolone antibiotic used to treat a wide range of bacterial infections. It is available in oral, ophthalmic (eye drop), and otic (ear drop) formulations. Common uses include urinary tract infections, respiratory infections, skin infections, bacterial conjunctivitis, corneal ulcers, otitis externa, and chronic suppurative otitis media. The brand names Floxin (oral/otic) and Ocuflox (ophthalmic) have been discontinued, but generic Ofloxacin remains... ### Ogsiveo **Generic:** nirogacestat Findability: 72/100 | Insurance: $0–$500+/mo | Cash: $25,000–$30,000/mo What Is Ogsiveo? Ogsiveo (nirogacestat) is a prescription medication that made history on November 27, 2023, when the FDA approved it as the first and only treatment specifically developed for adults with progressing desmoid tumors who require systemic treatment. Before Ogsiveo, there was no approved systemic therapy for this rare and often debilitating condition. Desmoid tumors are rare, locally aggressive soft tissue tumors arising from connective tissue. Although they are technically... ### Ohtuvayre **Generic:** ensifentrine Findability: 45/100 | Insurance: $0–$300/month | Cash: $2,950/month What Is Ohtuvayre? Ohtuvayre (ensifentrine) is a prescription inhaled medication used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adult patients. Developed by Verona Pharma, it received FDA approval on June 26, 2024, making it the first inhaled COPD maintenance drug with a novel mechanism of action in more than 20 years. Ohtuvayre is a first-in-class selective dual inhibitor of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) enzymes. It is... ### Olmesartan **Generic:** olmesartan medoxomil Findability: 78/100 | Insurance: $0–$30 | Cash: $10–$120 What Is Olmesartan? Olmesartan medoxomil (brand name Benicar) is a prescription medication used to treat high blood pressure (hypertension) in adults and children 6 years and older. It belongs to a class of drugs called angiotensin II receptor blockers (ARBs). Olmesartan received FDA approval in 2002 and has since become a widely used treatment for hypertension. It is available as a standalone tablet (5 mg, 20 mg, 40 mg) and in combination products: Benicar HCT (with hydrochlorothiazide),... ### Olumiant **Generic:** baricitinib Findability: 58/100 | Insurance: $5–$500+ | Cash: $2,500–$3,000 What Is Olumiant? Olumiant is the brand name for baricitinib, an oral Janus kinase (JAK) inhibitor developed by Incyte and marketed by Eli Lilly. It comes as a once-daily tablet in three strengths: 1 mg, 2 mg, and 4 mg. As of 2026, there is no FDA-approved generic version of baricitinib available in the United States. Olumiant is FDA-approved for three distinct conditions: moderately to severely active rheumatoid arthritis (RA) in adults who have had an inadequate response to TNF blockers... ### Omeprazole/Sodium Bicarbonate **Generic:** omeprazole/sodium bicarbonate Findability: 72/100 | Insurance: $0–$60 | Cash: $29–$100 What Is Omeprazole/Sodium Bicarbonate? Omeprazole/sodium bicarbonate is a prescription combination medication that pairs omeprazole — a proton pump inhibitor (PPI) — with sodium bicarbonate, an antacid. It is sold under the brand names Zegerid (capsules and powder for oral suspension) and Konvomep (oral suspension). An over-the-counter version, Zegerid OTC, is also available for frequent heartburn. FDA-approved indications include gastroesophageal reflux disease (GERD), active duodenal and... ### Omnitrope **Generic:** somatropin Findability: 68/100 | Insurance: $0–$200 | Cash: $656–$1,304 What Is Omnitrope? Omnitrope (somatropin) is a brand-name prescription growth hormone medication manufactured by Sandoz, a Novartis division. Its active ingredient is somatropin — a recombinant human growth hormone (rHGH) produced using E. coli bacteria through recombinant DNA technology. The resulting protein has 191 amino acids with an identical sequence to naturally occurring pituitary growth hormone. Omnitrope was one of the first FDA-approved growth hormone biosimilars when it received... ### Ondansetron **Generic:** Ondansetron Findability: 75/100 | Insurance: $0–$15 | Cash: $4–$50 What Is Ondansetron? Ondansetron is a prescription antiemetic medication used to prevent nausea and vomiting. It is FDA-approved for nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery (postoperative nausea and vomiting). It is also widely prescribed off-label for morning sickness during pregnancy, gastroenteritis, and cyclic vomiting syndrome. Originally marketed under the brand name Zofran by GlaxoSmithKline, Ondansetron is now available as an affordable generic... ### Onfi **Generic:** clobazam Findability: 42/100 | Shortage: active | Insurance: $0–$30 | Cash: $30–$150 What Is Onfi? Onfi is the brand name for clobazam, a 1,5-benzodiazepine anticonvulsant approved by the FDA in October 2011 for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients 2 years of age or older. LGS is a severe form of childhood-onset epilepsy characterized by multiple seizure types, cognitive impairment, and developmental delays. Onfi is an add-on treatment, meaning it is used alongside other anti-seizure medications, not as a standalone... ### Onyda XR **Generic:** clonidine hydrochloride Findability: 52/100 | Insurance: $25–$100 | Cash: $398–$525 What Is Onyda XR? Onyda XR (clonidine hydrochloride extended-release oral suspension) is a once-daily, non-stimulant ADHD medication approved by the FDA on May 24, 2024. It is the first and only liquid non-stimulant ADHD medication approved in the United States, and the only approved non-stimulant ADHD medication with nighttime dosing. Manufactured by Tris Pharma, Inc. using their proprietary LiquiXR® technology, Onyda XR is indicated for the treatment of ADHD as monotherapy or as adjunctive... ### Opill 28 Day **Generic:** norgestrel Findability: 82/100 | Insurance: $0–$20 | Cash: $15–$20 What Is Opill 28 Day? Opill 28 Day (norgestrel 0.075 mg) is the first FDA-approved over-the-counter daily oral contraceptive in the United States. Manufactured by Perrigo, it became available on pharmacy shelves nationwide in March 2024 after receiving FDA OTC approval on July 13, 2023. No prescription is required, and there is no age restriction to purchase it. Opill is a progestin-only pill (POP), sometimes called a minipill, because it contains only one hormone — norgestrel — with no... ### Orapred **Generic:** Orapred Findability: 5/100 | Shortage: active | Insurance: $0–$15/fill (generic w/ insurance) | Cash: $15–$50 (generic), $50–$500+ (brand) Orapred (Prednisolone Sodium Phosphate) is a liquid corticosteroid medication originally manufactured by Concordia Pharmaceuticals (formerly Shionogi). It is FDA-approved to treat a wide range of inflammatory and immune-related conditions, including: Asthma exacerbations Severe allergic reactions and allergic rhinitis Inflammatory conditions such as arthritis and dermatitis Autoimmune disorders including lupus and multiple sclerosis flares Nephrotic syndrome in children Croup in... ### Orgovyx **Generic:** relugolix Findability: 45/100 | Insurance: $10–$500 | Cash: $2,757–$2,945 What Is Orgovyx? Orgovyx is the brand name for relugolix, an oral prescription medication approved by the FDA on December 18, 2020 for the treatment of adult patients with advanced prostate cancer. It is manufactured by Sumitomo Pharma America in co-commercialization with Pfizer. Orgovyx is classified as a GnRH (gonadotropin-releasing hormone) receptor antagonist and is the first and only oral GnRH antagonist approved for prostate cancer in the United States. It belongs to the broader... ### Orphenadrine XR **Generic:** orphenadrine citrate Findability: 78/100 | Insurance: $0–$10 | Cash: $11–$50 What Is Orphenadrine XR? Orphenadrine XR (orphenadrine citrate extended-release) is a prescription skeletal muscle relaxant used to relieve discomfort associated with acute painful musculoskeletal conditions such as muscle strains, sprains, and acute back or neck pain. It was originally marketed under the brand name Norflex, which has since been discontinued. Only generic versions are available as of 2026, produced by multiple manufacturers including Amneal Pharmaceuticals and American Health... ### Ortho Tri-Cyclen 28 Day **Generic:** Ortho Tri-Cyclen 28 Day Findability: 85/100 | Insurance: $0–$10 | Cash: $6–$55 What Is Ortho Tri-Cyclen 28 Day? Ortho Tri-Cyclen 28 Day is a triphasic combination oral contraceptive containing norgestimate (a progestin) and ethinyl estradiol (an estrogen). It is FDA-approved for the prevention of pregnancy and for the treatment of moderate acne vulgaris in females at least 15 years old who have reached menarche. As a triphasic pill, the dose of norgestimate increases in three phases over the 21-day active cycle, while the estrogen dose stays constant. The pack includes... ### Os-Cal 500 With D **Generic:** calcium carbonate / cholecalciferol Findability: 82/100 | Insurance: $0–$15 | Cash: $7–$15 What Is Os-Cal 500 With D? Os-Cal 500 With D is a brand-name over-the-counter dietary supplement that combines two essential bone health nutrients: calcium carbonate (500 mg per tablet) and cholecalciferol, also known as Vitamin D3. It is manufactured by Haleon, the global consumer healthcare company spun off from GlaxoSmithKline in July 2022. Calcium carbonate is the most concentrated form of supplemental calcium, providing 40% elemental calcium by weight — meaning each 500 mg tablet... ### Oseltamivir **Generic:** Oseltamivir Findability: 55/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $25–$200 What Is Oseltamivir? Oseltamivir (brand name Tamiflu) is an antiviral medication used to treat and prevent influenza A and B. It belongs to a class of drugs called neuraminidase inhibitors. The FDA has approved oseltamivir for treating acute, uncomplicated flu in patients 2 weeks and older who have been symptomatic for no more than 48 hours, and for flu prevention (prophylaxis) in patients 1 year and older. It is also used off-label for avian influenza strains like H5N1 and H7N9. ### Otezla **Generic:** apremilast Findability: 65/100 | Insurance: $0–$150 | Cash: $5,000–$6,800 What Is Otezla? Otezla (apremilast) is an oral prescription medication manufactured by Amgen Inc. It is classified as a phosphodiesterase 4 (PDE4) inhibitor — a type of small-molecule drug that works inside immune cells to reduce inflammation. Otezla was first approved by the FDA in March 2014 and has since been used by over 650,000 patients worldwide. Otezla is FDA-approved for three conditions: plaque psoriasis (in adults and children ages 6+ weighing at least 20 kg), active psoriatic... ### Outgro Pain Relief **Generic:** benzocaine topical Findability: 35/100 | Shortage: active | Insurance: $0 | Cash: $10–$15 What Is Outgro Pain Relief? Outgro Pain Relief is an over-the-counter topical medication made by MedTech Products Inc. Its active ingredient is benzocaine 20% w/v — an ester-type local anesthetic that temporarily blocks nerve endings in the skin to reduce pain and itching. The product comes in a 0.31 fl oz (9.3 mL) bottle with a built-in brush applicator for easy application to the foot. Per its current FDA-compliant labeling, Outgro Pain Relief is indicated for the temporary relief of pain... ### Ovide **Generic:** malathion Findability: 45/100 | Insurance: $0–$50 | Cash: $76–$293 What Is Ovide? Ovide is the brand name for malathion 0.5% topical lotion, a prescription medication used to treat head lice (Pediculus humanus capitis) and their eggs (nits). It is an organophosphate pediculicide — a class of compounds that kills parasites by disrupting their nervous systems. Ovide was first FDA-approved in 1982, making it one of the longer-standing prescription lice treatments available. Ovide is available in a single formulation: a 0.5% topical lotion in a 59 mL (2 fl oz)... ### Oxandrolone **Generic:** oxandrolone Findability: 25/100 | Shortage: active | Insurance: $0 | Cash: $150–$350 What Is Oxandrolone? Oxandrolone is a synthetic anabolic steroid and androgen originally sold under the brand names Oxandrin and, historically, Anavar. It was first introduced for medical use in the United States in 1964. As a DEA Schedule III controlled substance, it requires a valid prescription from a licensed, DEA-registered prescriber. Oxandrolone was FDA-approved as adjunctive therapy to promote weight gain after weight loss following major surgery, chronic infection, or severe trauma;... ### Oxazepam **Generic:** oxazepam Findability: 55/100 | Insurance: $0–$30 | Cash: $14–$92 What Is Oxazepam? Oxazepam is a short-to-intermediate acting benzodiazepine approved by the FDA for the treatment of anxiety disorders, short-term relief of anxiety symptoms, anxiety associated with major depressive disorder, and alcohol withdrawal syndrome. It was first approved in 1964 and was marketed for decades under the brand name Serax, which has since been discontinued. Only generic Oxazepam is available in the United States today. Oxazepam is particularly valued in clinical settings... ### Oxcarbazepine **Generic:** oxcarbazepine Findability: 62/100 | Insurance: $0–$80 | Cash: $9–$104 What Is Oxcarbazepine? Oxcarbazepine is a prescription antiepileptic drug (AED) used to treat partial-onset (focal) seizures. It has been FDA-approved in the United States since 2000 and is available as a generic medication as well as under the brand names Trileptal (immediate-release) and Oxtellar XR (extended-release). It belongs to the dibenzazepine class of anticonvulsants and is structurally related to carbamazepine (Tegretol). Oxcarbazepine is FDA-approved as monotherapy for adults and... ### Oxtellar XR **Generic:** oxcarbazepine extended-release Findability: 72/100 | Insurance: $0–$100 | Cash: $233–$1,286 What Is Oxtellar XR? Oxtellar XR is a brand-name extended-release anticonvulsant medication containing oxcarbazepine, manufactured by Supernus Pharmaceuticals. It is FDA-approved as adjunctive (add-on) therapy for partial-onset seizures (also called focal seizures) in adults and children aged 6 years and older. Unlike its immediate-release counterpart Trileptal (oxcarbazepine IR), which is taken twice daily, Oxtellar XR uses matrix delivery technology to release oxcarbazepine gradually over... ### Oxybutynin **Generic:** oxybutynin Findability: 88/100 | Insurance: $0–$15 | Cash: $5–$57 What Is Oxybutynin? Oxybutynin is an FDA-approved prescription medication used to treat overactive bladder (OAB) — a condition characterized by sudden urges to urinate, urinary frequency, and urge incontinence. It is also used for neurogenic bladder conditions in adults and children. Brand names include Ditropan XL (extended-release oral tablet) and Oxytrol (transdermal patch, available over-the-counter for women). Oxybutynin has been on the market since the 1970s and is one of the most... ### Ozempic **Generic:** Ozempic Findability: 72/100 | Insurance: $25–$150 | Cash: $800–$1,100 What Is Ozempic? Ozempic (semaglutide) is a GLP-1 receptor agonist manufactured by Novo Nordisk. It is FDA-approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is also approved for the reduction of risk of major adverse cardiovascular events (cardiovascular death, nonfatal heart attack, nonfatal stroke) in adults with type 2 diabetes and established cardiovascular disease. Ozempic is administered as a once-weekly subcutaneous... ### Padcev **Generic:** enfortumab vedotin Findability: 72/100 | Insurance: $0–$5 per dose | Cash: $2,793–$4,185 per vial What Is Padcev? Padcev (enfortumab vedotin-ejfv) is a prescription antibody-drug conjugate (ADC) approved by the FDA for the treatment of locally advanced or metastatic urothelial cancer (bladder cancer and cancers of the urinary tract) as well as muscle-invasive bladder cancer (MIBC) in certain patients. It was developed by Astellas Pharma in collaboration with Pfizer and received its first FDA approval on December 18, 2019. Padcev is not a pill — it is administered intravenously (by IV... ### Palforzia 3 mg **Generic:** peanut allergen powder-dnfp Findability: 20/100 | Shortage: active | Insurance: $0–$200/mo | Cash: $654–$1,405/mo What Is Palforzia? Palforzia (peanut [Arachis hypogaea] allergen powder-dnfp) was the first and only FDA-approved oral immunotherapy (OIT) for peanut allergy. Approved in January 2020 for children ages 4 through 17 — and later expanded to toddlers ages 1 through 3 — it represented a landmark advancement in food allergy treatment. The drug is manufactured from defatted, roasted peanut flour and packaged in precisely measured capsules and sachets. The 3 mg dose refers to the starting level of... ### Pancreaze **Generic:** pancrelipase Findability: 65/100 | Insurance: $0–$60 | Cash: $93–$1,571 What Is Pancreaze? Pancreaze (pancrelipase) is an FDA-approved prescription pancreatic enzyme replacement therapy (PERT) used to treat exocrine pancreatic insufficiency (EPI) in adults and children, including infants. It was first approved by the FDA in April 2010 and is currently manufactured by VIVUS LLC. EPI is a condition in which the pancreas cannot produce sufficient digestive enzymes, leading to malabsorption of fats, proteins, and carbohydrates. Common causes include cystic fibrosis,... ### Pandel **Generic:** hydrocortisone probutate Findability: 60/100 | Insurance: $0–$150 | Cash: $170–$1,175 What Is Pandel? Pandel is a prescription-only topical cream containing hydrocortisone probutate 0.1% — a synthetic corticosteroid classified as medium potency. First approved by the FDA in 1997, it is used to reduce the inflammation and itching associated with a wide range of corticosteroid-responsive skin conditions in adults 18 and older. Pandel is manufactured and distributed by ANI Pharmaceuticals, Inc. and is supplied in 80-gram tubes. It is a brand-name-only product — no FDA-approved... ### Pantoprazole **Generic:** pantoprazole Findability: 82/100 | Insurance: $0–$30 | Cash: $9–$67 What Is Pantoprazole? Pantoprazole is a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach. Available generically and under the brand name Protonix, it is one of the most commonly prescribed medications in the United States, dispensed tens of millions of times each year. It is FDA-approved for the treatment and maintenance of erosive esophagitis associated with gastroesophageal reflux disease (GERD) in adults and children aged 5 years and older, as well as for... ### Paragard **Generic:** intrauterine copper contraceptive Findability: 72/100 | Insurance: $0–$30 | Cash: $1,167–$1,342 What Is Paragard? Paragard (intrauterine copper contraceptive, T 380A) is a T-shaped medical device inserted into the uterus by a healthcare provider to prevent pregnancy for up to 10 years. Manufactured by CooperSurgical, Inc., Paragard has been FDA-approved since 1984 and commercially available since 1988, making it one of the most well-established contraceptives in the United States. Unlike every other IUD available in the U.S. — Mirena, Liletta, Kyleena, and Skyla — Paragard contains... ### Paromomycin **Generic:** paromomycin Findability: 35/100 | Shortage: active | Insurance: $5–$100 | Cash: $2,000–$8,700 What Is Paromomycin? Paromomycin is an aminoglycoside antibiotic sold under the brand name Humatin (250 mg oral capsules), manufactured by Waylis Therapeutics. It is FDA-approved to treat intestinal amebiasis caused by Entamoeba histolytica and to serve as adjunctive therapy in the management of hepatic coma (hepatic encephalopathy). As of 2026, no generic version of paromomycin is commercially available in the United States — the only generic manufacturer, Avet Pharmaceuticals, discontinued... ### Paxil **Generic:** paroxetine Findability: 80/100 | Insurance: $0–$10 | Cash: $4–$87 What Is Paxil? Paxil is the brand name for paroxetine hydrochloride, a selective serotonin reuptake inhibitor (SSRI) antidepressant. Originally approved by the FDA in 1992 and developed by GlaxoSmithKline, Paxil is now primarily dispensed as generic paroxetine. It is used to treat a wide range of psychiatric conditions including depression, anxiety disorders, OCD, PTSD, PMDD, and menopausal symptoms. Available formulations include immediate-release (IR) tablets in 10 mg, 20 mg, 30 mg, and 40... ### Paxlovid **Generic:** Paxlovid Findability: 55/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $1,390 What Is Paxlovid? Paxlovid is a prescription oral antiviral medication for COVID-19, manufactured by Pfizer. It received FDA Emergency Use Authorization in December 2021 and full FDA approval in May 2023. Paxlovid is a combination of two medications packaged together: Nirmatrelvir — A protease inhibitor that blocks a key enzyme (Mpro/3CLpro) the SARS-CoV-2 virus needs to replicate Ritonavir — A pharmacokinetic booster that slows the breakdown of nirmatrelvir, keeping it active in the body... ### Paxlovid 5-Day **Generic:** Paxlovid 5-Day Findability: 55/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $1,400–$1,600 What Is Paxlovid 5-Day? Paxlovid 5-Day is an oral antiviral medication manufactured by Pfizer used to treat mild-to-moderate COVID-19 in adults who are at high risk for progressing to severe illness, hospitalization, or death. It is a combination of two medications — Nirmatrelvir and Ritonavir — co-packaged together. Treatment must be started within 5 days of COVID-19 symptom onset and is taken twice daily for a full 5-day course. ### Pegasys **Generic:** peginterferon alfa-2a Findability: 25/100 | Shortage: active | Insurance: $50–$500+ | Cash: $4,290–$4,500+ What Is Pegasys? Pegasys is the brand name for peginterferon alfa-2a, a pegylated alpha interferon used to treat serious viral and hematologic conditions. It is a modified form of recombinant human interferon alfa-2a, chemically modified with a polyethylene glycol (PEG) chain to extend its half-life to approximately 80 hours — allowing once-weekly dosing. Pegasys is FDA-approved for chronic hepatitis C (CHC) in adults and children 5 and older, and chronic hepatitis B (CHB) in adults and... ### Pentasa XR **Generic:** mesalamine Findability: 38/100 | Shortage: active | Insurance: $10–$150 | Cash: $43–$1,200 What Is Pentasa XR? Pentasa XR is the brand name for mesalamine extended-release (ER) capsules, manufactured by Takeda Pharmaceuticals. Mesalamine — also known as 5-aminosalicylic acid (5-ASA) — is an aminosalicylate anti-inflammatory drug used to treat ulcerative colitis (UC), an inflammatory bowel disease affecting the colon and rectum. The medication has been FDA-approved since 1987. Pentasa XR is available as 250 mg and 500 mg extended-release capsules. The standard dose for treating... ### Pentoxifylline XR **Generic:** pentoxifylline Findability: 78/100 | Insurance: $0–$30 | Cash: $15–$80 What Is Pentoxifylline XR? Pentoxifylline XR (extended-release pentoxifylline) is a prescription medication used primarily to reduce leg pain and cramping caused by insufficient blood flow during walking — a condition called intermittent claudication due to peripheral artery disease (PAD). It belongs to a drug class known as hemorheologic agents: medications that improve blood flow by altering the physical properties of blood. FDA-approved since 1984, pentoxifylline was originally sold under... ### Perforomist **Generic:** formoterol fumarate Findability: 45/100 | Insurance: $0–$100 | Cash: $92–$1,484 What Is Perforomist? Perforomist is the brand name for formoterol fumarate inhalation solution — a long-acting beta-2 adrenergic agonist (LABA) delivered through a standard jet nebulizer. It is FDA-approved for the long-term, twice-daily maintenance treatment of bronchoconstriction in adults with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Perforomist is available as 20 mcg/2 mL unit-dose vials. Each vial contains a sterile, clear, colorless... ### Peridex **Generic:** chlorhexidine gluconate Findability: 82/100 | Insurance: $0–$15 | Cash: $15–$40 What Is Peridex? Peridex is the brand name for chlorhexidine gluconate 0.12% oral rinse—a prescription-strength antiseptic mouthwash first approved by the FDA in August 1986. It is used to treat gingivitis, a condition marked by redness, swelling, and bleeding of the gums. Generic versions are widely available under names like chlorhexidine gluconate oral rinse, and other brands include PerioGard and Paroex. Peridex is used as part of a comprehensive gingivitis treatment plan alongside... ### Permethrin **Generic:** permethrin Findability: 65/100 | Insurance: $0–$30 | Cash: $10–$93 What Is Permethrin? Permethrin is a synthetic pyrethroid antiparasitic medication used topically to treat scabies and head lice. It is FDA-approved for the treatment of Sarcoptes scabiei (scabies) in the 5% cream formulation and pediculosis capitis (head lice) in the 1% lotion formulation. It is also used off-label for pubic lice. Permethrin is available as a prescription 5% cream (generics, formerly branded as Elimite and Acticin) and as an over-the-counter 1% lotion (brand: Nix). It is safe... ### Phenazopyridine **Generic:** phenazopyridine Findability: 85/100 | Insurance: $0–$15 | Cash: $2–$52 What Is Phenazopyridine? Phenazopyridine is a urinary tract analgesic—a medication specifically designed to relieve the pain, burning, urgency, and frequency caused by irritation of the lower urinary tract. It is classified as an azo dye compound and is available both by prescription (brand name Pyridium, 200 mg) and over the counter (AZO Urinary Pain Relief, Uristat, Uricalm, 95–99.5 mg tablets). In 2023, phenazopyridine was the 275th most prescribed medication in the United States, with... ### Phendimetrazine **Generic:** phendimetrazine Findability: 62/100 | Insurance: $15–$50 | Cash: $11–$140 What Is Phendimetrazine? Phendimetrazine is a prescription sympathomimetic amine anorectic used as a short-term adjunct to diet and exercise for the management of exogenous obesity in adults. It was formerly sold under the brand names Bontril PDM and Bontril Slow Release, both of which have been discontinued. Today, Phendimetrazine is available only as a generic medication. FDA-approved since 1976, Phendimetrazine is classified as a Schedule III controlled substance by the DEA. It is... ### Phenelzine **Generic:** phenelzine Findability: 55/100 | Shortage: active | Insurance: $0–$80 | Cash: $44–$163 What Is Phenelzine? Phenelzine (brand name Nardil) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) antidepressant that has been used in clinical psychiatry since the 1950s. It belongs to the hydrazine class of MAOIs and is one of the few non-selective, irreversible MAOIs still in widespread clinical use today. The FDA has approved phenelzine for the management of treatment-resistant depression (specifically atypical, nonendogenous, or neurotic depression), panic disorder,... ### Phenergan **Generic:** promethazine Findability: 42/100 | Shortage: active | Insurance: $0–$15 | Cash: $6–$30 What Is Phenergan (Promethazine)? Phenergan is the brand name for promethazine hydrochloride, a first-generation antihistamine and phenothiazine drug that has been available in the United States since 1951. While the original Phenergan brand has been discontinued, generic promethazine remains widely prescribed — with over 1 million prescriptions written in the US in 2023 alone. Promethazine is FDA-approved to treat nausea and vomiting (including post-operative nausea, motion sickness, and... ### Phenoxybenzamine **Generic:** phenoxybenzamine Findability: 30/100 | Insurance: $0–$100 | Cash: $599–$7,068 What Is Phenoxybenzamine? Phenoxybenzamine (brand name Dibenzyline) is a prescription medication used to control severe episodes of high blood pressure and excessive sweating caused by pheochromocytoma — a rare, usually benign tumor of the adrenal gland that secretes excess catecholamines (adrenaline and noradrenaline). It belongs to the class of non-selective, irreversible alpha-adrenergic blockers. Phenoxybenzamine's primary clinical role is preoperative preparation: it is used for 1 to 4... ### Phentermine **Generic:** Phentermine Findability: 75/100 | Insurance: $0–$30 | Cash: $10–$75 What Is Phentermine? Phentermine is a prescription appetite suppressant approved by the FDA for the short-term treatment of obesity. It belongs to a class of drugs called sympathomimetic amines and has been available since 1959, making it one of the oldest and most widely prescribed weight-loss medications in the United States. Phentermine is indicated for patients with a BMI of 30 or greater, or 27 or greater with at least one weight-related condition such as high blood pressure, type 2... ### Phentermine/Topiramate XR **Generic:** phentermine/topiramate xr Findability: 45/100 | Insurance: $0–$50 | Cash: $50–$200+ What Is Phentermine/Topiramate XR? Phentermine/topiramate extended-release (XR) — sold under the brand name Qsymia — is an FDA-approved once-daily oral capsule for chronic weight management. It combines two active ingredients: phentermine, a sympathomimetic amine appetite suppressant, and topiramate extended-release, an anticonvulsant that reduces cravings and increases satiety. The combination was FDA-approved for adults in July 2012 and expanded to adolescents ages 12 and older in 2022. It... ### Phenylephrine **Generic:** phenylephrine Findability: 55/100 | Shortage: active | Insurance: $0–$10 | Cash: $4–$15 What Is Phenylephrine? Phenylephrine is an over-the-counter sympathomimetic drug best known as the active ingredient in Sudafed PE. It belongs to the class of alpha-1 adrenergic agonists — drugs that mimic the effects of adrenaline on blood vessels, causing them to constrict (narrow). In the context of nasal congestion, this vasoconstriction is intended to reduce swelling in the nasal passages and improve airflow. Phenylephrine is found in dozens of OTC cold, cough, and allergy products,... ### Phenytoin XR **Generic:** Phenytoin XR Findability: 55/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $18–$120 What Is Phenytoin XR? Phenytoin XR (extended-release Phenytoin Sodium) is a hydantoin anticonvulsant medication used to treat and prevent seizures. It is FDA-approved for generalized tonic-clonic (grand mal) seizures, complex partial seizures, and the prevention and treatment of seizures during or following neurosurgery. Phenytoin XR is available as a generic and under the brand names Dilantin Kapseals and Phenytek. The typical dose ranges from 200 mg to 600 mg daily, most commonly 300 mg to... ### Phyrago **Generic:** dasatinib Findability: 55/100 | Insurance: $0–$500 | Cash: $4,000–$14,000 What Is Phyrago? Phyrago (dasatinib) is a prescription oral tablet used to treat Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) and Ph+ acute lymphoblastic leukemia (ALL). It is a BCR-ABL tyrosine kinase inhibitor (TKI) — a class of targeted cancer drugs that work by blocking the abnormal BCR-ABL protein produced by the Philadelphia chromosome, which drives uncontrolled leukemia cell growth. Phyrago was developed by Handa Therapeutics and commercially launched in the... ### Pimecrolimus **Generic:** pimecrolimus Findability: 78/100 | Insurance: $0–$60 | Cash: $70–$410 What Is Pimecrolimus? Pimecrolimus is a prescription topical cream used to treat mild to moderate atopic dermatitis (eczema). It belongs to the drug class known as topical calcineurin inhibitors (TCIs) — a non-steroidal class of anti-inflammatory medications that work by suppressing the local immune response in skin. Brand name: Elidel (manufactured for Bausch Health). Generic pimecrolimus 1% cream is also available from multiple manufacturers including Teva. The FDA approved pimecrolimus on... ### Pindolol **Generic:** Pindolol Findability: 30/100 | Shortage: active | Insurance: $5–$30 | Cash: $28–$225 What Is Pindolol? Pindolol is a nonselective beta-adrenergic blocker (beta blocker) approved by the FDA to treat hypertension (high blood pressure). It was originally marketed under the brand name Visken by Novartis (Sandoz), which has since been discontinued. Only generic versions are now available. In addition to its approved use for high blood pressure, Pindolol is sometimes prescribed off-label for angina prophylaxis, SSRI augmentation in major depressive disorder, and anxiety disorders.... ### Pitavastatin **Generic:** pitavastatin Findability: 82/100 | Insurance: $0–$50 | Cash: $36–$445 What Is Pitavastatin? Pitavastatin is a prescription cholesterol-lowering medication belonging to the statin class of drugs. It is sold under the brand names Livalo (pitavastatin calcium) and Zypitamag (pitavastatin magnesium), and is also available as a generic medication. The FDA first approved pitavastatin in 2009 under the brand name Livalo, manufactured by Kowa Pharmaceuticals America. Pitavastatin is FDA-approved to treat primary hyperlipidemia (high cholesterol) and mixed dyslipidemia... ### Plan B One-Step **Generic:** levonorgestrel Findability: 88/100 | Insurance: $0–$10 | Cash: $11–$50 What Is Plan B One-Step? Plan B One-Step is an over-the-counter emergency contraceptive pill — often called the morning-after pill — used to reduce the chance of pregnancy after unprotected sex or after another contraceptive method fails. It contains levonorgestrel 1.5 mg, a synthetic progestin that has been used in hormonal birth control for more than 35 years. Plan B One-Step is manufactured by Teva Pharmaceuticals and is available without a prescription or age restriction at most... ### Plaquenil **Generic:** hydroxychloroquine Findability: 65/100 | Insurance: $0–$30 | Cash: $15–$200 What Is Plaquenil? Plaquenil is the brand name for hydroxychloroquine sulfate, an oral medication that belongs to two drug classes: antimalarial quinolines and disease-modifying antirheumatic drugs (DMARDs). It comes as a 200 mg film-coated tablet and is taken by mouth, usually once or twice daily. Other brand names include Quineprox and Sovuna. Plaquenil is FDA-approved for systemic lupus erythematosus (SLE), discoid lupus erythematosus (DLE), rheumatoid arthritis (RA), and malaria... ### Plavix **Generic:** clopidogrel Findability: 92/100 | Insurance: $0–$15 | Cash: $4–$120 What Is Plavix (Clopidogrel)? Plavix is the brand name for clopidogrel bisulfate, an antiplatelet medication first approved by the FDA in 1997. Manufactured by Sanofi-Aventis, it is used to prevent dangerous blood clots in patients with cardiovascular disease. Generic clopidogrel became available in 2012 and is now one of the most commonly prescribed medications in the United States. Clopidogrel belongs to the thienopyridine class of P2Y12 platelet inhibitors. It is FDA-approved for... ### Polymyxin B/Trimethoprim **Generic:** polymyxin b trimethoprim Findability: 62/100 | Shortage: resolved | Insurance: $0–$15 | Cash: $12–$32 What Is Polymyxin B/Trimethoprim? Polymyxin B/Trimethoprim ophthalmic solution is a prescription antibiotic eye drop used to treat bacterial eye infections, including acute bacterial conjunctivitis (pink eye) and blepharoconjunctivitis. It is most commonly known by the brand name Polytrim. The FDA approved it in October 1988. The solution combines two antibiotics in a single sterile formulation: polymyxin B sulfate (10,000 units/mL), a polypeptide antibiotic targeting gram-negative bacteria,... ### Potaba **Generic:** potassium aminobenzoate Findability: 40/100 | Insurance: $15–$80 | Cash: $80–$150 What Is Potaba? Potaba is the brand name for potassium aminobenzoate (also written as potassium para-aminobenzoate or POTABA), a prescription antifibrotic medication derived from the vitamin B complex. It is the potassium salt of para-aminobenzoic acid (PABA) and has been used for decades to treat conditions characterized by abnormal fibrous tissue formation. Potaba is prescribed for fibrotic conditions including Peyronie's disease, scleroderma (systemic sclerosis), dermatomyositis, morphea,... ### Pradaxa **Generic:** Pradaxa Findability: 72/100 | Insurance: $10–$75 | Cash: $45–$530 What Is Pradaxa? Pradaxa (Dabigatran Etexilate Mesylate) is a prescription blood thinner classified as a direct thrombin inhibitor. It is manufactured by Boehringer Ingelheim Pharmaceuticals and is FDA-approved for several important uses: Reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation Treating deep vein thrombosis (DVT) and pulmonary embolism (PE) after initial parenteral anticoagulant therapy Reducing the risk of recurrence of DVT and... ### Praluent **Generic:** alirocumab Findability: 68/100 | Insurance: $35–$50 | Cash: $533–$777 What Is Praluent (Alirocumab)? Praluent (alirocumab) is a prescription injectable biologic medication used to lower LDL ("bad") cholesterol and reduce the risk of major cardiovascular events including heart attack and stroke. It belongs to a class of drugs called PCSK9 inhibitors — the most powerful LDL-lowering medications currently available, capable of reducing LDL-C by up to 63% on top of statin therapy. Praluent was the first PCSK9 inhibitor to receive FDA approval, cleared on July 24,... ### Pramoxine **Generic:** pramoxine Findability: 90/100 | Insurance: $0–$30 | Cash: $5–$157 What Is Pramoxine? Pramoxine (also known as pramocaine) is a topical anesthetic and antipruritic agent that has been FDA-approved since 1953. It is used to temporarily relieve pain and itching from a wide range of conditions including insect bites, minor burns and cuts, poison ivy rashes, hemorrhoids, and dry itchy skin. Pramoxine belongs to a unique chemical class — the morpholine ether anesthetics — distinct from both ester anesthetics (like benzocaine) and amide anesthetics (like... ### Pravastatin **Generic:** pravastatin Findability: 88/100 | Insurance: $0–$15 | Cash: $10–$30 What Is Pravastatin? Pravastatin is a prescription medication used to lower cholesterol and reduce the risk of cardiovascular events including heart attack and stroke. It belongs to the statin class of drugs (HMG-CoA reductase inhibitors), which are the most widely prescribed cholesterol-lowering medications in the world. Pravastatin was originally sold under the brand name Pravachol, but only generic versions are available in the United States today. Pravastatin is FDA-approved to treat... ### Prazosin **Generic:** prazosin Findability: 45/100 | Shortage: active | Insurance: $0–$15 | Cash: $10–$40 What Is Prazosin? Prazosin (brand name Minipress, largely discontinued) is a prescription medication classified as an alpha-1 adrenergic receptor antagonist. It was patented in 1965, received FDA approval for hypertension in 1974, and has been in continuous clinical use ever since. Prazosin is available as generic oral capsules in 1 mg, 2 mg, and 5 mg strengths. Prazosin has one FDA-approved indication—hypertension—and several well-established off-label uses: PTSD-associated nightmares and... ### Pred-G **Generic:** gentamicin / prednisolone ophthalmic Findability: 62/100 | Insurance: $15–$60 | Cash: $161–$190 What Is Pred-G? Pred-G is a brand-name prescription ophthalmic medication manufactured by Allergan (an AbbVie company). It combines two active ingredients — gentamicin sulfate 0.3% and prednisolone acetate 1% — in a single formulation designed to simultaneously treat bacterial eye infections and reduce ocular inflammation. It is available as an eye drop suspension (5 mL bottle) and as an ointment under the name Pred-G S.O.P. (3.5 g tube). Pred-G is FDA-approved for steroid-responsive... ### Pregabalin **Generic:** pregabalin Findability: 78/100 | Insurance: $0–$30 | Cash: $14–$330 What Is Pregabalin? Pregabalin (brand names Lyrica and Lyrica CR) is a prescription medication classified as a gamma-aminobutyric acid (GABA) analog and anticonvulsant. It was first approved by the FDA in December 2004 and is one of the most widely prescribed medications in the United States, used for a range of neurological pain conditions and epilepsy. The FDA has approved pregabalin for five conditions: diabetic peripheral neuropathy (nerve pain from diabetes), postherpetic neuralgia (pain... ### Premarin **Generic:** Premarin Findability: 65/100 | Shortage: monitoring | Insurance: $25–$75 | Cash: $215–$285 What Is Premarin? Premarin (Conjugated Estrogens) is a hormone replacement therapy (HRT) medication manufactured by Pfizer. It contains a mixture of conjugated estrogens derived from natural sources and is FDA-approved for treating moderate to severe menopausal symptoms including hot flashes and vaginal atrophy, prevention of postmenopausal osteoporosis, and treatment of hypoestrogenism due to various causes. Premarin is available as oral tablets, vaginal cream, and an injection form. It has... ### Prevalite **Generic:** cholestyramine Findability: 42/100 | Shortage: active | Insurance: $5–$25 | Cash: $30–$180 What Is Prevalite? Prevalite is the brand name for cholestyramine, a bile acid sequestrant medication used primarily to lower elevated LDL ("bad") cholesterol levels and to relieve itching caused by partial biliary obstruction. The Prevalite brand has been discontinued by its manufacturer; all cholestyramine currently on the market is available as a generic drug. Cholestyramine comes as a powder that is mixed with water, juice, or another liquid before drinking. Each dose contains 4 grams of... ### PreviDent **Generic:** sodium fluoride topical Findability: 72/100 | Insurance: $0–$20 | Cash: $11–$40 What Is PreviDent? PreviDent is a brand-name prescription dental product made by Colgate Oral Pharmaceuticals. Its active ingredient is sodium fluoride at 1.1% concentration — equivalent to 5,000 parts per million (ppm) of fluoride. This is approximately four to five times the fluoride concentration found in standard over-the-counter toothpaste (1,000–1,500 ppm), making it significantly more effective for patients at elevated risk of tooth decay. PreviDent comes in several formulations:... ### Prevymis **Generic:** letermovir Findability: 78/100 | Insurance: $0–$100+ | Cash: $7,700–$9,053 What Is Prevymis? Prevymis is the brand name for letermovir, an antiviral medication manufactured by Merck. First approved by the FDA on November 8, 2017, Prevymis belongs to a novel class of antivirals called CMV DNA terminase complex inhibitors — the first new class of CMV antivirals in decades. It works through a completely different mechanism than older antivirals like ganciclovir and valganciclovir. Prevymis is FDA-approved for the prophylaxis (prevention) of cytomegalovirus (CMV)... ### Primaquine **Generic:** primaquine phosphate Findability: 40/100 | Insurance: $0-$20 | Cash: $24-$60 What Is Primaquine? Primaquine phosphate is an 8-aminoquinoline antimalarial drug that has been FDA-approved since 1952. It is available only as a generic in the United States — there is no brand-name version. Each tablet contains 26.3 mg of primaquine phosphate, equivalent to 15 mg of the biologically active primaquine base. Primaquine's primary FDA-approved use is radical cure — preventing relapse — of Plasmodium vivax malaria. P. vivax creates dormant liver-stage parasites called... ### Primatene Mist **Generic:** epinephrine Findability: 82/100 | Insurance: $0–$20 | Cash: $29–$54 What Is Primatene Mist? Primatene Mist (epinephrine inhalation aerosol, 0.125 mg per actuation) is the only FDA-approved over-the-counter asthma inhaler available in the United States. It is manufactured by Amphastar Pharmaceuticals, Inc. and is approved for the temporary relief of mild symptoms of intermittent asthma — including wheezing, tightness of chest, and shortness of breath — in adults and children 12 years of age and older. The current version is a hydrofluoroalkane (HFA)-propelled... ### Primidone **Generic:** primidone Findability: 82/100 | Insurance: $0–$30 | Cash: $12–$36 What Is Primidone? Primidone (brand name Mysoline) is a first-generation barbiturate-type anticonvulsant medication first approved by the FDA on March 8, 1954. It is used to control seizures in people with epilepsy, including grand mal (tonic-clonic), psychomotor, and focal epileptic seizures. It is also widely used off-label as a first-line treatment for essential tremor — the most common movement disorder. Generic Primidone is available in 50 mg and 250 mg tablet forms and is manufactured... ### Pristiq XR **Generic:** Pristiq XR Findability: 75/100 | Insurance: $5–$30 | Cash: $18–$543 What Is Pristiq XR? Pristiq XR (Desvenlafaxine) is an extended-release antidepressant manufactured by Pfizer. It belongs to the serotonin-norepinephrine reuptake inhibitor (SNRI) class of medications and is FDA-approved for the treatment of major depressive disorder (MDD) in adults. Desvenlafaxine is the active metabolite of Venlafaxine (Effexor XR). It is also used off-label for generalized anxiety disorder, hot flashes associated with menopause, panic disorder, neuropathic pain, and... ### ProAir **Generic:** albuterol Findability: 72/100 | Shortage: active | Insurance: $0–$15 | Cash: $9–$50 What Is ProAir? ProAir is a brand name for albuterol sulfate, a short-acting beta agonist (SABA) bronchodilator used as a rescue inhaler for asthma and chronic obstructive pulmonary disease (COPD). It is one of the most widely prescribed medications in the United States, used by tens of millions of patients. ProAir is FDA-approved for the treatment or prevention of bronchospasm in patients 4 years of age and older with reversible obstructive airway disease, and for the prevention of... ### Procainamide **Generic:** procainamide Findability: 45/100 | Shortage: resolved | Insurance: $0–$50 | Cash: $100–$365 What Is Procainamide? Procainamide (procainamide hydrochloride) is a Class IA antiarrhythmic drug used to treat life-threatening cardiac arrhythmias. Originally approved by the FDA in 1950 and marketed as Pronestyl by Bristol-Myers Squibb, procainamide is one of the oldest antiarrhythmic medications still in clinical use today. It is classified under the Vaughan Williams system as a Class IA agent—a sodium channel blocker that also inhibits potassium channels. Procainamide is FDA-approved for... ### Proctofoam-Hc **Generic:** Proctofoam-Hc Findability: 55/100 | Shortage: monitoring | Insurance: $30–$75 | Cash: $190–$235 What Is Proctofoam-Hc? Proctofoam-Hc is a prescription aerosol foam used to treat pain, itching, swelling, and inflammation in the anal and perianal area. It contains two active ingredients: hydrocortisone acetate 1% (a corticosteroid) and pramoxine hydrochloride 1% (a local anesthetic). It is commonly prescribed for hemorrhoids, anal fissures, proctitis, and other anorectal conditions. Proctofoam-Hc is manufactured by Mylan Specialty L.P., a Viatris company. ### Proferrin **Generic:** heme iron polypeptide Findability: 72/100 | Insurance: $0 | Cash: $19–$85 What Is Proferrin? Proferrin is a brand name for heme iron polypeptide (HIP), an over-the-counter iron supplement derived from bovine (cow) hemoglobin. It is manufactured by Colorado Biolabs in Nebraska and is the only U.S.-based heme iron polypeptide supplement backed by clinical trial data. Proferrin comes in three formulations: Proferrin ES (10.5 mg heme iron polypeptide per tablet), Proferrin Forte (12 mg + 1 mg folic acid per capsule), and Proferrin Clear (10.5 mg in an NSF-certified,... ### Progesterone **Generic:** Progesterone Findability: 55/100 | Shortage: monitoring | Insurance: $5–$25 | Cash: $14–$422 What Is Progesterone? Progesterone is a naturally occurring steroid hormone classified as a progestin. It is used to prevent endometrial hyperplasia in postmenopausal women taking estrogen, treat secondary amenorrhea (absent periods), and support embryo implantation and early pregnancy in assisted reproductive technology (ART) procedures such as IVF. Progesterone is available in several forms including oral capsules (brand name Prometrium), vaginal gels (Crinone), vaginal inserts... ### Prolate **Generic:** oxycodone and acetaminophen Findability: 42/100 | Insurance: $5–$30 | Cash: $50–$4,500 What Is Prolate? Prolate is a brand-name prescription pain medication manufactured by Forte Bio-Pharma LLC. Each tablet combines two active pain-relieving ingredients: oxycodone hydrochloride (a powerful opioid analgesic) and acetaminophen (a non-opioid analgesic). Prolate is available in three strengths: 5mg/300mg, 7.5mg/300mg, and 10mg/300mg. Prolate is FDA-approved for the management of pain severe enough to require an opioid analgesic and for which alternative non-opioid treatments are... ### Prolia **Generic:** denosumab Findability: 78/100 | Insurance: $0–$50 | Cash: $1,891–$2,547 What Is Prolia (Denosumab)? Prolia is the brand name for denosumab, a human monoclonal antibody manufactured by Amgen Inc. and FDA-approved on June 1, 2010. It belongs to the drug class of RANKL inhibitors — biologic medications that reduce bone resorption by blocking a key signaling protein in the bone remodeling process. Prolia is given as a 60 mg subcutaneous injection once every six months at a healthcare provider's office. Prolia is FDA-approved for five indications: osteoporosis in... ### Promethazine **Generic:** promethazine Findability: 72/100 | Shortage: active | Insurance: $0–$15 | Cash: $5–$30 What Is Promethazine? Promethazine is a first-generation antihistamine and phenothiazine derivative with over 70 years of clinical use. Previously sold under the brand name Phenergan (now discontinued), it remains widely prescribed in generic form. Brand-name suppositories (Phenadoz and Promethegan) are still available. Promethazine is FDA-approved for allergic conditions (runny nose, hives, itching, allergic conjunctivitis), nausea and vomiting from motion sickness or surgery, motion... ### Prometrium **Generic:** Prometrium Findability: 60/100 | Shortage: monitoring | Insurance: $0–$30 | Cash: $12–$1,900 What Is Prometrium? Prometrium is a brand-name prescription medication containing micronized progesterone, a bioidentical form of the hormone progesterone that is chemically identical to what the body naturally produces. It is manufactured by Virtus Pharmaceuticals, LLC. Prometrium is FDA-approved for two primary uses: Prevention of endometrial hyperplasia in postmenopausal women receiving conjugated estrogens Treatment of secondary amenorrhea (absence of menstrual periods) It is also... ### Propafenone **Generic:** propafenone Findability: 78/100 | Insurance: $0–$30 | Cash: $16–$173 What Is Propafenone? Propafenone is a prescription antiarrhythmic medication used to treat and prevent serious heart rhythm disorders (arrhythmias). It is sold under the brand names Rythmol (immediate-release tablets) and Rythmol SR (extended-release capsules), with generic versions widely available. Propafenone was first approved by the FDA in November 1989 and belongs to the Class IC antiarrhythmic drug class — a category of sodium channel blockers. Propafenone is FDA-approved for three... ### Propranolol **Generic:** Propranolol Findability: 72/100 | Insurance: $0–$15 | Cash: $4–$45 What Is Propranolol? Propranolol is a non-selective beta-adrenergic blocker (beta-blocker) that has been used for decades to treat a wide range of cardiovascular and neurological conditions. It is FDA-approved for hypertension, angina, atrial fibrillation (rate control), secondary prevention after heart attack, migraine prophylaxis, essential tremor, and hypertrophic subaortic stenosis. It is also approved as Hemangeol for proliferating infantile hemangioma in infants. Propranolol is... ### Protopic **Generic:** tacrolimus topical Findability: 75/100 | Insurance: $0–$60 | Cash: $40–$300 What Is Protopic? Protopic is the brand name for tacrolimus ointment, a prescription topical medication used to treat moderate to severe atopic dermatitis (eczema). It belongs to a drug class called topical calcineurin inhibitors (TCIs) — a family of non-steroid medications that work by calming the overactive immune response responsible for eczema flares. Protopic is available in two strengths: 0.03% (approved for ages 2 and older, and preferred for sensitive areas) and 0.1% (approved for... ### Prozac **Generic:** fluoxetine Findability: 92/100 | Insurance: $0–$15 | Cash: $7–$25 What Is Prozac? Prozac is a brand name for fluoxetine hydrochloride, an antidepressant medication in the selective serotonin reuptake inhibitor (SSRI) class. Developed by Eli Lilly and Company and FDA-approved in December 1987, it was the first SSRI approved in the United States and remains one of the most prescribed antidepressants in history. Fluoxetine is FDA-approved to treat major depressive disorder (adults and children ≥8), obsessive-compulsive disorder (adults and children ≥7), panic... ### Prucalopride **Generic:** prucalopride Findability: 72/100 | Insurance: $0–$150 | Cash: $27–$735 What Is Prucalopride? Prucalopride (brand name Motegrity) is a prescription medication FDA-approved in December 2018 for the treatment of chronic idiopathic constipation (CIC) in adults. It belongs to a class of drugs called selective serotonin-4 (5-HT4) receptor agonists and works by stimulating colonic muscle contractions to promote regular bowel movements. Prucalopride was originally sold only under the brand name Motegrity by Takeda Pharmaceuticals. In January 2025, the FDA approved the... ### Pylera **Generic:** bismuth subcitrate potassium/metronidazole/tetracycline Findability: 62/100 | Insurance: $30–$100 | Cash: $187–$400 What Is Pylera? Pylera is a prescription oral capsule containing three active medications combined into one: bismuth subcitrate potassium (140 mg), metronidazole (125 mg), and tetracycline hydrochloride (125 mg). It is FDA-approved for the treatment of Helicobacter pylori (H. pylori) infection in adults with active duodenal ulcer disease or a history of duodenal ulcer within the past five years. Pylera is always used together with omeprazole (a proton pump inhibitor) as part of what is called... ### Pyridium **Generic:** phenazopyridine Findability: 88/100 | Insurance: $0–$15 | Cash: $5–$35 What Is Pyridium? Pyridium is the brand name for phenazopyridine hydrochloride, a urinary tract analgesic (pain reliever). It relieves the pain, burning, urgency, and frequency caused by irritation of the lower urinary tract — most commonly from a urinary tract infection (UTI). In 2023, phenazopyridine was the 275th most commonly prescribed medication in the United States, with more than 800,000 prescriptions written annually. Phenazopyridine is FDA-approved for the symptomatic relief of... ### Pyridostigmine **Generic:** pyridostigmine Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $25–$750 What Is Pyridostigmine? Pyridostigmine bromide is a cholinesterase inhibitor medication used primarily to treat myasthenia gravis (MG), a chronic autoimmune disorder that causes muscle weakness and fatigue. It is sold under the brand names Mestinon (immediate-release and extended-release tablets, oral solution) and Regonol (injectable form). Pyridostigmine has been in clinical use since 1955 and is on the World Health Organization's List of Essential Medicines. The medication is available in... ### Pyrilamine **Generic:** pyrilamine Findability: 82/100 | Insurance: $0–$20 | Cash: $5–$15 What Is Pyrilamine? Pyrilamine (also known as pyrilamine maleate or mepyramine) is a first-generation antihistamine belonging to the ethylenediamine class. It works by blocking histamine H1 receptors, reducing the cascade of allergy symptoms including runny nose, sneezing, itchy eyes, and hives. It has been in medical use since 1949 and remains a component in numerous OTC combination products. Pyrilamine is found in OTC menstrual relief products such as Midol Complete and Pamprin... ### Pyzchiva **Generic:** ustekinumab-ttwe Findability: 72/100 | Insurance: $0–$200 | Cash: $2,047–$4,147 What Is Pyzchiva? Pyzchiva (pronounced "piz-chi-va") is an FDA-approved biosimilar to Stelara (ustekinumab), one of the best-selling biologic medications in the world. The generic name for Pyzchiva is ustekinumab-ttwe. It was developed by Samsung Bioepis and is commercialized in the United States by Sandoz. Pyzchiva received FDA approval on June 28, 2024 and launched commercially in the US in February 2025. Pyzchiva is indicated for four conditions: moderate-to-severe plaque psoriasis (adults... ### Qbrelis **Generic:** Qbrelis Findability: 40/100 | Shortage: active | Insurance: $0–$50 | Cash: $690–$800 What Is Qbrelis? Qbrelis is a brand-name prescription medication containing Lisinopril in an oral solution form. It belongs to the angiotensin-converting enzyme (ACE) inhibitor drug class. Qbrelis is FDA-approved to treat hypertension (high blood pressure) in adults and children aged 6 and older, heart failure as adjunctive therapy, and to improve survival after a heart attack in hemodynamically stable patients. Originally approved by the FDA on April 29, 2016, Qbrelis was specifically... ### Qbrexza **Generic:** glycopyrronium Findability: 72/100 | Insurance: $0–$50 | Cash: $630–$939 What Is Qbrexza? Qbrexza (glycopyrronium cloth, 2.4%) is a prescription topical anticholinergic medication used to treat primary axillary hyperhidrosis — excessive underarm sweating — in adults and pediatric patients 9 years of age and older. It was the first FDA-approved topical product specifically indicated for this condition, approved in June 2018. Qbrexza comes as single-use, pre-moistened cloths packaged in individual pouches. Each cloth is applied once daily to both underarms using a... ### Qelbree **Generic:** Qelbree Findability: 45/100 | Shortage: active | Insurance: $20–$75 | Cash: $362–$525 What Is Qelbree? Qelbree (Viloxazine) is an FDA-approved, non-stimulant medication used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in adults and children ages 6 and older. It is manufactured by Supernus Pharmaceuticals. Unlike stimulant ADHD medications such as Adderall or Vyvanse, Qelbree works differently and is not a controlled substance, making it an attractive option for patients who cannot tolerate stimulants or prefer a non-controlled alternative. Qelbree is taken once... ### Qsymia **Generic:** phentermine/topiramate extended-release Findability: 45/100 | Insurance: $20–$60 | Cash: $63–$282 What Is Qsymia? Qsymia (phentermine and topiramate extended-release) is an FDA-approved prescription medication for chronic weight management. It is manufactured by VIVUS LLC and combines two active ingredients—phentermine, a Schedule IV controlled substance and sympathomimetic amine, and topiramate, an anticonvulsant medication—into a once-daily extended-release capsule taken in the morning. First approved by the FDA in July 2012, Qsymia is indicated for adults with obesity (BMI ≥30 kg/m²)... ### Quetiapine XR **Generic:** quetiapine xr Findability: 72/100 | Insurance: $0–$30 | Cash: $10–$65 What Is Quetiapine XR? Quetiapine XR (extended-release quetiapine fumarate) is a second-generation atypical antipsychotic sold under the brand name Seroquel XR by AstraZeneca, and available as generic quetiapine extended-release from multiple manufacturers. The "XR" designation refers to its extended-release delivery system, which allows for once-daily dosing compared to the twice-daily immediate-release formulation. Quetiapine XR is FDA-approved for schizophrenia in adults and adolescents... ### Quillichew ER **Generic:** Quillichew ER Findability: 45/100 | Shortage: active | Insurance: $20–$75 | Cash: $300–$450 What Is Quillichew ER? Quillichew ER is a cherry-flavored, extended-release chewable tablet containing methylphenidate hydrochloride. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. Quillichew ER is designed with approximately 30% immediate-release and 70% extended-release methylphenidate, providing both rapid onset and sustained symptom control throughout the day. It is manufactured by Tris Pharma and marketed by... ### Quillivant XR **Generic:** Quillivant XR Findability: 45/100 | Shortage: active | Insurance: $20–$75 | Cash: $328–$480 What Is Quillivant XR? Quillivant XR is a brand-name, extended-release liquid form of methylphenidate — one of the most widely prescribed medications for Attention Deficit Hyperactivity Disorder (ADHD). It is FDA-approved for patients aged 6 years and older. Unlike tablets or capsules, Quillivant XR is an oral suspension (liquid), making it an ideal option for children or adults who have difficulty swallowing pills. Quillivant XR is manufactured by Tris Pharma, Inc. and provides up to 12... ### Quinidine **Generic:** quinidine Findability: 68/100 | Insurance: $0–$30 | Cash: $30–$590 What Is Quinidine? Quinidine is one of the oldest antiarrhythmic medications in medicine, derived from the bark of the South American cinchona tree — the same plant that produces quinine. It has been used to treat abnormal heart rhythms since the early 20th century. Despite being largely replaced by newer antiarrhythmics for many indications, quinidine remains a critical medication for specific patient populations. Quinidine is classified as a Class IA antiarrhythmic under the Vaughan... ### Qulipta **Generic:** Qulipta Findability: 55/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $1,185–$1,600 What Is Qulipta? Qulipta (Atogepant) is a prescription oral medication manufactured by AbbVie used for the preventive treatment of episodic and chronic migraine in adults. It belongs to a class of drugs called CGRP receptor antagonists (gepants). Unlike injectable migraine preventives, Qulipta is taken as a once-daily tablet, making it a convenient option for patients who prefer oral medications. It was FDA-approved in September 2021 for episodic migraine and later expanded to include chronic... ### Quviviq **Generic:** Quviviq Findability: 55/100 | Shortage: monitoring | Insurance: $25–$150 | Cash: $550–$680 What Is Quviviq? Quviviq (Daridorexant) is a prescription medication approved by the FDA for the treatment of insomnia in adults who have difficulty falling asleep and/or staying asleep. It belongs to a class of drugs called dual orexin receptor antagonists (DORAs). Quviviq is manufactured by Idorsia Pharmaceuticals and is available as an oral tablet in 25 mg and 50 mg strengths. It is taken once nightly, within 30 minutes of going to bed, with at least 7 hours remaining before your planned... ### RIMSO-50 **Generic:** dimethyl sulfoxide Findability: 55/100 | Insurance: $0–$150 | Cash: $715–$878 What Is RIMSO-50? RIMSO-50 is the brand name for a sterile 50% dimethyl sulfoxide (DMSO) aqueous solution. FDA-approved since 1978, it holds the distinction of being the only FDA-approved bladder instillation therapy specifically indicated for interstitial cystitis (IC), also known as bladder pain syndrome (BPS). Interstitial cystitis is a chronic bladder condition characterized by persistent pain, pelvic pressure, and urinary urgency and frequency without evidence of bacterial infection.... ### RabAvert **Generic:** rabies vaccine (purified chick embryo cell) Findability: 45/100 | Insurance: $0–$100 | Cash: $393–$535 What Is RabAvert? RabAvert is the brand name for rabies vaccine (purified chick embryo cell vaccine, or PCECV), manufactured by Bavarian Nordic. It is one of only two FDA-approved human rabies vaccines available in the United States — the other being Imovax (human diploid cell vaccine, HDCV) by Sanofi Pasteur. RabAvert holds approximately 77% of the U.S. market share for human rabies vaccines as of 2025. RabAvert contains inactivated rabies virus (Flury LEP strain) grown in purified primary... ### Rabeprazole **Generic:** rabeprazole Findability: 80/100 | Insurance: $0–$30 | Cash: $15–$35 What Is Rabeprazole? Rabeprazole is a prescription medication that reduces the amount of acid your stomach produces. It belongs to a class of drugs called proton pump inhibitors (PPIs) and is sold under the brand name AcipHex — or as the pediatric formulation AcipHex Sprinkle for children ages 1–11. Generic rabeprazole is available from multiple manufacturers and is widely prescribed across primary care and gastroenterology settings. The FDA has approved rabeprazole for the treatment of... ### Rabies Immune Globulin, Human **Generic:** rabies immune globulin, human Findability: 72/100 | Insurance: $0–$300+ copay | Cash: $700–$1,500+ per vial What Is Rabies Immune Globulin, Human? Rabies immune globulin, human (HRIG) is a concentrated, plasma-derived biologic made from the blood of healthy human donors who have been hyperimmunized with rabies vaccine. It contains a high concentration of rabies virus neutralizing antibodies (RVNA) — standardized to at least 150 IU/mL (or 300 IU/mL for HyperRAB) — that provide immediate passive immunity against the rabies virus. HRIG is FDA-approved exclusively for post-exposure prophylaxis (PEP) of... ### Raldesy **Generic:** trazodone Findability: 60/100 | Insurance: $10–$50 | Cash: $389–$456 What Is Raldesy? Raldesy (trazodone hydrochloride oral solution, 10 mg/mL) is a brand-name prescription antidepressant manufactured by Validus Pharmaceuticals LLC. FDA-approved in 2024, it holds the distinction of being the first and only FDA-approved oral liquid formulation of trazodone in the United States. Raldesy is indicated for the treatment of major depressive disorder (MDD) in adults. It is not approved for use in pediatric patients. The liquid formulation was developed specifically... ### Relador **Generic:** lidocaine-prilocaine Findability: 55/100 | Shortage: active | Insurance: $0–$50 | Cash: $20–$1,529 What Is Relador? Relador is a brand-name topical anesthetic cream manufactured by Accelis Pharma. It contains two active ingredients: lidocaine 2.5% and prilocaine 2.5% — the same combination found in the original EMLA cream (AstraZeneca). Relador is classified as a branded-generic, meaning it uses the same well-established formulation as EMLA but is sold under the Relador trade name. Relador comes in two kit versions: Relador Pak (cream + Tegaderm occlusive dressing) and Relador Pak Plus... ### Relagard **Generic:** acetic acid / oxyquinoline Findability: 35/100 | Shortage: active | Insurance: $0–$40 | Cash: $43–$115 What Is Relagard? Relagard is a brand-name vaginal gel containing two active ingredients: glacial acetic acid (0.9%) and oxyquinoline (0.025%). It is classified as a topical anti-infective and is used to restore and maintain the natural acidic environment of the vagina, which has a healthy pH of approximately 3.8 to 4.3. Other brand names for the same formulation include Fem pH, Aci-Jel, Acid Jelly, and Acidic Vaginal Jelly. Relagard is prescribed as adjunctive therapy alongside antibiotics... ### Releuko **Generic:** filgrastim-ayow Findability: 55/100 | Insurance: $0–$200 | Cash: $490–$625 What Is Releuko? Releuko (filgrastim-ayow) is a biosimilar to Neupogen (filgrastim), a granulocyte colony-stimulating factor (G-CSF) medication used to stimulate the production of white blood cells (neutrophils) in the bone marrow. It was FDA-approved on February 25, 2022, developed by Kashiv Biosciences and marketed by Amneal Pharmaceuticals, making it the third filgrastim biosimilar available in the United States. Releuko is a recombinant human G-CSF protein produced through recombinant DNA... ### Relpax **Generic:** eletriptan Findability: 80/100 | Insurance: $0–$30 | Cash: $24–$575 What Is Relpax? Relpax is the brand name for eletriptan hydrobromide, a prescription migraine medication approved by the FDA in 2002. It belongs to the triptan drug class — a group of serotonin receptor agonists specifically designed to treat acute migraine attacks. Originally developed by Pfizer and distributed through its Roerig Division, Relpax has since gone off-patent and is now available as generic eletriptan hydrobromide from multiple manufacturers including Aurobindo Pharma. The drug... ### Resinol **Generic:** petrolatum and resorcinol topical Findability: 45/100 | Insurance: $0 | Cash: $10–$20 What Is Resinol? Resinol is an over-the-counter topical analgesic and skin protectant ointment manufactured by ResiCal, Inc. (NDC: 67492-105). Its active ingredients are Petrolatum 55% and Resorcinol 2%, with calamine, corn starch, lanolin, and zinc oxide as inactive ingredients. It has been used by patients, nurses, and physicians for over 125 years. Resinol is used to temporarily relieve pain and itching from minor skin irritations, minor burns, sunburn, minor cuts and scrapes, insect... ### Resmetirom **Generic:** resmetirom Findability: 72/100 | Insurance: $0–$500+/fill | Cash: $3,950–$4,116/mo What Is Resmetirom (Rezdiffra)? Resmetirom, sold under the brand name Rezdiffra, is the first FDA-approved pharmacologic treatment for noncirrhotic nonalcoholic steatohepatitis (NASH), now known as metabolic dysfunction-associated steatohepatitis (MASH), with moderate to advanced liver fibrosis. Manufactured by Madrigal Pharmaceuticals, resmetirom received FDA accelerated approval on March 14, 2024 — a historic milestone for a disease that had no approved medication for decades. Resmetirom is... ### Retacrit **Generic:** epoetin alfa-epbx Findability: 65/100 | Shortage: resolved | Insurance: $0–$150 | Cash: $228–$2,216 What Is Retacrit? Retacrit (epoetin alfa-epbx) is a biosimilar erythropoiesis-stimulating agent (ESA) approved by the FDA on May 15, 2018. It was the first biosimilar ESA approved in the United States and is manufactured by Hospira, a Pfizer company. Retacrit is biosimilar to Epogen and Procrit (both epoetin alfa) and has been shown to have no clinically meaningful differences from these reference products. Retacrit is FDA-approved to treat anemia due to chronic kidney disease (CKD) in... ### Retin-A **Generic:** tretinoin Findability: 72/100 | Insurance: $0–$30 | Cash: $28–$95 What Is Retin-A? Retin-A is a brand name for tretinoin, a topical retinoid derived from vitamin A (all-trans-retinoic acid). It was first approved by the FDA on October 20, 1971, making it one of the longest-standing prescription skincare medications available. Other brand names containing tretinoin include Retin-A Micro, Renova, Altreno, Atralin, Refissa, and Avita. Retin-A is FDA-approved for the topical treatment of acne vulgaris, and specific formulations (Renova, Refissa) are approved... ### Retre-Gel **Generic:** benzocaine Findability: 88/100 | Insurance: $0–$15 | Cash: $5–$30 What Is Retre-Gel? Retre-Gel is a brand-name topical anesthetic gel containing 20% benzocaine USP — the maximum available strength for topical use. It is formulated as a flavored, water-soluble gel designed to adhere to oral mucosal tissue and provide rapid surface-level numbing. Retre-Gel is primarily used in dental practice settings and is distributed through dental supply channels rather than retail pharmacy chains. Benzocaine, the active ingredient in Retre-Gel, belongs to the ester class... ### Revumenib **Generic:** Revumenib Findability: 35/100 | Shortage: active | Insurance: $0–$100/mo | Cash: $39,500/mo What Is Revumenib? Revumenib (sold under the brand name Revuforj) is a menin inhibitor used to treat certain types of acute leukemia. It was developed by Syndax Pharmaceuticals and received FDA approval in November 2024. Revumenib is specifically approved for: Treatment of relapsed or refractory acute leukemia with a KMT2A translocation in adult and pediatric patients 1 year and older Treatment of relapsed or refractory acute myeloid leukemia (AML) with a susceptible NPM1 mutation in... ### Rexulti **Generic:** Rexulti Findability: 62/100 | Shortage: monitoring | Insurance: $30–$100 | Cash: $1,200–$1,500 What Is Rexulti? Rexulti (Brexpiprazole) is an atypical antipsychotic medication manufactured by Otsuka Pharmaceutical in partnership with Lundbeck. It is FDA-approved for three indications: as an adjunctive treatment for major depressive disorder (MDD) in adults, for the treatment of schizophrenia in adults, and for the treatment of agitation associated with Alzheimer's dementia. Rexulti was first approved by the FDA in 2015 for MDD and schizophrenia, and received its Alzheimer's agitation... ### Reyvow **Generic:** Reyvow Findability: 25/100 | Shortage: active | Insurance: $0–$75 | Cash: $850–$1,100 What Is Reyvow and What Does It Do? Reyvow (Lasmiditan) is a prescription medication approved for the acute treatment of migraine with or without aura in adults. It belongs to a class of drugs called ditans, which work differently from triptans. Reyvow is taken as a single tablet at the onset of a migraine attack. It is a Schedule V controlled substance, meaning it has a low potential for misuse. Importantly, Eli Lilly has announced that Reyvow is being permanently discontinued, with U.S.... ### Rezdiffra **Generic:** Rezdiffra Findability: 35/100 | Shortage: active | Insurance: $0–$150 | Cash: $3,950–$4,116 What Is Rezdiffra? Rezdiffra (Resmetirom) is a first-in-class prescription medication approved by the FDA in March 2024 for the treatment of noncirrhotic nonalcoholic steatohepatitis (NASH), also known as metabolic dysfunction-associated steatohepatitis (MASH), in adults with moderate to advanced liver fibrosis (stages F2–F3). It is used in conjunction with diet and exercise. Rezdiffra is the first and only FDA-approved medication specifically for NASH/MASH, representing a major breakthrough... ### Rhinocort **Generic:** budesonide nasal spray Findability: 88/100 | Insurance: $0–$30 | Cash: $12–$20 What Is Rhinocort? Rhinocort is a brand name for budesonide nasal spray 32 mcg per spray. It is an intranasal corticosteroid (INC) — the most effective first-line treatment for allergic rhinitis according to current clinical guidelines. Rhinocort is available over the counter as Rhinocort Allergy and as a generic (budesonide nasal spray 32 mcg) at most major pharmacies and retailers without a prescription. The original prescription brand, Rhinocort Aqua, has been discontinued. The active... ### RhoGAM **Generic:** rho(d) immune globulin Findability: 30/100 | Shortage: active | Insurance: $0–$50 | Cash: $130–$250 What Is RhoGAM? RhoGAM is the brand name for Rho(D) immune globulin (human), a sterile biological medication made from human blood plasma. It contains concentrated IgG antibodies against the Rh(D) antigen — a protein found on red blood cells in most people. RhoGAM was first FDA-approved in 1968 and is manufactured by Kedrion Biopharma Inc. RhoGAM is most commonly given to Rh-negative pregnant patients to prevent Rh isoimmunization — a process by which the mother's immune system could... ### Rhofade **Generic:** oxymetazoline hydrochloride Findability: 75/100 | Insurance: $0–$60 | Cash: $45–$861 What Is Rhofade? Rhofade is the brand name for oxymetazoline hydrochloride cream, 1% — an FDA-approved topical treatment for persistent facial redness (erythema) associated with rosacea in adults. It was first approved by the FDA on January 18, 2017, and is currently commercialized by Mayne Pharma in the United States. Rhofade is classified as a topical alpha-1A adrenoceptor agonist. It is available as a white to off-white cream in a 30g laminated tube or airless pump bottle. As of 2026, no... ### Rifampin **Generic:** rifampin Findability: 62/100 | Shortage: active | Insurance: $0–$30 | Cash: $37–$184 What Is Rifampin? Rifampin (brand name Rifadin; also known internationally as rifampicin) is a prescription antibiotic in the rifamycin class. It is classified as an antimycobacterial agent and is FDA-approved to treat and prevent tuberculosis (TB), eliminate meningococcal bacteria from carriers, provide Haemophilus influenzae type B prophylaxis, and treat leprosy. It is also used off-label for MRSA infections and other bacterial conditions. Rifampin has been a cornerstone of global... ### Rifaximin **Generic:** Rifaximin Findability: 55/100 | Shortage: monitoring | Insurance: $30–$150 | Cash: $1,800–$2,400 What Is Rifaximin? Rifaximin is a non-absorbable rifamycin antibiotic that works locally in the gastrointestinal tract. It is sold under the brand name Xifaxan and is manufactured by Salix Pharmaceuticals (a Bausch Health company). Rifaximin is FDA-approved for three indications: treating travelers' diarrhea caused by noninvasive strains of E. coli in patients 12 and older, reducing the risk of overt hepatic encephalopathy recurrence in adults with liver disease, and treating irritable bowel... ### Rinvoq XR **Generic:** upadacitinib Findability: 45/100 | Insurance: $0–$100 | Cash: $6,500–$9,640 What Is Rinvoq XR? Rinvoq XR (upadacitinib) is a prescription oral medication manufactured by AbbVie. It belongs to the Janus kinase (JAK) inhibitor drug class — specifically, it is a second-generation selective JAK1 inhibitor. Available as extended-release tablets in 15 mg, 30 mg, and 45 mg strengths, Rinvoq XR is taken once daily by mouth, with or without food. First approved by the FDA in August 2019 for rheumatoid arthritis, Rinvoq XR has since expanded to nine approved indications... ### Risankizumab **Generic:** risankizumab Findability: 40/100 | Insurance: $0–$100/dose | Cash: $22,000–$23,000/dose What Is Risankizumab (Skyrizi)? Risankizumab (brand name Skyrizi) is a prescription biologic medication made by AbbVie. It is a humanized monoclonal IgG1 antibody classified as an interleukin-23 (IL-23) antagonist — specifically, it targets the p19 subunit of IL-23, blocking the inflammatory signaling responsible for several chronic autoimmune conditions. Skyrizi is FDA-approved for four conditions in adults: moderate to severe plaque psoriasis (April 2019), active psoriatic arthritis... ### Risperidone **Generic:** risperidone Findability: 84/100 | Insurance: $0–$15 | Cash: $7–$130 What Is Risperidone? Risperidone is an atypical (second-generation) antipsychotic medication first approved by the FDA in 1993. Originally sold under the brand name Risperdal by Janssen Pharmaceuticals, it has been widely available as a generic since the early 2000s. In 2023, risperidone was among the top 200 most prescribed medications in the United States, with over 2 million prescriptions. Risperidone is FDA-approved for three primary conditions: schizophrenia (in adults and adolescents... ### Ritalin **Generic:** Ritalin Findability: 45/100 | Shortage: active | Insurance: $10–$30 | Cash: $23–$52 What Is Ritalin? Ritalin (methylphenidate hydrochloride) is a prescription stimulant medication used to treat ADHD in children (ages 6+) and adults, and narcolepsy. First approved by the FDA in 1955, it remains one of the most commonly prescribed ADHD medications. Ritalin is manufactured by Sandoz (a Novartis division) and is available in both immediate-release (Ritalin) and extended-release (Ritalin LA) formulations. Generic methylphenidate is available from multiple... ### Ritalin LA **Generic:** Ritalin LA Findability: 40/100 | Shortage: active | Insurance: $10–$75 | Cash: $50–$350 What Is Ritalin LA? Ritalin LA (methylphenidate hydrochloride extended-release capsules) is a central nervous system (CNS) stimulant manufactured by Novartis Pharmaceuticals. It is FDA-approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. Ritalin LA uses SODAS (Spheroidal Oral Drug Absorption System) technology to deliver a bimodal release profile — 50% of the dose is released immediately and 50% is released approximately 4 hours... ### Rivastigmine **Generic:** rivastigmine Findability: 72/100 | Insurance: $10–$30 | Cash: $12–$424 What Is Rivastigmine? Rivastigmine is a prescription medication used to treat dementia associated with Alzheimer's disease and Parkinson's disease. It belongs to the drug class known as cholinesterase inhibitors. The brand name is Exelon — the oral capsule brand has been discontinued, but the Exelon Patch transdermal system remains available alongside multiple generic versions. Rivastigmine is FDA-approved for mild-to-moderate dementia in Alzheimer's disease and mild-to-moderate dementia... ### Rivelsa 91 Day **Generic:** levonorgestrel/ethinyl estradiol and ethinyl estradiol Findability: 75/100 | Insurance: $0–$30 | Cash: $67–$448 What Is Rivelsa 91 Day? Rivelsa 91 Day is an extended-cycle combination oral contraceptive (COC) manufactured by Teva Pharmaceuticals USA. It is the FDA-authorized generic version of Quartette. Each pack contains 91 tablets taken over a 13-week (91-day) cycle, giving patients approximately 4 scheduled periods per year instead of the standard 13. The medication contains two active hormones: levonorgestrel (a progestin, constant at 0.15 mg) and ethinyl estradiol (a synthetic estrogen that steps... ### Rizatriptan **Generic:** rizatriptan Findability: 88/100 | Insurance: $10–$30 | Cash: $7–$160 What Is Rizatriptan? Rizatriptan is a prescription medication used to treat acute migraine headaches with or without aura in adults and children ages 6 and older. It is sold under the brand names Rizatriptan is a prescription medication used to treat acute migraine headaches with or without aura in adults and children ages 6 and older. It is sold under the brand names Maxalt (standard tablet) and Maxalt-MLT (orally disintegrating tablet, or ODT). Generic versions of both forms are widely... ### Rocklatan **Generic:** netarsudil-latanoprost Findability: 55/100 | Insurance: $30–$100 | Cash: $345–$482 What Is Rocklatan? Rocklatan (netarsudil and latanoprost ophthalmic solution 0.02%/0.005%) is a prescription eye drop manufactured by Alcon and FDA-approved in March 2019. It is indicated for the reduction of elevated intraocular pressure (IOP) in adults with open-angle glaucoma or ocular hypertension. Rocklatan is the only FDA-approved fixed-dose combination of a Rho kinase (ROCK) inhibitor and a prostaglandin F2α analog. It combines two active ingredients — netarsudil 0.02% (previously... ### Ropinirole XR **Generic:** ropinirole Findability: 78/100 | Insurance: $0–$30 | Cash: $22–$87 What Is Ropinirole XR? Ropinirole XR (extended-release) is a once-daily prescription tablet used to treat the symptoms of Parkinson's disease. It belongs to a class of medications called non-ergoline dopamine agonists — drugs that directly activate dopamine receptors in the brain, mimicking the neurotransmitter dopamine that is deficient in Parkinson's disease. The brand-name version, Requip XL, was originally developed by GlaxoSmithKline and approved by the FDA in July 2008. In 2019, GSK... ### Roszet **Generic:** Roszet Findability: 55/100 | Shortage: monitoring | Insurance: $30–$75 | Cash: $150–$350 What Is Roszet? Roszet is a combination prescription medication containing Ezetimibe and Rosuvastatin in a single tablet. It is used to treat primary hyperlipidemia (high cholesterol) and homozygous familial hypercholesterolemia (HoFH). Roszet works by reducing LDL ("bad") cholesterol, total cholesterol, triglycerides, and ApoB while increasing HDL ("good") cholesterol. Roszet was FDA-approved in March 2021 and manufactured by Althera Life Sciences. The brand has since been discontinued, but... ### Rytary **Generic:** carbidopa and levodopa Findability: 55/100 | Insurance: $0–$100 | Cash: $330–$1,500 What Is Rytary? Rytary is the brand name for carbidopa and levodopa extended-release capsules, manufactured by Amneal Pharmaceuticals. It was approved by the FDA in January 2015 for the treatment of Parkinson's disease, post-encephalitic parkinsonism, and parkinsonism caused by carbon monoxide or manganese intoxication. You may also see it informally referred to as 'Rytary XR' or 'Rytary extended release,' but the official name is simply Rytary. Rytary contains two active ingredients:... ### SARS-CoV-2 Treatment **Generic:** nirmatrelvir/ritonavir Findability: 55/100 | Insurance: $0–$75 | Cash: $0–$1,820 What Are SARS-CoV-2 Antiviral Medications? SARS-CoV-2 antiviral medications are prescription drugs designed to fight the virus that causes COVID-19. They work by directly targeting viral replication — stopping the virus from making copies of itself inside your body. Unlike COVID-19 vaccines, which prevent infection, antivirals treat active infection after a positive test and must be started within five days of symptom onset to be effective. The primary antiviral medications available in 2026... ### Sacubitril/Valsartan **Generic:** sacubitril/valsartan Findability: 72/100 | Insurance: $10–$295 | Cash: $45–$700 What Is Sacubitril/Valsartan (Entresto)? Sacubitril/valsartan (brand name: Entresto) is a prescription heart failure medication combining two active ingredients into a unique twice-daily tablet. It is the first and only FDA-approved angiotensin receptor-neprilysin inhibitor (ARNI) in the United States, approved on July 7, 2015. Manufactured by Novartis Pharmaceuticals Corporation, Entresto generated $7.8 billion in global sales in 2024. Sacubitril/valsartan is FDA-approved to reduce the risk... ### Saizen **Generic:** Saizen Findability: 50/100 | Shortage: active | Insurance: $30–$100 | Cash: $700–$1,500 What Is Saizen? Saizen is a brand-name prescription medication containing Somatropin, a recombinant human growth hormone (rhGH) manufactured by EMD Serono. It is FDA-approved for treating pediatric growth failure due to inadequate secretion of endogenous growth hormone, as well as adult growth hormone deficiency — whether childhood-onset or adult-onset due to pituitary disease, surgery, radiation therapy, or trauma. Saizen is a subcutaneous injection that must be reconstituted from a... ### Sandostatin **Generic:** octreotide Findability: 45/100 | Shortage: active | Insurance: $0–$500 | Cash: $40–$8,500 What Is Sandostatin? Sandostatin is a brand name for octreotide acetate, a synthetic somatostatin analog manufactured by Novartis. It is a man-made version of somatostatin — a natural hormone produced by the hypothalamus, pancreas, and gastrointestinal tract that acts as the body's "off switch" for hormone secretion. Sandostatin is FDA-approved for three conditions: acromegaly (excess growth hormone from a pituitary tumor), carcinoid syndrome (severe flushing and diarrhea from metastatic... ### Santyl **Generic:** collagenase topical Findability: 68/100 | Shortage: resolved | Insurance: $0–$50 | Cash: $333–$450+ What Is Santyl (Collagenase)? Santyl is the brand name for collagenase ointment, a prescription topical medication used to remove dead tissue from chronic wounds and severe burns. It is manufactured by Smith & Nephew, Inc. and is the only FDA-approved enzymatic debriding ointment in the United States. Healthcare professionals have prescribed Santyl for more than 50 years. Santyl is FDA-approved for two indications: debriding chronic dermal ulcers (including diabetic foot ulcers, pressure... ### Saxenda **Generic:** Saxenda Findability: 55/100 | Shortage: monitoring | Insurance: $25–$300 | Cash: $1,165–$1,800 What Is Saxenda? Saxenda (liraglutide) is an FDA-approved injectable prescription medication for chronic weight management. It is manufactured by Novo Nordisk and belongs to a class of drugs called GLP-1 receptor agonists. Saxenda is approved for adults with a BMI of 30 or greater (obesity) or a BMI of 27 or greater with at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol. It is also approved for adolescents aged 12 and older with obesity.... ### Scopolamine **Generic:** scopolamine Findability: 40/100 | Shortage: active | Insurance: $0–$50 | Cash: $30–$168 What Is Scopolamine? Scopolamine is a prescription anticholinergic medication used to prevent nausea and vomiting. It belongs to the antimuscarinic drug class and is derived from belladonna alkaloids — a family of compounds with a centuries-long history in medicine. In the United States, the most familiar form is a small transdermal patch worn behind the ear, sold under the brand name Transderm Scop and in generic versions from multiple manufacturers. Each patch delivers a controlled dose of... ### Seasonique **Generic:** levonorgestrel/ethinyl estradiol extended-cycle Findability: 62/100 | Insurance: $0–$30 | Cash: $21–$515 What Is Seasonique? Seasonique is an extended-cycle combination oral contraceptive manufactured by Teva Pharmaceuticals. It contains levonorgestrel (0.15 mg, a synthetic progestin) and ethinyl estradiol (0.03 mg, a synthetic estrogen) in 84 active tablets, followed by 7 low-dose estrogen tablets containing ethinyl estradiol 0.01 mg only. This 91-day cycle design gives patients approximately four periods per year instead of twelve. Seasonique is FDA-approved for prevention of pregnancy and is... ### Secnidazole **Generic:** secnidazole Findability: 62/100 | Insurance: $25–$75 | Cash: $180–$550 What Is Secnidazole (Solosec)? Secnidazole is a nitroimidazole antimicrobial antibiotic sold under the brand name Solosec. It was FDA-approved on September 15, 2017, and is manufactured by Lupin Pharmaceuticals. Solosec is the only FDA-approved single-dose oral treatment for bacterial vaginosis in the United States. Secnidazole is FDA-approved for two conditions: bacterial vaginosis (BV) in females aged 12 and older, and trichomoniasis in patients aged 12 and older. It comes as oral granules... ### Semglee **Generic:** Semglee Findability: 65/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $80–$350 What Is Semglee? Semglee (Insulin Glargine-yfgn) is a long-acting basal insulin analog manufactured by Mylan (Viatris). It is an interchangeable biosimilar to Lantus, meaning it can be substituted at the pharmacy without requiring a new prescription from your doctor. Semglee is FDA-approved to improve blood sugar control in adults and children (ages 6 and older) with Type 1 diabetes and adults with Type 2 diabetes. It provides steady insulin coverage for approximately 24 hours with once-daily... ### Serevent **Generic:** salmeterol Findability: 72/100 | Insurance: $35–$100 | Cash: $420–$557 What Is Serevent? Serevent Diskus is the brand name for salmeterol xinafoate inhalation powder, a prescription medication made by GlaxoSmithKline (GSK). It was first approved by the FDA in 1994 and is classified as a long-acting beta-2 adrenergic agonist (LABA). Each inhalation delivers 50 mcg of salmeterol through a breath-activated Diskus dry powder inhaler. Serevent is FDA-approved for three indications: maintenance treatment of asthma (ages 4+, always used with an inhaled corticosteroid),... ### Seroquel XR **Generic:** quetiapine xr Findability: 82/100 | Insurance: $0–$30 | Cash: $30–$65 What Is Seroquel XR? Seroquel XR (quetiapine fumarate extended-release) is an atypical antipsychotic (second-generation antipsychotic) in the dibenzothiazepine chemical class. Originally developed by AstraZeneca and now distributed in the U.S. by Cheplapharm Arzneimittel GmbH, it is available both as brand-name Seroquel XR and as widely available generic quetiapine fumarate extended-release tablets. Seroquel XR is FDA-approved for schizophrenia (adults and adolescents 13+), bipolar I disorder... ### Sertraline **Generic:** sertraline Findability: 72/100 | Insurance: $0–$15 | Cash: $5–$40 What Is Sertraline? Sertraline is a prescription antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class. Originally sold under the brand name Zoloft by Pfizer, it was FDA-approved on December 30, 1991, and has been available as a generic since 2006. It is one of the most prescribed medications in the United States. Sertraline is FDA-approved for major depressive disorder (MDD), obsessive-compulsive disorder (OCD) in adults and children age 6+, panic disorder,... ### Seysara **Generic:** sarecycline Findability: 42/100 | Insurance: $35–$60 | Cash: $175–$1,325 What Is Seysara? Seysara is the brand name for sarecycline, a narrow-spectrum tetracycline-class antibiotic approved by the FDA in October 2018 for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 9 years of age and older. Manufactured by Almirall, LLC, it was the first new oral antibiotic specifically developed for acne in over 40 years. Unlike older tetracyclines such as doxycycline and minocycline, sarecycline has a narrow antimicrobial... ### Silenor **Generic:** doxepin Findability: 72/100 | Insurance: $0–$80 | Cash: $43–$650 What Is Silenor? Silenor is a brand-name prescription sleep medication that contains doxepin at low doses of 3 mg or 6 mg. It is FDA-approved for the treatment of insomnia characterized by difficulties with sleep maintenance — meaning it is specifically designed to help adults who wake up in the middle of the night or too early in the morning and cannot return to sleep. Originally approved by the FDA in March 2010 and now manufactured by Currax Pharmaceuticals, Silenor represents a novel use... ### Silka Cream **Generic:** terbinafine hydrochloride cream 1% Findability: 85/100 | Insurance: $0–$5 | Cash: $10–$17 What Is Silka Cream? Silka Antifungal Cream is an over-the-counter topical medication used to treat common fungal skin infections. It contains terbinafine hydrochloride 1% as its active ingredient — the same active ingredient found in Lamisil AT. It is distributed by Genomma Lab USA, Inc. and is available without a prescription at major retailers including Walmart, CVS, Walgreens, and Amazon. Silka is labeled for use in adults and children 12 years and older. It comes in a 1 oz (30g) tube... ### Silver Sulfadiazine **Generic:** silver sulfadiazine Findability: 74/100 | Insurance: $0–$25 | Cash: $14–$65 What Is Silver Sulfadiazine? Silver sulfadiazine is a topical antimicrobial cream used to prevent and treat bacterial infections in second- and third-degree burn wounds. It was first approved by the FDA in 1973 under the brand name Silvadene (manufactured by Pfizer). Today, it is available as a generic medication sold under names including SSD, SSD Cream, and Thermazene. Silver sulfadiazine is a prescription-only medication in the United States. It is available as a 1% topical cream in... ### Sinemet **Generic:** carbidopa/levodopa Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $9–$80 What Is Sinemet? Sinemet is a brand-name prescription medication containing two active ingredients: carbidopa and levodopa. It is classified as a dopaminergic antiparkinsonism agent and has been the gold-standard treatment for Parkinson's disease for more than five decades. The brand-name Sinemet (originally manufactured by Merck) has been discontinued, but generic carbidopa/levodopa remains widely available and therapeutically equivalent. The FDA has approved carbidopa/levodopa to treat... ### Sirolimus **Generic:** sirolimus Findability: 72/100 | Insurance: $0–$50 | Cash: $35–$500 What Is Sirolimus? Sirolimus — also known as rapamycin and sold under the brand name Rapamune — is a prescription immunosuppressant medication used primarily to prevent organ rejection after kidney transplantation and to treat a rare lung disease called lymphangioleiomyomatosis (LAM). It belongs to a drug class called mTOR inhibitors. Sirolimus was originally isolated in 1972 from a bacterium (Streptomyces hygroscopicus) found in soil samples from Easter Island (Rapa Nui), which is how the... ### Skyrizi **Generic:** risankizumab Findability: 45/100 | Insurance: $0–$30/dose | Cash: $22,000–$90,000+/yr What Is Skyrizi? Skyrizi (risankizumab-rzaa) is a prescription biologic medication made by AbbVie Inc. It is a humanized monoclonal antibody classified as an interleukin-23 (IL-23) antagonist. Skyrizi is FDA-approved for four conditions in adults: moderate to severe plaque psoriasis (April 2019), active psoriatic arthritis (January 2022), moderately to severely active Crohn's disease (June 2022), and moderately to severely active ulcerative colitis. It is not a controlled substance and has no... ### Slow-Fe XR **Generic:** ferrous sulfate Findability: 82/100 | Insurance: Not covered | Cash: $8–$20 What Is Slow-Fe XR? Slow-Fe XR is a brand-name extended-release iron supplement containing ferrous sulfate — the form of oral iron most frequently recommended by doctors. Each tablet provides 45 mg of elemental iron (equivalent to 142 mg of ferrous sulfate) using a controlled-release hydrogel matrix that gradually releases iron over several hours, reducing the stomach irritation common with standard iron tablets. Slow-Fe XR is classified as an over-the-counter (OTC) dietary supplement and... ### Sodium Chloride **Generic:** Sodium Chloride Findability: 75/100 | Insurance: $0–$10 | Cash: $3–$30 What Is Sodium Chloride? Sodium Chloride is an electrolyte replenisher and isotonic crystalloid solution used across nearly every area of medicine. It is one of the most widely administered medications in the world. Common uses include: Replacing extracellular fluid in cases of dehydration, blood loss, or sepsis Treating metabolic alkalosis with associated fluid loss Diluting and delivering IV medications Priming hemodialysis equipment Nasal irrigation for congestion and sinus... ### Sodium Citrate **Generic:** sodium citrate and citric acid Findability: 62/100 | Insurance: $0–$20 | Cash: $6–$40 What Is Sodium Citrate? Sodium Citrate is a prescription oral solution classified as a urinary alkalinizer and systemic alkalinizer. It is sold under brand names including Bicitra, Cytra-2, Oracit, and Virtrate, and is widely available in generic form as Sodium Citrate and Citric Acid Oral Solution USP. Each teaspoonful (5 mL) contains 500 mg of sodium citrate dihydrate and 334 mg of citric acid monohydrate, providing the equivalent of 1 mEq of bicarbonate per mL. Sodium Citrate is primarily... ### Sodium Phosphate, Dibasic/Sodium Phosphate, Monobasic **Generic:** sodium phosphate dibasic/sodium phosphate monobasic Findability: 72/100 | Insurance: $0–$100 | Cash: $113–$305 What Is Sodium Phosphate, Dibasic/Sodium Phosphate, Monobasic? Sodium phosphate, dibasic/sodium phosphate, monobasic — sold under the brand name OsmoPrep — is an FDA-approved prescription osmotic laxative used to clean the colon before a colonoscopy. It is available as oral tablets (1.5 g each), and a complete course consists of 32 tablets taken in two split doses. A separate intravenous (IV) formulation is used in hospitals to treat hypophosphatemia (low blood phosphorus) and as an additive... ### Sodium Polystyrene Sulfonate **Generic:** Sodium Polystyrene Sulfonate Findability: 50/100 | Shortage: active | Insurance: $0–$15 | Cash: $6–$50 What Is Sodium Polystyrene Sulfonate? Sodium Polystyrene Sulfonate (commonly known by the brand names Kayexalate and Kionex) is a potassium-binding resin used to treat hyperkalemia — dangerously high potassium levels in the blood. It is most commonly prescribed for patients with chronic kidney disease or end-stage renal disease whose kidneys cannot adequately remove excess potassium. The medication has been a mainstay of hyperkalemia treatment for decades and is available as a powder that you... ### Sodium Zirconium Cyclosilicate **Generic:** sodium zirconium cyclosilicate Findability: 75/100 | Insurance: $0–$100 | Cash: $869–$1,043 What Is Sodium Zirconium Cyclosilicate (Lokelma)? Sodium zirconium cyclosilicate, sold under the brand name Lokelma by AstraZeneca, is an FDA-approved prescription medication for the treatment of hyperkalemia (high blood potassium levels) in adults. It was approved by the FDA on May 18, 2018. Sodium zirconium cyclosilicate belongs to the drug class of potassium binders (cation exchange resins). Lokelma comes as a powder in individual foil packets (5 g and 10 g sizes) that is mixed with water... ### Solu-Cortef **Generic:** hydrocortisone sodium succinate Findability: 62/100 | Shortage: resolved | Insurance: $0–$20 | Cash: $13–$50 What Is Solu-Cortef? Solu-Cortef is the brand name for hydrocortisone sodium succinate for injection, USP, manufactured by Pfizer (Pharmacia & Upjohn Company LLC). It is an injectable corticosteroid — a synthetic form of the stress hormone cortisol — used when rapid IV or IM action is required. Effects are evident within one hour of IV administration. The drug is available as a sterile powder reconstituted before injection. It comes in the ACT-O-VIAL single-dose system in four strengths: 100... ### Somatropin **Generic:** somatropin Findability: 35/100 | Shortage: active | Insurance: $0–$200 | Cash: $350–$3,000+ What Is Somatropin? Somatropin is a recombinant human growth hormone (rhGH) — a synthetic biologic that is chemically identical to the growth hormone naturally produced by the pituitary gland. It is made through recombinant DNA technology, ensuring consistent purity without the disease-transmission risks of earlier cadaver-derived formulations. Somatropin is available under multiple brand names, each manufactured by different pharmaceutical companies. The most widely available brands in 2026... ### Sonidegib **Generic:** sonidegib Findability: 45/100 | Insurance: $10–$500+/month | Cash: $14,800/month What Is Sonidegib (Odomzo)? Sonidegib, sold under the brand name Odomzo, is an oral targeted cancer therapy classified as a Hedgehog pathway inhibitor. It was FDA-approved on July 24, 2015, for the treatment of adult patients with locally advanced basal cell carcinoma (laBCC). The drug is manufactured and marketed in the United States by Sun Pharmaceutical Industries, Inc. Sonidegib is indicated specifically for adults with laBCC that has recurred following surgery or radiation therapy, or... ### Soolantra **Generic:** ivermectin Findability: 72/100 | Insurance: $30–$100+ | Cash: $94–$974 What Is Soolantra? Soolantra is the brand name for ivermectin 1% topical cream, manufactured by Galderma Laboratories, L.P. It was approved by the U.S. FDA on December 23, 2014, for the treatment of inflammatory lesions of rosacea in adults. Generic ivermectin 1% cream is also available and is considered bioequivalent. Rosacea is a chronic inflammatory skin condition that causes persistent redness, visible blood vessels, and inflammatory bumps and pustules—primarily on the face. Soolantra is... ### Sotalol **Generic:** sotalol Findability: 68/100 | Shortage: active | Insurance: $0–$30 | Cash: $10–$600 What Is Sotalol? Sotalol is a prescription antiarrhythmic medication used to treat serious heart rhythm disorders, including ventricular tachycardia and atrial fibrillation (AFib). It is sold under the brand names Betapace, Betapace AF, Sorine, and Sotylize (the oral solution formulation). Generic sotalol tablets are widely available and are the most commonly prescribed form. Sotalol is unique among antiarrhythmics in that it acts through two distinct mechanisms: it is both a... ### Spironolactone **Generic:** spironolactone Findability: 72/100 | Shortage: resolved | Insurance: $0–$15 | Cash: $6–$37 What Is Spironolactone? Spironolactone is a prescription medication classified as a mineralocorticoid receptor antagonist (MRA) and potassium-sparing diuretic. Originally developed in the late 1950s, it works by competitively blocking aldosterone receptors in the kidneys, preventing sodium and water retention while preserving potassium. It is also a nonselective androgen receptor blocker, giving it a broad range of clinical applications. It was formerly sold under the brand name Aldactone... ### Spravato **Generic:** esketamine Findability: 35/100 | Insurance: $10–$50/session | Cash: $600–$1,200/session What Is Spravato? Spravato (esketamine) is a prescription nasal spray manufactured by Janssen Pharmaceuticals (Johnson & Johnson) and FDA-approved for treatment-resistant depression (TRD) in adults. It was first approved on March 5, 2019, and as of January 2025, became the first and only FDA-approved monotherapy for TRD. Unlike traditional oral antidepressants that target serotonin or norepinephrine, Spravato works through a completely different mechanism — blocking NMDA receptors in the... ### Spritam **Generic:** levetiracetam Findability: 48/100 | Insurance: $10–$200 | Cash: $640–$690 What Is Spritam? Spritam is the brand name for levetiracetam tablets for oral suspension — and it holds a unique distinction in pharmaceutical history: it is the world's first FDA-approved 3D-printed prescription drug. Approved by the FDA in August 2015 and launched in the US in March 2016, Spritam is manufactured by Aprecia Pharmaceuticals using their proprietary ZipDose® technology. Spritam is an antiepileptic medication approved for three types of seizure disorders: partial-onset seizures... ### Stahist AD **Generic:** chlorcyclizine / pseudoephedrine Findability: 55/100 | Insurance: $0–$30 | Cash: $23–$31 What Is Stahist AD? Stahist AD is a brand-name combination medication manufactured by Magna Pharmaceuticals, Inc. Its generic name is chlorcyclizine hydrochloride / pseudoephedrine hydrochloride. Each tablet contains chlorcyclizine 25 mg (a first-generation antihistamine) and pseudoephedrine 60 mg (a nasal decongestant). It is also available as a grape-flavored liquid containing 9.375 mg/30 mg per 5 mL. Stahist AD is also marketed under the brand name NasOpen. It is used to relieve symptoms... ### Stelara **Generic:** ustekinumab Findability: 72/100 | Insurance: $5–$80 | Cash: $7,000–$21,000+ What Is Stelara? Stelara is the brand name for ustekinumab, a biologic injectable medication manufactured by Janssen Biotech (a Johnson & Johnson company). It belongs to the class of human monoclonal antibodies and is classified as an interleukin-12 and interleukin-23 (IL-12/IL-23) antagonist. Stelara was first approved by the FDA in September 2009 for moderate-to-severe plaque psoriasis in adults. Stelara is FDA-approved for four conditions: moderate-to-severe plaque psoriasis (adults and... ### Sterile Water for Injection **Generic:** water for injection Findability: 35/100 | Shortage: active | Insurance: $0–$30 | Cash: $1–$15 What Is Sterile Water for Injection? Sterile Water for Injection, USP (SWFI) is a sterile, nonpyrogenic, preservative-free pharmaceutical diluent. Chemically designated H₂O with a pH of 5.0–7.0, it is manufactured to strict FDA standards for sterility, freedom from pyrogens, and particulate matter limits. It is available only in single-dose containers ranging from 2 mL vials to 3,000 mL pharmacy bulk packages, and is labeled 'Rx only' in the United States. SWFI has no pharmacological effect... ### Stop Lice Maximum Strength **Generic:** pyrethrin/piperonyl butoxide Findability: 72/100 | Insurance: $0–$5 | Cash: $8–$20 What Is Stop Lice Maximum Strength? Stop Lice Maximum Strength is an over-the-counter (OTC) pediculicide shampoo used to treat head lice, body lice, and pubic lice in adults and children 2 years of age and older. It is available without a prescription at pharmacies, grocery stores, and online retailers. The active ingredients are pyrethrum extract (equivalent to 0.33% pyrethrins) and piperonyl butoxide 4%. Pyrethrins are natural insecticides derived from chrysanthemum flowers; piperonyl... ### Strattera **Generic:** atomoxetine Findability: 78/100 | Shortage: resolved | Insurance: $0–$30 | Cash: $15–$60 What Is Strattera (Atomoxetine)? Atomoxetine, formerly sold as the brand name Strattera, is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) in children ages 6 and older, adolescents, and adults. It was FDA-approved on November 26, 2002, becoming the first non-stimulant medication ever approved for ADHD in the United States. Unlike stimulant ADHD medications such as Adderall (amphetamine) and Ritalin (methylphenidate), atomoxetine is not a controlled... ### Sucralfate **Generic:** sucralfate Findability: 65/100 | Insurance: $0–$40 | Cash: $12–$150 What Is Sucralfate? Sucralfate (brand name Carafate) is a prescription gastrointestinal protectant used primarily to treat and prevent peptic ulcers. It is classified as a mucosal protectant and antiulcer agent. Chemically, sucralfate is a basic aluminum complex of sucrose octasulfate that forms a thick, viscous, protective barrier over ulcer sites in the stomach and small intestine. The FDA first approved sucralfate in 1981. It is available as a generic medication in tablet (1g) and oral... ### Sudo-Tab **Generic:** pseudoephedrine Findability: 72/100 | Insurance: $0–$10 | Cash: $5–$18 What Is Sudo-Tab? Sudo-Tab is a brand name for pseudoephedrine, an oral nasal decongestant that has been used for decades to relieve nasal and sinus congestion. Pseudoephedrine belongs to a drug class called sympathomimetic amines — medications that mimic the body's fight-or-flight response to narrow blood vessels and reduce swelling in the nasal passages. It is used to treat congestion caused by the common cold, flu, hay fever, sinusitis, and ear congestion from ear infections. It comes in... ### Suflave **Generic:** polyethylene glycol 3350, sodium sulfate, potassium chloride, magnesium sulfate, and sodium chloride Findability: 72/100 | Insurance: $0–$50 | Cash: $134–$170 What Is Suflave? Suflave (polyethylene glycol 3350, sodium sulfate, potassium chloride, magnesium sulfate, and sodium chloride for oral solution) is a prescription-only osmotic laxative approved by the FDA in June 2023. It is used exclusively to cleanse the colon before a colonoscopy in adults. The medication is manufactured by Azurity Pharmaceuticals and marketed by Braintree Laboratories. Suflave comes as a powder that is mixed with water to produce a lemon-lime flavored solution — designed... ### Sulfamethoxazole/Trimethoprim **Generic:** sulfamethoxazole/trimethoprim Findability: 88/100 | Insurance: $0–$10 | Cash: $2–$35 What Is Sulfamethoxazole/Trimethoprim? Sulfamethoxazole/trimethoprim (TMP-SMX) is a combination antibiotic that has been FDA-approved since 1973. It combines two drugs that work synergistically: sulfamethoxazole (a sulfonamide) and trimethoprim (an antifolate). Together, they block two consecutive steps in bacterial folate synthesis, disrupting DNA production and killing or stopping bacterial growth. Sold under brand names Bactrim, Bactrim DS, Septra, Septra DS, and Sulfatrim, TMP-SMX is... ### Sumatriptan **Generic:** sumatriptan Findability: 88/100 | Insurance: $5–$30 | Cash: $9–$97 What Is Sumatriptan? Sumatriptan is a prescription medication used to treat acute migraine headaches with or without aura in adults. Sold under the brand name Imitrex (and now widely available as a generic), sumatriptan was the first triptan ever approved by the FDA, receiving approval in 1992. It remains the most widely prescribed acute migraine medication in the United States. Sumatriptan belongs to the class of drugs called selective serotonin (5-HT1B/1D) receptor agonists, commonly known... ### Sunosi **Generic:** solriamfetol Findability: 72/100 | Insurance: $9–$60 | Cash: $963–$1,230 What Is Sunosi? Sunosi (solriamfetol) is a prescription wakefulness-promoting medication approved by the FDA in March 2019. It is used to improve wakefulness in adults with excessive daytime sleepiness (EDS) associated with narcolepsy or obstructive sleep apnea (OSA). Sunosi is the brand name for solriamfetol, currently distributed in the United States by Axsome Therapeutics. Sunosi was the first dopamine and norepinephrine reuptake inhibitor (DNRI) approved for treating EDS. It is available... ### Suprax **Generic:** cefixime Findability: 55/100 | Insurance: $5–$30 | Cash: $14–$252 What Is Suprax (Cefixime)? Suprax is the brand name for cefixime, a third-generation cephalosporin antibiotic taken by mouth. It's FDA-approved for adults and children six months and older with specific bacterial infections, and has been used in the United States since its initial FDA approval in 1986. Brand-name Suprax was withdrawn from the US market in 2002 and reintroduced by Lupin Pharmaceuticals in 2004. Suprax is FDA-approved to treat uncomplicated urinary tract infections (UTIs),... ### Suprep Bowel Prep Kit **Generic:** Suprep Bowel Prep Kit Findability: 82/100 | Insurance: $10–$50 | Cash: $35–$170 What Is Suprep Bowel Prep Kit? Suprep Bowel Prep Kit is a prescription osmotic laxative used to cleanse the colon before a colonoscopy. It is FDA-approved for adults and pediatric patients 12 years of age and older. The kit contains two bottles of a flavored oral solution concentrate made up of sodium sulfate, potassium sulfate, and magnesium sulfate. Patients drink each dose diluted with water, followed by additional water, as part of a split-dose regimen the evening before and morning of... ### Syeda 28 Day **Generic:** drospirenone and ethinyl estradiol Findability: 78/100 | Insurance: $0–$30 | Cash: $25–$147 What Is Syeda 28 Day? Syeda 28 Day is a combination oral contraceptive (birth control pill) containing two synthetic hormones: drospirenone (3 mg) and ethinyl estradiol (0.03 mg). It is a generic equivalent of the brand-name pill Yasmin, originally made by Bayer and first approved in the United States in 2001. Syeda was launched as a generic by Sandoz in 2011 and is currently manufactured by Laboratorios Leon Farma in Spain and marketed by Xiromed. Each 28-day blister pack contains 21 yellow... ### Symbravo **Generic:** meloxicam and rizatriptan Findability: 60/100 | Insurance: $10–$150 | Cash: $1,110–$1,420 What Is Symbravo? Symbravo is a prescription oral tablet that combines two active ingredients: meloxicam (20 mg), a COX-2 preferential non-steroidal anti-inflammatory drug (NSAID), and rizatriptan (10 mg), a fast-acting triptan. Manufactured by Axsome Therapeutics, it received FDA approval on January 30, 2025, making it one of the newest prescription migraine medications available in the United States. Symbravo is FDA-approved for the acute treatment of migraine with or without aura in... ### Symdeko **Generic:** tezacaftor/ivacaftor Findability: 65/100 | Insurance: $0–$500 | Cash: $25,000–$27,000 What Is Symdeko? Symdeko is a prescription CFTR (cystic fibrosis transmembrane conductance regulator) modulator manufactured by Vertex Pharmaceuticals. It combines two active ingredients — tezacaftor (a CFTR corrector) and ivacaftor (a CFTR potentiator) — into a co-packaged daily treatment for cystic fibrosis (CF). Symdeko is also known internationally as Symkevi. Symdeko was first FDA-approved in February 2018 for patients ages 12 and older, and expanded in 2020 to cover patients ages 6 and... ### Symproic **Generic:** Symproic Findability: 45/100 | Shortage: active | Insurance: $0–$75 | Cash: $484–$746 What Is Symproic? Symproic (Naldemedine) is a prescription medication approved by the FDA to treat opioid-induced constipation (OIC) in adults with chronic non-cancer pain. It belongs to a class of drugs called peripherally-acting mu-opioid receptor antagonists (PAMORAs). Symproic helps restore normal bowel function in patients taking opioid pain medications without reducing the pain-relieving effects of those opioids. It was originally developed by Shionogi Inc. and is marketed in the U.S. by... ### Synarel **Generic:** nafarelin acetate Findability: 55/100 | Insurance: $50–$200 | Cash: $3,100–$3,500 What Is Synarel? Synarel is the brand name for nafarelin acetate, a prescription nasal spray medication manufactured by Pfizer (G.D. Searle LLC). First FDA-approved in February 1991, Synarel is a synthetic analog of gonadotropin-releasing hormone (GnRH) — a naturally occurring hormone that regulates sex hormone production in the brain and reproductive system. Synarel is classified as a GnRH agonist and belongs to the same drug class as leuprolide (Lupron), goserelin (Zoladex), and triptorelin... ### Synthroid **Generic:** levothyroxine Findability: 72/100 | Insurance: $0–$30 | Cash: $10–$80 What Is Synthroid? Synthroid is the brand name for levothyroxine sodium, a synthetic form of the thyroid hormone T4 (thyroxine). It is manufactured by AbbVie and is consistently among the top three most prescribed medications in the United States. Synthroid is classified as a thyroid hormone replacement drug and is chemically identical to the T4 hormone normally produced by the thyroid gland. Synthroid is FDA-approved to treat hypothyroidism — a condition where the thyroid gland doesn't... ### Tacrolimus **Generic:** Tacrolimus Findability: 35/100 | Shortage: active | Insurance: $10–$50 | Cash: $30–$722 What Is Tacrolimus? Tacrolimus is a calcineurin inhibitor immunosuppressant medication used primarily to prevent organ rejection in patients who have received a liver, kidney, or heart transplant. It is one of the most widely used anti-rejection drugs in transplant medicine. Tacrolimus is also available as a topical ointment (Protopic) for treating moderate to severe atopic dermatitis (eczema). Brand-name versions include Prograf (immediate-release capsules), Astagraf XL (extended-release... ### Tamiflu **Generic:** Tamiflu Findability: 40/100 | Shortage: active | Insurance: $0–$75 | Cash: $25–$250 What Is Tamiflu? Tamiflu (oseltamivir phosphate) is a prescription antiviral medication manufactured by Genentech (Roche). It is FDA-approved for treating acute, uncomplicated influenza A and B in patients 2 weeks of age and older who have been symptomatic for no more than 48 hours. It is also approved for preventing (prophylaxis) influenza in patients 1 year and older. Tamiflu works best when started within the first 48 hours of flu symptoms and can reduce the duration of illness by 1–2 days. ### Tamoxifen **Generic:** tamoxifen Findability: 88/100 | Insurance: $0–$30 | Cash: $20–$110 What Is Tamoxifen? Tamoxifen is a selective estrogen receptor modulator (SERM) used to treat and prevent estrogen receptor-positive (ER+) breast cancer in women and men. It works by blocking estrogen receptors in breast tissue, preventing estrogen from stimulating cancer cell growth. Tamoxifen is sold under the brand names Nolvadex (tablet) and Soltamox (oral solution), and is widely available as a generic. FDA-approved uses include: adjuvant treatment of early and advanced ER-positive breast... ### Tazorac **Generic:** tazarotene Findability: 72/100 | Insurance: $0–$50 | Cash: $40–$600 What Is Tazorac? Tazorac is the brand name for tazarotene, a synthetic third-generation topical retinoid derived from vitamin A. First approved by the FDA in 1997, it is available as a cream and gel in 0.05% and 0.1% concentrations. Generic tazarotene is also available and is FDA-approved as bioequivalent to brand Tazorac. Tazorac is FDA-approved for three conditions: stable plaque psoriasis (cream and gel 0.05% and 0.1%), acne vulgaris (cream and gel 0.1%, for patients 12 and older), and... ### TdVax **Generic:** tetanus and diphtheria toxoids adsorbed Findability: 5/100 | Shortage: active | Insurance: $0 | Cash: $0–$65 What Is TdVax? TdVax (Tetanus and Diphtheria Toxoids, Adsorbed) was a vaccine manufactured by MassBiologics, a nonprofit biologic manufacturer in Massachusetts, and distributed by Grifols USA. It was FDA-approved for active immunization against tetanus and diphtheria in persons 7 years of age and older. Important: TdVax is permanently discontinued. MassBiologics halted production in early 2024, and all remaining inventory distributed by Grifols USA was exhausted by approximately June 2024.... ### Tegretol XR **Generic:** carbamazepine Findability: 72/100 | Insurance: $0–$30 | Cash: $29–$247 What Is Tegretol XR? Tegretol XR is the brand name for carbamazepine extended-release tablets, manufactured by Novartis. It is an anticonvulsant (anti-seizure) medication that has been used clinically since the 1960s. The "XR" formulation releases the active drug gradually over 12 hours, allowing for twice-daily dosing and more stable blood levels compared to immediate-release carbamazepine. Tegretol XR is FDA-approved for epilepsy (partial seizures, generalized tonic-clonic seizures, and... ### Temazepam **Generic:** temazepam Findability: 72/100 | Insurance: $0–$15 | Cash: $10–$45 What Is Temazepam? Temazepam is a prescription benzodiazepine medication sold under the brand name Restoril. It is FDA-approved for the short-term treatment of insomnia, including trouble falling asleep and trouble staying asleep through the night. Temazepam has been available as a generic medication for decades and is manufactured by multiple companies including Sandoz, Mylan, and Amneal. Temazepam is taken orally as a capsule in strengths of 7.5 mg, 15 mg, 22.5 mg, and 30 mg. The standard... ### Temodar **Generic:** temozolomide Findability: 60/100 | Insurance: $0–$600+ | Cash: $113–$600+ What Is Temodar? Temodar is the brand name for temozolomide, an oral alkylating chemotherapy agent first approved by the FDA in August 1999. It is manufactured by Merck Sharp & Dohme LLC and is available in capsule strengths of 5 mg, 20 mg, 100 mg, 140 mg, 180 mg, and 250 mg, as well as a 100 mg intravenous formulation for patients who cannot swallow capsules. Temodar is FDA-approved for adults with newly diagnosed glioblastoma multiforme (GBM) — the most aggressive primary brain tumor — and... ### Temozolomide **Generic:** temozolomide Findability: 60/100 | Insurance: $0–$300 | Cash: $50–$3,420 What Is Temozolomide? Temozolomide, sold under the brand name Temodar, is an oral chemotherapy medication used to treat brain tumors. It is the cornerstone of treatment for glioblastoma multiforme (GBM) — the most common and aggressive primary brain cancer in adults — given alongside radiation therapy and then as maintenance treatment. It is also FDA-approved for anaplastic astrocytoma. Temozolomide is classified as an alkylating agent. Unlike most chemotherapy drugs, it is taken orally as a... ### Tenivac **Generic:** tetanus and diphtheria toxoids adsorbed Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $50–$97 What Is Tenivac? Tenivac is a brand-name Td (tetanus and diphtheria toxoids adsorbed) vaccine manufactured by Sanofi Pasteur. It is given as a 0.5 mL intramuscular injection and is FDA-approved for active immunization against tetanus and diphtheria in persons 7 years of age and older. As of 2024, Tenivac is the only Td vaccine available in the United States after MassBiologics discontinued its TdVax product. Tenivac is used for routine booster immunization every 10 years, for primary... ### Tenofovir Alafenamide **Generic:** Tenofovir Alafenamide Findability: 55/100 | Shortage: monitoring | Insurance: $0–$75 | Cash: $1,500–$1,800 What Is Tenofovir Alafenamide? Tenofovir Alafenamide (TAF), sold under the brand name Vemlidy, is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection in adults and pediatric patients 6 years of age and older weighing at least 25 kg with compensated liver disease. It is manufactured by Gilead Sciences. TAF is a newer, improved prodrug of tenofovir that delivers the active drug more efficiently to target cells, allowing a lower dose with fewer kidney and bone side... ### Terconazole **Generic:** terconazole Findability: 78/100 | Insurance: $3–$50 | Cash: $17–$130 What Is Terconazole? Terconazole is a prescription-only triazole antifungal medication approved by the FDA in December 1987 for the treatment of vulvovaginal candidiasis (vaginal yeast infections) in adult females. It is sold under the brand names Terazol 3, Terazol 7, and Zazole, and is widely available as a generic medication from multiple manufacturers. Terconazole comes in three formulations for vaginal use: a 0.4% vaginal cream (applied nightly for 7 days), a 0.8% vaginal cream (applied... ### Terrell **Generic:** isoflurane Findability: 72/100 | Insurance: $0 patient cost | Cash: $40–$150 per bottle What Is Terrell (Isoflurane)? Terrell is the brand name for isoflurane USP, a general inhalational anesthetic manufactured by Piramal Critical Care, Inc. FDA-approved since 1979, Terrell is a clear, colorless, nonflammable liquid that is vaporized and inhaled to induce and maintain general anesthesia during surgical procedures. Terrell is available in 100 mL and 250 mL amber glass bottles containing 99.9% isoflurane. It must be delivered through a calibrated isoflurane-specific vaporizer... ### Tesamorelin **Generic:** tesamorelin Findability: 40/100 | Shortage: resolved | Insurance: $0–$500 | Cash: $2,400–$2,800 What Is Tesamorelin? Tesamorelin is a synthetic growth hormone-releasing factor (GHRF) analog — a lab-made version of a natural hormone your hypothalamus produces to signal the pituitary gland to release growth hormone. It is the only FDA-approved medication in the United States specifically indicated for the reduction of excess abdominal fat (visceral adipose tissue) in HIV-infected adults with lipodystrophy. Tesamorelin was first approved by the FDA in 2010 under the brand name Egrifta. It... ### Testim **Generic:** testosterone Findability: 75/100 | Insurance: $0–$100 | Cash: $87–$760 What Is Testim? Testim is a brand-name prescription testosterone gel used to treat hypogonadism — a condition in which the body does not produce enough testosterone — in adult men. It contains 1% testosterone in a clear-to-translucent gel applied once daily to the shoulders and upper arms. Each tube contains 5 grams of gel delivering 50 milligrams of testosterone. Testim is manufactured by Endo Pharmaceuticals and classified as a Schedule III controlled substance under the Controlled... ### Testosterone **Generic:** Testosterone Findability: 55/100 | Shortage: monitoring | Insurance: $5–$30 | Cash: $30–$900 What Is Testosterone? Testosterone is the primary male sex hormone and an anabolic steroid. When prescribed as a medication, exogenous Testosterone replaces or supplements the body's natural production in men diagnosed with hypogonadism — a condition where the body does not produce enough Testosterone on its own. It is FDA-approved for testosterone replacement therapy (TRT) in adult males with primary hypogonadism (congenital or acquired) and hypogonadotropic hypogonadism. It is also used... ### Tetrabenazine **Generic:** tetrabenazine Findability: 72/100 | Insurance: $0–$200 | Cash: $60–$4,400 What Is Tetrabenazine? Tetrabenazine (brand name Xenazine) is a prescription oral medication classified as a VMAT2 inhibitor (vesicular monoamine transporter 2 inhibitor). It was FDA-approved on August 15, 2008, making it the first medication ever approved in the United States specifically for the treatment of chorea associated with Huntington's disease (HD). Tetrabenazine is available as oral tablets in 12.5 mg and 25 mg strengths. It does not cure Huntington's disease or slow its... ### Tetracaine **Generic:** tetracaine Findability: 65/100 | Insurance: $0–$20 | Cash: $29–$43 What Is Tetracaine? Tetracaine (also known as amethocaine) is an ester-class local anesthetic that has been used in medicine since 1941. It is listed on the World Health Organization's Essential Medicines List for its effectiveness, affordability, and wide clinical utility across ophthalmology, anesthesiology, and emergency medicine. Tetracaine is available in three primary formulations: a 0.5% ophthalmic solution (eye drops) for in-office eye procedures, an injectable form for spinal... ### Tetracycline **Generic:** tetracycline Findability: 55/100 | Shortage: resolved | Insurance: $0–$20 | Cash: $44–$110 What Is Tetracycline? Tetracycline is a broad-spectrum antibiotic belonging to the tetracycline drug class — one of the oldest and most versatile classes of antibiotics still in clinical use. Available as tetracycline hydrochloride (HCl) oral capsules in 250 mg and 500 mg strengths, it is prescribed for a wide range of bacterial infections including acne, sexually transmitted infections, respiratory tract infections, Lyme disease, rickettsial infections, and H. pylori eradication. First... ### Theo-24 XR **Generic:** theophylline Findability: 40/100 | Shortage: active | Insurance: $0–$15 | Cash: $10–$40 What Is Theo-24 XR? Theo-24 XR is the brand name for theophylline anhydrous extended-release capsules designed for once-daily dosing. It belongs to the methylxanthine class of bronchodilators and is used for the long-term management of chronic asthma and COPD (emphysema and chronic bronchitis). The drug has been in use since the 1950s and remains an important option for patients who need an affordable oral bronchodilator. The original Theo-24 brand was manufactured by Endo Pharmaceuticals in... ### Thera-Gesic **Generic:** menthol/methyl salicylate topical Findability: 80/100 | Insurance: $0–$0 | Cash: $9–$16 What Is Thera-Gesic? Thera-Gesic is an over-the-counter topical pain cream manufactured by MainPointe Pharmaceuticals, LLC. It contains two active ingredients: 15% methyl salicylate and 1% menthol. Methyl salicylate is a salicylate counterirritant derived from oil of wintergreen, while menthol is a natural analgesic from mint plants. Thera-Gesic is classified as a topical rubefacient — a product that relieves pain by creating sensory stimulation at the skin surface. It is available without a... ### Thyrogen Kit **Generic:** thyrotropin alfa Findability: 55/100 | Insurance: $0–$500 | Cash: $4,000–$5,500 What Is Thyrogen Kit? Thyrogen Kit is the brand name for thyrotropin alfa — a recombinant human thyroid-stimulating hormone (rhTSH) produced by Genzyme Corporation, a Sanofi company. First approved by the FDA in December 1998, Thyrogen Kit is a specialty injectable biologic used in patients with well-differentiated thyroid cancer who have previously undergone a near-total or total thyroidectomy. Thyrogen Kit has two FDA-approved indications: (1) as an adjunctive diagnostic tool for serum... ### Tiagabine **Generic:** tiagabine Findability: 78/100 | Insurance: $0–$50 | Cash: $45–$432 What Is Tiagabine? Tiagabine (brand name Gabitril) is an FDA-approved anticonvulsant medication used to help control partial (focal) seizures in adults and children 12 years and older with epilepsy. It was first approved by the FDA in 1997 and is available as both brand-name and generic tablets. Tiagabine is always used as adjunctive therapy — in combination with other antiepileptic drugs — rather than as a standalone medication. It is a second- or third-line option typically prescribed when... ### Timolol **Generic:** Timolol Findability: 55/100 | Shortage: monitoring | Insurance: $0–$15 | Cash: $4–$196 What Is timolol? Timolol (also known by brand names Timoptic, Betimol, Istalol, and Blocadren) is a nonselective beta-adrenergic blocker (beta-blocker) that has been used for decades to treat eye and heart conditions. In its ophthalmic form, timolol is one of the most widely prescribed medications for open-angle glaucoma and ocular hypertension, helping to lower intraocular pressure and prevent vision loss. In its oral tablet form, timolol is approved for hypertension (high blood pressure),... ### Tinidazole **Generic:** tinidazole Findability: 75/100 | Insurance: $0–$30 | Cash: $28–$70 What Is Tinidazole? Tinidazole is a prescription antibiotic and antiprotozoal agent belonging to the nitroimidazole drug class. It is sold under the brand name Tindamax in the United States and was FDA-approved in 2004. Generic tinidazole is manufactured by several companies including Hikma Pharmaceuticals, Edenbridge Pharmaceuticals, and Novel Laboratories. Internationally, it is also known by the brand name Fasigyn. Tinidazole is FDA-approved for four conditions: trichomoniasis (a sexually... ### Tirosint **Generic:** Tirosint Findability: 62/100 | Shortage: monitoring | Insurance: $25–$75 | Cash: $150–$250 What Is Tirosint? Tirosint is a brand-name prescription medication containing Levothyroxine Sodium in a unique gel capsule formulation. It is manufactured by IBSA Pharma and is used as thyroid hormone replacement therapy for patients with hypothyroidism (underactive thyroid). It is also used as an adjunct to surgery and radioiodine therapy for the management of certain thyroid cancers. What sets Tirosint apart from standard Levothyroxine tablets is its minimal inactive ingredients —... ### Tivicay **Generic:** Tivicay Findability: 45/100 | Shortage: active | Insurance: $0–$73 | Cash: $2,259–$2,925 What Is Tivicay and What Does It Do? Tivicay (dolutegravir) is a prescription medication used to treat HIV-1 infection in adults and children weighing at least 3 kg. It belongs to a class of drugs called integrase strand transfer inhibitors (INSTIs) and is always used in combination with other antiretroviral medications as part of a complete HIV treatment regimen. Tivicay is manufactured by ViiV Healthcare, a company majority-owned by GSK. It is also a key component of several combination HIV... ### Tobradex **Generic:** Tobradex Findability: 65/100 | Shortage: monitoring | Insurance: $10–$30 | Cash: $28–$350 What Is Tobradex? Tobradex is a prescription ophthalmic combination medication containing Tobramycin (an aminoglycoside antibiotic) and Dexamethasone (a corticosteroid). It is used to treat bacterial eye infections while simultaneously reducing inflammation. Common uses include steroid-responsive inflammatory ocular conditions with bacterial infection, post-surgical eye inflammation, bacterial conjunctivitis with an inflammatory component, and blepharitis with bacterial involvement. Tobradex... ### Tolak **Generic:** fluorouracil Findability: 72/100 | Insurance: $0–$80 | Cash: $40–$235 What Is Tolak? Tolak is a brand-name prescription topical cream containing fluorouracil at a 4% concentration (40 mg per gram of cream). It is manufactured by Hill Dermaceuticals, Inc. and classified as a nucleoside metabolic inhibitor — a form of topical chemotherapy. Tolak is FDA-approved for the treatment of actinic keratosis (AK) lesions on the face, ears, and scalp. Actinic keratosis consists of rough, scaly, precancerous skin patches caused by chronic ultraviolet radiation exposure.... ### Tolterodine XR **Generic:** tolterodine tartrate Findability: 78/100 | Insurance: $0–$30 | Cash: $19–$250 What Is Tolterodine XR? Tolterodine XR (tolterodine tartrate extended-release capsules) is a prescription medication used to treat overactive bladder (OAB) in adults. Previously sold under the brand name Detrol LA by Pfizer — which has since been discontinued — the generic form is now widely produced by multiple manufacturers including Torrent Pharmaceuticals, Teva, and Viatris. Tolterodine XR is an antimuscarinic drug that works by relaxing the detrusor (bladder) muscle, reducing the... ### Topamax **Generic:** topiramate Findability: 90/100 | Insurance: $0–$10 | Cash: $2–$35 What Is Topamax? Topamax is the brand name for topiramate, a second-generation anticonvulsant (anti-seizure) medication first approved by the FDA on December 24, 1996. Today, the vast majority of prescriptions are filled with generic topiramate, which has been available since 2006 and is therapeutically equivalent to the brand. Topiramate is FDA-approved to treat and prevent seizures in adults and children as young as 2 years old, and to prevent migraine headaches in adults and adolescents 12... ### Toprol XR **Generic:** metoprolol succinate Findability: 72/100 | Insurance: $0–$30 | Cash: $9–$65 What Is Toprol XR? Toprol XR is a brand name for metoprolol succinate extended-release, a once-daily prescription tablet used to treat high blood pressure (hypertension), chronic chest pain (angina pectoris), and heart failure with reduced ejection fraction (HFrEF). It belongs to a class of drugs called beta-1 selective (cardioselective) beta blockers and was first approved by the FDA in 1992. The extended-release formulation delivers metoprolol continuously over 24 hours through a... ### Toujeo **Generic:** Toujeo Findability: 55/100 | Shortage: monitoring | Insurance: $0–$50 | Cash: $35–$550 What Is Toujeo? Toujeo is a brand-name, long-acting basal insulin manufactured by Sanofi. Its active ingredient is insulin glargine at a concentration of 300 units/mL (U-300) — three times more concentrated than Lantus (U-100). Toujeo is FDA-approved for the treatment of type 1 diabetes and type 2 diabetes in adults. As a basal insulin, Toujeo provides a steady level of insulin over approximately 24–36 hours to help control blood sugar between meals and overnight. It is injected... ### Tranexamic Acid **Generic:** tranexamic acid Findability: 78/100 | Shortage: resolved | Insurance: $0–$30 | Cash: $27–$127 What Is Tranexamic Acid? Tranexamic acid (TXA) is a prescription antifibrinolytic medication that prevents excessive bleeding by stopping blood clots from breaking down too quickly. First synthesized in 1962 by Japanese researchers Shosuke and Utako Okamoto, it is now on the World Health Organization's List of Essential Medicines and is used across numerous medical specialties worldwide. It is FDA-approved for two indications: treating heavy menstrual bleeding (as oral tablets, 1,300 mg three... ### Transanosil **Generic:** capsaicin/menthol/methyl salicylate topical lotion Findability: 75/100 | Insurance: $0–$30 | Cash: $20–$120 What Is Transanosil? Transanosil is a brand-name topical pain relief lotion classified as a topical rubefacient. It contains three active ingredients: capsaicin (0.025%), menthol (10%), and methyl salicylate (30%). It is used for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains, muscle soreness and stiffness, and bruises. Other brand names with the same generic formula include Dendracin Neurodendraxcin, Ultracin,... ### Tranxene **Generic:** clorazepate Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $29–$155 What Is Tranxene? Tranxene is the brand name for clorazepate dipotassium, a long-acting benzodiazepine medication. It has been FDA-approved for use in the United States since 1967 and belongs to the same drug class as diazepam (Valium), lorazepam (Ativan), and alprazolam (Xanax). Tranxene is available as oral tablets in three strengths: 3.75 mg, 7.5 mg, and 15 mg. Tranxene is FDA-approved for three indications: anxiety disorders, adjunctive therapy for partial seizures (in patients age 9 and... ### Tranylcypromine **Generic:** tranylcypromine Findability: 48/100 | Insurance: $0–$50 | Cash: $68–$540 What Is Tranylcypromine? Tranylcypromine — sold under the brand name Parnate — is a monoamine oxidase inhibitor (MAOI) antidepressant that has been used since 1961. It is FDA-approved for the treatment of major depressive disorder (MDD) in adult patients who have not responded adequately to other antidepressants. Tranylcypromine is strictly a second-line or later treatment, indicated only after trials of other antidepressant classes have been insufficient. Off-label uses with clinical... ### Travatan Z **Generic:** travoprost Findability: 82/100 | Insurance: $0–$50 | Cash: $28–$230 What Is Travatan Z? Travatan Z is the brand name for travoprost 0.004% ophthalmic solution — a prescription eye drop used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It belongs to the prostaglandin analog drug class and works by increasing the flow of aqueous fluid out of the eye through the uveoscleral pathway. The FDA first approved travoprost (as Travatan) in 2001. The improved Travatan Z formulation, which uses a gentler sofZia... ### Travoprost **Generic:** travoprost Findability: 82/100 | Insurance: $0–$50 | Cash: $30–$190 What Is Travoprost? Travoprost is a prescription ophthalmic solution used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It belongs to the class of medications known as prostaglandin analogs — drugs that mimic the natural compound prostaglandin F2α to enhance fluid drainage from the eye. The FDA first approved travoprost (as Travatan) in 2001, and the improved Travatan Z formulation (using the gentler sofZia preservative) was approved... ### Trelegy **Generic:** Trelegy Findability: 72/100 | Insurance: $30–$75 | Cash: $580–$700 What Is Trelegy? Trelegy Ellipta is a once-daily triple combination inhaler made by GlaxoSmithKline (GSK). It contains three active ingredients — Fluticasone Furoate (an inhaled corticosteroid), Umeclidinium (a long-acting muscarinic antagonist), and Vilanterol (a long-acting beta2-agonist). It is FDA-approved for the maintenance treatment of COPD (including chronic bronchitis and emphysema) and for maintenance treatment of asthma in adults aged 18 and older. Trelegy is not intended for acute... ### Tresiba **Generic:** insulin degludec Findability: 45/100 | Shortage: active | Insurance: $0–$35 | Cash: $100–$500 What Is Tresiba? Tresiba is the brand name for insulin degludec, an ultra-long-acting basal insulin analog manufactured by Novo Nordisk. It was FDA-approved on September 25, 2015, and became commercially available in the United States in January 2016. Tresiba is indicated to improve glycemic control in adults and children aged 1 year and older with type 1 or type 2 diabetes mellitus. Tresiba is a "basal" or "background" insulin — it provides a steady, continuous level of insulin throughout... ### Tretinoin **Generic:** tretinoin Findability: 72/100 | Shortage: active | Insurance: $0–$30 | Cash: $28–$95 What Is Tretinoin? Tretinoin — also known as all-trans retinoic acid (ATRA) — is a prescription medication derived from vitamin A (retinol). It belongs to the retinoid class of drugs and is the biologically active acid form of vitamin A, meaning it works directly without requiring conversion by the body. First approved by the FDA for acne vulgaris in 1971, it remains one of the most clinically studied and prescribed topical medications in dermatology. Tretinoin is available in topical forms... ### Treximet **Generic:** Treximet Findability: 45/100 | Shortage: active | Insurance: $30–$75 | Cash: $130–$900 What Is Treximet? Treximet is a prescription combination medication used for the acute treatment of migraine attacks with or without aura in adults. It combines two active ingredients — Sumatriptan (a triptan) and Naproxen Sodium (an NSAID) — into a single tablet. By pairing both drugs together, Treximet attacks migraine pain through two different mechanisms simultaneously, which clinical studies have shown to be more effective than either drug taken alone. It is manufactured by Currax... ### Tri-Lo-Mili **Generic:** norgestimate/ethinyl estradiol Findability: 72/100 | Insurance: $0–$30 | Cash: $9–$130 What Is Tri-Lo-Mili? Tri-Lo-Mili (norgestimate and ethinyl estradiol) is a prescription triphasic combination oral contraceptive pill manufactured by Aurobindo Pharma USA. It is a generic equivalent of the discontinued brand-name Ortho Tri-Cyclen Lo and is FDA-approved for use in females of reproductive potential to prevent pregnancy. Tri-Lo-Mili is classified as a "low-dose" contraceptive because it contains only 0.025 mg of ethinyl estradiol — lower than many other combination pills. It is... ### Tri-Lo-Sprintec 28 Day **Generic:** norgestimate / ethinyl estradiol Findability: 82/100 | Insurance: $0–$20 | Cash: $22–$126 What Is Tri-Lo-Sprintec 28 Day? Tri-Lo-Sprintec 28 Day (norgestimate/ethinyl estradiol) is a combination oral contraceptive (COC) pill that contains two synthetic hormones: norgestimate (a progestin) and ethinyl estradiol (an estrogen). It is a triphasic, low-dose formulation, meaning the norgestimate dose changes across three phases of the 28-day cycle while the estrogen dose (25 mcg ethinyl estradiol) remains constant at a lower level than many other combination pills. Tri-Lo-Sprintec is a... ### Tri-Sprintec 28 Day **Generic:** norgestimate and ethinyl estradiol (triphasic) Findability: 88/100 | Insurance: $0–$5 | Cash: $17–$77 What Is Tri-Sprintec 28 Day? Tri-Sprintec 28 Day is a combination oral contraceptive containing two synthetic hormones: norgestimate (a third-generation progestin) and ethinyl estradiol (a synthetic estrogen). It is a generic equivalent of Ortho Tri-Cyclen, which was discontinued by Janssen Pharmaceuticals after multiple generics entered the market. Tri-Sprintec is classified as a triphasic oral contraceptive — meaning each 28-day pack contains three different hormone doses across the first... ### Triamcinolone **Generic:** triamcinolone acetonide Findability: 45/100 | Shortage: active | Insurance: $0–$15 | Cash: $3–$80 What Is Triamcinolone? Triamcinolone acetonide is a synthetic corticosteroid (glucocorticoid) that has been FDA-approved since the 1950s. It is one of the most versatile anti-inflammatory medications available, coming in forms ranging from topical cream and ointment to injectable suspension, nasal spray, and dental paste. Brand names include Kenalog (injection and topical), Nasacort (OTC nasal spray), Triderm, Trianex, and Oralone (dental paste). As a medium-potency corticosteroid when... ### Tribenzor **Generic:** olmesartan/amlodipine/hydrochlorothiazide Findability: 76/100 | Insurance: $0–$60 | Cash: $36–$600 What Is Tribenzor? Tribenzor is a brand-name prescription tablet that combines three blood pressure medications into one daily dose. First approved by the FDA in 2010, it is currently marketed by Cosette Pharmaceuticals, Inc. Generic versions (olmesartan/amlodipine/hydrochlorothiazide) are available from multiple manufacturers including Teva and Par Health USA. Tribenzor is FDA-approved for the treatment of high blood pressure (hypertension) in adults who have not achieved adequate control on... ### Trifluoperazine **Generic:** trifluoperazine Findability: 52/100 | Shortage: resolved | Insurance: $0–$20 | Cash: $10–$55 What Is Trifluoperazine? Trifluoperazine is a first-generation (typical) antipsychotic medication in the phenothiazine chemical class. It was FDA-approved in 1959 and was originally marketed under the brand name Stelazine, which is no longer available in the United States. All trifluoperazine in the US is now sold as a generic by manufacturers including Mylan (Viatris), Sandoz, and Upsher-Smith. Trifluoperazine is primarily used to treat schizophrenia — a serious mental illness affecting how... ### Trifluridine **Generic:** Trifluridine Findability: 45/100 | Shortage: active | Insurance: $10–$75 | Cash: $201–$400 What Is Trifluridine? Trifluridine is an antiviral ophthalmic solution used to treat eye infections caused by herpes simplex virus (HSV) types 1 and 2. It is specifically approved for primary keratoconjunctivitis and recurrent epithelial keratitis. Trifluridine is applied as eye drops directly to the affected eye and is available as a generic medication. The brand-name version was sold as Viroptic. ### Trijardy XR **Generic:** empagliflozin/linagliptin/metformin hydrochloride extended-release Findability: 62/100 | Insurance: $0–$100 | Cash: $350–$750 What Is Trijardy XR? Trijardy XR is a prescription oral tablet that combines three diabetes medications into a single once-daily extended-release dose: empagliflozin (an SGLT2 inhibitor), linagliptin (a DPP-4 inhibitor), and metformin hydrochloride extended-release (a biguanide). It was FDA-approved in 2020 and is manufactured by Boehringer Ingelheim. Trijardy XR is used as an adjunct to diet and exercise to improve blood sugar (glycemic) control in adults with type 2 diabetes mellitus. The... ### Trileptal **Generic:** Trileptal Findability: 70/100 | Shortage: monitoring | Insurance: $60–$80 | Cash: $11–$815 What Is Trileptal? Trileptal is the brand name for Oxcarbazepine, an anticonvulsant (antiepileptic) medication manufactured by Novartis Pharmaceuticals. It is FDA-approved to treat partial (focal) seizures in adults and children aged 4 to 16, either as a standalone treatment or alongside other seizure medications. Doctors also prescribe Trileptal off-label for bipolar disorder, trigeminal neuralgia, and neuropathic pain. ### Trimo-San **Generic:** oxyquinoline sulfate / sodium lauryl sulfate Findability: 48/100 | Insurance: $0–$0 | Cash: $37–$58 What Is Trimo-San? Trimo-San is a brand-name prescription vaginal jelly manufactured by CooperSurgical, Inc. It contains two active ingredients: oxyquinoline sulfate (hydroxyquinoline) at 0.025% and sodium lauryl sulfate at 0.01%. The gel is formulated to a pH of 4 — matching the normal acidic environment of a healthy vagina. Trimo-San is used primarily by women who wear vaginal pessaries — medical devices inserted into the vagina to support the pelvic organs in cases of pelvic organ prolapse... ### Trintellix **Generic:** Trintellix Findability: 72/100 | Shortage: monitoring | Insurance: $10–$75 | Cash: $300–$610 What Is Trintellix? Trintellix (vortioxetine) is a prescription antidepressant FDA-approved in 2013 for the treatment of Major Depressive Disorder (MDD) in adults. It is manufactured by Takeda Pharmaceuticals in partnership with Lundbeck. The medication was originally marketed as Brintellix but was renamed Trintellix in 2016 to avoid confusion with the blood thinner Brilinta. Trintellix is classified as a serotonin modulator and stimulator (SMS), which distinguishes it from traditional SSRIs... ### Triprolidine **Generic:** triprolidine Findability: 75/100 | Insurance: $0–$20 | Cash: $7–$27 What Is Triprolidine? Triprolidine is a first-generation H1 antihistamine in the alkylamine chemical class, available over the counter in the United States. It has been used since the 1950s to relieve symptoms of allergic rhinitis, hay fever, common cold, urticaria (hives), and allergic conjunctivitis. Triprolidine is not a controlled substance. Triprolidine is available as a standalone oral solution (brand names: Histex, Histex PD Drops, Zymine) for both adult and pediatric use, and in... ### Triumeq **Generic:** abacavir/dolutegravir/lamivudine Findability: 62/100 | Insurance: $0–$100+ | Cash: $3,929–$4,606 What Is Triumeq? Triumeq is a once-daily, fixed-dose combination antiretroviral medication used to treat HIV-1 (human immunodeficiency virus type 1) infection. Manufactured by ViiV Healthcare and first approved by the FDA in August 2014, each purple, oval Triumeq tablet contains three active ingredients: abacavir 600 mg, dolutegravir 50 mg, and lamivudine 300 mg. Triumeq is approved for adults and adolescents aged 12 years and older who weigh at least 40 kg (88 lbs). Triumeq PD — the... ### Trivora 28 Day **Generic:** levonorgestrel and ethinyl estradiol Findability: 73/100 | Insurance: $0–$15 | Cash: $17–$89 What Is Trivora 28 Day? Trivora 28 Day is a prescription triphasic combination oral contraceptive containing levonorgestrel (a synthetic progestin) and ethinyl estradiol (a synthetic estrogen). It is FDA-approved for the prevention of pregnancy and is taken once daily for 28 consecutive days per menstrual cycle. The 28-tablet pack consists of 6 blue tablets (Phase 1: 0.05 mg LNG / 0.03 mg EE), 5 white tablets (Phase 2: 0.075 mg LNG / 0.04 mg EE), 10 pink tablets (Phase 3: 0.125 mg LNG / 0.03... ### Trulance **Generic:** plecanatide Findability: 72/100 | Insurance: $25–$100 | Cash: $620–$830 What Is Trulance? Trulance is the brand name for plecanatide, a prescription guanylate cyclase-C (GC-C) agonist manufactured by Salix Pharmaceuticals. It was FDA-approved on January 19, 2017 for chronic idiopathic constipation (CIC) in adults, with a second approval following in January 2018 for irritable bowel syndrome with constipation (IBS-C). It is the only other FDA-approved drug in the GC-C agonist class alongside Linzess (linaclotide). Trulance is taken as a single 3 mg tablet once... ### Trulicity **Generic:** dulaglutide Findability: 38/100 | Shortage: active | Insurance: $25–$150 | Cash: $825–$1,395 What Is Trulicity? Trulicity (dulaglutide) is a brand-name prescription medication manufactured by Eli Lilly and Company. It was FDA-approved in September 2014 as a once-weekly injectable treatment for type 2 diabetes mellitus in adults, and later expanded to include children ages 10 and older. In 2020, two higher doses (3 mg and 4.5 mg) were approved, expanding the dosing options for patients who need additional glycemic control. Trulicity is also FDA-approved to reduce the risk of major... ### Truvada **Generic:** emtricitabine/tenofovir disoproxil fumarate Findability: 88/100 | Insurance: $0–$30 | Cash: $21–$1,685 What Is Truvada? Truvada is a brand-name prescription medication manufactured by Gilead Sciences, Inc. It is a fixed-dose combination tablet containing two nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs): emtricitabine (FTC, 200 mg) and tenofovir disoproxil fumarate (TDF, 300 mg). Both components block the reverse transcriptase enzyme that HIV needs to copy itself, preventing viral replication. The FDA first approved Truvada for HIV-1 treatment on August 2, 2004. In July 2012,... ### Twirla **Generic:** Twirla Findability: 55/100 | Shortage: monitoring | Insurance: $0–$25 | Cash: $200–$290 What Is Twirla? Twirla is a prescription combined hormonal contraceptive (CHC) patch that prevents pregnancy. It contains two hormones — Levonorgestrel (a progestin) and Ethinyl Estradiol (an estrogen) — delivered through the skin via a small, round transdermal patch using Skinfusion® adhesive technology. Twirla is FDA-approved for the prevention of pregnancy in women with a BMI less than 30 kg/m². It is applied once weekly for 3 weeks, followed by one patch-free week, making it a convenient... ### Twyneo **Generic:** tretinoin and benzoyl peroxide topical Findability: 60/100 | Insurance: $0–$100 | Cash: $45–$797 What Is Twyneo? Twyneo is a prescription topical cream containing tretinoin (0.1%) and benzoyl peroxide (3%) for the treatment of acne vulgaris. It is the first and only FDA-approved fixed-dose combination of these two widely used acne-fighting ingredients. Twyneo was approved by the FDA on July 27, 2021, and is manufactured by Sol-Gel Technologies, marketed in the U.S. by Mayne Pharma. Twyneo is indicated for adults and pediatric patients 9 years of age and older with acne vulgaris,... ### Twynsta **Generic:** telmisartan/amlodipine Findability: 45/100 | Shortage: active | Insurance: $0–$50 | Cash: $120–$480 What Is Twynsta? Twynsta is a prescription combination blood pressure medication that contains two active ingredients in a single tablet: telmisartan (an angiotensin II receptor blocker, or ARB) and amlodipine (a dihydropyridine calcium channel blocker, or CCB). It was originally FDA-approved on October 16, 2009, and manufactured by Boehringer Ingelheim Pharmaceuticals. Twynsta is FDA-approved for the treatment of hypertension (high blood pressure) in adults, alone or with other... ### Tyenne **Generic:** tocilizumab-aazg Findability: 70/100 | Insurance: $0–$100 | Cash: $390–$3,000+ What Is Tyenne? Tyenne (tocilizumab-aazg) is an FDA-approved biologic medication and a biosimilar to Actemra (tocilizumab), manufactured by Fresenius Kabi USA, LLC. It was first approved by the FDA on March 5, 2024, making it the first tocilizumab biosimilar in the United States to be approved in both intravenous (IV) and subcutaneous (SC) formulations. Tyenne belongs to the interleukin-6 (IL-6) receptor antagonist class of drugs — a type of targeted biologic therapy that works by blocking a... ### Tymlos **Generic:** abaloparatide Findability: 42/100 | Insurance: $0–$200 | Cash: $2,577–$4,300 What Is Tymlos? Tymlos is the brand name for abaloparatide, a prescription injectable medication used to treat osteoporosis in adults at high risk of bone fracture. It is classified as a parathyroid hormone-related protein (PTHrP) analog — a synthetic version of a naturally occurring protein in the human body that regulates bone formation. Unlike most osteoporosis medications, which work by slowing bone breakdown (antiresorptive agents), Tymlos is an anabolic agent that actively stimulates... ### Ubrelvy **Generic:** ubrogepant Findability: 72/100 | Insurance: $0–$150 | Cash: $1,100–$1,450 What Is Ubrelvy? Ubrelvy (ubrogepant) is a prescription brand-name tablet used for the acute treatment of migraine with or without aura in adults. It received FDA approval on December 23, 2019, making it the first oral CGRP receptor antagonist (gepant) approved for acute migraine treatment. It is manufactured by AbbVie (originally developed by Allergan). Ubrelvy belongs to a class called CGRP receptor antagonists, also known as "gepants." It is taken at the first sign of a migraine attack —... ### Ultram XR **Generic:** tramadol hydrochloride Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $25–$105 What Is Ultram XR? Ultram XR is a brand name for tramadol hydrochloride extended-release tablets — a centrally acting synthetic opioid analgesic indicated for the management of moderate to moderately severe chronic pain in adults requiring around-the-clock treatment. The Ultram and Ultram ER brand names have been discontinued in the United States; generic tramadol ER tablets remain available in 100 mg, 200 mg, and 300 mg strengths. Unlike immediate-release tramadol (taken every 4–6 hours),... ### Umeclidinium/Vilanterol **Generic:** umeclidinium/vilanterol Findability: 75/100 | Insurance: $30–$100 | Cash: $270–$600 What Is Umeclidinium/Vilanterol (Anoro Ellipta)? Umeclidinium/vilanterol, sold under the brand name Anoro Ellipta, is a once-daily fixed-dose combination inhaler approved by the FDA in December 2013 for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It was the first LAMA/LABA combination inhaler approved in the United States. The inhaler combines two distinct bronchodilators: umeclidinium (62.5 mcg), a long-acting muscarinic antagonist (LAMA),... ### Unithroid **Generic:** levothyroxine sodium Findability: 72/100 | Insurance: $0–$43 | Cash: $25–$85 What Is Unithroid? Unithroid is a brand-name prescription thyroid hormone medication containing levothyroxine sodium — a synthetic form of T4, the principal hormone produced by the human thyroid gland. It was the first levothyroxine product to receive FDA New Drug Application (NDA) approval in August 2000, making it the reference standard for all other levothyroxine brands and generics. Unithroid is manufactured by Jerome Stevens Pharmaceuticals (JSP), a family-owned US-based pharmaceutical... ### Upneeq **Generic:** Upneeq Findability: 55/100 | Shortage: monitoring | Insurance: $30–$75 | Cash: $225–$350 What Is Upneeq? Upneeq (Oxymetazoline Hydrochloride Ophthalmic Solution, 0.1%) is a prescription eye drop approved by the FDA for the treatment of acquired blepharoptosis — commonly known as drooping upper eyelid — in adults. It is the first and only FDA-approved eye drop specifically designed to lift drooping eyelids without surgery. Upneeq is manufactured by RVL Pharmaceuticals, Inc. and is used once daily. It is also commonly prescribed off-label for cosmetic eyelid lifting and for... ### Urea **Generic:** urea Findability: 88/100 | Insurance: $0–$50 | Cash: $15–$141 What Is Urea Cream? Urea topical (also called carbamide) is a keratolytic emollient — a medication that both moisturizes and softens thickened, hardened skin and nails. It is available over-the-counter in concentrations from 2% to 20% and by prescription in concentrations from 20% to 50%. The urea in pharmaceutical preparations is synthetically manufactured, not derived from urine. Urea is sold under more than 60 brand names, including Carmol, Keralac, Aluvea, Kerafoam, Hydro 40, Gordons... ### Urocit-K XR **Generic:** potassium citrate extended release Findability: 72/100 | Insurance: $5–$30 | Cash: $13–$364 What Is Urocit-K XR? Urocit-K XR is the brand name for potassium citrate extended-release tablets, manufactured by Mission Pharmacal. It was FDA-approved in 1985 and is classified as a urinary pH modifier. The drug is prescribed to prevent kidney stones and treat renal tubular acidosis by alkalinizing the urine — raising urinary pH and increasing urinary citrate levels. The medication is available in three strengths: 5 mEq, 10 mEq, and 15 mEq extended-release wax-matrix tablets. FDA-approved... ### Uzedy **Generic:** risperidone Findability: 55/100 | Insurance: $0–$200/mo | Cash: $1,232–$3,080/mo What Is Uzedy? Uzedy is the brand name for risperidone extended-release injectable suspension for subcutaneous use, manufactured by Teva Pharmaceuticals in partnership with MedinCell. It is a long-acting injectable (LAI) atypical antipsychotic that delivers a steady release of risperidone over four to eight weeks using MedinCell's proprietary SteadyTeq™ polymer technology. Uzedy is FDA-approved for the treatment of schizophrenia in adults (approved April 28, 2023) and for the maintenance... ### Vagifem **Generic:** estradiol vaginal inserts Findability: 78/100 | Insurance: $0–$80 | Cash: $47–$377 What Is Vagifem? Vagifem is the brand name for estradiol vaginal inserts (10 mcg), manufactured by Novo Nordisk and FDA-approved since 1999. Each insert is a small, white, film-coated tablet that is placed inside the vagina using a disposable applicator. Once inserted, it dissolves slowly over several hours, releasing estradiol directly to vaginal tissue. Vagifem is prescribed to treat moderate to severe genitourinary syndrome of menopause (GSM) — also called vulvovaginal atrophy — including... ### Valacyclovir **Generic:** valacyclovir Findability: 88/100 | Insurance: $0–$30 | Cash: $19–$211 What Is Valacyclovir? Valacyclovir (brand name Valtrex) is a prescription antiviral medication used to treat infections caused by herpes viruses. It belongs to the class of drugs called purine nucleoside analogs and is specifically classified as a prodrug — meaning it converts into its active form (acyclovir) after being absorbed by the body. It is FDA-approved to treat cold sores (herpes labialis), genital herpes (initial and recurrent episodes), shingles (herpes zoster), chickenpox in... ### Valganciclovir **Generic:** valganciclovir Findability: 72/100 | Insurance: $0–$50 | Cash: $90–$3,400 What Is Valganciclovir? Valganciclovir (brand name Valcyte) is an oral antiviral medication used to prevent and treat infections caused by cytomegalovirus (CMV), a member of the herpesvirus family. It is a prodrug — meaning it is chemically converted inside the body into its active form, ganciclovir, after you swallow it. Valganciclovir is FDA-approved for the treatment of CMV retinitis in adults with AIDS, and for the prevention of CMV disease in adults and children after kidney, heart, or... ### Valium **Generic:** diazepam Findability: 72/100 | Insurance: $0–$15 | Cash: $4–$30 What Is Valium (Diazepam)? Valium is the brand name for diazepam, a long-acting benzodiazepine medication first introduced in 1963. It is FDA-approved to treat anxiety disorders, alcohol withdrawal symptoms, muscle spasms associated with upper motor neuron disorders, and as adjunctive therapy for seizure disorders and status epilepticus. It is also used for preoperative sedation and anxiety relief before medical procedures. Diazepam is available as generic tablets in 2 mg, 5 mg, and 10 mg... ### Valtoco **Generic:** diazepam nasal spray Findability: 52/100 | Insurance: $0–$100 | Cash: $1,760–$2,572 What Is Valtoco? Valtoco is the brand name for diazepam nasal spray, manufactured by Neurelis, Inc. It is the only FDA-approved intranasal formulation of diazepam available in the United States. First approved on January 10, 2020 for patients ages 6 and older, the FDA expanded the indication in April 2025 to include children as young as 2 years old. Valtoco is indicated for the acute treatment of intermittent, stereotypic episodes of frequent seizure activity—also known as seizure clusters or... ### Valtrex **Generic:** valacyclovir Findability: 78/100 | Insurance: $0–$30 | Cash: $11–$208 What Is Valtrex? Valtrex is a brand-name prescription antiviral medication. Its generic name is valacyclovir, and it is manufactured by GlaxoSmithKline. FDA-approved in December 1995, it has become one of the most widely prescribed medications in the United States — with over 7 million prescriptions filled annually as of 2023. Valtrex is used to treat infections caused by herpes viruses, including cold sores (herpes labialis), genital herpes (herpes simplex), and shingles (herpes zoster). It... ### Vanacof AC **Generic:** chlophedianol hydrochloride / pyrilamine maleate Findability: 52/100 | Insurance: $0–$25 | Cash: $25–$55 What Is Vanacof AC? Vanacof AC is an over-the-counter oral liquid manufactured by GM Pharmaceuticals, Inc. It combines two active ingredients: chlophedianol hydrochloride 12.5 mg (a non-narcotic cough suppressant) and pyrilamine maleate 25 mg (a first-generation antihistamine) per 30 mL dose. It is decongestant-free, alcohol-free, and not a controlled substance. Vanacof AC temporarily relieves cough due to minor throat and bronchial irritation, along with allergy symptoms including runny... ### Vancomycin **Generic:** Vancomycin Findability: 40/100 | Shortage: active | Insurance: $10–$50 | Cash: $39–$593 What Is Vancomycin? Vancomycin is a glycopeptide antibiotic used to treat serious bacterial infections caused by gram-positive organisms, particularly methicillin-resistant Staphylococcus aureus (MRSA). It is considered a last-line antibiotic for many life-threatening infections. The oral form is primarily used to treat Clostridioides difficile (C. diff) infections, staphylococcal enterocolitis, and pseudomembranous colitis. The IV form is used for systemic infections including endocarditis,... ### Varenicline **Generic:** varenicline Findability: 85/100 | Insurance: $0–$30 | Cash: $27–$410 What Is Varenicline? Varenicline is a prescription medication used to help adults quit smoking. It was originally sold under the brand name Chantix by Pfizer, which was voluntarily recalled in 2021 due to nitrosamine contamination and subsequently discontinued. FDA-approved generic varenicline tablets are widely available in 2026 from multiple manufacturers. Varenicline is also available as a nasal spray (Tyrvaya) for the treatment of dry eye disease — a separate formulation and indication... ### Vascepa **Generic:** icosapent ethyl Findability: 65/100 | Insurance: $9–$60 | Cash: $98–$422 What Is Vascepa? Vascepa is a brand-name prescription medication manufactured by Amarin Pharma, Inc. Its active ingredient is icosapent ethyl (IPE) — a highly purified ethyl ester form of eicosapentaenoic acid (EPA), an omega-3 fatty acid. Vascepa is the first and only FDA-approved medication to reduce the risk of major cardiovascular events in adults with elevated triglycerides who are already on statin therapy. The FDA approved Vascepa in July 2012 for reducing severe hypertriglyceridemia... ### Vaxchora **Generic:** cholera vaccine, live, oral Findability: 40/100 | Insurance: $0-$402 | Cash: $296-$402 What Is Vaxchora? Vaxchora (cholera vaccine, live, oral) is the only FDA-approved cholera vaccine in the United States. It is manufactured by Bavarian Nordic A/S and approved for active immunization against cholera caused by Vibrio cholerae serogroup O1 in persons ages 2 through 64 who are traveling to cholera-affected areas. Vaxchora was first approved by the FDA in June 2016 for adults ages 18–64. In December 2020, the FDA expanded approval to include children ages 2–17. It is a... ### Vazalore **Generic:** aspirin Findability: 45/100 | Shortage: active | Insurance: $0–$30 | Cash: $25–$45 What Is Vazalore? Vazalore is a brand-name formulation of aspirin (acetylsalicylic acid), available as a liquid-filled capsule in 81 mg and 325 mg doses. It was FDA-approved in March 2021 and is the first and only liquid-filled aspirin capsule available in the United States. Vazalore is manufactured by Greenwood Brands (formerly PLx Pharma) using their proprietary PLxGuard delivery technology. Unlike conventional aspirin tablets, Vazalore uses a phospholipid-aspirin complex that releases... ### Velphoro **Generic:** sucroferric oxyhydroxide Findability: 55/100 | Insurance: $0–$200 | Cash: $1,550–$2,160 What Is Velphoro? Velphoro is the brand name for sucroferric oxyhydroxide, an iron-based phosphate binder approved by the FDA in November 2013. It is indicated for the control of serum phosphorus levels in adults and pediatric patients 9 years of age and older with chronic kidney disease (CKD) on dialysis. There is no generic version available as of 2026. Velphoro is manufactured and distributed by Fresenius Medical Care North America. It comes as a round, brown, chewable tablet embossed with... ### Veltassa **Generic:** patiromer Findability: 45/100 | Insurance: $0–$150 | Cash: $977–$1,500 What Is Veltassa? Veltassa is the brand name for patiromer sorbitex calcium, an FDA-approved prescription medication used to treat hyperkalemia — dangerously elevated levels of potassium in the blood. Approved in October 2015, it was the first new potassium-binding medication approved in over 50 years. Veltassa is manufactured by Vifor Pharma, Inc. and is available only as a brand-name drug (no generic is currently available). Veltassa is an off-white powder that comes in single-use packets.... ### Vemlidy **Generic:** tenofovir alafenamide Findability: 65/100 | Insurance: $0–$200 | Cash: $1,500–$1,800 What Is Vemlidy? Vemlidy (tenofovir alafenamide, or TAF) is a prescription antiviral medication manufactured by Gilead Sciences. It is FDA-approved to treat chronic hepatitis B virus (HBV) infection in adults and pediatric patients 6 years of age and older who weigh at least 25 kg (55 lbs) and have compensated liver disease. Vemlidy comes as a 25 mg oral tablet taken once daily with food. Tenofovir alafenamide is also found as a component in several combination HIV medications (Biktarvy,... ### Venclexta **Generic:** Venclexta Findability: 40/100 | Shortage: active | Insurance: $0–$100 | Cash: $15,000–$16,000 What Is Venclexta? Venclexta (Venetoclax) is a targeted cancer therapy manufactured by AbbVie and Genentech (Roche). It is FDA-approved to treat chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML) in adults. Unlike traditional chemotherapy, Venclexta is a precision medicine that targets a specific protein called BCL-2 that cancer cells use to survive. For CLL and SLL, Venclexta can be used alone or in combination with other medications like... ### Venlafaxine XR **Generic:** venlafaxine Findability: 65/100 | Insurance: $0–$30 | Cash: $10–$45 What Is Venlafaxine XR? Venlafaxine XR (brand name: Effexor XR) is an extended-release antidepressant belonging to the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is FDA-approved for adults to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder. It is taken once daily with food. Originally marketed as Effexor by Wyeth (now Viatris), the extended-release formulation was introduced to allow once-daily... ### Venofer **Generic:** iron sucrose Findability: 72/100 | Shortage: resolved | Insurance: $0–$50 | Cash: $325–$869 What Is Venofer? Venofer is the brand name for iron sucrose injection, USP — a sterile intravenous (IV) iron replacement product manufactured by American Regent, Inc. under license from Vifor International Inc. in Switzerland. FDA-approved since 2000, Venofer is one of the most widely used IV iron products in the United States. Venofer is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD), including those on hemodialysis,... ### Ventolin **Generic:** albuterol Findability: 62/100 | Shortage: active | Insurance: $0–$30 | Cash: $25–$99 What Is Ventolin (Albuterol)? Ventolin HFA is a brand-name prescription inhaler manufactured by GlaxoSmithKline (GSK) containing albuterol sulfate — a short-acting beta-2 adrenergic agonist (SABA) bronchodilator. It is one of the most widely prescribed medications in the United States, used by people with asthma, COPD, and other respiratory conditions that cause airway narrowing. Albuterol is also known internationally as salbutamol. Ventolin was first launched in 1969 and received initial... ### Veozah **Generic:** Veozah Findability: 55/100 | Shortage: monitoring | Insurance: $0–$30 | Cash: $550–$765 What Is Veozah? Veozah (Fezolinetant) is a prescription medication approved by the FDA for the treatment of moderate to severe vasomotor symptoms (VMS) — commonly known as hot flashes and night sweats — caused by menopause. It belongs to a new class of drugs called neurokinin 3 (NK3) receptor antagonists, offering a nonhormonal option for women who cannot or prefer not to use hormone replacement therapy (HRT). Veozah is manufactured by Astellas Pharma and is taken as a once-daily 45 mg oral... ### Verapamil **Generic:** verapamil Findability: 72/100 | Insurance: $0–$30 | Cash: $8–$90 What Is Verapamil? Verapamil is a non-dihydropyridine calcium channel blocker — one of the oldest and most widely used heart medications in the world. It is FDA-approved for the treatment of hypertension (high blood pressure), chronic stable angina, vasospastic (Prinzmetal) angina, unstable angina, and several heart rhythm disorders including paroxysmal supraventricular tachycardia (PSVT) and atrial fibrillation/flutter. Off-label, it is widely used as the first-line preventive treatment for... ### Verkazia **Generic:** cyclosporine ophthalmic emulsion Findability: 42/100 | Shortage: active | Insurance: $0–$79 | Cash: $1,938–$2,159 What Is Verkazia? Verkazia (cyclosporine ophthalmic emulsion 0.1%) is a prescription eye drop manufactured by Harrow Eye, LLC. It is the first and only FDA-approved topical immunomodulator specifically indicated for the treatment of vernal keratoconjunctivitis (VKC) in children ages 4 and older and in adults. FDA approval was granted in June 2021. Vernal keratoconjunctivitis is a chronic, severe form of allergic inflammation of the eye. It primarily affects children and young adults, causing... ### Vestura **Generic:** drospirenone and ethinyl estradiol Findability: 78/100 | Shortage: resolved | Insurance: $0–$30 | Cash: $27–$178 What Is Vestura? Vestura is a combination oral contraceptive containing drospirenone (3 mg) and ethinyl estradiol (0.02 mg). It was manufactured by Teva Pharmaceuticals as a branded generic of Yaz. Each 28-day pack contains 24 active hormone tablets and 4 inert placebo tablets, following a 24/4 monophasic regimen. The Vestura brand name has been discontinued by Teva Pharmaceuticals. However, the same active ingredients — drospirenone 3 mg / ethinyl estradiol 0.02 mg — remain available from... ### Vevye **Generic:** cyclosporine ophthalmic solution 0.1% Findability: 62/100 | Insurance: $0–$100 | Cash: $59–$1,070 Vevye (cyclosporine ophthalmic solution 0.1%) is a prescription eye drop approved by the FDA on May 30, 2023, for the treatment of the signs and symptoms of dry eye disease in adults. It is the first and only cyclosporine-based product with an FDA indication covering both the signs and symptoms of dry eye disease. Vevye is manufactured by Harrow, Inc. (Nasdaq: HROW) using Novaliq's proprietary EyeSol technology — a water-free, preservative-free semifluorinated alkane (perfluorobutylpentane)... ### Viagra **Generic:** sildenafil Findability: 82/100 | Insurance: $0–$30 | Cash: $4–$80 What Is Viagra (Sildenafil)? Viagra is the brand name for sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor manufactured by Viatris (formerly Pfizer). It was FDA-approved on March 27, 1998, as the first oral therapy for erectile dysfunction in the United States. The same active ingredient (sildenafil) is also available under the brand name Revatio for the treatment of pulmonary arterial hypertension (PAH). Generic sildenafil — containing the identical active ingredient at the... ### Vienva 28 Day **Generic:** levonorgestrel/ethinyl estradiol Findability: 75/100 | Insurance: $0–$20 | Cash: $15–$65 What Is Vienva 28 Day? Vienva 28 Day is a combination oral contraceptive (COC) manufactured by Xiromed, LLC. It contains two synthetic hormones — levonorgestrel 0.1 mg (a progestin) and ethinyl estradiol 0.02 mg (an estrogen) — in a 28-day blister pack consisting of 21 white active tablets and 7 peach placebo tablets. It is FDA-approved for the prevention of pregnancy in females of reproductive potential. Vienva is a monophasic pill, meaning all 21 active tablets contain the same hormone... ### Vigamox **Generic:** moxifloxacin ophthalmic Findability: 80/100 | Insurance: $0–$50 | Cash: $15–$220 What Is Vigamox? Vigamox is the brand name for moxifloxacin hydrochloride ophthalmic solution 0.5%, a prescription antibiotic eye drop used to treat bacterial conjunctivitis (pink eye). It is manufactured as a sterile, preservative-free solution and distributed in the United States by Novartis Pharmaceuticals Corporation. Vigamox belongs to the fourth-generation fluoroquinolone class of antibiotics, offering broad-spectrum coverage against both gram-positive and gram-negative bacteria... ### Vilazodone **Generic:** Vilazodone Findability: 65/100 | Shortage: monitoring | Insurance: $10–$50 | Cash: $28–$383 What Is Vilazodone? Vilazodone (sold under the brand name Viibryd) is a prescription antidepressant approved by the FDA for the treatment of Major Depressive Disorder (MDD) in adults. It belongs to a unique drug class called Serotonin Partial Agonist-Reuptake Inhibitors (SPARIs), making it distinct from traditional SSRIs and SNRIs. Originally developed by Forest Laboratories and now marketed by AbbVie (Allergan), Vilazodone is also sometimes used off-label for Generalized Anxiety Disorder,... ### Viorele 28 Day **Generic:** desogestrel and ethinyl estradiol Findability: 80/100 | Insurance: $0–$20 | Cash: $10–$122 What Is Viorele 28 Day? Viorele 28 Day is a combination oral contraceptive (COC) pill manufactured by Glenmark Pharmaceuticals, Inc. It contains two synthetic female hormones — desogestrel (0.15 mg), a third-generation progestin, and ethinyl estradiol (0.02 mg), a synthetic estrogen — taken together daily to prevent pregnancy. Each 28-day blister pack follows a biphasic schedule: 21 active hormone combination tablets, 2 inactive placebo tablets, and 5 low-dose estrogen-only tablets (0.01 mg... ### Vistaril **Generic:** hydroxyzine Findability: 60/100 | Shortage: active | Insurance: $0–$15 | Cash: $10–$40 What Is Vistaril? Vistaril is the brand name for hydroxyzine pamoate, a first-generation antihistamine that has been used since the 1950s. It belongs to the piperazine class of antihistamines and is available by prescription only in the United States. Hydroxyzine is FDA-approved for the symptomatic relief of anxiety and tension associated with psychoneurosis, the management of allergic pruritus (itching) from conditions such as chronic urticaria and atopic dermatitis, and as a preoperative... ### Vivelle **Generic:** Vivelle Findability: 40/100 | Shortage: active | Insurance: $10-$30 | Cash: $30-$450 What Is Vivelle-Dot and What Does It Do? Vivelle-Dot is a brand-name estradiol transdermal patch used for hormone replacement therapy (HRT) in menopausal and postmenopausal women. It delivers 17β-estradiol through the skin to treat moderate to severe hot flashes, vaginal dryness, and other menopause symptoms. It is also approved for treating hypoestrogenism due to hypogonadism, castration, or primary ovarian failure, and for the prevention of postmenopausal osteoporosis. Vivelle-Dot is... ### Vivotif **Generic:** typhoid vaccine live oral ty21a Findability: 72/100 | Shortage: resolved | Insurance: $0–$168 | Cash: $111–$168 What Is Vivotif? Vivotif is the brand name for typhoid vaccine live oral Ty21a — the only oral typhoid vaccine available in the United States. It is a live attenuated (weakened) bacterial vaccine approved by the FDA for the prevention of typhoid fever in adults and children ages 6 and older. Vivotif is primarily recommended for travelers visiting typhoid-endemic regions (South Asia, sub-Saharan Africa, parts of Latin America and Southeast Asia), household contacts of documented typhoid... ### Voquezna **Generic:** vonoprazan Findability: 60/100 | Insurance: $25–$50 | Cash: $829–$1,013 What Is Voquezna? Voquezna is the brand name for vonoprazan, a first-in-class potassium-competitive acid blocker (PCAB) developed by Phathom Pharmaceuticals. It is the first medication of its class approved in the United States, representing the most significant innovation in acid-suppression therapy in over 30 years. It is available as 10 mg and 20 mg oral tablets, as well as in combination packs (Voquezna Triple Pak and Voquezna Dual Pak) for H. pylori eradication. The FDA approved the... ### Voydeya **Generic:** danicopan Findability: 35/100 | Insurance: $0–$15,000/year | Cash: $4,000–$100,000/year What Is Voydeya? Voydeya (danicopan) is a prescription oral medication and the first FDA-approved complement Factor D inhibitor. It was approved by the FDA on March 29, 2024, and is manufactured by Alexion Pharmaceuticals, Inc. (AstraZeneca). Voydeya is a first-in-class therapy, meaning no other drug in its specific category had been approved for any indication before it. Voydeya is indicated as add-on therapy to ravulizumab (Ultomiris) or eculizumab (Soliris) for the treatment of... ### Vuity **Generic:** pilocarpine hydrochloride ophthalmic solution 1.25% Findability: 78/100 | Insurance: $87–$162 | Cash: $87–$162 What Is Vuity? Vuity (pilocarpine hydrochloride ophthalmic solution 1.25%) is a prescription eye drop manufactured by Allergan, an AbbVie company. It is the first and only FDA-approved prescription medication specifically indicated for the treatment of presbyopia — age-related blurry near vision — in adults. The FDA approved Vuity on October 29, 2021, and a twice-daily dosing option was approved in 2023. Presbyopia affects nearly 128 million Americans and approximately 1.8 billion people... ### Vyleesi **Generic:** bremelanotide Findability: 45/100 | Insurance: $0–$100 | Cash: $290–$1,295 What Is Vyleesi? Vyleesi (bremelanotide) is an FDA-approved prescription injectable medication for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. It was approved by the FDA on June 21, 2019, and is one of only two FDA-approved medications specifically indicated for HSDD (the other being Addyi/flibanserin). Vyleesi is manufactured and distributed by Cosette Pharmaceuticals. Unlike daily pill-based treatments, Vyleesi is an on-demand... ### Vyndamax **Generic:** tafamidis Findability: 55/100 | Insurance: $0–$2,100/yr | Cash: $23,000–$24,500/mo What Is Vyndamax? Vyndamax (tafamidis) is an oral specialty medication manufactured by Pfizer and FDA-approved on May 3, 2019. It is the brand name for tafamidis free acid, a first-in-class transthyretin (TTR) stabilizer. It is indicated for the treatment of the cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM) in adults, to reduce cardiovascular mortality and cardiovascular-related hospitalization. ATTR-CM is a rare, progressive, life-threatening heart... ### Vyvanse **Generic:** Vyvanse Findability: 40/100 | Shortage: active | Insurance: $15–$60 | Cash: $30–$80 What Is Vyvanse? Vyvanse (lisdexamfetamine dimesylate) is a prescription stimulant medication used to treat Attention Deficit Hyperactivity Disorder (ADHD) in children (ages 6+) and adults, and moderate-to-severe Binge Eating Disorder (BED) in adults. It is one of the most widely prescribed ADHD medications in the United States. What makes Vyvanse unique among stimulants is that it's a prodrug — the molecule itself is inactive. After you swallow it, enzymes in your red blood cells convert... ### Wegovy **Generic:** Wegovy Findability: 58/100 | Shortage: monitoring | Insurance: $0–$25 | Cash: $349–$1,349 What Is Wegovy? Wegovy (semaglutide) is a prescription medication approved by the FDA for chronic weight management in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with at least one weight-related condition. It was also approved in 2024 to reduce cardiovascular risk in adults with heart disease who are overweight or obese, and in 2025 for MASH (metabolic dysfunction-associated steatohepatitis). Wegovy is manufactured by Novo Nordisk and contains semaglutide, a GLP-1 receptor agonist.... ### Westhroid **Generic:** thyroid desiccated Findability: 15/100 | Shortage: active | Insurance: $0 | Cash: $24–$80 What Is Westhroid? Westhroid is a brand of natural desiccated thyroid (NDT)—a medication derived from dried, powdered porcine (pig) thyroid glands. It is manufactured by RLC Labs in Phoenix, Arizona, and contains both T4 (levothyroxine, 38 mcg/grain) and T3 (liothyronine, 9 mcg/grain), the two primary hormones produced by the human thyroid gland. Westhroid is used to treat hypothyroidism (underactive thyroid), goiter, and as a diagnostic agent in thyroid suppression tests. Unlike synthetic... ### Wixela Inhub **Generic:** fluticasone propionate and salmeterol Findability: 82/100 | Insurance: $0–$50 | Cash: $55–$230 What Is Wixela Inhub? Wixela Inhub is a prescription combination dry powder inhaler (DPI) containing two active medications: fluticasone propionate, an inhaled corticosteroid (ICS), and salmeterol, a long-acting beta agonist (LABA). It is manufactured by Viatris (formerly Mylan Pharmaceuticals) and was FDA-approved in January 2019 as the first generic version of Advair Diskus. Wixela Inhub is approved for the maintenance treatment of asthma in patients age 4 and older, and for the maintenance... ### Xcopri **Generic:** Xcopri Findability: 68/100 | Shortage: monitoring | Insurance: $20–$50 | Cash: $1,100–$1,650 What Is Xcopri? Xcopri (cenobamate) is a prescription anticonvulsant FDA-approved in November 2019 for the treatment of partial-onset (focal) seizures in adults. It is manufactured by SK Life Science, a subsidiary of SK Biopharmaceuticals. Xcopri has generated significant interest in the epilepsy community because clinical trials showed that up to 21% of patients achieved seizure freedom at the 400 mg dose — a remarkably high rate for add-on therapy in drug-resistant epilepsy. Many of these... ### Xdemvy **Generic:** Xdemvy Findability: 55/100 | Shortage: monitoring | Insurance: $0–$30 | Cash: $600–$2,034 What Is Xdemvy? Xdemvy (Lotilaner ophthalmic solution 0.25%) is the first and only FDA-approved prescription eye drop for the treatment of Demodex blepharitis — a common but often underdiagnosed condition caused by an overpopulation of Demodex mites living on the eyelids and eyelashes. Symptoms include itching, irritation, redness, crusty or flaky eyelids, and a gritty or burning sensation in the eyes. Xdemvy is manufactured by Tarsus Pharmaceuticals, Inc. and was approved by the FDA in 2023. ### Xeljanz XR **Generic:** tofacitinib Findability: 72/100 | Insurance: $0–$200 | Cash: $3,200–$8,712 What Is Xeljanz XR? Xeljanz XR is the extended-release formulation of tofacitinib, an oral Janus kinase (JAK) inhibitor manufactured by Pfizer. The "XR" formulation allows once-daily dosing, offering the same therapeutic effect as the twice-daily immediate-release Xeljanz tablet with greater convenience. It was first approved by the FDA for rheumatoid arthritis in February 2016. Xeljanz XR is FDA-approved for adults with moderately to severely active rheumatoid arthritis (RA), active... ### Xigduo XR **Generic:** dapagliflozin/metformin Findability: 55/100 | Insurance: $0–$50 | Cash: $168–$594 What Is Xigduo XR? Xigduo XR is a brand-name prescription combination tablet manufactured by AstraZeneca, first approved by the FDA on October 29, 2014. It combines two active ingredients: dapagliflozin (an SGLT2 inhibitor, the same ingredient found in Farxiga) and metformin hydrochloride extended-release (a biguanide, the most widely prescribed oral diabetes medication in the world). Together, these two medications work through complementary mechanisms to lower blood sugar levels in adults... ### Xofluza **Generic:** Xofluza Findability: 58/100 | Shortage: monitoring | Insurance: $35–$75 | Cash: $50–$219 What Is Xofluza? Xofluza (baloxavir marboxil) is a prescription antiviral medication for influenza (the flu), manufactured by Genentech (a member of the Roche Group) under license from Shionogi & Co. It was FDA-approved in October 2018 and is indicated for: Treatment of acute uncomplicated influenza in patients ages 5+ who have been symptomatic for no more than 48 hours Post-exposure prophylaxis (prevention) of influenza in patients ages 5+ after contact with someone who has the flu Xofluza... ### Xofluza 80 Mg Dose Pack **Generic:** Xofluza 80 Mg Dose Pack Findability: 55/100 | Shortage: monitoring | Insurance: $35–$75 | Cash: $200–$280 What Is Xofluza 80 Mg Dose Pack and What Does It Do? Xofluza (Baloxavir Marboxil) is a prescription antiviral medication used to treat acute uncomplicated influenza (the flu) in patients aged 5 years and older who have been symptomatic for no more than 48 hours. It is also approved for post-exposure prophylaxis — meaning it can help prevent the flu after close contact with someone who is infected. The 80 mg dose pack is specifically intended for patients weighing 80 kg (approximately 176 lbs)... ### Xulane **Generic:** Xulane Findability: 60/100 | Shortage: monitoring | Insurance: $0–$30 | Cash: $47–$200 What Is Xulane? Xulane is a prescription transdermal contraceptive patch used to prevent pregnancy. It contains two hormones — Norelgestromin (a progestin) and Ethinyl Estradiol (an estrogen) — that are absorbed through the skin over the course of a week. Xulane is a generic version of the discontinued brand Ortho Evra and is manufactured by Mylan Pharmaceuticals (a Viatris company). It is approved for use in women with a BMI under 30 kg/m². ### YF-Vax **Generic:** yellow fever vaccine Findability: 55/100 | Shortage: resolved | Insurance: $0–$40 | Cash: $150–$350 What Is YF-Vax? YF-Vax (Yellow Fever Vaccine) is a live-attenuated viral vaccine manufactured by Sanofi Pasteur, Inc. It is the only FDA-licensed yellow fever vaccine in the United States. YF-Vax is used to prevent yellow fever — a potentially life-threatening viral illness caused by a mosquito-borne flavivirus found in tropical regions of Africa and South America. The vaccine uses the 17D-204 strain of the yellow fever virus, grown in avian leukosis-free chicken embryos. It is formulated... ### Yasmin 28 **Generic:** drospirenone/ethinyl estradiol Findability: 78/100 | Insurance: $0–$30 | Cash: $8–$170 What Is Yasmin 28? Yasmin 28 is a brand-name combination oral contraceptive (birth control pill) manufactured by Bayer HealthCare Pharmaceuticals. Each 28-day blister pack contains 21 active yellow tablets and 7 inert white tablets. Each active tablet contains drospirenone 3 mg and ethinyl estradiol 0.03 mg — a progestin-estrogen combination that prevents ovulation and pregnancy. Yasmin 28 is FDA-approved for the prevention of pregnancy and for the treatment of moderate acne in females 14... ### Yaz 28 **Generic:** drospirenone / ethinyl estradiol Findability: 85/100 | Insurance: $0–$30 | Cash: $6–$226 What Is Yaz 28? Yaz 28 is a combination oral contraceptive pill (birth control pill) manufactured by Bayer HealthCare Pharmaceuticals. It contains two synthetic hormones — drospirenone (a progestin) and ethinyl estradiol (an estrogen) — and comes in a 28-day blister pack containing 24 active pink tablets and 4 white placebo tablets. Yaz 28 is FDA-approved for three indications: prevention of pregnancy (contraception), treatment of premenstrual dysphoric disorder (PMDD), and treatment of... ### Yervoy **Generic:** Yervoy Findability: 45/100 | Shortage: active | Insurance: $0–$5,000 | Cash: $7,308–$35,387 What Is Yervoy? Yervoy (ipilimumab) is a prescription immunotherapy medication made by Bristol Myers Squibb. It is a fully human monoclonal antibody that belongs to a class of drugs called immune checkpoint inhibitors. Yervoy is FDA-approved to treat several types of cancer, including unresectable or metastatic melanoma, advanced renal cell carcinoma, metastatic colorectal cancer with specific biomarkers (MSI-H/dMMR), hepatocellular carcinoma, metastatic non-small cell lung cancer, malignant... ### Yupelri **Generic:** revefenacin Findability: 60/100 | Insurance: $0–$330 | Cash: $1,439–$1,826 What Is Yupelri? Yupelri (revefenacin) is a prescription inhalation solution used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It was FDA-approved on November 9, 2018, and is manufactured by Viatris Specialty LLC. Yupelri is the first and only once-daily long-acting muscarinic antagonist (LAMA) available as a nebulizer solution in the United States. Unlike most COPD bronchodilators — which come as dry powder or pressurized metered-dose inhalers —... ### Yusimry **Generic:** adalimumab-aqvh Findability: 42/100 | Insurance: $0–$50 | Cash: $569–$995 What Is Yusimry? Yusimry (adalimumab-aqvh) is an FDA-approved biosimilar to Humira (adalimumab), the world's former best-selling biologic drug. Developed by Coherus BioSciences and distributed by Meitheal Pharmaceuticals, Yusimry received FDA approval on December 17, 2021 and launched commercially in July 2023. It is the seventh adalimumab biosimilar approved in the United States. A biosimilar is a biological medicine that is highly similar to an already-approved reference product — in this... ### ZTlido **Generic:** lidocaine Findability: 55/100 | Insurance: $0–$150 | Cash: $320–$479 What Is ZTlido? ZTlido is the brand name for lidocaine topical system 1.8%, a prescription patch manufactured by Scilex Pharmaceuticals Inc. It received FDA approval in 2018 and is FDA-approved for the relief of pain associated with post-herpetic neuralgia (PHN) — the persistent burning nerve pain that can last months or years after a shingles infection. Each ZTlido patch is 10 cm × 14 cm and contains 36 mg of lidocaine in a non-aqueous drug-in-adhesive system. Despite containing far less... ### Zafemy **Generic:** norelgestromin/ethinyl estradiol Findability: 72/100 | Insurance: $0–$30 | Cash: $47–$132 What Is Zafemy? Zafemy is a generic prescription birth control patch that delivers two synthetic hormones through your skin once a week. It contains norelgestromin (a progestin) and ethinyl estradiol (a synthetic estrogen) — the same active ingredients that were in the original brand-name patch Ortho Evra, which is no longer manufactured. Zafemy is made by Amneal Pharmaceuticals LLC and was FDA-approved in 2021. Zafemy belongs to the drug class of combination hormonal contraceptives (CHCs).... ### Zarontin **Generic:** ethosuximide Findability: 55/100 | Insurance: $10–$50 | Cash: $34–$580 What Is Zarontin? Zarontin is the brand name for ethosuximide, a succinimide anticonvulsant medication FDA-approved for the treatment of absence (petit mal) epilepsy in patients aged 3 and older. It has been in clinical use since the 1960s and remains the first-line, gold-standard treatment for childhood absence epilepsy. Absence seizures are brief lapses in consciousness—typically 5 to 30 seconds—characterized by a sudden blank stare and temporary unresponsiveness. They can occur dozens to... ### Zelsuvmi **Generic:** Zelsuvmi Findability: 55/100 | Shortage: monitoring | Insurance: $0–$150 w/ copay card | Cash: $1,910–$2,350/kit Zelsuvmi (berdazimer topical gel, 10.3%) is the first FDA-approved at-home topical treatment for molluscum contagiosum (MC) in adults and children 1 year of age and older. Molluscum contagiosum is a common viral skin infection that causes small, raised, flesh-colored bumps — it's especially prevalent in children and can persist for months or years without treatment. Zelsuvmi is applied once daily directly to each MC lesion for up to 12 weeks. The medication comes as a two-tube mixing system:... ### Zenatane **Generic:** isotretinoin Findability: 45/100 | Shortage: active | Insurance: $10–$75 | Cash: $200–$500 What Is Zenatane? Zenatane is a brand name for isotretinoin, an oral retinoid (vitamin A derivative) approved by the FDA to treat severe recalcitrant nodular acne — the kind that hasn't responded to antibiotics, topical retinoids, or other treatments. It is manufactured by Dr. Reddy's Laboratories / Zydus and is available in 10 mg, 20 mg, 30 mg, and 40 mg soft gelatin capsules. Other isotretinoin brands available in the United States include Claravis, Amnesteem, Myorisan, and Absorica. All... ### Zenpep **Generic:** pancrelipase Findability: 55/100 | Insurance: $30–$200 | Cash: $235–$2,490 What Is Zenpep? Zenpep (pancrelipase) is a brand-name prescription medication used to treat exocrine pancreatic insufficiency (EPI) — a condition in which the pancreas cannot produce or deliver enough digestive enzymes to properly break down food. It was first approved by the FDA in 2009 and is currently marketed by Nestlé Health Science through Aimmune Therapeutics, Inc. Zenpep contains three classes of porcine-derived digestive enzymes — lipase, protease, and amylase — in enteric-coated... ### Zenzedi **Generic:** Zenzedi Findability: 35/100 | Shortage: active | Insurance: $10–$50 | Cash: $30–$650 What Is Zenzedi? Zenzedi is a brand-name prescription medication containing dextroamphetamine sulfate, a CNS stimulant in the amphetamine class. It is FDA-approved for treating Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients ages 3–16 and narcolepsy. It is also widely used off-label for adult ADHD. Zenzedi is manufactured by Azurity Pharmaceuticals (formerly Arbor Pharmaceuticals) and comes as an immediate-release tablet taken 1–3 times daily. The typical dose range is... ### Zepbound **Generic:** Zepbound Findability: 55/100 | Shortage: monitoring | Insurance: $25–$150 | Cash: $550–$1,060 What Is Zepbound? Zepbound (tirzepatide) is a prescription injectable medication approved by the FDA in November 2023 for chronic weight management in adults with obesity (BMI ≥ 30) or overweight (BMI ≥ 27) with at least one weight-related comorbidity such as type 2 diabetes, high blood pressure, high cholesterol, or obstructive sleep apnea. It is used alongside a reduced-calorie diet and increased physical activity. Zepbound is manufactured by Eli Lilly and contains the same active... ### Zestril **Generic:** lisinopril Findability: 78/100 | Insurance: $0–$15 | Cash: $6–$27 What Is Zestril (Lisinopril)? Zestril is a brand name for lisinopril, an angiotensin-converting enzyme (ACE) inhibitor. It has been available for nearly 30 years and is one of the most commonly prescribed medications in the United States. Lisinopril is also marketed under the brand names Prinivil (largely discontinued at retail) and Qbrelis (an oral liquid solution). Zestril is FDA-approved for three indications: high blood pressure (hypertension) in adults and children aged 6 and older;... ### Zetia **Generic:** ezetimibe Findability: 92/100 | Insurance: $0–$15 | Cash: $10–$50 What Is Zetia (Ezetimibe)? Zetia is the brand name for ezetimibe, a prescription cholesterol-lowering medication belonging to the drug class known as cholesterol absorption inhibitors. It was FDA-approved in 2002 and is the most widely used non-statin lipid-lowering agent in the United States. Generic ezetimibe has been available since December 2016 following patent expiration. Zetia is FDA-approved to treat primary hyperlipidemia, heterozygous familial hypercholesterolemia (HeFH) in adults... ### Zilxi **Generic:** Zilxi Findability: 45/100 | Shortage: active | Insurance: $25–$150 | Cash: $400–$600 What Is Zilxi? Zilxi (Minocycline Topical Foam 1.5%) is a prescription topical antibiotic approved for the treatment of inflammatory lesions — specifically papules and pustules — associated with rosacea in adults. It is manufactured by Journey Medical Corporation and was the first topical minocycline foam approved by the FDA. Unlike oral minocycline, Zilxi is applied directly to the skin, which helps reduce systemic side effects while targeting facial inflammation. ### Ziprasidone **Generic:** ziprasidone Findability: 78/100 | Insurance: $0–$30 | Cash: $12–$218 What Is Ziprasidone? Ziprasidone (brand name Geodon) is an atypical antipsychotic medication approved by the FDA in 2001. It belongs to the second-generation antipsychotic class and is used primarily to treat schizophrenia and bipolar I disorder. The medication is available as oral capsules (20 mg, 40 mg, 60 mg, and 80 mg) and as an intramuscular injection for use in hospital settings. FDA-approved indications include schizophrenia (oral), acute manic or mixed episodes of bipolar I disorder... ### Zirgan **Generic:** ganciclovir ophthalmic gel Findability: 62/100 | Insurance: $25–$100 | Cash: $35–$650 What Is Zirgan? Zirgan is the brand name for ganciclovir ophthalmic gel 0.15%, a prescription antiviral medication manufactured by Bausch + Lomb. It is indicated for the treatment of acute herpetic keratitis (dendritic ulcers) — a corneal infection caused by herpes simplex virus (HSV) — in adults and pediatric patients aged 2 years and older. FDA approved in September 2009, Zirgan was the first new ophthalmic antiviral approved in the United States in 30 years. Zirgan comes as a sterile,... ### Zoloft **Generic:** sertraline Findability: 72/100 | Insurance: $0–$15 | Cash: $5–$75 What Is Zoloft (Sertraline)? Zoloft is the brand name for sertraline hydrochloride, a selective serotonin reuptake inhibitor (SSRI) and one of the most widely prescribed antidepressants in the United States. It was first approved by the FDA on December 30, 1991. The U.S. patent expired in 2006, and affordable generic sertraline has been widely available since. Today, brand-name Zoloft is marketed by Viatris, while generic sertraline is produced by Accord Healthcare, Cipla USA, Lupin, and... ### Zolpidem **Generic:** Zolpidem Findability: 75/100 | Insurance: $0–$15 | Cash: $10–$115 What Is Zolpidem? Zolpidem is a prescription sedative-hypnotic medication used for the short-term treatment of insomnia, specifically difficulty falling asleep. It belongs to a class of drugs known as "Z-drugs" or non-benzodiazepine hypnotics. Zolpidem is sold under several brand names including Ambien, Ambien CR, Edluar, Intermezzo, and Zolpimist. Zolpidem is intended for short-term use (typically 1–2 weeks) and should be taken immediately before bedtime when you have 7–8 hours available for... ### Zomacton **Generic:** somatropin Findability: 55/100 | Insurance: $0–$150 | Cash: $620–$707 What Is Zomacton? Zomacton is a brand-name prescription growth hormone medication manufactured by Ferring Pharmaceuticals. Its active ingredient is somatropin — a recombinant human growth hormone (rHGH) that is biologically identical to the growth hormone naturally produced by the pituitary gland. Zomacton has been FDA-approved for pediatric growth conditions since 1995 and received approval for adult growth hormone deficiency in January 2018. Zomacton is indicated for pediatric patients with... ### Zoryve **Generic:** roflumilast Findability: 60/100 | Insurance: $0–$150 | Cash: $950–$1,145 What Is Zoryve? Zoryve (roflumilast) is a prescription topical medication manufactured by Arcutis Biotherapeutics, Inc. It is available as a cream (in 0.05%, 0.15%, and 0.3% strengths) and as a foam (0.3%), and is FDA-approved to treat three common inflammatory skin conditions: plaque psoriasis, atopic dermatitis (eczema), and seborrheic dermatitis. First approved by the FDA in July 2022, Zoryve represents a new class of topical dermatology treatment — a phosphodiesterase-4 (PDE4) inhibitor —... ### Zovirax **Generic:** acyclovir Findability: 68/100 | Shortage: active | Insurance: $0–$20 | Cash: $15–$105 What Is Zovirax? Zovirax is the brand name for acyclovir, a prescription antiviral medication first approved by the FDA in 1982. It belongs to the nucleoside analogue antiviral drug class and works by blocking herpes virus DNA replication. Acyclovir is one of the most widely prescribed antivirals in the world and is available in multiple forms: oral capsules, tablets, suspension, topical cream, topical ointment, and intravenous injection. Zovirax treats infections caused by herpes simplex... ### Zurzuvae **Generic:** zuranolone Findability: 45/100 | Insurance: $0–$50 | Cash: $15,900–$18,286 What Is Zurzuvae? Zurzuvae (zuranolone) is a prescription medication approved by the FDA in August 2023 as the first and only oral treatment specifically indicated for postpartum depression (PPD) in adults. It is manufactured by Sage Therapeutics in partnership with Biogen and became commercially available in December 2023. Zurzuvae belongs to a new class of medications called neuroactive steroids (NAS). Unlike SSRIs and SNRIs, which target the serotonin system, Zurzuvae works on the brain's... ### Zyflo **Generic:** zileuton Findability: 72/100 | Insurance: $50–$400 | Cash: $260–$4,000 What Is Zyflo? Zyflo is the brand name for zileuton, an orally active inhibitor of 5-lipoxygenase (5-LOX) — the enzyme that produces inflammatory leukotrienes in the body. It was first approved by the FDA in January 1997 and is manufactured by Chiesi USA, Inc. Zyflo is available in two formulations: Zyflo (immediate-release, 600 mg taken 4 times daily) and Zyflo CR (extended-release, 2 × 600 mg taken twice daily). Zyflo is FDA-approved for the prophylaxis and chronic treatment of asthma in... ### Zyprexa **Generic:** olanzapine Findability: 88/100 | Insurance: $0–$30 | Cash: $10–$190 What Is Zyprexa? Zyprexa is the brand name for olanzapine, a second-generation (atypical) antipsychotic medication manufactured by Eli Lilly and Company. It was first approved by the FDA in 1996 and belongs to the thienobenzodiazepine chemical class. Today, generic olanzapine is widely available from multiple manufacturers at significantly lower cost than the brand. Zyprexa is FDA-approved to treat schizophrenia in adults and adolescents aged 13 and older, and bipolar I disorder (manic or... ### Zyrtec-D XR **Generic:** cetirizine-pseudoephedrine Findability: 80/100 | Insurance: $0–$30 | Cash: $15–$30 What Is Zyrtec-D XR? Zyrtec-D XR is an over-the-counter extended-release combination tablet containing cetirizine hydrochloride 5 mg (a second-generation antihistamine) and pseudoephedrine hydrochloride 120 mg (a nasal decongestant). Each tablet provides up to 12 hours of relief from allergy symptoms and nasal congestion. Manufactured by Kenvue Brands LLC (formerly Johnson & Johnson Consumer), Zyrtec-D XR is FDA-approved for the temporary relief of symptoms due to hay fever (seasonal allergic... ### dotti **Generic:** dotti Findability: 40/100 | Shortage: active | Insurance: $10–$30 | Cash: $26–$191 What Is dotti? Dotti is a brand-name estradiol transdermal patch manufactured by Amneal Pharmaceuticals. It delivers 17β-estradiol — the most potent naturally occurring estrogen — through the skin and into the bloodstream. Dotti is FDA-approved for the treatment of moderate to severe hot flashes and vaginal atrophy caused by menopause, as well as the prevention of postmenopausal osteoporosis. It is applied twice weekly to the lower abdomen or upper buttocks. --- ## Drug Shortage Tracker (2391 drugs tracked; showing top 50 by search volume) Real-time shortage data aggregated from the FDA Drug Shortages database and Medfinder pharmacy availability checks. Each drug has a dedicated page at https://www.medfinder.com/shortage-tracker/{slug}. ### Estradiol Availability Score: 3% | Searches: 6,896 ### Adderall XR **Generic:** Triple-bead Mixed Amphetamine Salts FDA Status: Currently in Shortage | Shortage Start: 08/15/2023 | Availability Score: 1% | Searches: 5,828 ### Adderall **Generic:** Mixed Amphetamine Salts FDA Status: Currently in Shortage | Shortage Start: 08/15/2023 | Availability Score: 1% | Searches: 5,092 ### Vyvanse **Generic:** Lisdexamfetamine Dimesylate FDA Status: Currently in Shortage | Shortage Start: 07/14/2023 | Availability Score: 1% | Searches: 3,649 ### Dotti **Generic:** Estradiol Availability Score: 1% | Searches: 1,924 ### Vivelle **Generic:** Estradiol Availability Score: 2% | Searches: 1,187 ### Premarin **Generic:** estrogens, conjugated (USP) Availability Score: 1% | Searches: 1,062 ### Relexxii **Generic:** Methylphenidate Hydrochloride FDA Status: Available | Availability Score: 1% | Searches: 1,003 Relexxii is available. Medfinder continues to monitor pharmacy availability in real time. ### Zenzedi **Generic:** Dextroamphetamine Sulfate FDA Status: Currently in Shortage | Shortage Start: 08/15/2023 | Availability Score: 2% | Searches: 781 ### Lyllana **Generic:** Estradiol Availability Score: 1% | Searches: 690 ### Ritalin **Generic:** Methylphenidate Hydrochloride FDA Status: Currently in Shortage | Shortage Start: 07/26/2023 | Availability Score: 2% | Searches: 631 ### Focalin XR **Generic:** Dexmethylphenidate Hydrochloride Availability Score: 1% | Searches: 587 ### Dexmethylphenidate XR **Generic:** Dexmethylphenidate Hydrochloride Availability Score: 3% | Searches: 584 ### Divigel **Generic:** Estradiol Availability Score: 2% | Searches: 462 ### Dexedrine XR **Generic:** Dextroamphetamine Sulfate Availability Score: 2% | Searches: 365 ### Amphetamine XR **Generic:** Amphetamine FDA Status: Currently in Shortage | Shortage Start: 08/15/2023 | Availability Score: 2% | Searches: 353 ### Focalin **Generic:** Dexmethylphenidate Hydrochloride Availability Score: 2% | Searches: 349 ### Xelstrym **Generic:** Dextroamphetamine FDA Status: Currently in Shortage | Shortage Start: 08/15/2023 | Availability Score: 0% | Searches: 254 ### Duloxetine Availability Score: 16% | Searches: 251 ### Ella **Generic:** Ulipristal Acetate Shortage Start: 07/23/2026 | Availability Score: 2% | Searches: 194 ### Daytrana **Generic:** Methylphenidate FDA Status: Currently in Shortage | Shortage Start: 02/28/2025 | Availability Score: 1% | Searches: 190 ### Buprenorphine/naloxone Availability Score: 10% | Searches: 180 ### Buprenorphine Availability Score: 0% | Searches: 178 ### Climara **Generic:** Estradiol Availability Score: 1% | Searches: 178 ### Progesterone Shortage Start: 08/31/2026 | Availability Score: 67% | Searches: 173 ### Minivelle **Generic:** Estradiol Availability Score: 2% | Searches: 163 ### Zepbound **Generic:** Tirzepatide Availability Score: 0% | Searches: 158 ### Estradiol/norethindrone Availability Score: 2% | Searches: 152 ### Rivaroxaban Shortage Start: 09/18/2026 | Searches: 135 ### Dextroamphetamine XR Availability Score: 1% | Searches: 122 ### Drysol **Generic:** Aluminum Chloride Availability Score: 3% | Searches: 117 ### Desoxyn **Generic:** Methamphetamine Hydrochloride Availability Score: 1% | Searches: 104 ### Natazia 28 Day **Generic:** Estradiol Valerate Availability Score: 1% | Searches: 104 ### Upneeq **Generic:** Oxymetazoline Hydrochloride Searches: 104 ### Wegovy **Generic:** Semaglutide Shortage Start: 06/04/2026 | Availability Score: 14% | Searches: 102 ### Clonazepam FDA Status: Currently in Shortage | Shortage Start: 03/10/2023 | Availability Score: 29% | Searches: 99 ### Xofluza **Generic:** Baloxavir Marboxil Availability Score: 4% | Searches: 93 ### Xarelto **Generic:** Rivaroxaban Shortage Start: 09/18/2026 | Availability Score: 50% | Searches: 92 ### Journavx **Generic:** Suzetrigine Availability Score: 38% | Searches: 89 ### Azstarys **Generic:** Serdexmethylphenidate and Dexmethylphenidate Availability Score: 4% | Searches: 88 ### Finacea **Generic:** Azelaic Acid Availability Score: 2% | Searches: 80 ### Cepacol Antibacterial Mouthwash **Generic:** Cetylpyridinium Chloride Searches: 79 ### Lantus **Generic:** Insulin Glargine Availability Score: 20% | Searches: 77 ### Apixaban Searches: 75 ### Briviact **Generic:** Brivaracetam Availability Score: 0% | Searches: 67 ### Combipatch **Generic:** Norethindrone Acetate Searches: 67 ### Cromolyn FDA Status: Currently in Shortage | Shortage Start: 11/03/2023 | Availability Score: 8% | Searches: 65 ### Brexafemme **Generic:** Ibrexafungerp Availability Score: 0% | Searches: 64 ### Alprazolam Searches: 60 ### Mounjaro **Generic:** Tirzepatide Searches: 60 --- ## Recent Blog Posts (30 most recent)

### How to Help Your Patients Save Money on Tri-Lo-Sprintec: A Provider's Guide to Savings Programs By Peter Daggett · July 15, 2026 > Patients asking about the cost of Tri-Lo-Sprintec? Here's a comprehensive provider guide to every savings option—from ACA coverage to discount cards and safety-net programs. Cost is one of the leading reasons patients discontinue or don't start oral contraceptives. As a provider, understanding the available savings resources for Tri-Lo-Sprintec 28 Day — and knowing how to communicate them to your patients — can directly improve contraceptive adherence and outcomes. Understanding Tri-Lo-Sprintec's Cost Landscape Tri-Lo-Sprintec is a generic medication manufactured by Teva Pharmaceuticals. Its retail cash price ranges from $100 to $126 per 28-day pack without insurance or a discount card. However, the actual cost paid by most patients is dramatically lower: Commercial insurance with ACA mandate: $0 for most patients GoodRx coupon: As low as $22.20 per pack SingleCare discount card: As low as $8.93 per pack Medicaid: $0 or minimal copay in most states Title X / Planned Parenthood: Sliding scale, potentially $0 The ACA Contraceptive Mandate: Your Most Important Tool Under the Affordable Care Act, non-grandfathered commercial health plans are required to cover at least one form of hormonal contraception in each method category with no cost-sharing. For combination oral contraceptives, this typically means at least one norgestimate/ethinyl estradiol generic is available at $0 copay. Clinical guidance for providers: When prescribing, write for the generic: "norgestimate/ethinyl estradiol triphasic (low dose)" rather than a specific brand. This maximizes formulary flexibility. If a patient's plan doesn't cover Tri-Lo-Sprintec at $0 but...

### Tri-Lo-Sprintec Drug Interactions: What to Avoid and What to Tell Your Doctor By Peter Daggett · July 1, 2026 > Some common medications, supplements, and even foods can reduce how well Tri-Lo-Sprintec works. Here's what to watch out for and what to tell your doctor. Tri-Lo-Sprintec 28 Day is metabolized in the liver, which means many other medications and supplements can affect how well it works. Some interactions reduce its contraceptive effectiveness. Others can increase the risk of side effects. Here's what you need to know. Drugs That Reduce How Well Tri-Lo-Sprintec Works (Enzyme Inducers) The most important category of interactions involves drugs that activate liver enzymes — specifically cytochrome P450 3A4 (CYP3A4). These drugs speed up the breakdown of ethinyl estradiol and norgestimate in your body, reducing their blood levels and potentially making Tri-Lo-Sprintec less effective at preventing pregnancy. If you take any of these medications, use a backup contraceptive method (condoms) while taking them and for 28 days after stopping: Rifampin (rifampicin): Antibiotic for tuberculosis and certain other infections. Considered the most significant interaction — strongly reduces COC effectiveness. Rifabutin, rifapentine: Related antibiotics with similar enzyme-inducing effects. Phenytoin (Dilantin): Anti-seizure medication. Significantly reduces COC effectiveness. Carbamazepine (Tegretol): Anti-seizure and mood-stabilizing medication. Phenobarbital (and other barbiturates): Anti-seizure medications; also used for anxiety. Topiramate (Topamax): Anti-seizure and migraine medication; also used for weight loss. Oxcarbazepine (Trileptal): Anti-seizure medication. Bosentan (Tracleer): Used for pulmonary arterial...

### How Does Tri-Lo-Sprintec Work? Mechanism of Action Explained in Plain English By Peter Daggett · June 15, 2026 > How does Tri-Lo-Sprintec 28 Day actually prevent pregnancy? Here's a plain-English explanation of how its hormones work in your body—and why the triphasic approach matters. Tri-Lo-Sprintec 28 Day works through a combination of hormonal mechanisms that work together to prevent pregnancy. Understanding how it works can help you take it correctly, recognize when it might be less effective, and make informed decisions about your birth control. The Two Hormones: Norgestimate and Ethinyl Estradiol Tri-Lo-Sprintec contains two synthetic hormones that mimic naturally occurring hormones in the body: Norgestimate — a synthetic progestin (progesterone analog). It mimics the hormone progesterone, which your body naturally produces after ovulation. Ethinyl estradiol — a synthetic estrogen. It mimics estradiol, the primary estrogen hormone produced by the ovaries. Tri-Lo-Sprintec uses a low dose of 25 mcg, compared to 35 mcg in Tri-Sprintec. How These Hormones Prevent Pregnancy: Three Mechanisms Tri-Lo-Sprintec prevents pregnancy through three overlapping actions: Mechanism 1: Suppressing Ovulation This is the primary and most important mechanism. The combination of norgestimate and ethinyl estradiol suppresses the hormonal signals from your brain (specifically LH and FSH from the pituitary gland) that trigger the release of an egg from the ovary. No egg, no fertilization — no pregnancy. This works because the synthetic hormones in Tri-Lo-Sprintec create a feedback signal to the pituitary gland, essentially telling the brain "progesterone and estrogen levels are already high," which shuts down the hormonal cascade that triggers ovulation. Mechanism...

### What Is Tri-Lo-Sprintec? Uses, Dosage, and What You Need to Know in 2026 By Peter Daggett · June 1, 2026 > A complete guide to Tri-Lo-Sprintec 28 Day: what it is, what it treats, how to take it, and what makes it different from other birth control pills in 2026. Tri-Lo-Sprintec 28 Day is one of the most widely used combination oral contraceptives in the United States. Here's everything you need to know about it — from what it contains to how to take it correctly — explained in plain language. What Is Tri-Lo-Sprintec? Tri-Lo-Sprintec (norgestimate/ethinyl estradiol) is a combination oral contraceptive (COC) pill that contains two types of hormones: norgestimate (a progestin) and ethinyl estradiol (an estrogen). It is a generic medication made by Teva Pharmaceuticals and is a generic equivalent of the discontinued brand-name Ortho Tri-Cyclen Lo. The name tells you a lot about the drug: "Tri": Triphasic — the hormone doses change three times across the 28-day pack "Lo": Low-dose estrogen — 25 mcg of ethinyl estradiol, vs. 35 mcg in the higher-dose version "28 Day": The pack contains 28 tablets — 21 active hormone pills and 7 inactive (placebo) pills What Is Tri-Lo-Sprintec Used For? The FDA has approved Tri-Lo-Sprintec for one primary use: Prevention of pregnancy (contraception) Beyond pregnancy prevention, many patients and providers also use norgestimate/EE combination pills for off-label benefits, though Tri-Lo-Sprintec is not specifically FDA-approved for these: More regular, lighter, and less painful periods Reduced risk of ovarian cysts Improvement in acne (FDA-approved for Tri-Sprintec, the higher-dose version; class effect may apply) Symptom relief for endometriosis (off-label) What's In the Pack? Dosage...

### How to Check If a Pharmacy Has Tri-Lo-Sprintec 28 Day in Stock (Without Calling) By Peter Daggett · May 15, 2026 > Stop wasting time calling pharmacies. Here's how to check Tri-Lo-Sprintec 28 Day stock in 2026—using apps, insurance portals, and services that do the work for you. Calling pharmacies one by one to check stock is frustrating, time-consuming, and often ends with hold music. Here's how to check whether a pharmacy near you has Tri-Lo-Sprintec 28 Day in stock — faster, and in many cases, without picking up the phone. Method 1: Use medfinder (Fastest Option) medfinder is a service specifically designed to solve this problem. You enter your medication (Tri-Lo-Sprintec 28 Day), dosage, and ZIP code. medfinder then calls pharmacies near you on your behalf to check which ones have it in stock. Results are texted to your phone — no hold music, no repeated calls. medfinder also checks for FDA-equivalent alternatives like Tri-Lo-Estarylla and Tri-Lo-Mili, so if your specific brand isn't available, you'll know which equivalent generic is nearby. Method 2: Check Your Insurance Plan's Pharmacy Portal Many major insurance providers — including UnitedHealth, Aetna, Cigna, CVS/Caremark, and Express Scripts — have online portals or mobile apps that let you search for your medication at in-network pharmacies. Log in to your insurance portal, search for Tri-Lo-Sprintec (or ask for an equivalent generic), and look for nearby pharmacies with availability listed. Note: Not all portals show real-time inventory data. Some show formulary coverage rather than actual stock levels. If your portal shows the drug is covered but doesn't confirm stock, you may still need to call or use medfinder to confirm. Method 3: Use the free MedFinder savings card or a...

### How to Help Your Patients Save Money on Acetaminophen/Caffeine: A Provider's Guide to Savings Programs By Peter Daggett · May 1, 2026 > A provider's guide to helping patients save money on Acetaminophen/Caffeine, including OTC cost strategies, HSA/FSA guidance, and when prescription options make sense. Acetaminophen/caffeine (Excedrin Tension Headache and generics) is one of the most affordable OTC pain relievers available. At $5-$20 for a 24-100 count bottle, it's often not a major financial burden for most patients. However, some patient populations — those on fixed incomes, the uninsured, or those whose plans offer OTC coverage — can benefit from targeted cost-saving guidance. This provider guide covers everything you need to know to help patients access this medication affordably. Understanding the Cost Landscape for OTC Acetaminophen/Caffeine As an over-the-counter product, acetaminophen/caffeine is not covered by most standard health insurance plans without a prescription. This means the patient pays full retail price at the pharmacy counter — typically $6-$18 per branded bottle. However, there are two tiers of cost to understand: Branded (Excedrin Tension Headache): $6-$12 for 24 caplets; $14-$20 for 100 caplets. Manufactured by Haleon (formerly GSK Consumer Healthcare). Generic store brands: $4-$8 for 24-50 tablets; contain identical active ingredients (500 mg acetaminophen + 65 mg caffeine). Available at Walmart (Equate), Target (Up & Up), CVS (CVS Health), and Walgreens (Well at Walgreens). Counseling Point 1: Recommend Generic Store Brands The most impactful thing a provider can do is proactively counsel patients to use store-brand generics. Many patients don't realize that "Equate Tension Headache" at Walmart contains the exact same 500 mg acetaminophen...

### Tri-Lo-Sprintec Side Effects: What to Expect and When to Call Your Doctor By Peter Daggett · May 1, 2026 > Learn what side effects are common with Tri-Lo-Sprintec 28 Day, which ones usually go away on their own, and which symptoms require immediate medical attention. Like all medications, Tri-Lo-Sprintec 28 Day can cause side effects. Most are mild and improve after the first few months. Some are serious and require immediate medical attention. This guide explains what to expect — and what warning signs to never ignore. Boxed Warning: Smoking and Cardiovascular Risk Tri-Lo-Sprintec carries an FDA boxed warning — the strongest safety warning available. Cigarette smoking significantly increases the risk of serious cardiovascular events (blood clots, stroke, heart attack) when combined with COC use. This risk increases with age, especially in women over 35. Tri-Lo-Sprintec is contraindicated in women over 35 who smoke. Women of any age who smoke should discuss this risk with their provider. Common Side Effects (Usually Temporary) These side effects are frequently reported, especially during the first 1–3 months of use. Most improve on their own as your body adjusts: Nausea: Most common in the first few weeks. Taking the pill with food or at bedtime can help. Headache: Mild headaches are common when starting. Persistent or severe headaches warrant a call to your provider. Breast tenderness: Mild breast soreness or fullness, typically improving after the first cycle. Spotting or breakthrough bleeding: Very common in the first 3 months. If heavy or persistent, contact your provider. Mood changes or depression: Some users report mood changes. If you experience significant depression, tell your provider. Decreased sex drive (libido):...

### How to Help Your Patients Save Money on Mifepristone: A Provider's Guide to Savings Programs By Peter Daggett · April 28, 2026 > Mifepristone can be expensive. This provider guide covers every savings resource for Mifeprex and Korlym patients—abortion funds, PAPs, insurance strategies, and prior auth tips. Cost is one of the most significant and underaddressed barriers to mifepristone access for patients. Without insurance coverage, mifepristone for abortion ranges from $50 to $800 depending on the channel, while Korlym for Cushing's syndrome can exceed $15,000 per month at retail. Providers play a critical role in connecting patients with savings resources — but doing so effectively requires knowing what's available, who qualifies, and how to initiate the process efficiently. This guide provides everything your clinical team needs to help patients manage mifepristone costs. Part 1: Cost Assistance for Mifeprex (Medical Abortion) Understanding Insurance Coverage for Medication Abortion Coverage for medication abortion is highly variable and depends on the patient's state of residence, their insurance type, and their plan specifics. In states where abortion is legal, many ACA-compliant insurance plans cover medication abortion as part of reproductive health benefits, reducing patient cost to $0-$30. However, important exceptions apply: The Hyde Amendment prohibits use of federal Medicaid funds for abortion (with limited exceptions for rape, incest, and life endangerment). Some states fund abortions through state Medicaid funds, but this varies. Some states specifically prohibit private insurance from covering abortion — meaning even commercially insured patients in those states may not have coverage. Self-insured employer plans (common for large employers) are governed by...

### Acetaminophen/Caffeine Drug Interactions: What to Avoid and What to Tell Your Doctor By Peter Daggett · April 20, 2026 > Learn which drugs, supplements, and substances interact with Acetaminophen/Caffeine, what's safe to combine, and what to always tell your doctor or pharmacist. Acetaminophen/caffeine (Excedrin Tension Headache) is generally safe for most people when used as directed. But because it contains two active ingredients — acetaminophen and caffeine — both can interact with other medications, supplements, and substances. Here's what you need to know before combining it with anything else. The Most Important Rule: Avoid Double Acetaminophen The number one drug interaction risk with acetaminophen/caffeine is unintentional overdose from combining it with other acetaminophen-containing products. Acetaminophen (abbreviated APAP) is found in hundreds of OTC and prescription products, including: NyQuil, DayQuil, and most cold/flu combination products Tylenol (in all formulations) Prescription opioid combinations: Percocet (oxycodone/acetaminophen), Vicodin/Norco (hydrocodone/acetaminophen), Tylenol with Codeine Fioricet (butalbital/acetaminophen/caffeine) — this is also a prescription headache medication containing acetaminophen Sleep aids: ZzzQuil, Unisom SleepTabs (some formulations) If you take any of these products on the same day as Excedrin Tension Headache, your total acetaminophen dose may exceed the 4,000 mg/day maximum — or the lower safe limit for liver disease patients — putting you at risk for liver damage. Acetaminophen and Warfarin (Blood Thinners): Monitor Carefully Acetaminophen can potentiate the anticoagulant effect of warfarin (Coumadin), increasing the risk of bleeding. This effect is dose-dependent and becomes more...

### Mifepristone Drug Interactions: What to Avoid and What to Tell Your Doctor By Peter Daggett · April 20, 2026 > Mifepristone has significant drug interactions including anticoagulants, CYP3A4 inhibitors, and corticosteroids. Know what to avoid and what to tell your doctor before taking mifepristone. Mifepristone has several important drug interactions that patients — and their providers — need to know about before starting treatment. Because mifepristone is metabolized primarily by a liver enzyme called CYP3A4, drugs that affect this enzyme can significantly raise or lower mifepristone levels in the body. Other interactions relate directly to mifepristone's mechanism of action (blocking progesterone and cortisol receptors). This guide covers the most important interactions for both Mifeprex (abortion) and Korlym (Cushing's syndrome) use. Contraindicated Combinations: Do NOT Use These With Mifepristone The following drug combinations are contraindicated — meaning they should not be used together with mifepristone because the risk of serious harm is too high: Anticoagulants and blood thinners (warfarin, heparin, enoxaparin, apixaban, rivaroxaban, etc.): Mifepristone causes bleeding as part of its mechanism. Combining it with anticoagulants significantly increases the risk of excessive, potentially life-threatening bleeding. This applies to both the abortion and Cushing's uses. Aspirin and NSAIDs (ibuprofen, naproxen): Aspirin inhibits platelet function, which can cause excessive post-abortion bleeding when combined with mifepristone. This is particularly important for Mifeprex use. Note: Ibuprofen may be used for pain relief after misoprostol at the provider's recommendation in specific situations — discuss with your prescriber. Long-term corticosteroid therapy...

### How to Help Your Patients Save Money on Twyneo: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Twyneo can cost nearly $800 without help. This provider guide covers every savings program for Twyneo patients — from the manufacturer card to insurance navigation tips. Cost is one of the primary barriers preventing patients from filling their Twyneo prescriptions. With a retail price that can exceed $700–$800 per 30g pump, many patients abandon the prescription at the pharmacy counter — even when the clinical case for using it is strong. As the prescriber, you play a critical role in connecting patients to savings programs before they give up. This guide covers every option available in 2026. Why Cost Management Matters at the Point of Prescribing Research consistently shows that medication non-adherence is highest when patients are surprised by cost at the pharmacy. Twyneo has no generic, meaning there is no automatic price floor — the retail price is the baseline without a program in place. As a prescriber, proactively mentioning the savings options during the appointment (or having your MA/front desk hand patients a printed resource) dramatically increases the likelihood they will actually fill and use the prescription. Savings Option 1: Mayne Pharma Patient Savings Card The Mayne Pharma Patient Savings Card is the most powerful cost-reduction tool available for Twyneo patients. For commercially insured patients: May pay as little as $0 per prescription. The savings card essentially waives the copay for eligible commercially insured patients. For cash-paying patients: May pay as little as $45 per prescription. Eligibility restriction: NOT available for patients enrolled in Medicare, Medicaid, TRICARE, or other...

### How to Help Your Patients Save Money on Alinia: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Alinia can cost $1,350+ at retail. This provider guide covers manufacturer co-pay programs, generic options, and strategies to help every patient afford nitazoxanide. Prescribing the right medication is only part of the clinical equation. When a 3-day antiparasitic course carries a retail price tag of $1,350 to $1,600, the likelihood of a patient abandoning the prescription at the pharmacy counter is very real. As a provider prescribing Alinia (nitazoxanide), understanding the full cost landscape — and what savings options are available — enables you to improve medication adherence and patient outcomes. Understanding the Cost Landscape Alinia's pricing reflects its status as a brand-name, low-volume specialty medication. Here is the current 2026 pricing picture: Brand Alinia (6 x 500 mg tablets): Average retail $1,350–$1,605 per prescription Generic nitazoxanide (6 x 500 mg): Retail ~$833–$1,113; GoodRx coupon reduces to ~$223 With commercial insurance (generic): Typically $0–$30 at Tier 1–2 With Romark co-pay card (brand, commercially insured): As little as $0 Strategy 1: Prescribe Generic Nitazoxanide — The Simplest Solution The most impactful thing a prescriber can do to reduce Alinia costs is write for the generic. Generic nitazoxanide (FDA-approved 2020) is therapeutically equivalent to brand Alinia — same active ingredient, same strength, same FDA standards. The price difference is enormous: Brand Alinia retail: ~$1,600 → Generic + GoodRx: ~$223 Savings of over 85% by switching to generic for cash-pay patients Prescribing practice recommendation: Write 'nitazoxanide' (generic name) with 'substitution permitted.' This...

### How to Help Your Patients Save Money on Aluminum Hydroxide/Magnesium Hydroxide: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A provider's guide to helping patients reduce costs on aluminum hydroxide/magnesium hydroxide antacids in 2026, including store brands, FSA/HSA benefits, and when to consider alternative drug classes. At first glance, aluminum hydroxide/magnesium hydroxide might seem like a medication that needs no cost counseling — after all, a bottle of generic antacid costs less than $10 at most pharmacies. But for some patient populations, even low-cost OTC items represent a genuine barrier, and your guidance on smarter purchasing, insurance benefits, and when to switch drug classes can make a real difference. Here's what providers should know. Understanding the Cost Landscape for Antacids Aluminum hydroxide/magnesium hydroxide is an OTC product available as a suspension or chewable tablet. The price range in 2026: Brand name (Mylanta Maximum Strength): $12–$15 per 355mL bottle Store-brand generic suspension: $8–$12 at major pharmacy chains With GoodRx coupon: As low as $6–$7 for generic suspension Chewable tablets (generic): $5–$10 per bottle depending on count These prices are already low, but for patients on fixed incomes or those using antacids daily (which may indicate a need to reassess their acid management regimen), small savings add up. Counseling Point #1: Recommend Generic Store Brands Explicitly Many patients assume that brand-name antacids are superior or that the store brand is a lesser product. Clear your patients of this misconception when you recommend antacids. The FDA requires that OTC generic antacids contain the same active ingredients in the same amounts as their brand-name counterparts. A practical counseling script: "The CVS/Walgreens/Walmart store...

### How to Help Your Patients Save Money on Alyacen 1/35: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A practical guide for OB/GYNs, PCPs, and NPs on helping patients reduce the cost of Alyacen 1/35 through ACA mandates, discount cards, Medicaid, and alternative prescribing. Cost is one of the most common reasons patients discontinue oral contraceptives — even when they're working well and are clinically appropriate. As a prescriber, understanding the savings options available for Alyacen 1/35 puts you in a position to proactively address cost barriers before they lead to non-adherence or unintended pregnancy. This guide provides a comprehensive overview of cost-mitigation strategies relevant to Alyacen 1/35 in 2026. The Cost Landscape: What Patients Pay for Alyacen 1/35 The retail (cash) price for Alyacen 1/35 without insurance typically ranges from $25 to $77 per 28-tablet pack. With pharmacy discount cards, patients can often bring this down to $14-$26 per pack. Patients with ACA-compliant commercial insurance are often entitled to $0 cost-sharing. Understanding where each patient falls on this spectrum is the starting point for targeted counseling. ACA Coverage Requirements: The Most Powerful Tool Under the Affordable Care Act, non-grandfathered commercial health plans must cover FDA-approved contraceptive methods — including combination oral contraceptives like Alyacen 1/35 — without cost-sharing (no copay, coinsurance, or deductible). This applies to: Individual and family plans purchased through the ACA marketplaces. Employer-sponsored group health plans (non-grandfathered). Medicaid expansion plans in most states. Key nuances to communicate to patients: Plans may designate a preferred formulary generic. If Alyacen 1/35 is not on...

### How to Help Your Patients Save Money on Anucort-HC: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A practical guide for providers to help patients reduce the cost of Anucort-HC — from generic substitution and coupon programs to patient assistance and insurance strategies. For gastroenterologists, colorectal surgeons, and primary care providers who prescribe Anucort-HC, cost is an increasingly important conversation to have with patients. The retail cash price for a 12-suppository package can exceed $263 — a significant barrier for uninsured patients and those on high-deductible health plans. This guide equips providers with the tools and talking points to help patients access Anucort-HC at a cost they can actually manage. The Cost Challenge: What Patients Actually Pay for Anucort-HC Here's the current pricing landscape for Anucort-HC in 2026: Retail cash price (brand): $200–$264 for a 12-suppository package With GoodRx coupon (brand): As low as $31.90 (88% off retail) Generic (hydrocortisone acetate 25 mg suppository) with GoodRx: As low as $19.12 With some discount cards (SaveHealth): As low as $3.07 in some markets With insurance (generic Tier 1): $0–$15 copay on most formularies Strategy 1: Default to Generic Prescribing — The Single Biggest Cost Lever The most impactful thing you can do to reduce patient cost is to write the prescription generically: "hydrocortisone acetate 25 mg rectal suppository" with DAW-0 (generic substitution permitted). This allows pharmacists to dispense whichever bioequivalent product is in stock at the lowest cost — which is almost always the generic. Clinically, there is no meaningful difference between Anucort-HC brand and generic hydrocortisone acetate 25 mg suppository. Generic prescribing is...

### How to Help Your Patients Save Money on Apomorphine: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A clinical guide for neurologists and prescribers on navigating apomorphine savings programs, prior auth strategy, and patient assistance to reduce cost barriers in 2026. Apomorphine is one of the most effective rescue therapies for advanced Parkinson's disease—but its cost creates a significant access barrier for many patients. Brand Apokyn can retail for over $7,000 for a 15 mL supply, and the new Onapgo infusion device can exceed $8,500–$9,500 per month. Even patients with commercial insurance may face specialty tier copays of hundreds to thousands of dollars. As a prescribing clinician, understanding the savings landscape is critical to ensuring your patients can actually fill and maintain their prescriptions. The Apomorphine Pricing Landscape: What Patients Are Actually Paying Understanding pricing helps you advise patients accurately and identify the most impactful savings strategies. Here are the current price benchmarks: Generic apomorphine injection (TruPharma): Retail ~$1,438 per 3 mL cartridge; with MedFinder, GoodRx from ~$315; with SingleCare ~$454 Brand Apokyn (10 mg/mL, 15 mL): Retail ~$7,228; with manufacturer savings programs, commercially insured patients may pay significantly less Onapgo (continuous infusion, 5 cartridges/6 cartons): ~$8,500–$9,500 cash; no generic; manufacturer support is the primary cost-reduction tool Savings Tool 1: Generic Substitution For Apokyn prescriptions, a generic version of apomorphine hydrochloride injection (10 mg/mL) is available from TruPharma and can substantially reduce costs. When clinically appropriate (and when your patient is on the injection formulation), writing the...

### How to Help Your Patients Save Money on Astagraf XL: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A provider's guide to Astagraf XL savings programs in 2026. Help your kidney transplant patients access copay cards, patient assistance, and Medicare coverage. For transplant nephrologists, transplant coordinators, and social workers managing kidney transplant patients, medication affordability is a direct patient safety issue. Astagraf XL (tacrolimus extended-release capsules) is a brand-only, lifelong medication with retail prices ranging from approximately $95 per month (0.5 mg, 30 capsules) to over $880 per month (5 mg, 30 capsules). Medication non-adherence due to cost is a well-documented cause of transplant rejection -- and it is preventable. This guide reviews all available Astagraf XL savings programs, how to enroll patients, and practical recommendations for building cost management into your transplant follow-up workflow. The Cost Problem: Why Astagraf XL Affordability Matters Clinically Astagraf XL is brand-only with no currently commercially available generic. While the FDA has approved a generic version of tacrolimus XR, it has not yet reached the market. Until it does, all patients on Astagraf XL are paying brand-name prices. For uninsured patients, out-of-pocket monthly costs can reach hundreds to thousands of dollars depending on dose -- costs that can drive non-adherence. Proactive financial screening and enrollment in savings programs at transplant discharge -- and at every follow-up -- should be a standard component of transplant care coordination. Program 1: Astellas Cares Copay Card (Commercially Insured Patients) The Astellas Cares Copay Card is the most impactful savings tool for commercially insured...

### How to Help Your Patients Save Money on Benadryl: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Benadryl is already cheap, but cost still matters. A provider's guide to helping patients save on diphenhydramine with generics, HSA/FSA, discount cards, and community resources. Benadryl (diphenhydramine) may be one of the most affordable medications in existence — but for some patients, even small OTC costs create barriers to medication access. As a clinician, understanding the cost landscape for diphenhydramine and knowing how to guide patients toward the most economical options is a straightforward way to improve adherence and outcomes. This guide equips you with the tools to do that. Understanding the Cost Landscape for Diphenhydramine Diphenhydramine is an OTC medication. This has important implications for cost and coverage: Insurance coverage: Most commercial insurance plans and Medicare Part D do not cover OTC medications. Patients pay out of pocket at retail unless you write a prescription, in which case some plans may cover generic diphenhydramine as a Tier 1 generic (often $0–$10 copay). Retail prices: Generic diphenhydramine 25 mg (30 count): $3–$9 retail. Brand-name Benadryl (24–48 count): $8–$15. Children's liquid (120 mL): $5–$13. With discount cards: MedFinder, GoodRx reduces the price of generic Rx diphenhydramine to as low as $2.82. SingleCare offers comparable discounts. No manufacturer PAP: Johnson & Johnson does not offer a patient assistance program or manufacturer savings card for Benadryl. The generic price is so low that formal assistance programs are unnecessary for most patients. Strategy 1: Write a Prescription for Generic Diphenhydramine For patients on insurance, writing a prescription for diphenhydramine...

### How to Help Your Patients Save Money on Betoptic S: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Betoptic S costs $400–$521 per bottle without help. This provider guide covers the patient assistance programs, prior auth strategies, and cost-saving options to share with your patients. Medication cost is a significant driver of non-adherence in chronic disease management — and glaucoma is no exception. For patients prescribed Betoptic S (betaxolol hydrochloride ophthalmic suspension 0.25%), the retail price of $400–$521 per 10 mL bottle can be a serious barrier to consistent therapy. Non-adherence in glaucoma has direct clinical consequences: inadequate IOP control accelerates optic nerve damage and vision loss. As a prescriber, you can substantially improve patient outcomes by incorporating cost counseling into your practice. This guide gives you the tools to do that efficiently. Why Betoptic S Is So Expensive Betoptic S is a brand-name drug with no FDA-approved generic suspension equivalent. Novartis holds the exclusive market for this specific formulation. Without generic competition, retail pricing is not subject to the downward pressure that drives generic drug prices. The drug's relatively low prescription volume (as prostaglandin analogs have become first-line therapy) further limits market competition. Program 1: Novartis Patient Assistance Foundation (PAF) The Novartis Patient Assistance Foundation is the most impactful program for eligible patients. It provides Novartis medications — including Betoptic S — at no cost to qualifying individuals. Eligibility: Uninsured or underinsured patients with limited household income Benefit: Medication provided at no cost Phone: 1-800-277-2254 Provider role: Prescribers must participate and sign the...

### How to Help Your Patients Save Money on Carboplatin: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Oncology providers: here is a complete guide to carboplatin savings programs, Medicare Part B billing, patient assistance foundations, and financial navigation resources for your patients in 2026. Financial toxicity is a well-documented aspect of cancer care, and carboplatin patients are not immune to it. Even though carboplatin is a generic drug, the total costs of IV administration, clinical monitoring, and supportive medications can create a significant burden — especially for uninsured and underinsured patients. As an oncology provider, your team plays a critical role in connecting patients with savings resources before financial distress affects treatment adherence. This guide covers the full landscape of carboplatin cost assistance in 2026. Understanding How Carboplatin Is Billed Carboplatin is billed under the medical benefit — not the pharmacy benefit — because it is administered intravenously in a clinical setting. This distinction has important implications: Medicare patients: Carboplatin is covered under Medicare Part B at 80% of the Medicare-approved amount after the annual Part B deductible ($257 in 2025). Patients are responsible for 20% coinsurance — which can amount to hundreds of dollars per cycle. Medigap plans (especially Plans G and N) can cover most or all of this coinsurance. Medicare Advantage: Coverage terms vary widely. Some plans have favorable outpatient chemotherapy cost-sharing; others have higher copays or coinsurance. Verify the patient's specific plan terms before initiating treatment. Commercial insurance: Carboplatin is covered under the medical benefit for most commercial plans. Out-of-pocket costs depend on the patient's...

### How to Help Your Patients Save Money on Colestipol: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A practical provider guide to Colestipol cost savings in 2026: formulary tiers, discount cards, patient assistance, and prescribing tips to reduce cost. Colestipol is a generic medication with multiple suppliers, and for most insured patients it is affordable. However, specific clinical scenarios — particularly when patients are uninsured, underinsured, or using the more expensive brand or flavored granule formulations — can result in significant out-of-pocket costs. This guide provides practical guidance for prescribers and care teams on navigating Colestipol affordability. Colestipol Pricing Overview for Prescribers Understanding the price landscape helps you set patient expectations and recommend savings strategies at the point of prescribing: Generic Colestipol tablets (30-day supply): Average retail $20–$58; with MedFinder, GoodRx as low as ~$22; with SingleCare as low as ~$35 for 60 tablets Brand-name Colestid (60 tablets): Average retail ~$181 — significantly higher than generic Flavored Colestid granules: Average retail $243–$289 per month — avoid prescribing unless medically necessary for adherence Insurance (insured patients): Generic Colestipol is typically Tier 1 or Tier 2 on most formularies. Copays generally $5–$20 per month. Insurance Coverage: What to Expect Generic Colestipol is well-covered by most commercial insurance plans and Medicare Part D. As an older, multi-source generic on a standard formulary, it typically requires no prior authorization and carries a Tier 1 or Tier 2 copay. Where coverage gaps can arise: High-deductible plans: Before the deductible is met, patients pay full retail...

### How to Help Your Patients Save Money on Denorex Extra Strength: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > As an OTC product, Denorex Extra Strength has unique savings opportunities. Here is a provider guide to FSA/HSA eligibility, generics, and patient cost reduction strategies. When providers recommend Denorex Extra Strength or similar OTC scalp treatments, the cost conversation is often overlooked — because the product doesn't require a prescription, it seems like it should just be affordable. But for patients with chronic scalp conditions who use these products on an ongoing basis, costs add up. And the OTC landscape has unique financial tools that prescription medications don't. This guide helps you navigate the savings conversation for your patients. Understanding the OTC Cost Landscape for Scalp Treatments Unlike prescription medications, OTC products like Denorex Extra Strength: Are not covered by health insurance under standard pharmacy benefits Do not appear on prescription drug formularies Cannot be discounted through MedFinder, GoodRx, SingleCare, or other prescription coupons Do not have traditional manufacturer patient assistance programs (PAPs) This means providers need to think differently about the savings conversation for OTC scalp treatments — focusing on FSA/HSA benefits, retail strategies, and generic substitution rather than prescription benefit navigation. FSA and HSA Eligibility: The Most Powerful Savings Tool for OTC Patients Since the CARES Act of 2020, OTC drugs and medicines are permanently eligible for FSA (Flexible Spending Account) and HSA (Health Savings Account) reimbursement without a prescription. This is a significant benefit that many patients don't know about. For eligible patients, purchasing Denorex...

### How to Help Your Patients Save Money on Doryx: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Doryx MPC can cost over $700 without coverage. This provider guide covers all available savings programs, prior auth strategies, and alternatives to help patients access their medication affordably. Doryx MPC is a brand-name tetracycline antibiotic without a widely available generic equivalent as of 2026. At retail prices ranging from $700 to over $1,600 per monthly supply, cost is frequently a barrier that drives patients to discontinue treatment or seek alternatives that may not be clinically equivalent. As the prescriber, you are often the first person who can help navigate this — and there are several effective programs available. Understanding the Cost Landscape Before reaching for the prescription pad, it's useful to understand why Doryx MPC is expensive: No true generic equivalent is commercially available (as of 2026) Brand-name drugs without generic competition face minimal pricing pressure Insurance formulary placement varies widely — Doryx MPC may be on a higher tier or require PA However, the net cost to patients can be dramatically reduced through manufacturer programs, coupon services, and formulary management — often to $25 or less per month. Program 1: Mayne Pharma Patient Savings Card Mayne Pharma, the manufacturer of Doryx MPC, offers a patient savings card for commercially insured patients. Key details: Available to patients with commercial (private) insurance only Not available to patients with Medicare, Medicaid, or other federal/state healthcare programs Can reduce patient copay to as little as $0/month for eligible patients Enrollment: patients can register at doryx.com or call 866-316-7263 Clinical recommendation: Consider printing...

### How to Help Your Patients Save Money on Dutasteride/Tamsulosin: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A provider guide to helping BPH patients reduce the cost of dutasteride/tamsulosin (Jalyn) in 2026 — from PAP applications to generic switching and formulary optimization strategies. For urologists, primary care physicians, and other prescribers managing patients on dutasteride/tamsulosin (Jalyn) for BPH, cost is a real barrier to adherence. Brand-name Jalyn carries a retail price exceeding $1,900 per 30-day supply — one of the most expensive options in the BPH drug class. Even generic dutasteride/tamsulosin can cost $150+ per month without assistance. This guide provides a comprehensive overview of the savings strategies available to your patients and how your practice can help them access those resources. Step 1: Default to Generic Dutasteride/Tamsulosin The most impactful single action you can take is ensuring the prescription is written for generic dutasteride/tamsulosin 0.5 mg/0.4 mg capsules — not brand-name Jalyn. If you write "Jalyn" and your e-prescribing system defaults to brand-name, the cost impact on the patient is enormous. Confirm that: DAW (Dispense As Written) is NOT checked, allowing generic substitution The prescription reads "dutasteride/tamsulosin 0.5 mg/0.4 mg" or explicitly permits generic substitution 90-day supplies are allowed when clinically appropriate — most plans offer lower per-unit copays for 90-day fills Step 2: Consider Prescribing the Components Separately For patients who need further cost reduction, prescribing the two components separately often yields lower total drug costs: Generic dutasteride 0.5 mg (30 capsules): ~$15–$40 with MedFinder, GoodRx or SingleCare coupons Generic tamsulosin 0.4 mg (30...

### How to Help Your Patients Save Money on Elahere: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A provider guide to helping patients access financial assistance for Elahere (mirvetuximab soravtansine-gynx), including co-pay cards, PAP programs, and appeals strategies. Elahere (mirvetuximab soravtansine-gynx) is a transformative therapy for patients with FRα-positive, platinum-resistant ovarian cancer — but at approximately $29,307 per treatment cycle, cost and coverage issues frequently delay or prevent treatment initiation. For oncology practices and their teams, proactive engagement with financial assistance resources is essential to ensuring patients can actually begin and sustain Elahere therapy. This provider guide covers every major savings pathway available in 2026. Understanding How Elahere Is Billed: Medical Benefit vs. Pharmacy Benefit Elahere is billed through the medical benefit (under Part B for Medicare patients), not the pharmacy benefit. This distinction matters significantly for patient cost-sharing: Under the medical benefit, patients with commercial insurance typically pay a coinsurance percentage (e.g., 20%) after meeting their deductible — which can be very costly for a high-priced biologic. Medicare Part B enrollees face a standard 20% coinsurance with no out-of-pocket cap (until the annual deductible/MOOP thresholds apply), meaning costs can run to tens of thousands per year without supplemental coverage. Standard pharmacy discount programs (MedFinder, GoodRx, SingleCare, etc.) do not apply to medical-benefit drugs. Program 1: ELAHERE Support Services (ESS) — Co-Pay Assistance AbbVie's ELAHERE Support Services program is the primary resource for patient financial assistance. Your practice should enroll...

### How to Help Your Patients Save Money on Epaned: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Epaned can cost over $400 per bottle without insurance. Here's a provider's guide to patient assistance programs, copay cards, and formulary strategies to reduce cost. Epaned (enalapril maleate oral solution, 1 mg/mL) presents a double access barrier for many patients: it's hard to find at pharmacies, and when patients do find it, they often discover their insurance doesn't cover it. The average retail price for a 150 mL bottle exceeds $418 — a significant monthly burden, particularly for families managing a child's chronic condition. As a prescriber, you're often the first person a patient turns to when they can't afford their medication. Having a clear action plan — and knowing which savings programs exist — can prevent therapy gaps and improve outcomes. Understanding the Coverage Landscape for Epaned Epaned's insurance coverage situation in 2026: Medicare Part D: Most Medicare Part D plans do not cover Epaned as a brand-only liquid formulation. Patients on Medicare may need to pay fully out of pocket. Commercial insurance: Coverage varies significantly by plan. Epaned may be on formulary (often at higher tiers requiring copays) or may require prior authorization. Many commercial plans do not cover it without a PA. Medicaid: Epaned is reimbursed by Medicaid in all states, making it accessible for your low-income pediatric and adult patients who qualify. Specific coverage terms and any required steps (like PA) vary by state. CHIP: Children's Health Insurance Program (CHIP) typically covers medications for pediatric conditions — Epaned for pediatric hypertension should generally be covered. Verify with the state CHIP program if...

### How to Help Your Patients Save Money on Epclusa: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A provider's guide to Epclusa savings programs in 2026: Gilead Support Path, co-pay cards, Medicaid, Medicare, patient assistance, and authorized generic options. With a list price of approximately $24,350 for a 28-day supply, Epclusa's cost can be an immediate barrier when patients see the price tag on their prescription. But the reality is that most patients — with the right guidance — can access Epclusa at a dramatically reduced cost or no cost at all. As a provider, knowing the available savings pathways is critical for ensuring that your patients actually start and complete treatment. This guide organizes the key savings programs by patient insurance status, so you can quickly direct each patient to the right resource. For Commercially Insured Patients: Gilead Support Path Co-Pay Card The most widely applicable savings tool for commercially insured patients is the Gilead Support Path Co-Pay Savings Card. Here are the key clinical and administrative details: Patient cost: As low as $5/month Benefit structure: Covers up to 25% of the catalog price for 3 bottles over 6 months (no monthly limit within that cap) Eligibility: Must have commercial (employer or marketplace) insurance; US citizen 18+ or eligible minor; valid Epclusa prescription; NOT on government insurance (Medicare/Medicaid) Enrollment: MySupportPath.com or 1-855-769-7284 (Mon–Fri, 9 AM–8 PM ET) Important note for providers: If your patient's insurer uses a co-pay accumulator or co-pay maximizer program, the co-pay card funds may not count toward their deductible. In these cases, Gilead may reduce the assistance available. Advise patients to call Support Path to...

### How to Help Your Patients Save Money on Epidiolex: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Epidiolex's cost can be a barrier even with insurance. Here's a complete guide for neurologists and prescribers on JazzCares savings programs, PAP, and cost-reduction strategies in 2026. For neurologists and epileptologists managing patients with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex, cost is one of the most significant barriers to successful Epidiolex treatment. Without proactive cost management, many families cannot sustain long-term therapy — even after a successful prior authorization. This guide provides a comprehensive overview of every available savings program and strategy for helping your patients afford Epidiolex in 2026. Understanding the Cost Landscape for Epidiolex Epidiolex is a brand-only specialty drug with no generic equivalent. At wholesale acquisition cost (WAC), a single 100 mL bottle was priced at $1,310 in 2020; current pricing is higher. For a 20 kg child on 10 mg/kg twice daily (20 mg/kg/day), monthly medication cost can approach or exceed $2,500-$3,000 per month at retail. This makes affordability programs not optional, but essential infrastructure for most Epidiolex patients. The good news: Jazz Pharmaceuticals has built a comprehensive support infrastructure through JazzCares that addresses most affordability scenarios — from commercially insured patients to uninsured families. Knowing how to activate these resources for your patients is a core competency for any prescriber. Program 1: JazzCares Copay Savings Program The JazzCares Copay Savings Program is the primary manufacturer assistance program for commercially insured patients. Key parameters: Eligibility: Commercially insured patients....

### How to Help Your Patients Save Money on Evenity: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > Evenity's $2,600+/month cost is a barrier for many patients. A provider's guide to Amgen SupportPlus, Medicare strategies, nonprofit foundations, and appeal tactics. The clinical case for Evenity (romosozumab) is clear for patients at very high fracture risk. The financial barrier is equally clear: Evenity's list price exceeds $2,600 per monthly dose, totaling over $31,500 for the 12-month course. Cost-driven abandonment of osteoporosis therapy is associated with increased fracture rates — and fractures in elderly women carry significant morbidity and mortality. This guide equips prescribers and their care teams with actionable tools to help eligible patients access Evenity at an affordable cost. Understanding the Cost Landscape for Your Patients Before identifying savings pathways, understand which coverage category applies to each patient: Commercial insurance (employer-sponsored or private): Eligible for Amgen SupportPlus Co-Pay Program. Often the best outcome possible — costs can reach $0/dose. Medicare Part B (in-office administration): Medicare covers 80% after deductible (Part B). Medigap or Medicare Advantage plans often cover the remaining 20%. Data suggests ~87% of Medicare Part B patients pay $0 per dose with supplemental coverage. Medicare Part D (specialty pharmacy route): Tier 4-5 specialty. Coinsurance 25-33%. 2026 out-of-pocket cap: $2,100/year. Manufacturer co-pay cards cannot be used for Medicare patients (federal anti-kickback statutes). Uninsured / underinsured: Amgen Safety Net Foundation provides free medication. Nonprofit foundations also available. Program 1: Amgen SupportPlus Co-Pay Program (Commercially...

### How to Help Your Patients Save Money on Ezetimibe: A Provider's Guide to Savings Programs By Peter Daggett · April 16, 2026 > A clinical guide for providers on ezetimibe cost-reduction strategies: GoodRx, patient assistance programs, formulary optimization, and how to help uninsured patients access this medication. Medication cost is one of the most common barriers to adherence — and ezetimibe, despite being an affordable generic, still presents cost challenges for some patient populations. This guide is designed to help clinicians and care teams quickly identify which cost-reduction strategy is appropriate for a given patient, reducing the financial barrier to guideline-recommended cholesterol management. Understanding the Ezetimibe Cost Landscape The retail price of ezetimibe without insurance varies widely depending on pharmacy and which generic manufacturer is stocked — from roughly $15 at some retailers to over $280 at others. This wide range creates confusion for patients and providers alike. The key facts to know: Generic ezetimibe 10 mg is classified as a Tier 1 or Tier 2 preferred generic on most commercial and Medicare Part D formularies, with typical copays of $0-$15/month. GoodRx coupons can reduce ezetimibe to as little as $10.01 for a 30-day supply at many major chains. SingleCare and Blink Health offer 90-day supplies for as low as $13.89 at participating pharmacies. Brand Zetia is significantly more expensive and should be prescribed only when there is a specific clinical reason to avoid the generic. Strategy 1: Prescribe Generic Ezetimibe Explicitly The single most impactful action a prescriber can take is to write the prescription as "generic ezetimibe" and check the "Dispense As Written" (DAW) box only when brand is clinically necessary. In EHR systems,...